• Transactions of the Korean Society of Automotive Engineers
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• v.17 no.5
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• pp.97-106
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• 2009

An objective of this study is to give practical information that could be used for calculating pollutant emission factors and fuel economy from Korean Inspection & Maintenance program, which has been using steady state acceleration simulation mode. Concentration results from I/M test is adequately converted to mass emission factors and fuel efficiency data, which have unit of g/km and km/L, respectively. Exhaust volume flow(EVF), which is for converting emission result from concentration to mass, is measured by tracer method in various vehicle speed - power condition. It is found that there is an apparent second order relationship between EVF and vehicle inertia weight. EVF is expressed in function of vehicle inertia weight in order to estimate EVF in I/M site without measuring device. Converted mass emission results from measured EVF and raw emission analyzer show a satisfactory agreement with those from conventional CVS-bag type measurement system. Mass emission factors and fuel efficiency from measured EVF and estimated EVF also show good agreement to each other. Considering that an I/M program has great advantages to recruit-based emission test in terms of the number of test vehicle, the information in this study can be used for developing an alternative procedure to collect more various data to establish national database of mobile emission factors and fuel economy, even though the driving cycle in I/M program is steady state cycle rather than transient cycle.

• Journal of Biomedical Engineering Research
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• v.24 no.3
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• pp.193-201
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• 2003

In this paper, a classifier of urine analysis system was designed using preprocessing and fuzzy algorithm. Preprocessing were processed by normalizing data of strip using calibration curve composed of achromatic colors value and by calculating three stimulus. FUZZY classifier capable of analyzing a qualitative concentration of test items was composed of fuzzifier by gaussian shaped membership function, inference of MIN method, and defuzzifier of centroid method through verification by measuring standard solution and by classifying concentration classes. After tuning membership function according to relating standard solution with urinalysis sample, the possibility to adapt classifier designed for urine analysis system near a bed was verified as classifying measured urinalysis samples and observing classified result. Of all test items, experimental results showed a satisfactory agreement with test results of reference system.

• Journal of the Korean Applied Science and Technology
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• v.38 no.2
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• pp.488-496
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• 2021

In this study, a study was conducted to utilize Orostachys japonica A. Berger EtOAc fraction extract as an antibacterial activity and cosmetic ingredient. As a result of measuring the antimicrobial activity of Orostachys japonica A. Berger EtOAc, the growth of S. aureus, S. epidermidis, and P. aeruginosa was inhibited. Among them, S. aureus was an extract of 18.35 ± 1.5 mm Orostachys japonica A. Berger EtOAc fraction at a concentration of 0.5 g / mL, showing superior antibacterial activity than methyl paraben (16.83 ± 1.0 mm), and was shown as a positive control. As a result of evaluating the MIC of the Orostachys japonica A. Berger EtOAc fraction extract through MIC measurement, the remaining strains excluding Candida. A showed a MIC of 17.5 mg/mL. As a result of evaluating the cosmetic preservation effect through the challenge test applied to the cosmetic emulsion formulation, the growth inhibitory effect of S. aureus in the emulsion containing 0.3% Orostachys japonica A. Berger EtOAc fraction extract 7 days after microbial inoculation was 100%.

• Archives of Pharmacal Research
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• v.29 no.4
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• pp.328-332
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• 2006

The bioequivalence and pharmacokinetics of alendronate sodium tablets were examined by determining the plasma concentration of alendronate. Two groups, consisting of 24 healthy volunteers, each received a 70 mg reference alendronate sodium tablet and a test tablet in a $2{\times}2$ crossover study. There was a 6-day washout period between doses. The plasma alendronate concentration was monitored for 7 h after the dose, using HPLC-Fluorescence Detector (FD). The area under the plasma concentration-time curve from time 0 to the last sampling time at 7 h $(AUC_{0-7h})$ was calculated using the linear-log trapezoidal rule. The maximum plasma drug concentration $(C_{max})$ and the time to reach $C_{max}(T_{max})$ were derived from the plasma concentration-time data. Analysis of variance was performed using logarithmically transformed $AUC_{0-7h}\;and\;C_{max}$, and untransformed $T_{max}$. For the test medication versus the reference medication, the $AUC_{0-7h}\;were\;87.63{\pm}29.27\;vs.\;102.44{\pm}69.96ng\;h\;mL^{-1}$ and the $C_{max}$ values were $34.29{\pm}13.77\;vs.\;38.47{\pm}24.39ng\;mL^{-1}$ respectively. The $90\%$ confidence intervals of the mean differences of the logarithmic transformed $AUC_{0-7h}$ and $C_{max}$ values were log 0.8234-log 1.1597 and log 0.8222-log 1.1409, respectively, satisfying the bioequivalence criteria guidelines of both the US Food and Drug Administration and the Korea Food and Drug Administration. The other pharmacokinetic parameters for the test drug versus reference drug, respectively, were: $t_{1/2},\;1.87{\pm}0.62\;vs.\;1.77{\pm}0.54\;h;\;V/F,\;2061.30{\pm}986.49\;vs.\;2576.45{\pm}1826.05\;L;\;CL/F,\;835.32{\pm}357.35\;vs.\;889.48{\pm}485.87\;L\;h^{-1}; K_{el},\;0.42{\pm}0.14\;vs.\;0.40{\pm}0.18\;h^{-1};\;Ka,\;4.46{\pm}3.63\;vs.\;3.80{\pm}3.64\;h^{-1};\;and\;T_{lag},\;0.19{\pm}0.09\;vs.\;0.18{\pm}0.06\;h$. These results indicated that two alendronate formulations(70-mg alendronate sodium) were biologically equivalent and can be prescribed interchangeably.

• Journal of ILASS-Korea
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• v.1 no.3
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• pp.20-28
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• 1996

It is well known that drag reduction in single phase liquid flow is affected by polymer material, molecular weight, polymer concentration, pipe diameter, and flow velocity. Drag reduction in two phase flow can be applied to the transport of crude oil, phase change system such as chemical reactor, pool and boiling flow, and to present cavitation which occurs in pump impellers. But the research of drag reduction in two phase flow is not sufficient. The purpose of the present work is to evaluate the drag reduction by measuring pressure drop, void fraction whether polymer is added in the horizontal two phase system or not. Experiment has been conducted in a test section with 24 m of the inner diameter and 1,500 mm of the length. The used polymer materials are two kinds of polyacrylamide[PAAM] and co-polymer[A611P]. The polymer concentration was varied with 50, 100 and 200 ppm under the same experimental conditions. Experimental results were shown that the drag is higher reduced by co-polymer rather than polyanylamide.

• Journal of Mechanical Science and Technology
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• v.20 no.12
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• pp.2284-2291
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• 2006

The present study investigates gas residence time and mixing characteristics for various swirl numbers generated by injection of secondary air into a lab-scale cylindrical combustor. Fine dust particles and butane gas were injected into the test chamber to study the gas residence time and mixing characteristics, respectively. The mixing characteristics were evaluated by standard deviation value of trace gas concentration at different measurement points. The measurement points were located 25 mm above the secondary air injection position. The trace gas concentration was detected by a gas analyzer. The gas residence time was estimated by measuring the temporal pressure difference across a filter media where the particles were captured. The swirl number of 20 for secondary air injection angle of 5$^{\circ}$ gave the best condition: long gas residence time and good mixing performance. Numerical calculations were also carried out to study the physical meanings of the experimental results, which showed good agreement with numerical results.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.2
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• pp.239-245
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• 2013

In in vitro study, the anti-platelet aggregation effect of Shiitake mushroom extract was examined by measuring the collagen induced platelet aggregation and the DPPH radical scavenging. In in vitro study, anti-thrombotic effect of Shiitake mushroom extract was examined using the carotid artery thrombosis rat model. Carotid artery thrombosis rat model was made by 35% $FeCl_3$ treatment. After that, we investigate thrombus weight and blood flow. In platelet aggregation test, the extract significantly inhibited platelet aggregation in a concentration dependent manner(p<.001). Also, extract increased DPPH radical scavenging activity in a concentration dependent manner. Extract significantly inhibited thrombus weight to compare with control group. And blood passage time were shorter in the Shiitake mushroom extract supplemented groups than in control group. These results provide experimental evidence that Shiitake mushroom can be used to prevent platelet aggregation and thrombosis, then could apply the clinical diseases such as cardiovascular disease, and so on.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.8 no.2
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• pp.198-207
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• 1996

It is well known that drag reduction in single phase liquid flow is affected by polymer material, molecular weight, polymer concentration, pipe diameter, and flow velocity. Drag reduction in two phase flow can be applied to the transport of crude oil, phase change system such as chemical reactor, pool and boiling flow, and to present cavitation which occurs in pump impellers. But the research of drag reduction in two phase flow is not sufficient. The purpose of the present work is to evaluate the drag reduction by measuring pressure drop, void fraction, mean liquid velocity, and turbulent intensity whether polymer is added in the horizontal two phase system or not. Experiment has been conducted in a test section with the inner diameter of 24mm and the length of 1,500mm. The polymer materials used are two kinds of polyacrylamide[PAAM] and co-polymer[A611P]. The polymer concentration was varied with 50, 100 and 200 ppm under the same experimental conditions. Experimental results showed that the drag reduction of co-polymer is higher than that of polyacrylamide. Mean liquid velocities increased as polymer was added, and turbulent intensity decreased inversely near the pipe wall.

• Journal of Korea Foundry Society
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• v.28 no.5
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• pp.237-241
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• 2008

This study has been carried out to investigate the wear and heat resistant properties of durable moldwash agent for Al gravity casting according to mold washing process conditions. The wear properties of coated specimen were performed by sliding wear testing machine and heat resistance were evaluated by measuring the loss of coated moldwash agent during emerging of coated specimen in Al melts. During testing, experimental variables were mold surface temperature, moldwash agent/distilled wear, and additive concentrations. The lower additive concentration and mold temperature caused the smooth surface roughness of coated specimen, It was found that the specimen coated with moldwash/water ratio 1:3, additive concentration 9wt% and mold temperature higher than $200^{\circ}C$ showed superior wear and heat treatment. Also, these results were supported by fluidity test.

• Nuclear Engineering and Technology
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• v.39 no.4
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• pp.327-336
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• 2007

The influence of density differences on the mixing of the primary loop inventory and the Emergency Core Cooling (ECC) water in the downcomer of a Pressurised Water Reactor (PWR) was analyzed at the ROssendorf COolant Mixing (ROCOM) test facility. ROCOM is a 1:5 scaled model of a German PWR, and has been designed for coolant mixing studies. It is equipped with advanced instrumentation, which delivers high-resolution information for temperature or boron concentration fields. This paper presents a ROCOM experiment in which water with higher density was injected into a cold leg of the reactor model. Wire-mesh sensors measuring the tracer concentration were installed in the cold leg and upper and lower part of the downcomer. The experiment was run with 5% of the design flow rate in one loop and 10% density difference between the ECC and loop water especially for the validation of the Computational Fluid Dynamics (CFD) software ANSYS CFX. A mesh with two million control volumes was used for the calculations. The effects of turbulence on the mean flow were modelled with a Reynolds stress turbulence model. The results of the experiment and of the numerical calculations show that mixing is dominated by buoyancy effects: At higher mass flow rates (close to nominal conditions) the injected slug propagates in the circumferential direction around the core barrel. Buoyancy effects reduce this circumferential propagation. Therefore, density effects play an important role during natural convection with ECC injection in PWRs. ANSYS CFX was able to predict the observed flow patterns and mixing phenomena quite well.