• Journal of Microbiology and Biotechnology
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• 제6권4호
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• pp.265-269
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• 1996

An isolate of Streptomyces rochei synonym was found to produce antibiotics with narrow anti-microbial spectrum against Streptococcus and Xanthomonas sp. Among the antibiotic complex produced by the strain, the main active compound was isolated, and its physico-chemical properties and biological activities were investigated. Molecular weight of the compound was determined to be ${[M+H]}^+$ 797 (FAB-MS). UV, $^1H \;and\;^{13}C$ NMR, and IR spectra suggested that the compound is a kirromycin-like aurodox group antibiotic. However, the anti-microbial spectrum of the main compound was slightly different from that of kirromycin. In addition, it was newly found that kirromycin showed a selective anti-microbial activity against Streptococcus pyogenes and phytopathogenic Xanthomonas sp.

• 생약학회지
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• 제27권4호
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• pp.336-341
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• 1996

The roots of Korean Astragalus membranaceus Bunge. (Leguminosae), Astragali Radix, were extracted following general methods. During these extractions, first of all, 1,2-benzendicarboxylic acid diisononylester(compound A), ${\beta}-sitosterol(compound\;B)$, $3-0-{\beta}-D-galactopyranosyl-{\beta}-sitosterol(compound\;C)$ and $stigmast-4-en-6{\beta}-ol-3-one(compound\;D)$ were isolated. Three of these compounds were identified the first time isolation from the genus of Astragalus.

• International Journal of Aeronautical and Space Sciences
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• 제18권4호
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• pp.641-650
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• 2017

In order to include the design capability for a compound rotorcraft in a helicopter conceptual design and optimization framework, relevant further improvement was planned and conducted. Previously, a certain conceptual design optimization framework was developed by the present authors to design a modern rotorcraft with single main and tail rotor. The previously developed framework was further improved to expand its capability for a compound rotorcraft. Specifically, its power estimation algorithm was upgraded by using a comprehensive rotorcraft analysis program, CAMRAD II. The presently improved conceptual design and optimization framework was validated using data of the XH-59A aircraft.

• 한국응용과학기술학회지
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• 제27권1호
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• pp.6-13
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• 2010

Esterification reaction between succinic acid and 1,4-butanediol was kinetically investigated in the presence of nontoxic organometallic compound catalyst(ESCAT-100E) at $150-190^{\circ}C$. The reaction rates measured by the amount of distilled water from the reaction vessel. The Esterification reaction was carried out under the first order conditions respect to the concentration of reactants, respectively. The overall reaction order was 2nd. The linear relationship was shown between apparent reaction rate constant and reciprocal absolute temperature. By the Arrhenius plot the activation energy have been calculated as 376.13 kJ/mol under nontoxic organometallic compound catalyst and also apparent reaction rate constant, k' was found to obey first kinetics with respect to the concentration of catalyst.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.463-468
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• 2002

This study investigates the variations of shear force, displacement, and fracture surface with the shear speed and the number of reflows. The experimental data of shear tests indicate that the shear force increases as increasing the number of reflows and the shear speed due to the formation of a kind of intermetallic compound, Ni$_3$Sn$_4$, on Au/Ni/Cu pad, and the work-hardening. However, general trends show that the shear force decreases due to increasing the thickness of the intermetallic compound over 4x reflow. It is observed that the intermetallic compound which is formed between solder and pad increases according to increasing the number of reflows, and the growth rate of the intermetallic compound at central region on the interface is faster than one at edge part. The general tendencies of shear force and displacement with different shear speeds are almost identical as an increase of the number of reflows.

• 혜화의학회지
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• 제20권1호
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• pp.153-160
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• 2011

Objective : The objective of this study is to observe the effect of Pharmacopuncture of Anti-inflammatory Herbal compound(AiC) theraphy on elbow pain Methods : The patients diagnosed as lateral epicondylitis and treated mainly with Anti-inflammatory Herbal compound(AiC). After the application of herbal acupuncture, The NRS and ROM of elbow were assessed. Results & conclusion : Symptoms of the patient such as elbow pain and dysfunction were improved after above treatments. so, it is suggested that oriental medical treatment(Pharmacopuncture of Anti-inflammatory Herbal compound(AiC)) is effective on Tennis elbow.

• 약학회지
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• 제41권2호
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• pp.268-272
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• 1997

We studied the action of methyleugenol on immediate hypersensitivity. Methyleugenol completely inhibited systemic anaphylaxis induced by compound 48/80 in mice. Methyleugenol al so inhibited local anaphylaxis induced by anti-dinitrophenyl (DNP) IgE. Moreover, methyleugenol dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80 or anti-DNP IgE. These results suggest that the inhibitory effect of methyleugenol on anaphylaxis induced by compound 48/80 or anti-DNP IgE is due to, in part at least, the membrane stabilization of mast cells.

• Journal of Applied Biological Chemistry
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• 제42권4호
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• pp.197-201
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• 1999

Antagonistic bacteria active against phytopathogenic fungi, Phytophthora capsici, Pythium ultimum, Rhizoctonia solani, Botrytis cinerea, and Fusarium oxysporum were isolated from greenhouse soils. An antifungal compound was extracted by ethyl acetate from acidified culture filtrate and purified through column chromatography and thin layer chromatography. Activity-guided bioassay was followed throughout the purification steps using Pythium ultimum as a test organism. The purified antifungal compound was identified as phenylacetic acid (PAA) based on the data obtained from IR, EI/MS, $^1H-NMR$, and $^{13}C-NMR$. Two different isolates, which had vast differences in differential characteristics except 16S rDNA sequence homology, produced the same compound, phenylacetic acid. $ED_{50}$ values of the phenylacetic acid against P. ultimum, P. capsici, R. solani, B. cinerea, and F. oxysporum were 45, 21, 318, 360, and 226 ppm, respectively.

• Journal of Microbiology and Biotechnology
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• 제25권8호
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• pp.1257-1264
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• 2015

Trichoderma strain T-33 has been demonstrated to have inhibitory effect on the fungus species Cytospora chrysosperma. Here, an active antifungal compound was obtained from Trichoderma strain T-33 extract via combined separation technologies, including organic solvent extraction, liquid chromatography, and thin-layer chromatography. The purified compound was further characterized by advanced analytical technologies to elucidate its chemical structure. Results indicated that the active antifungal compound in Trichoderma strain T-33 extract is 2,5-cyclohexadiene-1,4-dione-2,6-bis (1,1-dimethylethyl).

• Archives of Pharmacal Research
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• 제8권3호
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• pp.139-147
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• 1985

Americal A from the seeds of Phytolacca americana, was investigated for the antiinflammatory activity. The compound significantly inhibited edema induction, granuloma formation, arthritis induction and leucocyte emigration in CMC-pouch. But its anticarrageenin activity was not exhibited in adrenalectomized rats. These findings together with decrease in the contents of ascorbic acid and cholesterol in adrenals by administration of the compound suggest that its activity is mediated through stimulation of the pituitary-adrenal axis. The acute toxicity of the compound is very weak and gastric ulceration was not produced by the compound.