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Effects of Chronic Chitosan Salt Supplementation on Blood Pressure, Plasma Component, and Lipid Profile in Healthy Male and Female Adults

  • Kim, Hag-Lyeol;Son, Yeon-Hee;Kim, Seon-Jae;Kim, Du-Woon;Ma, Seung-Jin;Cho, Geon-Sik;Kim, In-Cheol;Ham, Kyung-Sik
    • Food Science and Biotechnology
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    • v.16 no.2
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    • pp.249-254
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    • 2007
  • The effects of chronic chitosan salt supplementation on the systolic (SBP) and diastolic blood pressure (DBP), and physiological parameters were investigated in healthy male and female adult. Chitosan salt was conducted by measuring various health-related factors such as body composition, plasma $Na^+$, $Cl^-$, lipid, and lipoproteins profiles, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) activity. Chitosan salt supplementation no significant differences before and after supplement in body composition variables and in SBP and DBP in either male or female. Plasma sodium and chlorine concentration no significant changes during chitosan salt supplementation, and no significant difference between two genders. Plasma GOT and GPT activity no different before and after supplement in either male or female. GOT activity significantly higher for male before supplement (p<0.05), and 2 weeks after supplement (p<0.01). The lipid and lipoproteins profiles of plasma no significant changes during chitosan salt supplementation in either male or female subjects. In summary, the chronic intake of chitosan salt did not affect the SBP or DBP, and posed no health risks.

Ginsenoside profiles and related gene expression during foliation in Panax ginseng Meyer

  • Kim, Yu-Jin;Jeon, Ji-Na;Jang, Moon-Gi;Oh, Ji Yeon;Kwon, Woo-Saeng;Jung, Seok-Kyu;Yang, Deok-Chun
    • Journal of Ginseng Research
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    • v.38 no.1
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    • pp.66-72
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    • 2014
  • Panax ginseng is one of the most important medicinal plants in Asia. Triterpene saponins, known as ginsenosides, are the major pharmacological compounds in P. ginseng. The present study was conducted to evaluate the changes in ginsenoside composition according to the foliation stage of P. ginseng cultured in a hydroponic system. Among the three tested growth stages (closed, intermediate, and opened), the highest amount of total ginsenoside in the main and fine roots was in the intermediate stage. In the leaves, the highest amount of total ginsenoside was in the opened stage. The total ginsenoside content of the ginseng leaf was markedly increased in the transition from the closed to intermediate stage, and increased more slowly from the intermediate to opened leaf stage, suggesting active biosynthesis of ginsenosides in the leaf. Conversely, the total ginsenoside content of the main and fine roots decreased from the intermediate to opened leaf stage. This suggests movement of ginsenosides during foliation from the root to the leaf, or vice versa. The difference in the composition of ginsenosides between the leaf and root in each stage of foliation suggests that the ginsenoside profile is affected by foliation stage, and this profile differs in each organ of the plant. These results suggest that protopanaxadiol- and protopanaxatriol(PPT)-type ginsenosides are produced according to growth stage to meet different needs in the growth and defense of ginseng. The higher content of PPT-type ginsenosides in leaves could be related to the positive correlation between light and PPT-type ginsenosides.

Changes in the Nutrition Status of Elderly Females in Health Promotion Programs of Health Centers in Chungbuk Province (충북 일부지역 보건소 건강증진프로그램에 참여한 여자 노인의 영양상태 변화)

  • Kim, Myoung-Sook
    • The Korean Journal of Community Living Science
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    • v.26 no.2
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    • pp.225-236
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    • 2015
  • Materials for nutrition education to promote nutrition intake and prevent diseases in elderly individuals were developed, nutrition education was provided to 46 elderly females for 12 weeks, and its effects on the body composition, blood profile, and nutritional quality of subjects were qualitatively analyzed. After the education program, the weight of subjects decreased from 56.7 kg to 56.0 kg (p<0.001), their body fat dropped from 20.8 kg to 19.6 kg (p<0.01), their body mass index (BMI) declined from $25.2kg/m^2$ to $24.9kg/m^2$ (p<0.01), and their percentage of body fat decreased significantly (p<0.05). On the other hand, blood sugar showed a significant increase from 131.6 mg/dl to 141.8 mg/dl (p<0.05). Overall, the percentage of nutrition intake rose. In particular, the estimated energy requirement increased from 89.3% to 99.5% (p<0.05). Further, the contrast ratio of recommended intake showed significant increases in protein (p<0.01), phosphorus (p<0.05), vitamin $B_2$ (p<0.05), vitamin $B_6$ (p<0.05), and niacin(p<0.001), and that of adequate intake showed a significant increase in sodium (p<0.05). The nutrient adequacy ratio (NAR) showed a significant increase only in niacin (p<0.05), and the index of nutritional quality (INQ) showed significant increases in protein (p<0.05) and niacin (p<0.001). After the nutrition education program, a qualitative analysis of nutrients consumed by subjects was conducted. The results show improvements across the board except for the deficient intake of calcium and folic acid, suggesting that the nutrition status of subjects changed in a positive direction through the program. The implementation of this program for elderly individuals in a continuous and repetitive manner is expected to facilitate their nutrition management.

Chemical Composition of PM2.5 and PM10 and Associated Polycyclic Aromatic Hydrocarbons at a Roadside and an Urban Background Area in Saitama, Japan

  • Naser, TarekMohamed;Yoshimura, Yuji;Sekiguchi, Kazuhiko;Wang, Qingyue;Sakamoto, Kazuhiko
    • Asian Journal of Atmospheric Environment
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    • v.2 no.2
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    • pp.90-101
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    • 2008
  • The chemical compositions of $PM_{2.5}$ and $PM_{10}$ and associated high-molecular-weight polycyclic aromatic hydrocarbons (PAHs) were investigated during winter and summer at a roadside and an urban background site in Saitama, Japan. The average concentrations of $PM_{2.5}$ exceeded the United States Environmental Protection Agency standards during both periods. Carbonaceous components were abundant in both the observed and calculated (by means of a mass closure model) chemical composition of $PM_{2.5}$. Traffic-related pollutants (elemental carbon and high-molecular-weight PAHs) were strongly associated with $PM_{2.5}$ rather than with larger particles. The mass concentrations of $PM_{2.5}$, as well as those of EC and PAHs associated with the particles, at the two sites were strongly correlated. Comparison of our data with source profile ratios indicates that diesel-powered vehicles were probably the main source of the measured PAHs. The PAHs concentrations were affected by meteorological conditions during our study. Our results highlight the need for the establishment of standards for $PM_{2.5}$ in Japan.

Effects of Solvent Fractions of Korean Cabbage Kimchi on Antioxidative Enzyme Activities and Fatty Acid Composition of Phospholipid of Rabbit Fed 1% Cholesterol Diet (배추김치 용매획분이 고 콜레스테롤 식이를 섭취한 토끼의 항산화 효소계 및 인지질 지방산 조성에 미치는 영향)

  • 김현주;권명자;송영옥
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.5
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    • pp.900-907
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    • 2000
  • The antioxidant effects of dichloromethane, ethylacetate or water fraction of kimchi added to the 1% cholesterol diet were studied. Six New Zealand white rabbits in each group were fed either control diet (basal diet containing 1% cholesterol) or experimental diet containing dichloromethane (CH$_2$Cl$_2$), ethylacetate (EtOAc) or water ($H_2O$) fraction of kimchi in the control diet for 16 weeks. The amount of each solvent fraction of kimchi added to the experimental diet was equivalent to 5% of freeze-dried kimchi. Levels of hepatic lipid oxidation expressed as TBARS or peroxide value for the experimental groups were lower than that of control (p<0.05). Liver homogenated of the experimental group containing dichloromethane fraction of kimchi inhibited LDL oxidation in the presence of Cu++ by 46% (p<0.05). The activities of catalase, Glutathione peroxidase (GSH-Px), Cu, Zn-superoxide (Cu, Zn-SOD) and Mn-superoxide (Mn-SOD) of experimental groups were lower than those of control group. Low enzyme activities observed from the kimchi solvent fraction groups might be due to the level of lipid oxidation progressed less in these groups. The most significant antioxidant effects were observed from dichloromethane fraction of kimchi among the experimental groups. The major fatty acids of hepatic phospholipid of rabbit were C18:2 and C18:0. But the major fatty acid profile was changed into C16:0, C18:0, C18:1, and C18:2 when rabbit was fed 1% cholesterol diet for 16 weeks, and this profile was almost the same as in rabbit fed diet containing kimchi solvent fraction. The ratio for unsaturated fatty acid to saturated fatty acid decreased by cholesterol induced diet and it was not corrected by kimchi solvent fractions.

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Effects of Combination Therapy with Anti-Obesity Herbal Medicine Including Ephedra Herba and Lorcaserin in Obese Patients: Two Case Reports (마황이 포함된 한방비만 처방과 Lorcaserin 병용 투여 후 호전된 비만 환자 치험 2예)

  • Kim, Min-Jee;Choi, Han Seok;Kim, Hojun
    • Journal of Korean Medicine for Obesity Research
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    • v.19 no.1
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    • pp.79-87
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    • 2019
  • Although there has been many studies about the co-administration of herb formula and western medicine, there is none about obesity. The aim of this study was to report the effects of co-administration of herb formula containing ephedra sinica and lorcaserin on two obese patients for about 2~4 months. During the treatment, we checked body weight and body composition, and collected blood samples to evaluate liver, kidney, thyroid function and lipid profile. This treatment not only decreased body weight but also improved body composition and lipid profile in both patients. There was no hepatic or renal toxicity, nor any serious side effects of treatment. This study demonstrated that co-administration of herb formula containing ephedra sinica and lorcaserin is a safe and effective therapy to lose weight and improve metabolic parameters for obese patients. Further large-scale clinical trials are needed to evaluate the anti-obesity effect of the combination of herbal and western medicines.

Rheological Properties and Fatty Acid Profile of Farm Butter Made from Cows' Milk Grazing on Mountain Pasture (산지 초지 방목우의 우유로 제조한 목장 버터의 조직 특성 및 지방산 조성)

  • Park, Seung-Young;Lee, Bae-Hun;Gang, Hyo-Jin;Kim, Gur-Yoo
    • Journal of Dairy Science and Biotechnology
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    • v.36 no.4
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    • pp.196-207
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    • 2018
  • This study was carried out to investigate the rheological properties and composition of unsaturated fatty acid of farm butter made from the milk of cows grazing at high mountain pasture in Pyronogchang SKY ranch (above sea level, 935 m). From two groups containing 7 cows each, a group was fed in-door with TMR (total mixed ration) feed and whereas the other group was grazed pastures for 12 h. The daily intake of feed on basis of dry matter (DMI), milk yields, concentration of milk constituents, and fatty acid profile of pasture milk were compared with control TMR milk. In addition, the physiochemical properties and composition of unsaturated fatty acids of the butter were also compared with those of the butter made from control TMR milk. Upon comparison, the health-promoting index (HPI) of fatty acids; the ratio of omega-6 fatty acids to omega-3 fatty acids (n-6 to n-3 UFA), the atherogenicity index (AI), and the ratio of linoleic acid to ${\alpha}$-linolenic acid (LA to ALA) was apparently improved in farm butter than those of control butter. Thus, it could make the dairy farm visitors to consume the farm butter containing the health-promoting fatty acids from the milk of cows grazing on mountain pasture.

Quality Characteristics and Composition of the Longissimus Muscle from Entire and Castrate Elk in Korea

  • Kim, Sang-Woo;Kim, Kwan-Woo;Park, Seong-Bok;Kim, Myung-Jick;Yim, Dong-Gyun
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.5
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    • pp.709-715
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    • 2016
  • The objective of the research was to determine the chemical composition as well as the physicochemical properties of the longissimus muscle from Korean entire and castrate elk. Twelve elk stags were raised and fed on concentrate with ad libitum hay. All animals were equally divided into castrated and non-castrated (entire) males, and slaughtered at 5 year of age. It was found that entire elk, in comparison with castrate elk, had higher content of moisture and lower content of fat (p<0.05). Compared with entire males, the castrates had lower pH and shear force values (p<0.05). However, castrates had higher $L^*$, $a^*$, and $b^*$ values compared with entires (p<0.05). An analysis of the fatty acid profile revealed that the muscles of entire and castrate elk had the most abundant concentrations of the following fatty acids: palmitic acid (C16:0) of the saturated fatty acid, and oleic acid (C18:1n-9) of the unsaturated fatty acid. The entire elk contains higher proportions of linoleic acid (C18:3n6), eicosenoic acid (C20:1n9), and arachidonic acid (C20:4n6) (p<0.05). Cholesterol content in elk was not affected by castration. The predominant free amino acid was glutamic acid related to umami taste. It is apparent that the castrate animals carried higher content of histidine, isoleucine, and leucine than those of the entire group (p<0.05). In this study, it was concluded that venison quality of elk is affected by castration and these results can provide fundamental information for venison production.

Effects of nitrogen sources on cell growth and biochemical composition of marine chlorophyte Tetraselmis sp. for lipid production

  • Kim, Garam;Mujtaba, Ghulam;Lee, Kisay
    • ALGAE
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    • v.31 no.3
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    • pp.257-266
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    • 2016
  • Nitrogen is one of the most critical nutrients affecting cell growth and biochemical composition of microalgae, ultimately determining the lipid or carbohydrate productivity for biofuels. In order to investigate the effect of nitrogen sources on the cell growth and biochemical composition of the marine microalga Tetraselmis sp., nine different N sources, including NaNO3, KNO3, NH4NO3, NH4HCO3, NH4Cl, CH3COONH4, urea, glycine, and yeast extract were compared at the given concentration of 8.82 mM. Higher biomass concentration was achieved under organic nitrogen sources, such as yeast extract (2.23 g L−1) and glycine (1.62 g L−1), compared to nitrate- (1.45 g L−1) or ammonium-N (0.98 g L−1). All ammonium sources showed an inhibition of cell growth, but accumulated higher lipids, showing a maximum content of 28.3% in ammonium bicarbonate. When Tetraselmis sp. was cultivated using yeast extract, the highest lipid productivity of 36.0 mg L−1 d−1 was achieved, followed by glycine 21.5 mg L−1 d−1 and nitrate 19.9 mg L−1 d−1. Ammonium bicarbonate resulted in the lowest lipid productivity of 14.4 mg L−1 d−1. The major fatty acids in Tetraselmis sp. were palmitic, oleic, linoleic and linolenic acids, regardless of the nutritional compositions, indicating the suitability of this species for biodiesel production.

Effects of Two Herbal Extracts and Virginiamycin Supplementation on Growth Performance, Intestinal Microflora Population and Fatty Acid Composition in Broiler Chickens

  • Ramiah, Suriya Kumari;Zulkifli, Idrus;Rahim, Nordiana Asyikin Abdul;Ebrahimi, Mahdi;Meng, Goh Yong
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.375-382
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    • 2014
  • The competency of garlic and pennywort to improve broiler chicken growth and influence intestinal microbial communities and fatty acid composition of breast meat were studied. Two hundred forty, "day-old" chicks were randomly allocated to 4 treatment groups consisting of 6 replications of 10 chicks in each pen. The groups were assigned to receive treatment diets as follows: i) basal diet (control), ii) basal diet plus 0.5% garlic powder (GP), iii) basal diet plus 0.5% pennywort powder (PW) and iv) 0.002% virginiamycin (VM). Birds were killed at day 42 and intestinal samples were collected to assess for Lactobacillus and Escherichia coli. The pectoralis profundus from chicken breast samples was obtained from 10 birds from each treatment group on day 42 and frozen at $-20^{\circ}C$ for further analyses. Fatty acid profile of breast muscles was determined using gas liquid chromatography. Feed intake and weight gain of broilers fed with GP, PW, and VM were significantly higher (p<0.05) compared to control. Feeding chicks GP, PW, and VM significantly reduced Escherichia coli count (p<0.05) while Lactobacillus spp count were significantly higher (p<0.05) in the gut when compared to control group on day 42. Supplemented diet containing pennywort increased the C18:3n-3 fatty acid composition of chickens' breast muscle. Garlic and pennywort may be useful in modulating broiler guts as they control the enteropathogens that help to utilize feed efficiently. This subsequently enhances the growth performances of broiler chickens.