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Effects of Chronic Chitosan Salt Supplementation on Blood Pressure, Plasma Component, and Lipid Profile in Healthy Male and Female Adults  

Kim, Hag-Lyeol (Department of Food Science and Technology, Food Industrial Technology Research Center, Mokpo National University)
Son, Yeon-Hee (Solar Salt Biotechnology Research Center, Mokpo National University)
Kim, Seon-Jae (Division of Food Technology and Nutrition, Jeonnam National University)
Kim, Du-Woon (Division of Food Technology and Nutrition, Jeonnam National University)
Ma, Seung-Jin (Department of Food Science and Technology, Food Industrial Technology Research Center, Mokpo National University)
Cho, Geon-Sik (Biotech Company)
Kim, In-Cheol (Department of Food Science and Technology, Food Industrial Technology Research Center, Mokpo National University)
Ham, Kyung-Sik (Department of Food Science and Technology, Food Industrial Technology Research Center, Mokpo National University)
Publication Information
Food Science and Biotechnology / v.16, no.2, 2007 , pp. 249-254 More about this Journal
Abstract
The effects of chronic chitosan salt supplementation on the systolic (SBP) and diastolic blood pressure (DBP), and physiological parameters were investigated in healthy male and female adult. Chitosan salt was conducted by measuring various health-related factors such as body composition, plasma $Na^+$, $Cl^-$, lipid, and lipoproteins profiles, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) activity. Chitosan salt supplementation no significant differences before and after supplement in body composition variables and in SBP and DBP in either male or female. Plasma sodium and chlorine concentration no significant changes during chitosan salt supplementation, and no significant difference between two genders. Plasma GOT and GPT activity no different before and after supplement in either male or female. GOT activity significantly higher for male before supplement (p<0.05), and 2 weeks after supplement (p<0.01). The lipid and lipoproteins profiles of plasma no significant changes during chitosan salt supplementation in either male or female subjects. In summary, the chronic intake of chitosan salt did not affect the SBP or DBP, and posed no health risks.
Keywords
chronic chitosan salt supplementation; blood pressure; plasma component; lipid profile;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By Web Of Science : 3  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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1 Weinberger HM, Fineberg NS. Sodium and volumen sensitivity of blood pressure: Age and pressure change over time. Hypertension 18: 67-71 (1991)   DOI
2 Jeon YJ, Lee UH, Kim SK. Bioactivities of chitin and chitosan (I). J. Chitin Chitosan 1: 4-13 (1996)
3 Mahan LK, Arlin MT. Food Nutrition and Diet Therapy. W.B. Saunders Co., PA, USA. p. 387 (1992)
4 Ryu HI, Bang JH, Kim YH. Clinical study of body safety in bamboo salt. Final Reports on Bamboo Salt, University of Yeungnam, Gyeongbuk, Korea (2001)
5 Joongang Joins. Com. Health and salt. www.joongang.co.kr. Accessed Feb. 10, 2004. (2004)
6 Blackwood AM, Sagnella GA, Cook DG, Cappuccio FP. Urinary calcium excretion, sodium intake, and blood pressure in a multiethnic population: Results of the Wandsworth heart and stroke study. J. Hum. Hypertens. 15: 229-238 (2001)   DOI
7 Oh JY, Kim YS, Shin DH. Changes in microorganisms, enzyme activities, and gas formation by the addition of mustard powder on kochujang with different salt concentration. Food Sci. Biotechnol. 15: 298-302 (2006)   과학기술학회마을
8 Bayorh MA, Socci RR, Eatman D, Wang M, Thierry-Palmer M. The role of gender in salt-induced hypertension. Clin. Exp. Hypertens. 23: 241-248 (2001)   DOI   ScienceOn
9 Kurtz TW, Morris RW. Dietary chloride as a determinant disordered calcium metabolism in salt-dependant hypertension. Life Science 36: 921-929 (1987)
10 Kim HL, Son YH, Moon SM, Gao CS, Ham KS. Effect of acute chitosan supplement in middle aged male and female (abstract no. P7-11). In: Abstracts: 2004 Annual Meeting and International Symposium. November 17-19, Ramada Plaza Jeju Hotel. The Korean Society of Food Science and Nutrition. Seoul, Korea (2004)
11 Ray PE, Suga SI, Liu XH, Huang X, Johnson RJ. Chronic potassium depletion induces renal injury, salt sensitivity, and hypertension in young rats. Kidney Int. 59: 1850-1862 (2001)   DOI   ScienceOn
12 Kato H, Hiromichi O. Effects of salt in hypertensive rats. J. Traditional Med. 11: 198-205 (1994)
13 Bragulat EA, Sierra de Ia, Antonio MT, Coca A. Endothelial dysfunction in salt-sensitive essential hypertension. Hypertension 37: 444-452 (2001)   DOI   ScienceOn
14 Fox SI. Physiology of kidney. Vol. 17, pp. 405-410. In: Human Physiology. McGraw-Hill Korea, Inc., Life Science Publishing Co., Seoul, Korea (2003)
15 National Research Council. Diet and Health: Implication for Reducing Chronic Disease Risk. National Academy Press, Washington, DC, USA. pp. 55-58 (1989)
16 Moo JH, Yoon MY, Cha GS, Byun MW, Hwang HJ. Influence of curing and heating on formation of N-nitrosamines from biogenic amines in food model system using Korean traditional fermented fish product. Food Sci. Biotechnol. 14: 168-170 (2005)
17 Park KY. The nutritional evaluation, and antimutagenic and anticancer effects of kimchi. J. Korean Soc. Food Nutr. 24: 169-182 (1995)   과학기술학회마을
18 Grundy SM. Cholesterol and coronary heart disease. J. Am. Med. Assoc. 256: 2849-2854 (1986)   DOI
19 Cheng ZJ, Vaskonen T, Tikkanden I, Nurminen K, Ruskoaho H, Vapaatalo H, Muller D, Park J, Luft FC, Mervaala EMA. Endothelial dysfunction in salt-sensitive hypertension in spontaneously diabetic Goto-Kaizaki rats. Hypertension 37: 433-442 (2001)   DOI   ScienceOn
20 National Heart, Lung, and Blood Institute. The 5th Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. NIH Publication 9: 1088-1091 (1993)
21 Kim GY, Jung JH, Kim SK, Cho JE, Lee JM. The effects of endurance exercise and chitosan salt on blood pressure in normotensive rats. Korean J. Exer. Nutr. 8: 199-206 (2004)
22 Tannen DH. Effects of potassium on blood pressure control. Ann. Int. Med. 98: 1850-1856 (1983)
23 Beerak Lab Processing 2 Team. Reports of Salt. Beerak Lab Co., Kirnhae, Korea (1995)