• Title/Summary/Keyword: complex segment

Search Result 167, Processing Time 0.025 seconds

Virtual Surgical Planning and Stereolithography-guided Osteotomy for 3 Dimensional Mandibular Reconstruction with Free Fibula Osseous Flaps: A Case Report (비골을 이용한 3차원적 하악골 재건 시 가상모의수술 및 입체조형기법을 이용한 골절단 가이드의 활용: 증례보고)

  • Nam, Woong;Makhoul, Nicholas;Ward, Brent;Helman, Joseph I.;Edwards, Sean
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.34 no.5
    • /
    • pp.337-342
    • /
    • 2012
  • The osseous or osteocutaneous free fibula flap has become the gold standard for most mandibular reconstructions because of its favorable osseous characteristics. However, disadvantages, such as the time-consuming reconstructive step, difficulty in performing the osteotomies to precisely recreate the shape of the missing segment of mandible and poor bone-to-bone contact play a role in making the surgeons look for alternative flaps. With the advent of computerized design software, which accurately plans complex 3-dimensional reconstructions, has become a process that is more efficient and precise. However, the ability to transfer the computerized plan into the surgical field with stereolithographic models and guides has been a significant development in advancing reconstruction in the maxillofacial regions. The ability to "pre-plan" the case, mirror and superimpose natural structures into diseased and deformed areas, as well as the ability to reproduce these plans with good surgical precision has decreased overall operative time, and has helped facilitate functional and esthetic reconstruction. We describe a complex case treated with this technique, showing the power and elegance of computer assisted maxillofacial reconstruction from the University of Michigan, Oral and Maxillofacial Surgery.

Molecular Cloning of the Sec61p ${\gamma}$ Subunit Homologue Gene from the Mole Cricket, Gryllotalpa orientalis

  • Kim, Iksoo;Lee, Kwang-Sik;Jin, Byung-Rae;Kim, Eun-Sun;Lee, Heui-Sam;Ahn, Mi-Young;Sohn, Hung-Dae;Ryu, Kang-Sun
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • v.5 no.1
    • /
    • pp.73-77
    • /
    • 2002
  • The Sec61 trimeric complex ($\alpha$,$\beta$, and ${\gamma}$ subunits) is one of the Sec-complex responsible for post-translational protein translocation across the endoplasmic reticulum membrane in diverse organisms. In this study, a cDNA encoding the Sec61p ${\gamma}$ subunit homologue was isolated from the cDNA library of the mole cricket, Gryllotalpa orientalis. Sequence analysis of a 442-bp cDNA clone showed it to contain an open reading frame of 68 amino acid residues consisted of 204-bp. The homologues of the gene were found in the GenBank database in a diverse organism including insect, mammals, fungi, and plants. The deduced amino acid sequence of Sec61p ${\gamma}$ subunit homologue of the mole cricket showed the highest homology to the gene of the singly known insect, Drosophila melanogester (93% identity), and the least homology to that of the baker's yeast, Saccharomyces cerevisiae (37.2%). Phylogenetic analysis also confirmed a close relationship between the insect Sec61p ${\gamma}$ subunit homologues of G. orientalis and D. melanogester. Hydropathy analysis of the cricket mole and published other data suggested that the hydrophobic segment close to C-terminus is predicted to be the putative membrane anchor, Multiple alignment of the Sec61p ${\gamma}$ subunit homologue among several organisms showed the presence of several conserved domains including the conserved proline at position 28.

Experimental Studies on Induced Traumatic Pericarditis and Myocarditis in Ruminants (반추수(反芻獸)의 창상성심낭심근염(創傷性心囊心筋炎)에 관(關)한 실험적연구(實驗的硏究))

  • Cheong, C.K.;Nam, T.C.;Seung, J.K.;Oak, J.W.
    • Korean Journal of Veterinary Research
    • /
    • v.20 no.2
    • /
    • pp.127-134
    • /
    • 1980
  • This study was performed to obtain an accurate methods of diagnosis in early stage of traumatic pericarditis and myocarditis in ruminants. Korean native goats were used as experimental animal and traumatic pericarditis and myocarditis were induced by surgical intervention. The changes in clinical signs, hematological values, blood enzymes and electrocardigrams were observed for 14 days after operation. The results obtained were as follows: 1. Body temperature in experimental group of induced traumatic pericarditis and myocarditis was slightly increased than control group that was rumenotomized. Heart rate was increased in both groups but the increased rate was noticed remarkably in experimental group. There was no change in respiratory rate in experimental and control group. 2. Total leucocytes counts and neutrophil percentage maintained higher level after operation and lymphocytes percentage noticed reversed proportion to neutrophil in both groups. 3. Serum total protein concentration and alkaline phosphatase activities after operation showed a little lower levels than these values prior to operation. Serum glutamic oxaloacetic transaminase and lactic dehydrogenase activities in control group showed slight increase through all the experimental period, while in experimental group these activities were markedly elevated and an increase in serum lactic dehydrogenase activities was more remarkable comparing to serum glutamic oxaloacetic transaminase. 4. Electrocardiograms in control group did not show any abnormalities except for slight increase in heart rate. In experimental group the amplitude of QRS complex was increased in duration of experimental period. The transference from QRS complex to T wave was uncertain and S-T segment moved upward obliquely through electrical zero line.

  • PDF

Touching Pigs Segmentation and Tracking Verification Using Motion Information (움직임 정보를 이용한 근접 돼지 분리와 추적 검증)

  • Park, Changhyun;Sa, Jaewon;Kim, Heegon;Chung, Yongwha;Park, Daihee;Kim, Hakjae
    • KIPS Transactions on Software and Data Engineering
    • /
    • v.7 no.4
    • /
    • pp.135-144
    • /
    • 2018
  • The domestic pigsty environment is highly vulnerable to the spread of respiratory diseases such as foot-and-mouth disease because of the small space. In order to manage this issue, a variety of studies have been conducted to automatically analyze behavior of individual pigs in a pig pen through a video surveillance system using a camera. Even though it is required to correctly segment touching pigs for tracking each pig in complex situations such as aggressive behavior, detecting the correct boundaries among touching pigs using Kinect's depth information of lower accuracy is a challenging issue. In this paper, we propose a segmentation method using motion information of the touching pigs. In addition, our proposed method can be applied for detecting tracking errors in case of tracking individual pigs in the complex environment. In the experimental results, we confirmed that the touching pigs in a pig farm were separated with the accuracy of 86%, and also confirmed that the tracking errors were detected accurately.

Posttranscriptional and posttranslational determinants of cyclooxygenase expression

  • Mbonye, Uri R.;Song, In-Seok
    • BMB Reports
    • /
    • v.42 no.9
    • /
    • pp.552-560
    • /
    • 2009
  • Cyclooxygenases (COX-1 and COX-2) are ER-resident proteins that catalyze the committed step in prostanoid synthesis. COX-1 is constitutively expressed in many mammalian cells, whereas COX-2 is usually expressed inducibly and transiently. Abnormal expression of COX-2 has been implicated in the pathogenesis of chronic inflammation and various cancers; therefore, it is subject to tight and complex regulation. Differences in regulation of the COX enzymes at the posttranscriptional and posttranslational levels also contribute significantly to their distinct patterns of expression. Rapid degradation of COX-2 mRNA has been attributed to AU-rich elements (AREs) at its 3’UTR. Recently, microRNAs that can selectively repress COX-2 protein synthesis have been identified. The mature forms of these COX proteins are very similar in structure except that COX-2 has a unique 19-amino acid (19-aa) segment located near the C-terminus. This C-terminal 19-aa cassette plays an important role in mediation of the entry of COX-2 into the ER-associated degradation (ERAD) system, which transports ER proteins to the cytoplasm for degradation by the 26S proteasome. A second pathway for COX-2 protein degradation is initiated after the enzyme undergoes suicide inactivation following cyclooxygenase catalysis. Here, we discuss these molecular determinants of COX-2 expression in detail.

Proposing Shape Alignment for an Improved Active Shape Model (ASM의 성능향상을 위한 형태 정렬 방식 제안)

  • Hahn, Hee-Il
    • Journal of Korea Multimedia Society
    • /
    • v.15 no.1
    • /
    • pp.63-70
    • /
    • 2012
  • In this paper an extension to an original active shape model(ASM) for facial feature extraction is presented. The original ASM suffers from poor shape alignment by aligning the shape model to a new instant of the object in a given image using a simple similarity transformation. It exploits only informations such as scale, rotation and shift in horizontal and vertical directions, which does not cope effectively with the complex pose variation. To solve the problem, new shape alignment with 6 degrees of freedom is derived, which corresponds to an affine transformation. Another extension is to speed up the calculation of the Mahalanobis distance for 2-D profiles by trimming the profile covariance matrices. Extensive experiment is conducted with several images of varying poses to check the performance of the proposed method to segment the human faces.

Cyanide- and Phenoxo-Bridged Heterobimetallic Fe(III)-Mn(III) Coordination Polymer: Synthesis, Crystal Structures and Magnetic Properties

  • Zhang, Daopeng;Kong, Lingqian;Li, Yueyun;Wang, Ping;Chen, Xia
    • Bulletin of the Korean Chemical Society
    • /
    • v.35 no.9
    • /
    • pp.2684-2688
    • /
    • 2014
  • Two two-dimensional cyanide- and phenoxo-bridged heterometallic M(II)-Mn(III) (M = Ni, Pd) coordination polymers $\{[Mn(saltmen)]_4[Ni(CN)_4]\}(ClO_4)_2{\cdot}CH_3OH{\cdot}H_2O$ (1) and $\{[Mn(saltmen)]_4[Pd(CN)_4]\}(ClO_4)_2{\cdot}CH_3CN{\cdot}H_2O$ (2) ($saltmen^{2-}$ = N,N'-(1,1,2,2-tetramethylethylene)bis(salicylideneaminato)dianion) have been obtained by using $K_2[M(CN)_4]$ as building blocks and a salen-tpye Schiff-base manganese(III) compound as assembling segment. Single X-ray analysis reveals their isostrutural cyanide-bridged $MMn_4$ pentanuclear cationic structure. The four Schiff base manganese units of the pentanuclear entity are self-complementary through the phenoxo oxygen atoms from the neighboring complex, therefore forming cyanide- and phenoxo-bridged 2D sheet-like structure. Investigation over magnetic susceptibilities reveals the overall ferromagnetic coupling between the adjacent Mn(III) ions bridged by the phenoxo oxygen atoms with J = 2.13 and $2.21cm^{-1}$ for complexes 1 and 2, respectively.

A Study on Optical Condition and preprocessing for Input Image Improvement of Dented and Raised Characters of Tires (타이어 음,양각 문자의 입력영상 개선을 위한 전처리와 광학조건에 관한 연구)

  • 류한성;최중경;구본민;박무열;윤경섭
    • Proceedings of the IEEK Conference
    • /
    • 2001.06d
    • /
    • pp.93-96
    • /
    • 2001
  • In this paper, we present a vision algorithm and method for input image improvement and preprocessing of dented and raised characters on the sidewall of tires. we define optical condition between reflect coefficient and reflectance by the physical vector calculate. On the contrary this work will recognize the engraved characters using the computer vision technique. Tire input images have all most same grey levels between the characters and backgrounds. The reflectance is little from a tire surface. therefore, it's very difficult segment the characters from the background. Moreover, one side of the character string is raised and the other is dented. So, the captured images are varied with the angle of camera and illumination. For optimum input images, the angle between camera and illumination was found out to be with in 90。 .In addition, We used complex filtering with low-pass and high-pass band filters to improve input images, for clear input images. Finally we define equation reflect coefficient and reflectance. By doing this, we obtained good images of tires for pattern recognition.

  • PDF

Restoration of Sagittal Balance in Spinal Deformity Surgery

  • Makhni, Melvin C.;Shillingford, Jamal N.;Laratta, Joseph L.;Hyun, Seung-Jae;Kim, Yongjung J.
    • Journal of Korean Neurosurgical Society
    • /
    • v.61 no.2
    • /
    • pp.167-179
    • /
    • 2018
  • The prevalence of patients with adult spinal deformity (ASD) has been reported as high as 68%. ASD often leads to significant pain and disability. Recent emphasis has been placed on sagittal plane balance and restoring normal sagittal alignment with regards to the three dimensional deformity of ASD. Optimal sagittal alignment has been known to increase spinal biomechanical efficiency, reduce energy expenditure by maintaining a stable posture with improved load absorption, influence better bony union, and help to decelerate adjacent segment deterioration. Increasingly positive sagittal imbalance has been shown to correlate with poor functional outcome and poor self-image along with poor psychological function. Compensatory mechanisms attempt to maintain sagittal balance through pelvic rotation, alterations in lumbar lordosis as well as knee and ankle flexion at the cost of increased energy expenditure. Restoring normal spinopelvic alignment is paramount to the treatment of complex spinal deformity with sagittal imbalance. Posterior osteotomies including posterior column osteotomies, pedicle subtraction osteotomies, and posterior vertebral column resection, as well anterior column support are well known to improve sagittal alignment. Understanding of whole spinal alignment and dynamics of spinopelvic alignment is essential to restore sagittal balance while minimizing the risk of developing sagittal decompensation after surgical intervention.

Convolutional Neural Network based Audio Event Classification

  • Lim, Minkyu;Lee, Donghyun;Park, Hosung;Kang, Yoseb;Oh, Junseok;Park, Jeong-Sik;Jang, Gil-Jin;Kim, Ji-Hwan
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.12 no.6
    • /
    • pp.2748-2760
    • /
    • 2018
  • This paper proposes an audio event classification method based on convolutional neural networks (CNNs). CNN has great advantages of distinguishing complex shapes of image. Proposed system uses the features of audio sound as an input image of CNN. Mel scale filter bank features are extracted from each frame, then the features are concatenated over 40 consecutive frames and as a result, the concatenated frames are regarded as an input image. The output layer of CNN generates probabilities of audio event (e.g. dogs bark, siren, forest). The event probabilities for all images in an audio segment are accumulated, then the audio event having the highest accumulated probability is determined to be the classification result. This proposed method classified thirty audio events with the accuracy of 81.5% for the UrbanSound8K, BBC Sound FX, DCASE2016, and FREESOUND dataset.