• International Journal of Internet, Broadcasting and Communication
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• 제11권2호
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• pp.50-58
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• 2019

The clear and specific objective of this study is to design a false news discriminator algorithm for news articles transmitted on a text-based basis and an architecture that builds it into a system (H/W configuration with Hadoop-based in-memory technology, Deep Learning S/W design for bigdata and SNS linkage). Based on learning data on actual news, the government will submit advanced "fake news" test data as a result and complete theoretical research based on it. The need for research proposed by this study is social cost paid by rumors (including malicious comments) and rumors (written false news) due to the flood of fake news, false reports, rumors and stabbings, among other social challenges. In addition, fake news can distort normal communication channels, undermine human mutual trust, and reduce social capital at the same time. The final purpose of the study is to upgrade the study to a topic that is difficult to distinguish between false and exaggerated, fake and hypocrisy, sincere and false, fraud and error, truth and false.

• 한국문헌정보학회지
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• 제38권1호
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• pp.35-50
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• 2004

본 연구는 한글 OPAC에서 문헌의 분류와 브라우징에 적합한 정적 계층클러스터링 모형이 서명단어 탐색으로 검색된 탐색결과를 클러스터링하는데도 효과적인지를 규명하기 위해 수행되었다. 서명에 출현하는 단어와 색인자가 부여한 통제어를 통합한 색인어를 이진빈도로 가중치를 주어, 다이스와 자카드 계수, 집단 간 평균연결과 완전연결 클러스터링 기법이 테스트되었다. 16개의 서명단어 탐색으로 검색된 문헌을 클러스터링한 결과 최적으로 선택된 클러스터의 정확률은 유사도 계수나 클러스터링 기법에 관계없이 서명단어탐색보다 100％이상 향상되었다. 1단계와 최종단계 클러스터링 모두에서, 정확률 측면에서는 완전연결이, 재현을 측면에서는 집단 간 평균연결이 더 효과적이었으나 통계적으로 유의한 수준은 아니었다. 1단계 클러스터에서 집단 간 평균연결이 보다 높은 재현율을 보인 것은 유의하였다. 다이스와 자카드 사이에 차이는 없었다. 최종클러스터가 선택되기까지 집단 간 평균연결은 너무 긴 계층군집 단계를 필요로 하여 탐색효율 측면에서 바람직해 보이지 않았다.

• Asian-Australasian Journal of Animal Sciences
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• 제29권4호
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• pp.464-470
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• 2016

The objective of this study was to investigate the accuracy of imputation from low density (LDC) to moderate density SNP chips (MDC) in a Thai Holstein-Other multibreed dairy cattle population. Dairy cattle with complete pedigree information (n = 1,244) from 145 dairy farms were genotyped with GeneSeek GGP20K (n = 570), GGP26K (n = 540) and GGP80K (n = 134) chips. After checking for single nucleotide polymorphism (SNP) quality, 17,779 SNP markers in common between the GGP20K, GGP26K, and GGP80K were used to represent MDC. Animals were divided into two groups, a reference group (n = 912) and a test group (n = 332). The SNP markers chosen for the test group were those located in positions corresponding to GeneSeek GGP9K (n = 7,652). The LDC to MDC genotype imputation was carried out using three different software packages, namely Beagle 3.3 (population-based algorithm), FImpute 2.2 (combined family- and population-based algorithms) and Findhap 4 (combined family- and population-based algorithms). Imputation accuracies within and across chromosomes were calculated as ratios of correctly imputed SNP markers to overall imputed SNP markers. Imputation accuracy for the three software packages ranged from 76.79% to 93.94%. FImpute had higher imputation accuracy (93.94%) than Findhap (84.64%) and Beagle (76.79%). Imputation accuracies were similar and consistent across chromosomes for FImpute, but not for Findhap and Beagle. Most chromosomes that showed either high (73%) or low (80%) imputation accuracies were the same chromosomes that had above and below average linkage disequilibrium (LD; defined here as the correlation between pairs of adjacent SNP within chromosomes less than or equal to 1 Mb apart). Results indicated that FImpute was more suitable than Findhap and Beagle for genotype imputation in this Thai multibreed population. Perhaps additional increments in imputation accuracy could be achieved by increasing the completeness of pedigree information.

• Journal of Life Science
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• 제9권1호
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• pp.26-34
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• 1999

A thermostable pullulanase has been isolated and purified from Thermus caldophilus GK-24 to a homogeneity by gel-filtration and ion-exchange chromatography. The specific activity of the purified enzyme was 431-fold increase from the crude culture broth with a recovery of 11.4%. The purified enzyme showed $M_{r}$ of 65 kDa on denaturated and natural conditions. The pI of the enzyme was 6.1 and Schiff staining was negative, suggesting that the enzyme is not a glycoprotein. The enzyme was most active at pH 5.5. The activity was maximal at $75^{\cire}C$ and stable up to $95^{\cire}C$ for 30 min at pH 5.5. The enzyme was stable to incubation from pH 3.5 to pH 8.0 at $4^{\cire}C$ for 24hr. The presence of pullulan protected the enzyme from heat inactivation, the extent depending upon the substrate concentration. The activity of the enzyme was simulated by $Mn^{2+}$ ion, }$Ni^{2+}$, $Ca^{2+}$, $Co^{2+}$ ions. The enzyme hydrolyzed the ${\alpha}$-1,6-linkages of amylopectin, glycogens, ${\alpha}$, ${\beta}$-limited dextrin, and pullulan. The enzyme caused the complete hydrolysis of pullulan to maltotriose and the activity was inhibited by $\alpha$, $\beta$, or $\gamma$-cyclodextrins. The $NH_{2}$-terminal amino acid sequence [(Ala-Pro-Gln-(Asp of Tyr)-Asn-Leu-Leu-Xaa-ILe-Gly-Ala(Ser)] was compared with known sequences of various sources and that was compared with known sequences of various sources and that was different from those of bacterial and plant enzymes, suggesting that the enzymes are structurally different.

• 한국약용작물학회지
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• 제5권4호
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• pp.260-265
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• 1997

양적형질을 중심으로 다변량 해석법에 의해 택사 품종들간의 유연 관계를 추정하고 이에 기초한 cluster analysis를 실시하여 품종을 분류한 결과는 다음과 같다. Euclidian distance $(D^2)$에 의하여 공시한 62개 품종을 5개군으로 대별해 볼 수 있었는데 제1군이 12품종, 제2군이 21품종, 제3군이 17품종, 제4군이 5품종, 제5군이 7품종으로 군을 형성하였다. 제 1군은 건근중은 높고, 생근중이 낮으며 제2군은 생근중이 높고 제4군은 건근중이 낮은 품종군이었다. 지리적 분포와 유전적 변이는 직접적인 관련이 없었다. 품종군내, 품종군간의 $D^2$에 가장 크게 영향을 미친 형질은 경장과 생근중이었다.

• 한국자원식물학회지
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• 제27권1호
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• pp.89-94
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• 2014

양적 형질을 중심으로 다변량 분석법에 의해 매실 품종들 간의 유전적 거리를 추정하고 이에 기초한 클러스터 분석을 실시하여 품종을 분류하였다. Mahalanobis's distance (D)에 의하여 공시한 20개 품종을 5개 군으로 대별해 볼 수 있었는데, 제1군이 2품종, 제2군이 4품종, 제3군이 5품종, 제4군이 5품종, 제5군이 4품종으로 그룹을 형성하였다. 제1군과 제2군은 꽃잎 수와 암술 수가 많은 품종인 반면에 제3군과 제4군은 엽장과 엽폭은 높으나 꽃잎 수와 암술 수가 낮은 품종군이었다. 지리적 분포와 유전적 변이는 직접적인 관련이 없었다. 품종군 내, 품종 간의 $D^2$에 가장 크게 영향을 미친 형질은 암술 수와 엽장 및 엽폭이었다.

• Journal of Construction Engineering and Project Management
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• 제5권2호
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• pp.11-15
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• 2015

The Last PlannerSystem (LPS) has been implemented on construction projects to increase work flow reliability, a precondition for project performance againstproductivity and progress targets. The LPS encompasses four tiers of planning processes:master scheduling, phase scheduling, lookahead planning, and commitment / weeklywork planning. This research highlights deficiencies in the current implementation of LPS including poor lookahead planning which results in poor linkage between weeklywork plans and the master schedule. This poor linkage undetermines the ability of theweekly work planning process to select for execution tasks that are critical to projectsuccess. As a result, percent plan complete (PPC) becomes a weak indicator of project progress. The purpose of this research is to improve lookahead planning (the bridgebetween weekly work planning and master scheduling), improve PPC, and improve theselection of tasks that are critical to project success by increasing the link betweenShould, Can, Will, and Did (components of the LPS), thereby rendering PPC a betterindicator of project progress. The research employs the case study research method to describe deficiencies inthe current implementation of the LPS and suggest guidelines for a better application ofLPS in general and lookahead planning in particular. It then introduces an analyticalsimulation model to analyze the lookahead planning process. This is done by examining the impact on PPC of increasing two lookahead planning performance metrics: tasksanticipated (TA) and tasks made ready (TMR). Finally, the research investigates theimportance of the lookahead planning functions: identification and removal ofconstraints, task breakdown, and operations design.The research findings confirm the positive impact of improving lookaheadplanning (i.e., TA and TMR) on PPC. It also recognizes the need to perform lookaheadplanning differently for three types of work involving different levels of uncertainty:stable work, medium uncertainty work, and highly emergent work.The research confirms the LPS rules for practice and specifically the need to planin greater detail as time gets closer to performing the work. It highlights the role of LPSas a production system that incorporates deliberate planning (predetermined andoptimized) and situated planning (flexible and adaptive). Finally, the research presents recommendations for production planningimprovements in three areas: process related, (suggesting guidelines for practice),technical, (highlighting issues with current software programs and advocating theinclusion of collaborative planning capability), and organizational improvements(suggesting transitional steps when applying the LPS).

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2001년도 발생공학 국제심포지움 및 학술대회 발표자료집
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• pp.14-17
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• 2001

Positional clonging (map-based cloning) of mutations or genetic variations has been served as an invaluable tool to understand in-vivo functions of genes and to identify molecular components underlying phenotypes of interest. Mice homozygous for the cerebellar deficient folia (cdf) mutation are ataxic, with cerebellar hypoplasia and abnormal lobulation of the cerebellum. In the cdf mutant cerebellum approximately 40% of Purkinje cells are ectopically located within the white matter and the inner granule cell layer (IGL). To identify the cdf gene, a high-resolution genetic map for the cdf-gene-encompassing region was constructed using 1997 F2 mice generated from C3H/HeSnJ-cdf/cdf and CAST/Ei intercross. The cdf gene showed complete linkage disequilibrium with three tightly linked markers D6Mit208, D6Mit359, and D6Mit225. A contig using YAC, BAC, and P1 clones was constructed for the cdf critical region to identify the gene. A deletion in the cdf critical region on chromosome 6 that removes approximately 150 kb of DNA selection. cdf mutant mice with the transgenic copy of the identified gene restored the brain abnormalities of the mutant mice. The positional cloning of cdf gene provides a good example showing the identification of a gene could lead to finding a new component of important molecular pathways.

• 정보관리학회지
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• 제25권2호
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• pp.157-166
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• 2008

본 연구에서는 ASIST 프로시딩을 인용한 저널들을 중심으로 패스파인더 네트워크 분석을 수행함으로써, ASIST 프로시딩의 지식이 어떠한 주제영역을 중심으로 네트워크 구조를 형성하고 있는지를 확인하는 데에 그 목적이 있다. 이를 위하여 Scopus 데이터베이스에서 검색한 240개의 문헌을 대상으로 완전연결 클러스터링 기법을 통하여 16개 클러스터를 도출하였으며, MDS 및 패스파인더 네트워크 분석을 통하여 지식 네트워크를 매핑하였다. 지금까지 대부분의 경우 학술지를 대상으로 수행되어 온 네트워크 분석을 프로시딩을 대상으로 분석을 시도하였으며, 분석결과 ASIST 프로시딩은 정보추구행태 및 탐색과 인터페이스, 계량서지학 및 지식관리 주제영역의 논문이 타 문헌에 활발하게 소비되고 있음을 확인할 수 있었다.

• 정보기술과데이타베이스저널
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• 제8권1호
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• pp.1-11
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• 2001

More and more cyber shopping malls, one of the new promising Internet businesses of today, are opening business everyday. And instead of the ordinary image and text type of product display, buyers can now view products from any viewpoint through 3D images and also get more detail information on the product more easily thanks to the new VP technology, visual tools, and statecharts. However the currently used virtual prototyping supporting method does not consist of any database support for sharing the data from different virtual prototype developments and reusing the data in developing other prototypes. And in cases of custom order products, there is no linkage with the virtual product database that enables buyers in cyberspace such as cybermalls to try out the products before purchasing. This paper is purported for being applied as the basis for planning the construction of a complete CRM method applied cyber shopping mall that can accommodata all the demands and requests from customers. And the database supporting VP framework that supports data sharing and collaboration between virtual prototype developers and manufacturing custom order products is suggested for this purpose.