• Journal of Interdisciplinary Genomics
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• v.2 no.1
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• pp.10-12
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• 2020

Coffin-Lowry syndrome (CLS) is a genetic disorder characterized by intellectual disability, typical facial features, and skeletal abnormalities. But this syndrome shows highly variable clinical manifestations, and can't be diagnosed with conventional chromosome analysis or comparative genomic hybridization, leading to delayed diagnosis. Here we report an 18-year-old boy with CLS diagnosed by whole exome sequencing. Our patient initially presented with developmental delay, facial dysmorphism at the age of 1. At the age of 18, he developed orthopnea due to mitral regurgitation. At the 22 years of age, he was diagnosed as CLS diagnosed by whole exome sequencing. Our case implies that clinical suspicion is important for early diagnosis, and advanced diagnostic tools such as WES should be considered in suspected cases.

• Journal of Korean Society for Quality Management
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• v.36 no.4
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• pp.37-46
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• 2008

There are big differences in six sigma projects between manufacturing processes and transactional/service processes. This paper analyzed the differences between the two areas by examining 18 six sigma case studies in Korean companies. To characterize six sigma case studies, step-by-step questions and check criteria were developed based on 12 step DMAIC methodology. On the basis of those characterized data, the differences between two areas were analyzed. Significant differences were found in the number of CTQs, validation of measurement systems, methods to determine improvement objectives, the methods to elicit improvement plans and types of control systems. The most significant difference was that statistical tools were widely used in manufacturing processes, but qualitative tools were used in transactional/service processes during improvement phase.

• Computers and Concrete
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• v.5 no.3
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• pp.243-260
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• 2008

The present article summarises the fundamental characteristics of concrete behaviour which underlie the formulation of an engineering finite element model capable of realistically predicting the behaviour of (plain or reinforced) concrete structural forms in a wide range of problems ranging from static to impact loading without the need of any kind of re-calibration. The already published evidence supporting the proposed formulation is complemented by four additional typical case studies presented herein; for each case, a comparative study is carried out between numerical predictions and the experimental data which reveals good agreement. Such evidence validates the material characteristics upon which the FE model's formulation is based and provides an alternative explanation regarding the behaviour of structural concrete and how it should be modelled which contradicts the presently (widely) accepted assumptions adopted in the majority of FE models used to predict the behaviour of concrete.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.04a
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• pp.431-435
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• 2008

Geothermal heat pump system using standing column wells as their ground heat exchanger can be used as a highly efficient source of heating and cooling in massive buildings. But there is no case of a small scale residential house. So this study estimated heating coefficient of performance(COP) of geothermal heat pump system using standing column well type which is excellent in heat recovery in the residential house. As a result of analysis, The COP of heat pump is over average 6 and is excellent. And in consequence of making a comparative study according to the bleeding, the cop is higher in the case of bleeding. Therefore, bleeding affects the performance of the system. This study has shown performance result that stands on actual data. Therefore, this study provides ground data that needs when a low capacity of system designs for a residence with confidence elevation.

• Speech Sciences
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• v.1
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• pp.27-38
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• 1997

The differences in French Intonation between French and Korean learners can be applied to French intonation education. One native French speaker and three native Korean speakers who learned French language at High school were selected for this study. The subjects spoke test phrases based on the different syntactic structures. High-Speed speech Analysis system(RILP) was used for this experiment. The different intonation curves were showed at the end of phrase and at the beginning of phrase between French and Korean learners. At the end of phrases, French intonation appeared to have increasing and decending pitch contours in the case of wh-question, exclamation and finality. However, Korean learner's intonation showed only increasing pitch contours. At the beginning of phrase, French intonation shows decending pitch contours in the case of minor continuation and command. In contrast, Korean learner's intonation appeared to have increasing pitch contours. The new intonation training system using PC can have great effect on education of French as a second language.

• Journal of the Korean Society of Safety
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• v.29 no.4
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• pp.180-183
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• 2014

The purpose of this study is to assess for scattering object for the missile ejection round due to analysis of the human body effectiveness safely. To achieve this goal the measurement method of scattering objects by comparative 2 measurement methods studied, the risk of scattering of the object is evaluated. Result of this study, applied in Europe and Japan, based on the safety criteria for the human body effectiveness when missile ejection round. data showed is not effectiveness to the operator's body safely. Data showed that satisfies the safety criteria for missile ejection round in Europe and Japan through the similarity for the case studies. In case of these safety criteria does not exist regulation in South Korea, this study will be referred as guidelines are considered.

• Journal of Haehwa Medicine
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• v.23 no.1
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• pp.21-55
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• 2014

Objectives : This report describes the original references of 154 formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam. Methods : This study analyzes the original references of 154 formulas including Rhei Rhizoma as a key component in Dongeuibogam. Results : There were five types as follows: 1.There is no exact match between 154 formulas in Dongeuibogam and the original formulas in references. 2. Case that could not found the original formula in reference: 22%. 3. Case that the citation is the similar to the original reference: 4%. 4. Case that the citation is not same to expression but contents basically: 73%. 5. Case of addition of content: 1% Conclusions : Most formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam are similar to the contents in the original references. But we can find that Heo Jun, who writes Dongeuibogam, modifies the contents for his intention of editing, idea and situation in Korea.

• The Journal of the Korean life insurance medical association
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• v.3 no.1
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• pp.149-162
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• 1986

We had experienced very rare a case of renal cell carcinoma through ultrasonic diagnosis, september, 1985 at medical dept. Dae Han Kyoyuk Ins. Company. The conclusions that we gained, making a comparative-analysis of operation's view and ultrasonic view are as follows; 1. Echolucent area which was $0.6cm^2$ size in the center of tumor was shown by ultrasonography, we noticed it occured necrosis or cystic change and the extracts grossly after. operation accorded with ultrasonic view. 2. Tumor was 65mm in diameter on ultrasonography and made clear 55mm in diameter after operation 3. There was not fever, anemia, even typical triad of renal cell carcinoma, blood pressure was within normal limits. 4. The case was stage I by Robson's Modification method. 5. The case was clear cell type by classifying of histology. 6. The affected site was left side and origin was lower pole of the kidney. 7. After radical nephrectomy, until present prognosis was favorable and he exists.

• The Journal of the Korean life insurance medical association
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• v.3 no.1
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• pp.233-244
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• 1986

We'd experienced a case of primary hepatoma at medical department, Dae han Kyoyuk Ins. Company January 1985. As it was found very early stage, we made out the case long term-survival possibility unexpectedly. The conclusions we gained, making comparative-analysis of ultrasonic view and operation's view are as follows; 1. By ultrasonography, echogenicity of tumor was increased type as compared with liver parenchyme. 2. The margin of the primary hepatoma by ultrasonography encapsulated well and the extraction after operation was same. 3. The boundary of tumor was clear. 4. The space-occupying lesion in liver was solitary. 5. The affected site was left lobe of the liver. 6. We couldn't discover a little fluid echo in upper abdomen on the ultrasonography, but could see in the cul-de-sac area and it accorded with the gross finding during laparotomy. 7. The case was cholangiocarcinoma in view of pathologic histology. 8. After the operation of lobectomy. the prognosis which was passed a months was very satisfactory and she exists until present.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.3
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• pp.262-268
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• 2020

The IMO (International Maritime Organization) has mandated the restriction of SOx emissions to 0.5 % for all international sailing vessels since January 2020. And, a number of countries have designated emission control areas for stricter environmental regulations. Three representative methods have been suggested to cope with these regulations; using low-sulphur oil, installing a scrubber, or using LNG (Liquefied Natural Gas) as fuel. In this paper, economic analysis was performed by comparing the method of installing a scrubber with the method of using low-sulphur oil without installing additional equipment. We suggested plausible layouts and compared the pros and cons of dif erent scrubber types for retrofitting. We selected an international sailing ship as the target vessel and estimated payback time and benefits based on navigation route, fuel consumption, and installation and operation costs. Two case of oil prices were analyzed considering the uncertainty of fuel oil price fluctuation. We found that the expected payback time of investment varies from 1 year to 3.5 years depending on the operation ratio of emission control areas and the fuel oil price change.