• 제목/요약/키워드: comparable study

검색결과 2,682건 처리시간 0.034초

Intraindividual Comparison of Hepatocellular Carcinoma Washout between MRIs with Hepatobiliary and Extracellular Contrast Agents

  • Yeun-Yoon Kim;Young Kon Kim;Ji Hye Min;Dong Ik Cha;Jong Man Kim;Gyu-Seong Choi;Soohyun Ahn
    • Korean Journal of Radiology
    • /
    • 제22권5호
    • /
    • pp.725-734
    • /
    • 2021
  • Objective: To intraindividually compare hepatocellular carcinoma (HCC) washout between MRIs using hepatobiliary agent (HBA) and extracellular agent (ECA). Materials and Methods: This study included 114 prospectively enrolled patients with chronic liver disease (mean age, 55 ± 9 years; 94 men) who underwent both HBA-MRI and ECA-MRI before surgical resection for HCC between November 2016 and May 2019. For 114 HCCs, the lesion-to-liver visual signal intensity ratio (SIR) using a 5-point scale (-2 to +2) was evaluated in each phase. Washout was defined as negative visual SIR with temporal reduction of visual SIR from the arterial phase. Illusional washout (IW) was defined as a visual SIR of 0 with an enhancing capsule. The frequency of washout and MRI sensitivity for HCC using LR-5 or its modifications were compared between HBA-MRI and ECA-MRI. Subgroup analysis was performed according to lesion size (< 20 mm or ≥ 20 mm). Results: The frequency of portal venous phase (PP) washout with HBA-MRI was comparable to that of delayed phase (DP) washout with ECA-MRI (77.2% [88/114] vs. 68.4% [78/114]; p = 0.134). The frequencies were also comparable when IW was allowed (79.8% [91/114] for HBA-MRI vs. 81.6% [93/114] for ECA-MRI; p = 0.845). The sensitivities for HCC of LR-5 (using PP or DP washout) were comparable between HBA-MRI and ECA-MRI (78.1% [89/114] vs. 73.7% [84/114]; p = 0.458). In HCCs < 20 mm, the sensitivity of LR-5 was higher on HBA-MRI than on ECA-MRI (70.8% [34/48] vs. 50.0% [24/48]; p = 0.034). The sensitivity was similar to each other if IW was added to LR-5 (72.9% [35/48] for HBA-MRI vs. 70.8% [34/48] for ECA-MRI; p > 0.999). Conclusion: Extracellular phase washout for HCC diagnosis was comparable between MRIs with both contrast agents, except for tumors < 20 mm. Adding IW could improve the sensitivity for HCC on ECA-MRI in tumors < 20 mm.

우리 국민의 철 섭취량 평가: 식품별 영양성분 함량자료와 한국형 총식이조사 기반 추정량 비교 (Dietary Iron Intake of Koreans Estimated using 2 Different Sources of Iron Contents are Comparable: Food & Nutrient Database and Iron Contents of Cooked Foods in the Korean Total Diet Study)

  • 이지연;권성옥;여윤재;서민정;이계호;김초일
    • 대한지역사회영양학회지
    • /
    • 제27권3호
    • /
    • pp.245-253
    • /
    • 2022
  • Objectives: This study was conducted to find out if the dietary iron intake of Koreans estimated by 2 different methods (iron content sources) using the food intake data from the Korea National Health and Nutrition Examination Survey (KNHANES) are comparable. One method was based on the KNHANES's Food & Nutrient Database (FND) derived mainly from the Korean Food Composition Table and the other used the iron content (IC) of food samples processed in the Korean Total Diet Study (KTDS). Methods: Dietary intake data from the 2013-2016 KNHANES was used to select representative foods (RFs) in KTDS for iron analysis. Selection of the RFs and cooking methods for each RF (RF × cooking method pair) was performed according to the 'Guidebook for Korean Total Diet Studies' and resulted in a total of 132 RFs and 224 'RF × cooking method' pairs. RFs were collected in 9 metropolitan cities nationwide once or twice (for those with seasonality) in 2018 and made into 6 composites each, based on the origin and season prior to cooking. Then, the RF composites prepared to a 'table ready' state for KTDS were analyzed by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Dietary iron intake of the Korean population was estimated using only RFs' intake data based on the 2 sources of iron content, namely FND-KNHANES and IC-KTDS. Results: RFs in KTDS covered 92.0% of total food intake of Koreans in the 2016-2018 KNHANES. Mean iron intake of Koreans was 7.77 mg/person/day by IC-KTDS vs 9.73 mg/person/day by FND-KNHANES. The major food groups contributing to iron intake were meats (21.7%), vegetables (20.5%), and grains & cereals (13.4%) as per IC-KTDS. On the other hand, the latter source (FND-KNHANES) resulted in a very different profile: grains & cereals (31.1%), vegetables (16.8%), and meats (15.3%). While the top iron source was beef, accounting for 8.6% in the former, it was polished rice (19.2%) in the latter. There was a 10-fold difference in the iron content of polished rice between 2 sources that iron intakes excluding the contribution by polished rice resulted in very similar values: 7.58 mg/person/day by IC-KTDS and 7.86 mg/person/day by FND-KNHANES. Conclusions: This study revealed that the dietary iron intake estimated by 2 different methods were quite comparable, excluding one RF, namely polished rice. KTDS was thus proven to be a useful tool in estimating a 'closer-to-real' dietary intake of nutrients for Koreans and further research on various nutrients is warranted.

A Comparative Study on Bayes Estimators for the Multivariate Normal Mcan

  • Kim, Dal-Ho;Lee, In suk;Kim, Hyun-Sook
    • Communications for Statistical Applications and Methods
    • /
    • 제6권2호
    • /
    • pp.501-510
    • /
    • 1999
  • In this paper, we consider a comparable study on three Bayes procedures for the multivariate normal mean estimation problem. In specific we consider hierarchical Bayes empirical Bayes and robust Bayes estimators for the normal means. Then three procedures are compared in terms of the four comparison criteria(i.e. Average Relative Bias (ARB) Average Squared Relative Bias (ASRB) Average Absolute Bias(AAB) Average Squared Deviation (ASD) using the real data set.

  • PDF

Kernel-Trick Regression and Classification

  • Huh, Myung-Hoe
    • Communications for Statistical Applications and Methods
    • /
    • 제22권2호
    • /
    • pp.201-207
    • /
    • 2015
  • Support vector machine (SVM) is a well known kernel-trick supervised learning tool. This study proposes a working scheme for kernel-trick regression and classification (KtRC) as a SVM alternative. KtRC fits the model on a number of random subsamples and selects the best model. Empirical examples and a simulation study indicate that KtRC's performance is comparable to SVM.

여성전문병원의 거주후 평가에 관한 연구 (Validating a Building Prototype: A Post-Occupancy Evaluation of a Women's Medical Center)

  • 이형숙
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
    • /
    • 제4권6호
    • /
    • pp.95-102
    • /
    • 1998
  • The validity of new building prototypes must be confirmed to support the design process for comparable future projects. This project invovled a post-occupancy study at a new women's health center that provides LDR/P (labor, delivery, recovery, postpartum). The study's objectives were to test whether the intentions of the designers were effectively executed, to provide feedback to the hospital about the new facility, and to provide design guidelines.

  • PDF

이동격자태풍모델을 이용한 2006년 태풍의 진로 및 강도 예측성능 평가 (Performance of MTM in 2006 Typhoon Forecast)

  • 김주혜;추교명;김백조;원성희;권혁조
    • 대기
    • /
    • 제17권2호
    • /
    • pp.207-216
    • /
    • 2007
  • The Moving-nest Typhoon Model (MTM) was installed on the Korea Meteorological Administration (KMA)'s CRAY X1E in 2006 and started its test operation in August 2006 to provide track and intensity forecasts of tropical cyclones. In this study, feasibility of the MTM forecast is compared with the Global Data Assimilation and Prediction System (GDAPS) of the KMA and the operational typhoon forecast models in the Japan Meteorological Agency (JMA), from the sixth tropical cyclone to the twentieth in 2006. Forecast skills in terms of the storm position error of the two KMA models were comparable, but MTM showed a slightly better ability. While both GDAPS and MTM produced larger errors than JMA models in track forecast, the predicted intensity was much improved by MTM, making it comparable to the JMA's typhoon forecast model. It is believed that the Geophysical Fluid Dynamics Laboratory (GFDL) bogus initialization method in MTM improves the ability to forecast typhoon intensity.

측모 두부 방사선사진과 컴퓨터 영상사진 (Dolphin Imaging System)의 계측치 에 관한 비교 (COMPARISONS OF MEASUREMENTS OBTAINED FROM LATERAL CEPHALOMETRIC RADIOGRAPHS AND DIGIGRAPHS OF DOLPHIN IMAGING SYSTEM)

  • 박해준;박영철
    • 대한치과교정학회지
    • /
    • 제24권3호
    • /
    • pp.521-534
    • /
    • 1994
  • The purpose of this study was to compare the differences in measurements between cephalometric radiographs and digigraphs of Dolphin Imaging System. 26 Korean adult male and 24 adult female with normal occlusion were selected. For each subject lateral cephalogram was taken. Digitizing with Digigraph Work Station of Dolphin in System. was performed as well. 50 tracings and 50 digigraphs were analyzed with Yonsei, Ricketts, Burstone analyses. The comparable measurements between tracing group and digigraph group were statistically analyzed. The results were as follows: 1. 13 of 64 comparable measurements did not show any statistically significant difference (P>0.05) between tracing group and digigraph group. 2. Three of the measurements with FH plane as a reference plane did not show any statistically insignificant difference. All measurement with SN plane as a reference plane showed statistically significant difference(p<0.05). 3. The measurements which showhed no statistically significant difference were mostly short distance linear measurements while most of the angular measurements showed statistically significant difference(p<0.05).

  • PDF

돼지 생식기호흡기증후군 바이러스항체 검색에 있어 간접형광항체법(IFA) 과 효소면역법(ELISA)의 진단효율 비교 (Comparison between indirect immunofluorescent antibody (IFA) test and enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to porcine reproductive and respiratory syndrome virus(PRRSV))

  • 박최규;류영수;이창희;정종욱
    • 대한수의학회지
    • /
    • 제38권2호
    • /
    • pp.314-318
    • /
    • 1998
  • An establishment of effective control measures to PRRSV infection in swine industry depends on a sensitive and specific diagnosis to detect either viral antigen and/or antibodies to PRRSV. Several diagnostic methods are available to detect antibodies against PRRSV, including IPMA, IFA and ELISA tests have been successfully developed. Sensitivity of the indirect immunofluorescent assay in MA-104 cells using Korean field isolate PL96-1 was superior to that of VR-2332 and field isolate PL96-2. Sensitivity and specificity of the IFA test with PL96-1 were comparable to those of commercial ELISA test kit but ELISA test was more sensitive for the detection of declining antibodies to PRRSV in finishing pigs. In this study we concluded that IFA and ELISA test could be utilized to detect antibodies to PRRSV and the results generated from these two tests were comparable and there were no significant difference between these two tests.

  • PDF

Effects of a New Selective Phosphodiesterase Type 5 Inhibitor, KJH-1002, on the Relaxation of Rabbit Corpus Cavernosum Tissue

  • Cho, Eun-Young;Chung, Sung-Hyun;Kim, Joong-Hyup;Kim, Dong-Hyun;Jin, Cang-Bae
    • Biomolecules & Therapeutics
    • /
    • 제11권4호
    • /
    • pp.232-237
    • /
    • 2003
  • The present study examined functional effects of a new selective phosphodiesterase type 5 inhibitor, 1-[4-ethoxy-3-(6,7-dihydro-1-methyl-7-thioxo-3-propyl-1H-pyrazolo[ 4,3]pyrimidin-5-yl)phenylsulphonyl]-4-methyl piperazine (KJH-1002), in the isolated rabbit corpus cavernosum (RCC). Relaxing effects of KJH-1002 were also compared with those of sildenafil, which is currently used as an oral therapy for penile erectile dysfunction. In the isolated RCC precontracted with phenylephrine, both KJH-1002 and sildenafil in the concentration range of 1 to 1000 nM, produced a comparable potentiation of the electical field stimulation-induced relaxation in a concentration-dependent manner. In the sodium nitroprusside (SNP)-induced relaxation, the $IC_{50}$/ values, concentrations of SNP required to produce a 50% relaxation of the phenylephrine-induced contraction, were significantly decreased to the similar extent by treatments with KJH-1002 and sildenafil. The results suggest that a new selective phosphodiesterase type 5 inhibitor, KJH-1002, has an augmentative effect on penile erection comparable to that of sildenafil and can be useful for the treatment of erectile dysfunction.

한국과 영국의 건강불평등 국가 데이터베이스 비교: 중독 물질 오남용 관련 정신건강 및 호흡기 질환을 중심으로 (Comparison of National Database of Health Inequality between Korea and the UK: Focusing on Substance Misuse Related Mental Health and Respiratory Diseases)

  • 이인향
    • 한국임상약학회지
    • /
    • 제31권3호
    • /
    • pp.216-230
    • /
    • 2021
  • Objective: Taking action on health inequalities starts with the production of information laying out the problems of inequalities, but Korean society has no national database to view related data at a glance. This study aimed to compare Korean national database with the Public Health Profile (PHP), a health inequality database of the UK. Methods: Data were collected from the websites of government and relevant organizations in the both countries between March and August 2020, which was updated in August 2021. Two themes including Co-occurring substance misuse and mental health issues in mental health and INteractive Health Atlas of Lung conditions in England were selected for comparison in terms of data accessibility, data usability and data visualization. Results: The British PHP is being served on a web-based platform, Fingertips. The data collected at the regional level were presented on 31 health inequality themes. The data are displayed at a level that can be compared between comparable communities, and visualized into various tables and figures. Comparable Korean data were scattered in several themes and websites, and mostly provided as a 17 administrative region base, which was too vast to make a meaningful comparisons. Conclusion: The findings proposed several considerations which could be useful for establishing a database of health inequality in the Korean society.