• 한국물환경학회지
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• 제35권6호
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• pp.459-469
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• 2019

The ozonation of sulfamethoxazole (SMX) was performed at 20℃ using a pilot scale countercurrent bubble column reactor. Ozonation systems were combined with UV irradiation and TiO₂ addition. As the oxidation reaction proceeded in each treatment system, the pH of the sample decreased and in the O₃/UV/TiO₂ system, the pH change was the largest from 4.54 to 2.02. Under these experimental conditions, the scavenger impact of carbonate is negligible. The highest COD and TOC removal rate was observed in the O₃/UV/TiO₂ system due to the UV irradiation and the photocatalytic effect of TiO₂. Also, the highest mineralization ratio(ε) value is 0.2 in the O₃/UV/TiO₂ system, which means theoxidation capacity of the systems. The highest SMX degradation rate constants calculated by COD and TOC values (COD and TOC) were 2.15 × 10^-4 sec^-1 and 1.00 × 10^-4 sec^-1 in the O₃/UV/TiO₂ system, respectively. The activation energy (E_a) of ozone treatment follows the Arrhenius law. It was calculated based on _COD and _TOC. Each activation energy decreased in order of single O₃> O₃/TiO₂> O₃/UV > O₃/UV/TiO₂ system. The result showed that ΔH^≠ is more effective than ΔS^≠ in each SMX ozontaionsystem, that is characteristic of the common oxidation reaction.

• 대한임상독성학회지
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• 제14권2호
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• pp.100-106
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• 2016

Purpose: Beta blocker (BB) has been prescribed for anxiety and panic disorder. Patients intoxicated by psychiatric drugs have often been exposed to BB. Moreover, BB overdose has adverse effects including cardiovascular effects, which can be life-threatening. This study was conducted to identify the characteristics of BB intoxication with psychiatric drugs and the adverse effects on the cardiovascular system. Methods: A single center, retrospective study was performed from January 2010 to December 2015. A total of 4,192 patients visited the emergency department (ED) with intoxication, and 69 with BB intoxication were enrolled. Results: Overall, 64 patients (92.8%) of enrolled patients were intoxicated with drugs prescribed for the purpose of psychiatric disorders. Propranolol was the most common BB (62 cases, 96.2%), and the median dose was 140.0 mg (25%-75% 80.0-260.0). Twenty-four patients (37.5%) had experienced cardiovascular events, and these patients tended to have decreased mentality, hypotension and coingestion with quetiapine. An initial mean arterial pressure (MAP) below 65 mmHg (odds ratio 10.069, 95% confidence interval 1.572-64.481, p=0.015) was identified as a factor of cardiovascular event upon multiple logistic regression analysis. Conclusion: Initial MAP below 65 mmHg was a factor of cardiovascular adverse effect in patients of BB intoxication with psychiatric drugs.

• 한국작물학회지
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• 제7권1호
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• pp.97-101
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• 1969

생육형이 다른 대맥품종을 혼파하였을경우 품증종에 일어나는 경합상을 구명하기 위하여 본실험을 행하였던바 그결과를 요약하면 다음과 같다. 1. 장기종인 브흥은 단간종인 수원18호 보다 경합능력이 현저히 높았으며 이러한 경향은 보비구에서 보다 배비구에서 더욱 현저 하였다. 2. 혼파했을 경우 장기종의 간장은 짧아지고 단간종의 간장은 길어 졌으며 이와 반대로 수장에 있어서 단간종은 오히려 짧아지고 장간종은 길어졌다. 3. 수수 및 일수립수는 처리간 차이가 인정되지 않았다. 4. 단파의 경우 수원18호는 보비구가 배비구보다 약간 수량이 많았고 이와 반대로 부흥은 배비구가 보비구보다 현저히 수량이 많았다. 그러나 혼파의 경우에는 전체적으로 배비구에서 보비구보다 현저한 수량의 증가를 나타내고 있다. 5. 장기종인 부흥이 단간종인 수원8호보다 현저히 경합력이 우세하였으며 이러한 경향은 시비량이 증가될수록 크게 나타난다.

• 대한두경부종양학회지
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• 제12권1호
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• pp.32-42
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• 1996

This study was desinged to evaluate the effect of radioactive iodine-131 therapy in differentiated thyroid carcinoma treated at the Presbyterian Medical Center, Chonju during the 20-year period from 1975 to 1994. The authors reviewed 246 patients who received radioactive iodine-131. An analysis of the therapeutic response and survival rates of the 246 patients has been carried out. The male to female ratio was 1 : 3.6. The peak incidence was in the 4th and 6th decades. The histologic findings in the 246 patients were papillary adenocarcinoma in 200 cases, follicular adenocarcinoma in 29 cases, mixed type in 14 cases, and others in 3 cases. Combined treatment modalities of 246 patients consisted of sugery and radioiodine in 222 cases, surgery with radioiodine and external irradiation in 11 cases, and surgery with radioiodine, external irradiation and chemotherapy in 5 cases. 42 of the 246 cases showed recurrence and the commonest type of combined treatment for recurrent case was surgery followed by radioiodine-131. The highest accumulated total dosage of radioiodine-131 was 480mCi in that case femoral metastasis was noticed. The most common locoregional metastatic site was ipsilateral cervical node, and neighbouring muscle, vessel, trachea, recurrent layngeal nerve, in order of frequency. The determinate 10-year survival rate was 91.8% in the group receiving surgery followed by radioiodine-13l and 71.4% in patients receiving surgery, radioiodine-13l with XRT. The determinate 10-year survival rate was better for patients under 40 years of age who received radioiodine as compared to patients over 40 year of age(85.7% vs. 33.3%). The most usual primary therapeutic dosage in the group of cervical lesion was 90$\sim$120mCi after surgery.

• Nutrition Research and Practice
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• 제7권3호
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• pp.172-177
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• 2013

Benign prostatic hyperplasia (BPH) is one of the most common diseases among elderly men. As the old-age population is increasing recently, it is to our interest to observe the growing BPH within them. In BPH, the dihydrotestosterone (DHT) acts as promotes prostate growth. It inhibits enzyme $5{\alpha}$-reductase that is involved in the conversion of testosterone to the DHT activity which reduces the excessive prostate growth. Through experiments, the effects of Phellius linteus water extract performed on the BPH rats were induced by testosterone treatments. For 12 weeks, Sprague-Dawley rats were treated with testosterone for the induction of BPH. Rats were divided into four experimental groups: the not treated group (N), the testosterone injection and D.W treatment group (TN), the testosterone injection and Phellinus linteus treatment group (TP) and testosterone injection and finasteride treatment group (TF). Prostate weight, volume and weight ratio in the TP group and the TF group were significantly lower than the TN group. Testosterone and DHT levels in the TN group were significantly higher than that of the N group. And the TP group was significantly decreased than that of the TN group. While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation; the TP and TF groups showed trophic symptoms and were lined by flattened epithelial cells, thus, the stromal proliferation is relatively low as compared to the TN group. These suggest that Phellinus linteus water extracts may be an useful remedy for treating the benign prostatic hyperplasia.

• 한국한의학연구원논문집
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• 제16권2호
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• pp.143-157
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• 2010

Objectives : The objective of this study was to access the effect of Artemisiae capillaris herba Extracts on the organogenetic reproductive toxicity of New Zealand White rabbits when administered by oral gavage. Methods : Gestational New Zealand White rabbits were dosed from 6 days of gestation to 18 days of gestation. It was conducted in accordance with the recommendations of the KFDA Guideline for Detection of Toxicity to Reproduction for Medicinal Products. In addition, serum AST, ALT, LDH and ALP levels were detected with their necropsy and histopathological observation Results: No significant changes of body weights, gains and food consumption were demonstrated in all dosed groups compared to those of vehicle control group except for 2,000mg/kg-dosing group, which showed significantly increase of body weight compared to that of vehicle control group. Normal gross findings were demonstrated in all tested groups. No significant changes of number of corpora lutea, implantation, implantation rate, number of fetal death, loss rate of post-implantation, number of live youngs at C-section, survival rate of post-implantation, number of male live youngs at C-section, number of female live youngs, sex ratio of live young, external anomalies of live youngs and body weight of live youngs were demonstrated in all dosed groups compared to those of vehicle control group. Although some visceral variations such as thymic reminant in the neck, dilation of renal pelvis, dilated ureter and malpositioned left common carotid artery, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. Some malformations and variation were demonstrated with retardations. However, no significant changes were demonstrated in all dosed groups compared to that of vehicle control group. In addition, similar ossification numbers were detected in sternebrae, metacarpals, metatarsals, phalanges, cervical vertebrae, and sacral and caudal vertebrae. No Artemisiae capillaris herba Extracts treatment-related changes of serum AST, ALT, LDH and ALP levels were demonstrated in all dosed levels in this study. Conclusions : We could conclude that oral administration of Artemisiae capillaris herba Extracts hasn't an influence on the organogenetic reproductive toxicity.

• 대한방사선기술학회지:방사선기술과학
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• 제41권2호
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• pp.123-128
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• 2018

Recently, the use of contrast agents has been increasing as a broader range of tests and dynamic tests have become common due to the development of equipment and imaging techniques such as Multi-Detector CT. However, the side effects of using contrast agents have been reduced by the development of non-ionic contrast agents, but they are still occurring often. The purpose of this study was to propose a method to minimize the side effect of contrast agent by using the amount of contrast agent injected to the brain angiography test to suppress excessive use of contrast agent and analyze the amount of contrast agent. Patients who were prescribed Brain Angiography due to cerebrovascular disease, According to the results of the comparison of the results obtained by dividing into 4 groups of 10ml each according to the amount of contrast medium injected with contrast agent according to the BMI of the patient, BA and SNR were not different between groups, and even if the amount of contrast injection was reduced, there was no problem in the evaluation of CT angiography through 3D reconstruction. This result shows that even if the contrast medium is injected into the blood vessels of the patient first and then the contrast medium is used as the physiological saline solution, the contrast medium is reduced by 40% it can be expected to minimize.

• 대한산업공학회지
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• 제27권4호
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• pp.413-423
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• 2001

Low back disorders (LBDs) are one of the most common and costly work-related musculoskeletal disorders. One of the major possible risk factors of LBDs is to work with static and awkward trunk postures, especially in a complex trunk posture involving flexion, twisting and lateral bending simultaneously. This study is to examine the effect of complex trunk postures on the postural stresses using a psychophysical method. Twelve healthy male students participated in an experiment, in which 29 different trunk postures were evaluated using the magnitude estimation method. The results showed that subjective discomfort significantly increased as the levels of trunk flexion, lateral bending and rotation increased. Significant interaction effects were found between rotation and lateral bending or flexion when the severe lateral bending or rotation were assumed, indicating that simultaneous occurrence of trunk flexion, lateral bending and rotation increases discomfort ratings synergistically. A postural workload evaluation scheme of trunk postures was proposed based on the angular deviation levels from the neutral position. Each trunk posture was assigned numerical stress index depending upon its discomfort rating, which was defined as the ratio of discomfort of a posture to that of its neutral posture. Four qualitative action categories for the stress index were also provided in order to enable practitioners to apply corrective actions appropriately. The proposed scheme is expected to be applied to several field areas for evaluating trunk postural stresses.

• Structural Engineering and Mechanics
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• 제74권4호
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• pp.567-576
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• 2020

Considerable controversy surrounds the choice of the best abutment type for implant prosthetics. The two most common structures are hex and non-hex abutments. The non-hex abutment typically furnishes a larger contact area between itself and the implant than that provided by a hex structure. However, when a hex abutment is loaded, the position of its contact area may be deeper than that of a non-hex abutment. Hence, the purpose of this study is to determine the different biomechanical behaviors of an internal bone-level implant based on the abutment type-hex or non-hex-and clinical crown length under static and cyclic loadings using finite element analysis (FEA). The hex structure was found to increase the implant and abutment stability more than the nonhex structure among several criteria. The use of the hex structure resulted in a smaller volume of bone tissues being at risk of hypertrophy and fatigue failure. It also reduced micromovement (separation) between the implant components, which is significantly related to the pumping effect and possible inflammation. Both static and fatigue analyses, used to examine short- and long-term stability, demonstrated the advantages of the hex abutment over the non-hex type for the stability of the implant components. Moreover, although its impact was not as significant as that of the abutment type, a large crown-implant ratio (CIR) increased bone strain and stress in the implant components, particularly under oblique loading.

• 한국콘텐츠학회논문지
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• 제9권7호
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• pp.37-44
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• 2009

디지털 워터마킹은 디지털 콘텐츠에 워터마크를 삽입함으로써 불법적인 복제를 방지하고, 지적재산권 및 저작권을 보호하며, 소유권을 주장할 수 있는 근거를 제시하는 기술이다. 일반적으로 워터마킹 기법에서는 워터마크를 삽입함으로써 데이터 왜곡과 품질 저하가 불가피하다는 단점이 있다. 이를 극복하기 위하여 원래 데이터를 변경하지 않는 제로-워터마킹 기법들이 최근 제시되고 있다. 이 논문에서는 VQ(Vector Quantization) 방식의 블록 효과를 줄이고, 압축 비율과 품질을 향상시킨 SMVQ(Side Match Vector Quantization) 방식에 대한 제로-워터마킹 체계인 CSMVQ(Chaotic SMVQ)를 제안한다. SMVQ 이미지 압축에서는 동일하게 두 이웃 블록의 접면 정보를 이용하기 위하여 좌측 상단에서 우측 하단으로 진행되므로, 임의의 순서로 블록을 선택하여 워터마크를 삽입할 수 없다. CSMVQ에서는 이전 에 부호화된 (1개에서 4개까지의) 이웃 블록들의 접면 정보를 동적으로 고려하여 부호화를 진행하므로, 무질서한 방식으로 워터마크가 삽입되도록 지원할 수 있다. 이 기법을 적용한 이미지의 품질이 SMVQ보다 우수하며, 샤프닝, 메디안 필터링 등을 이용한 공격에도 워터마크가 강인함을 보여준다.