• 제목/요약/키워드: combined actions

검색결과 154건 처리시간 0.027초

Utilization of Planned Routes and Dead Reckoning Positions to Improve Situation Awareness at Sea

  • Kim, Joo-Sung;Jeong, Jung Sik;Park, Gyei-Kark
    • International Journal of Fuzzy Logic and Intelligent Systems
    • /
    • 제14권4호
    • /
    • pp.288-294
    • /
    • 2014
  • Understanding a ship's present position has been one of the most important tasks during a ship's voyage, in both ancient and modern times. Particularly, a ship's dead reckoning (DR) has been used for predicting traffic situations and collision avoidance actions. However, the current system that uses the traditional method of calculating DR employs the received position and speed data only. Therefore, it is not applicable for predicting navigation within the harbor limits, owing to the frequent changes in the ship's course and speed in this region. In this study, planned routes were applied for improving the reliability of the proposed system and predicting the traffic patterns in advance. The proposed method of determining the dead reckoning position (DRP) uses not only the ships' received data but also the navigational patterns and tracking data in harbor limits. The Mercator sailing formulas were used for calculating the ships' DRPs and planned routes. The data on the traffic patterns were collected from the automatic identification system and analyzed using MATLAB. Two randomly chosen ships were analyzed for simulating their tracks and comparing the DR method during the timeframes of the ships' movement. The proposed method of calculating DR, combined with the information on planned routes and DRPs, is expected to contribute towards improving the decision-making abilities of operators.

Beneficial effects of Panax ginseng for the treatment and prevention of neurodegenerative diseases: past findings and future directions

  • Kim, Ki Hyun;Lee, Dahae;Lee, Hye Lim;Kim, Chang-Eop;Jung, Kiwon;Kang, Ki Sung
    • Journal of Ginseng Research
    • /
    • 제42권3호
    • /
    • pp.239-247
    • /
    • 2018
  • In recent years, several therapeutic drugs have been rationally designed and synthesized based on the novel knowledge gained from investigating the actions of biologically active chemicals derived from foods, plants, and medicinal herbs. One of the major advantages of these naturalistic chemicals is their ability to interact with multiple targets in the body resulting in a combined beneficial effect. Ginseng is a perennial herb (Araliaceae family), a species within the genus Panax, and a highly valued and popular medicinal plant. Evidence for the medicinal and health benefits of Panax ginseng and its components in preventing neurodegeneration has increased significantly in the past decade. The beneficial effects of P. ginseng on neurodegenerative diseases have been attributed primarily to the antioxidative and immunomodulatory activities of its ginsenoside components. Mechanistic studies on the neuroprotective effects of ginsenosides revealed that they act not only as antioxidants but also as modulators of intracellular neuronal signaling and metabolism, cell survival/death genes, and mitochondrial function. The goal of the present paper is to provide a brief review of recent knowledge and developments concerning the beneficial effects as well as the mechanism of action of P. ginseng and its components in the treatment and prevention of neurodegenerative diseases.

Rotational capacity of shallow footings and its implication on SSI analyses

  • Blandon, Carlos A.;Smith-Pardo, J. Paul;Ortiz, Albert
    • Earthquakes and Structures
    • /
    • 제8권3호
    • /
    • pp.591-617
    • /
    • 2015
  • Standards for seismic assessment and retrofitting of buildings provide deformation limit states for structural members and connections. However, in order to perform fully consistent performance-based seismic analyses of soil-structure systems; deformation limit states must also be available for foundations that are vulnerable to nonlinear actions. Because such limit states have never been established in the past, a laboratory testing program was conducted to study the rotational capacity of small-scale foundation models under combined axial load and moment. Fourteen displacement-controlled monotonic and cyclic tests were performed using a cohesionless soil contained in a $2.0{\times}2.0{\times}1.2m$ container box. It was found that the foundation models exhibited a stable hysteretic behavior for imposed rotations exceeding 0.06 rad and that the measured foundation moment capacity complied well with Meyerhof's equivalent width concept. Simplified code-based soil-structure analyses of an 8-story building under an array of strong ground motions were also conducted to preliminary evaluate the implication of finite rotational capacity of vulnerable foundations. It was found that for the same soil as that of the experimental program foundations would have a deformation capacity that far exceeds the imposed rotational demands under the lateral load resisting members so yielding of the soil may constitute a reliable source of energy dissipation for the system.

생약복합제제(生藥複合製劑)의 약효(藥效) 연구(硏究) 제40보(第40報) -사간탕(瀉肝湯)이 중추신경계(中樞神經系), 순환기계(循環器系) 및 간독성(肝毒性에 미치는 작용(作用)- (Studies on the Efficacy of Combined Preparations of Crude Drug(XL) -Effect of Sagan-Tang on the Central Nervous, Cardiovascular System and the Liver Damage-)

  • 홍남두;배형섭;노영수;김남재;김진식
    • 생약학회지
    • /
    • 제20권3호
    • /
    • pp.196-203
    • /
    • 1989
  • Experimental studies were conducted to investigate the effect of Sagan-Tang on analgesic, sedative, antipyretic, isolated ileum and blood vessel and so on. The results of this investigation were summarized as follows; Analgesic action by the acetic acid stimulating method in mice were recognized. Prolonging action against the hypnotic duration induced by thiopental-Na was noted in mice. Antipyretic effect in typhoid vaccine febrile rats was recognized. Spontaneous motility of the isolated ileum of mice was suppressed and contractions of the isolated ileum of mice and guinea-pig induced by accetylcholine chloride, barium chloride and histamine were remarkably inhibited. Vaso-diating and hypotensive actions were recognized in rabbits. GOT and GPT activities in the serum of rats damaged by $CCl_4$ and galactosamine were decreased remarkably.

  • PDF

위장질환 치료용 의약조성물(DWP 301)의 일반약리작용 (General Pharmacology of DWP 301, a New Combined Drug for Gastroduodenal Diseases)

  • 임승욱;염제호;김영만;심점순;박남준;장병수;연제덕;김병오;강진석
    • Biomolecules & Therapeutics
    • /
    • 제2권4호
    • /
    • pp.347-360
    • /
    • 1994
  • The general and some pharmacological actions of DWP 301 were investigated in animals and the following results were obtained. In central nervous system, DWP 301 had no effects on the pentobarbital induced anaesthesia, rotarod test, traction test, analgesic action, anticonvulsant action in mice and body temperature in rat. But DWP 301 showed a little decrease of locomotor activity at a dose of 3,000 mg/kg. From these results, DWP 301 was considered to have little pharmacological effect on the central nervous system. Furthermore, DWP 301 had no influences on the normal blood pressure and heart rate. DWP 301 showed no effect on the isolated guinea pig ileum, trachea, right atrium, and nonpregnant rat uterus. But, in the isolated guinea pig vas deference, DWP 301 had showed inhibitory effect on the contractions produced by norepinephrine. DWP 301 showed rise of gastric juice pH and decrease of urine volume. Also, DWP 301 had no effect on the gastrointestinal motility and blood aggregation. From these results, it is concluded that the general pharmacological effect of DWP 301 are similar to or weaker than M and AGA.

  • PDF

간장질환 치료용 의약조성물(DWP 305)의 일반약리작용 (General Pharmacology of DWP 305, a New Combined Drug for Hepatic Diseases)

  • 임승욱;염제호;김영만;심점순;박남준;장병수;연제덕;김병오;강진석
    • Biomolecules & Therapeutics
    • /
    • 제2권2호
    • /
    • pp.173-184
    • /
    • 1994
  • The general and some pharmacological actions of DWP 305 were investigated in animals and the following results were obtained. In central nervous system, DWP 305 had no effects on the pentobarbital induced anaesthesia, locomotor activity, rotarod test, traction test, analgesic action in mice and body temperature in rat. DWP 305 showed no depressive action on convulsion induced by strychnine, electronic shock and pentylenetetrazole. From these results, DWP 305 was considered to have no pharmacological effect on the central nervous system. Furthermore, DWP 305 had no influences on the normal blood pressure and heart rate. In the isolated ileum of guinea pig, DWP 305 inhibited contractive effects against the acetylcholine (10$^{-6}$ g/mι), histamine (10$^{-6}$ g/mι), 5-hydroxytryptamine (10$^{-6}$ g/mι) and BaCl$_2$(10$^{-4}$ g/mι) at a concentration of 2.15$\times$10$^{-4}$ g/ml in bath. In the isolated trachea and vats deference, DWP 305 showed no effect on the contractions produced by histamine and norepinephrine, respectively. DWP 305 showed inhibitory effect on the contractions produced by acetylcholine and oxytocin at a concentration of 2.15$\times$10$^{-4}$ g/ml on the isolated nonpregnant rat uterus. DWP 305 had no effect on the isolated right atrium of guinea pig, bile excretion, urine volume, pH, gastrointestinal motility, gastric secretion and blood aggregation.

  • PDF

Service life prediction of a reinforced concrete bridge exposed to chloride induced deterioration

  • Papadakis, Vagelis G.
    • Advances in concrete construction
    • /
    • 제1권3호
    • /
    • pp.201-213
    • /
    • 2013
  • While recognizing the problem of reinforcement corrosion and premature structural deterioration of reinforced concrete (RC) structures as a combined effect of mechanical and environmental actions (carbonation, ingress of chlorides), emphasis is given on the effect of the latter, as most severe and unpredictable action. In this study, a simulation tool, based on proven predictive models utilizing principles of chemical and material engineering, for the estimation of concrete service life is applied on an existing reinforced concrete bridge (${\O}$resund Link) located in a chloride environment. After a brief introduction to the structure of the models used, emphasis is given on the physicochemical processes in concrete leading to chloride induced corrosion of the embedded reinforcement. By taking under consideration the concrete, structural and environmental properties of the bridge investigated, an accurate prediction of its service life is taking place. It was observed that the proposed, and already used, relationship of service lifetime- cover is almost identical with a mean line between the lines derived from the minimum and maximum critical values considered for corrosion initiation. Thus, an excellent agreement with the project specifications is observed despite the different ways used to approach the problem. Furthermore, different scenarios of concrete cover failure, in the case when a coating is utilized, and extreme deicing salts attack are also investigated.

Evaluation of ASCE 61-14 NSPs for the estimation of seismic demands in marginal wharves

  • Smith-Pardo, J. Paul.;Reyes, Juan C.;Sandoval, Juan D.;Hassan, Wael M.
    • Structural Engineering and Mechanics
    • /
    • 제69권1호
    • /
    • pp.95-104
    • /
    • 2019
  • The Standard ASCE 61-14 proposes the Substitute Structure Method (SSM) as a Nonlinear Static Procedure (NSP) to estimate nonlinear displacement demands at the center of mass of piers or wharves under seismic actions. To account for bidirectional earthquake excitation according to the Standard, results from independent pushover analyses in each orthogonal direction should be combined using either a 100/30 directional approach or a procedure referred to as the Dynamic Magnification Factor, DMF. The main purpose of this paper is to present an evaluation of these NSPs in relation to four wharf model structures on soil conditions ranging from soft to medium dense clay. Results from nonlinear static analyses were compared against benchmark values of relevant Engineering Design Parameters, EDPs. The latter are defined as the geometric mean demands that are obtained from nonlinear dynamic analyses using a set of 30 two-component ground motion records. It was found that SSM provides close estimates of the benchmark displacement demands at the center of mass of the wharf structures. Furthermore, for the most critical pile connection at a landside corner of the wharf the 100/30 and DMF approaches produced displacement, curvature, and force demands that were reasonably comparable to corresponding benchmark values.

고문헌 속 언어를 통한 한국의 고전화장 시각화 방안 연구 (A Study on the Visualization of Classic Makeup in Korea through the Language in Old Documents)

  • 방기정
    • 패션비즈니스
    • /
    • 제25권1호
    • /
    • pp.96-107
    • /
    • 2021
  • The purpose of this study was to determine how to visualize classic makeup through Korean visual language in old literature. It provides consumers with creativity to understand and communicate and proposes a new conceptual visualization model. The research method was carried out by drawing from old literature studies, previous reproduction records, examples, and international standard diagram text language expression. First, the visualization work expressed in visual language in old literature was an objective and efficient method of information delivery as a characteristic of information design. Second, visual language expressed in old documents could be divided into makeup materials and actions. Also, the diagrams were appropriate for visualizing materials and materials for storytelling. Third, in the visualization of Korean classic makeup in old literature, images were more appropriate than diagrams in the case of action. The researcher proposed a method of visualizing historical knowledge that went one step beyond the existing simple event timing method. Timeline, correlation diagram, image, and text were combined in various ways to find the most effective historical knowledge visualization method. The representation of Korean classic makeup goes beyond the meaning of language or text and is the cultural content of re-creation, which requires systematic globalization.

Effects of Action Observation Training and Mirror Therapy on the Electroencephalograms of Stroke Patients

  • Lee, Ho Jung;Lee, Jong Su;Kim, Young Mi
    • The Journal of Korean Physical Therapy
    • /
    • 제33권2호
    • /
    • pp.106-113
    • /
    • 2021
  • Purpose: This study examined the effectiveness of action observation training (AOT) and mirror therapy in improving the electroencephalograms (EEG) of stroke patients. Methods: Patients were allocated randomly to three groups: an action observation training with activity (AOTA) group (n=12), a mirror therapy with activity (MTA) group (n=11), and an AOT-only group (n=12). All groups received conventional physiotherapy in five 60-minute sessions over six weeks. The AOTA, MTA, and AOT groups practiced AOTA, MTA, and AOT, respectively, in three 30-minute sessions over six weeks. The differences between the pre- and post-treatment EEGs were assessed using a paired t-test. Comparisons between the groups were performed using one-way ANOVA. Results: The participants in the AOTA and MTA groups showed significant improvement in the EEG. AOTA improved the alpha waves of the prefrontal, temporal, and parietal lobes significantly (p<0.05). MTA improved the alpha waves of the temporal lobe significantly (p<0.05). AOT did not result in significant improvement Conclusion: AOTA and MTA improve stroke patients' EEGs. Mirror neuron activation combined with conventional stroke physiotherapy promotes motor recovery and functioning. The effect is enhanced when the actions are executed after observation. Further research into mirror neuron activation will be needed to develop methods to improve the EEGs of stroke patients.