• 대한임상검사과학회지
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• 제38권3호
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• pp.166-172
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• 2006

Metallo-${\beta}$-lactamase (MBL) can hydrolyze all ${\beta}$-lactams except monobactams and frequently coexists with various antibiotic resistance genes such as aminoglycoside resistance, sulfonamide resistance gene, etc. Therefore, the effective antibiotics against infections by these bacteria are markedly limited or can't even be found. We tried to search in-vitro antimicrobial combinations with synergistic effects for a VIM-2 type MBL producing Pseudomonas aeruginosa, isolated from clinical specimen. On the selection of antibiotic combinations with synergistic effects, we performed a one disk synergy test, modified Pestel's method, in agar without aztreonam (AZT). The bacteriostatic synergistic effects of this tests were scored as $S_1$ (by susceptibility pattern in agar without antibiotics), $S_2$ (by the change of susceptibility in agar with or without antibiotics) and $S_3$ ($S_1$ + $S_2$) and was classified into weak (1 point), moderate (2 points) and strong (3 points) by $S_3$ score. Subsequently, we carried out the time-killing curve for the antibiotic combinations with the strong synergistic bacteriostatic effect. One VIM-2 type MBL producing P. aeruginosa confirmed by the PCR showed all resistance against all ${\beta}$-lactams except AZT, aminoglycoside and ciprofloxacin. In the one disk synergy test, this isolate showed a strong bacteriostatic synergistic effect for the antibiotic combination of AZT and piperacillin-tazobactam (PIP-TZP) or AZT and amikacin (AN). On the time-killing curve after six hours of incubation, the colony forming units (CFUs/mL) of this bacteria in the medium broth with both combination antibiotics were decreased to 1/18.7, 1/17.1 of the least CFUs of each single antibiotics. The triple antibiotic combination therapy including AZT, PIP-TZP and AN was shown to be significantly synergistic after 8 hrs of exposure. In a VIM-2 MBL producing P. aeruginosa with susceptibility for AZT, the triple antibiotic combination therapy including AZT, PIP-TZP and AN may be considered as an alternative antibiotics modality against the infection by some MBL type. But the antimicrobial combination therapy for many more MBL producing isolates is essential to know as soon as possible for the selection of effective treatment against the infection by this bacteria.

• 한국가정과학회지
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• 제2권2호
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• pp.49-62
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• 1999

The purpose of this study is to evaluate the combination of details on the maternity clothes of one-piece type through visual evaluation which helps compensating pregnant women＇s body defects for their more attractive fashion styles. The data evaluated by a multiple ranking test were analyzed by mean, paired t-test, general linear models procedure and Duncan＇s multiple ranged test. The result are as follows : 1) The pregnant woman wearing the one-piece dress with notched collar, pleats and whole button looks longer in lower part of bodies, smaller in upper body, slimmer, have less appeared bust and abdomen, more balanced as a Whole than when wearing others. And also, it makes a pregnant woman be seen more refined and simple. 2) In case of a pregnant woman, a one-piece dress with notched collar, tuck and whole button makes her look longer in neck, narrower in shoulder, and more active than when wearing others. 3) With roll collar, pleats and whole button, it looks taller and more graceful than when wearing others.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2005년도 추계학술발표대회 개요집
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• pp.171-173
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• 2005

Inconel 617 is a solid solution, nickel-chromium-cobalt-molybdenum alloy with an exceptional combination of high temperature strength and oxidation resistance. The combination of high strenth and oxidation resistance at temperatures over $1800^{\circ}F$ makes Inconel 617 an attractive material for such components as ducting, transition liners in both aircraft and gas turbine. In this study, the weldability and weldment characteristics of Inconel 617 are considered in GTAW associated with the two welding current and with back shielding gas using or not. After GTAW with 120A and 150A current, microstructures and hardness test, bending test, tensile test on room and elevated temperature for the determination of optical welding condition.

• 한국자동차공학회논문집
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• 제7권8호
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• pp.76-82
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• 1999

The object of this study is to find new evalution index for in-cylinder flow characteristics insteady of current swirl, tumble coefficient using steady flow test rig on intake port system. To this end, port flow rig test was conducted on DOHC head varying intake valve lift respectively. Finally combination angular coefficient and inclination angle were introduced as new evaluation index for in-cylinder angular flow characteristics.

• 소성∙가공
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• 제18권1호
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• pp.73-79
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• 2009

In order to investigate the formability of friction stir welded(FSW) tailor welded blanks(TWB) with respect to the base material's directional combination, aluminum alloy AA6111-T4 sheets were welded with three different conjoining types: RD-RD, TD-RD and TD-TD. Here, RD and TD represent rolling and transverse directions, respectively. For experimental formability study, three tests with gradual complexity were performed: the simple tension test with various weld line directions for uni-axial elongation, the hemisphere dome stretching test for biaxial stretching and the cylindrical cup deep drawing test. As a result, all three forming tests showed that RD-RD type samples exhibited the best formability, while TD-TD type sheets showed the least formability performance.

• Advances in concrete construction
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• 제7권3호
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• pp.191-201
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• 2019

Bamboo concrete bond behaviour is investigated through pullout test in this work. The bamboo strip to be used as reinforcement inside concrete is first treated with chemical adhesive to make the bamboo surface impermeable. Various surface coatings are explored to understand their water repellant properties. The chemical action at the bamboo concrete interface is studied through different chemical coatings, sand blasting, and steel wire wrapping treatment. Whereas mechanical action at the bamboo concrete interface is studied by developing mechanical interlock. The result of pullout tests revealed a unique combination of surface treatment and grooved bamboo profile. This combination of surface treatment and a grooved bamboo profile together enhances the strength of bond. Performance of a newly developed grooved bamboo strip is verified against equivalent plain rectangular bamboo strip. The test results show that the proposed grooved bamboo reinforcement, when treated, shows highest bond strength compared to treated plain, untreated plain and untreated grooved bamboo reinforcement. Also, it is observed that bond strength is majorly influenced by the type of surface treatment, size and spacing of groove. The changes in bamboo-concrete bond behavior are observed during the experimentation.

• Biomolecules & Therapeutics
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• 제10권2호
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• pp.124-128
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• 2002

Hantaan (HTN) and Puumala (PUU) viruses are major etiological agents of hemorrhagic fever with renal syndrome (HFRS), an important public health problem in Korea after the Korean War. The objective of present study was to determine allergenic potency of an inactivated combination vaccine against HTN and PUU viruses inflection. As a series of allergenicity assessment, a homologous active systemic anaphylaxis (ASA) and homologous/heterologous passive cutaneous anaphylaxis (PCA) tests using the mice and guinea pigs were carried out. In the ASA test, no anaphylactic symptoms were observed in the guinea pigs sensitized with the vaccine alone as well as the vaccine emulsified with an adjuvant. By homologous PCA test, the vatscine did not induced the potential IgE antibody production in the sera obtained from the sensitized guinea pigs. In addition, IgE against the vaccine was not significantly enhanced from the mice inoculated with the vaccine, which was judged by the heterologous PCA test in rats. On the other hand, the inoculation of ovalbumin appeared to allergenic reactions both in the ASA and PCA tests. The results suggest that a combination vaccine against HW and PUU viruses have no allergenic potential in mice or guinea pigs.

• 한국산업보건학회지
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• 제7권1호
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• pp.99-112
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• 1997

A quantitative fit test, condensation nuclei counting(Portacount 8025, TSI), was performed concurrently with a qualitative fit test, sodium saccharin(FT-10, 3M) to evaluate FF values and to determine the correlation between two methods. Two brands of full facepieces, T, S and two brands of half masks, T, S, were fit tested, respectively, on 103 wearers one time. The FF values obtained by CNC QNFT were lognormally distributed. The FF values for T brand of respirators were statistically very much higher than those for S brand of respirators. For a full facepiece wearer combination having a $FF{\leq}100$, as determined by CNC QNFT, the point estimate of the probability of that combination not being rejected by the saccharin QLFT was found to be 0.09 with 90% confidence that this statistic is not expected to exceed 0.25. For a half mask wearer combination having a $FF{\leq}10$, as determined by CNC QNFT, the point estimate of the probability of that combination not being rejected by the saccharin QLFT was found to be 0.10 with 90%, confidence that this statistic is not expected to exceed 0.23. The uncertainty associated with each estimate, however, is large due to the small number of study subjects with inadequately fitting respirators. This result indicates that saccharin QLFT may be more suitable for adequately fitting respirators than inadequately fitting respirators.

• 디지털융복합연구
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• 제14권12호
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• pp.633-644
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• 2016

본 연구는 대학생들의 피톤치드 아로마 흡입과 운동의 복합 처치가 그들의 대학생활스트레스, 기분상태 및 수면에 미치는 영향을 12주 장기간 실험을 통하여 규명하고자 하였다. 피톤치드 아로마 흡입과 운동의 복합 처치의 효과를 탐색하고자 피톤치드 아로마 흡입군(18명), 운동군(17명), 피톤치드 아로마 흡입군+운동군(17명), 대조군(20명)의 4집단 총 72명을 대상으로 하였으며, 사전측정(0week), 중간측정(6week), 사후측정(12week)으로 구성되는 $4{\times}3$ 반복측정에 의한 요인설계($4{\times}3$ factorial design with repeated measure)로 설계하여 대학생의 대학생활 스트레스 지수, 기분상태의 변화를 살펴보았다. 그 결과 통제집단을 제외한 모든 집단에서 기분상태, 수면, 대학생활스트레스의 점수가 향상된 것으로 나타났다. 특히 피톤치드 아로마 흡입과 운동만을 실시한 집단보다 피톤치드 아로마 흡입과 더불어 운동을 병행한 집단이 더 유익한 효과를 나타냈다는 점에서 매우 의미 있는 연구라고 생각된다.

• 대한간호학회지
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• 제42권6호
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• pp.843-852
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• 2012

Purpose: In this study a recreational combination gymnastics program was provided for women 75 years of age or older and the effects on physical fitness (grip strength, static balance, ability to do complex movement), depression, cognitive function and quality of life were examined. Methods: A quasi-experimental study employing a nonequivalent control group, pre-post design was conducted. Participants included 53 women elders whose cognitive function was within the normal range. The women were assigned to an experimental group (27) or a control group (26). The intervention was conducted twice a week for a period of 12 weeks. Chi-square test, t-test, paired t-test, Wilcoxon rank sum test and Wilcoxon signed rank test were used for data analysis. Results: Following completion of the program, left grip strength (t=2.17, p=.035), right grip strength (t=2.04, p=.046), static balance (t=-2.18, p=.030), depression (z=-2.88, p=.004), cognitive function (t=3.96, p<.001), and quality of life (t=-3.19, p=.002) were significantly better in the experimental group. Conclusion: Findings from this study indicate that recreational combination gymnastics programs are effective in enhancing physical fitness, cognitive function, and quality of life and in decreasing depression for female elders and could therefore be regarded as positive programs for promotion of physical and mental health for older women.