• 제목/요약/키워드: collapse characteristic

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Effect of Molecular Weights of Polyethyleneimine on the Polyplex Formation with Calf Thymus DNA

  • Cho, Tae-Sub;Jungho Han;Kim, Seog K.;Lee, Jae-Cheol
    • Macromolecular Research
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    • v.12 no.3
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    • pp.276-281
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    • 2004
  • In this study we investigated the spectral properties, including electric absorption, circular and linear dichroism (CD and LD), and fluorescence emission, of DNA in a DNA-branched polyethyleneimine (BPEI) polyplex at various polymer molecular weights (M$\_$w/) and BPEI-amine-to-DNA-phosphate ratios (N/P ratios). All BPEIs exhibited a common N/P dependence in their absorption and CD spectra. At N/P ratios < 1.0, we observed some hyperchromism in the absorption spectrum, red-shifts in CD bands, and decreases in LD intensity and fluorescence intensity of intercalated ethidium. At intermediate N/P ratios, complete collapse of all spectra occurred. As the N/P ratio increased further, the polyplex dissolved in water. From its characteristic CD spectrum obtained under these conditions, we conclude that the DNA exists in a B-like form. The fluorescence and LD intensities never recovered even at high N/P ratios- which indicates that the dissolved polyplex possesses positive charges and the DNA in the polyplex is condensed despite its B-form CD spectrum. The N/P range in which the absorption and CD signals collapsed was wider when the BPEIs M$\_$w/ decreased. In the case where the BPEIs M$\_$w/ was 0.8 k, recovery of the absorption and CD spectral properties at a high N/P ratio was never achieved, which suggests that the molecular weight of the polymer plays an important role in its dissolution at a high N/P ratio.

A case study of digital intermediate space designed - The focus on the consumer community - (디지털 매개공간 유형에 관한 사례 연구 - 수용자 커뮤니티를 중심으로 -)

  • 서동진;임종훈
    • Korean Institute of Interior Design Journal
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    • no.29
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    • pp.281-288
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    • 2001
  • It shows 21st century as a networking society that is moving up the concept of global town and being industrialized with regional and personal connections. Individual's original idea and variety of 21th century may be respected by such environmental change, and age (Literary, human axis, technology axis, nature axis, kaining farming axis are central keyword) of culture that cultural capacity of individual becomes important fetters that create added value is forecasted to become. The moaning for space that is unemployment enemy by change of conceptional environment about cultural life and agreeable quality of life by development of Information-Communication technology may be required newly. As it does interaction along with development of science technique and Information-Communication technology, the future environment of various that complex! Is predicted to form network environment (existence space, cyberspace) newly. Human central interest is risen in technology balance hereupon, and these characteristic escaped in physical system that do with functional special quality and require human central and sensitive interaction. First, if examine about phenomenon by Digitize and chance aspect that is risen in 21th century, Digitize is time that action occurs fusion Tuesday that is various and Blur phenomenon of city·space, and the period to collapse the border between several individual. Second, importance more than man-centered and sensitive aspect of functional physical system is risen by digital age with development of technology medium, and as the five digital senses showed up, it suggests a sensual of the times and therefore the interest and direction get set up for the sensual sides of consumers. Third, special quality is, medium enemy by that digital space connotes meaning disk floret, variability, transparency, space red of extensity etc.. to burn and is digitalised, can be risen by symbolic, original individualities and emotional communication's the importance is required sensitivity enemy who is sympathy horn by fusion anger of individual. Technology of new media may open direction of new communication through interface that did not enjoy so far is going to supply new means that can express own to human

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Implementation of oral patient management system using smartphone and embedded imaging module (스마트폰과 임베디드 촬영 모듈을 활용한 구강 환자 관리 시스템 구현)

  • Lee, Hyoun-sup;Youn, Joo-sang;Kim, Jin-deog
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.4
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    • pp.581-586
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    • 2018
  • A common characteristic of many patients whose illness is getting worse is that they miss the treatment red flag. When high subjective symptoms appear or there is no strong pain, this problem arises because it is reluctant to visit the hospital. Gingivitis causes bleeding from the gums in the early and mid-term, and shows mild symptoms of tooth collapse. When treatment is done at this point, it shows a very high effect. However, when you miss the timing of treatment you will have a situation where you can't eat food by causing serious problems in the health of the gums and oral cavity. In this paper, the patient's periodontal image is photographed with a smartphone and transmitted in real time. This is done by the doctor in charge. Then, we propose a design of a patient management system that provides information on the current situation to the patient so as not to miss the timing of treatment.

Seismic Safety Assessment of Long Period Structures Base on Elastic/Inelastic Response Characteristics (장주기구조물의 탄소성응답특성을 고려한 지진안전성 평가)

  • Bang, Myung-Seok
    • Journal of the Korean Society of Safety
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    • v.26 no.3
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    • pp.52-58
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    • 2011
  • The earthquake characteristic assessment of social overhead facilities would be an important examination issue for seismic capacity enhancement. This study is intended to reasonably evaluate the structural behavior of longperiod frame structures considering near-fault and far-fault earthquake characteristics. Elastic/inelastic time history analyses were performd by selecting the objective structure which can precisely reflect the effect of input ground motion. Based on the result of numerical analysis, we have investigated response aspects of shear force, moment, acceleration and displacement according to earthquake characteristics. Moreover, in order to understand the inelastic behavior of the objective structure, we have analyzed and compared collapse modes by considering the occurrence process of plastic hinges. The outcome of this research is expected to provide the basic information for the seismic safety assessment of long-period frame structures.

Electrics and Noise Performances of AlGaN/GaN HEMTs with/without In-situ SiN Cap Layer (In-situ SiN 패시베이션 층에 따른 AlGaN/GaN HEMTs의 전기적 및 저주파 잡음 특성)

  • Yeo Jin Choi;Seung Mun Baek;Yu Na Lee;Sung Jin An
    • Journal of Adhesion and Interface
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    • v.24 no.2
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    • pp.60-63
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    • 2023
  • The AlGaN/GaN heterostructure has high electron mobility due to the two-dimensional electron gas (2-DEG) layer, and has the characteristic of high breakdown voltage at high temperature due to its wide bandgap, making it a promising candidate for high-power and high-frequency electronic devices. Despite these advantages, there are factors that affect the reliability of various device properties such as current collapse. To address this issue, this paper used metal-organic chemical vapor deposition to continuously deposit AlGaN/GaN heterostructure and SiN passivation layer. Material and electrical properties of GaN HEMTs with/without SiN cap layer were analyzed, and based on the results, low-frequency noise characteristics of GaN HEMTs were measured to analyze the conduction mechanism model and the cause of defects within the channel.

Assessment of seismic parameters for 6 February 2023 Kahramanmaraş earthquakes

  • Bilal Balun
    • Structural Engineering and Mechanics
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    • v.88 no.2
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    • pp.117-128
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    • 2023
  • On February 6, 2023, Türkiye woke up with a strong ground motion felt in a wide geography. As a result of the Kahramanmaraş, Pazarcık and Elbistan earthquakes, which took place 9 hours apart, there was great destruction and loss of life. The 2023 Kahramanmaraş earthquakes occurred on active faults known to pose a high seismic hazard, but their effects were devastating. Seismic code spectra were investigated in Hatay, Adıyaman and Kahramanmaraş where destruction is high. The study mainly focuses on the investigation of ground motion parameters of 6 February Kahramanmaraş earthquakes and the correlation between ground motion parameters. In addition, earthquakes greater than Mw 5.0 that occurred in Türkiye were compared with certain seismic parameters. As in the strong ground motion studies, seismic energy parameters such as Arias intensity, characteristic intensity, cumulative absolute velocity and specific energy density were determined, especially considering the duration content of the earthquake. Based on the study, it was concluded that the structures were overloaded far beyond their normal design levels. This, coupled with significant vertical seismic components, is a contributing factor to the collapse of many buildings in the area. In the evaluation made on Arias intensity, much more energy (approximately ten times) emerged in Kahramanmaraş earthquakes compared to other Türkiye earthquakes. No good correlation was found between moment magnitude and peak ground accelerations, peak ground velocities, Arias intensities and ground motion durations in Türkiye earthquakes. Both high seismic components and long ground motion durations caused intense energy to be transferred to the structures. No strong correlation was found between ground motion durations and other seismic parameters. There is a strong positive correlation between PGA and seismic energy parameter AI. Kahramanmaraş earthquakes revealed that changes should be made in the Turkish seismic code to predict higher spectral acceleration values, especially in earthquake-prone regions in Türkiye.

Unsaturated Soil Properties of Compacted Soil at Sub-Zero Temperature (영하온도에서 다짐된 지반의 불포화 특성)

  • Lee, Jeonghyeop;Hwang, Bumsik;Cho, Wanjei
    • Journal of the Korean GEO-environmental Society
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    • v.19 no.3
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    • pp.5-13
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    • 2018
  • Recently, construction disasters in thawing season are increasing due to the ground collapse and it is related to the improper compaction during winter season. Compaction at sub-zero temperature reduces the compaction effect and the research of mechanical properties of thawed soil after winter compaction can be used as useful data to understand the behavior of the ground in the thawing season. On the other hand, the research interest in the unsaturated soil mechanics has been increasing in the field of the geotechnical engineering. Therefore, it is expected that the research of unsaturated characteristics under the compaction of sub-zero temperature and freezing & thawing condition provides information to the researchers in the related fields. Therefore, in this research, unsaturated soil-water characteristics test and unsaturated uniaxial compression test were conducted on the specimens compacted at sub-zero temperature and continuous freezing & thawing condition to investigate change of unsaturated characteristics and matric suction. Based on the test results, the change of matric suction and the decrease of strength and stiffness were observed with the freezing & thawing conditions. Especially in case of the weathered soil, the strength and matric suction were significantly reduced with lower temperature and more repetition of freezing & thawing cycles. This result implies that compaction of sub-zero temperature and freezing & thawing cycles will have a considerable influence on the stability of the ground.

The Effect of Store Characteristics of a Supermarket on Store Loyalty: A Comparative Study of the Local Supermarket and the Super Supermarket (슈퍼마켓 점포속성이 점포충성도에 미치는 영향: SSM과 독립자영 SM의 비교연구)

  • Ahn, Sung-Woo;Kwon, Sung-Ku
    • Journal of Distribution Science
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    • v.10 no.11
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    • pp.61-70
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    • 2012
  • Purpose - The entry of Super Supermarkets (SSM), operated by large corporations, into the retail distribution market weakens the competitive power of local supermarkets (SM) and their families leading to a rapid collapse of the local-SM market. Accordingly, this is a very sensitive and urgent issue in Korean society and politics. Therefore, the government is required to take steps to activate a local-SM market and regain the loyalty of their customers. However, in spite of the urgent need of a comparative study on the advantages and competitive power of local-SM in relation to the SSM, little research has been done on this issue to date. One purpose of this study is to analyze the differences in store characteristics of the local SM and SSM, and to explore the relationships amongst various store characteristics, such as consumption emotion, relation quality, and store loyalty between store types to provide an efficient solution to activate a local-SM market. Research design, data, methodology - To analyze the differences in the evaluation of store characteristics between store types, and to test the moderator and mediator effects, data were collected from 488 customers in Seoul, Incheon,and Gyeonggi Province. The theoretical model consists of four hypotheses, and data was processed to test these using factor analysis, t-test, regression analysis, hierarchical regression, and the three step regression proposed by Baron and Kenny. Results - First, the analysis shows that local-SM customers evaluate location characteristic factors significantly higher compared to SSM customers. However, SSM customers evaluate quality of merchandise, sales promotion activities, and store environment significantly higher. Yet, there are no significant differences in the evaluation of consumption emotion, relation quality,and store loyalty between the store types. Second, the analysis of moderator effects of the store type show that sales promotion and store atmosphere factors have a significantly negative moderating effecton positive consumption emotion, while positive consumption emotion has a significantly positive moderating effect on absorption of relation quality, while there are no significant moderating effects between consumption emotion and store loyalty. Third, while both trust and absorption of relation quality are partially mediated between consumption emotion and store loyalty, only absorption is partially mediated between positive consumption emotion and store loyalty. There are no significant mediating effects of absorption between negative consumption emotion and store loyalty. Conclusions - We strongly recommend that location restrictions on entrance of SSM into local-SM market should either be further strengthened or sustained for the activation of the local store market. Government should strengthen financial support to improve the quality of merchandise, sales promotion, employee education, store environment of the local-SM by providing appropriate business consulting. Moreover, the result implies that the owners of alocal-SM should take measures to increase customers' absorption and store loyalty, such as store cleanliness, maintaining a delightful atmosphere at the store, and training employees on attitudes towards customers. As this study is restricted within Seoul, Incheon, and Gyeonggi Province, care needs to be taken in generalizing the interpretation and application to the national level.

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The Formation of the Ruling Ideology of the Han Dynasty and the Meaning of the Thoughts of Dongzhongshu - Focused on the relationship between the history of thought and the religious characteristic - (한조(漢朝) 통치이념의 형성과 동중서(董仲舒) 사상의 의미 - 사상사적 상호연관성과 종교성에 주목하여 -)

  • Jung, Hae-wang
    • Journal of Korean Philosophical Society
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    • v.142
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    • pp.265-294
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    • 2017
  • In the early days of human history, the governing groups of rulers needed to justify their rule. The cause of rule became the ruling ideology. In China, the backbone of the ruling ideology was originally referred to as 'Di(帝)' or 'Shangdi(上帝)', who was later replaced by 'Tian(天)', Heaven. So there was a claim that Heaven gave the cause of the rule. This idea is the 'Tianming (天命)' idea. When the Zhou(周) Dynasty took control of the central government, the 'Tianming' idea had had a relatively sophisticated form. It was the 'Zhouli(周禮)' that organized the systematic order of the Zhou Dynasty. After this system collapsed, those who recognized 'Zhouli' as a desirable social system considered the collapse of 'Zhouli' as a situation of turbulent age. It was Qin(秦) State that unified all of the states of the period. However, after the unification, the Qin Dynasty fell sharply. The next dynasty was the Han(漢) Dynasty. The new ruling powers of the Han Dynasty needed to justify their regime. That means that it was necessary to establish the ruling ideology of the Han Dynasty. The representative of the ruling ideology of the Han Dynasty was Dongzhongshu, whose thought was based on Confucianism. His thought was related to "Chunqiugongyangzhuan(春秋公羊傳)", an interpretation of "Chunqiu(春秋)". This interpretation perspective is based on the idea of religious Heaven. Dongzhongshu thought that there were co-communions between Heaven and humans. His thought has the meaning of political theology in which rulers hold the basis of the rulers' sovereignty.

A Review and Analysis of the Thermal Exposure in Large Compartment Fire Experiments

  • Gupta, Vinny;Hidalgo, Juan P.;Lange, David;Cowlard, Adam;Abecassis-Empis, Cecilia;Torero, Jose L.
    • International Journal of High-Rise Buildings
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    • v.10 no.4
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    • pp.345-364
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    • 2021
  • Developments in the understanding of fire behaviour for large open-plan spaces typical of tall buildings have been greatly outpaced by the rate at which these buildings are being constructed and their characteristics changed. Numerous high-profile fire-induced failures have highlighted the inadequacy of existing tools and standards for fire engineering when applied to highly-optimised modern tall buildings. With the continued increase in height and complexity of tall buildings, the risk to the occupants from fire-induced structural collapse increases, thus understanding the performance of complex structural systems under fire exposure is imperative. Therefore, an accurate representation of the design fire for open-plan compartments is required for the purposes of design. This will allow for knowledge-driven, quantifiable factors of safety to be used in the design of highly optimised modern tall buildings. In this paper, we review the state-of-the-art experimental research on large open-plan compartment fires from the past three decades. We have assimilated results collected from 37 large-scale compartment fire experiments of the open-plan type conducted from 1993 to 2019, covering a range of compartment and fuel characteristics. Spatial and temporal distributions of the heat fluxes imposed on compartment ceilings are estimated from the data. The complexity of the compartment fire dynamics is highlighted by the large differences in the data collected, which currently complicates the development of engineering tools based on physical models. Despite the large variability, this analysis shows that the orders of magnitude of the thermal exposure are defined by the ratio of flame spread and burnout front velocities (VS / VBO), which enables the grouping of open-plan compartment fires into three distinct modes of fire spread. Each mode is found to exhibit a characteristic order of magnitude and temporal distribution of thermal exposure. The results show that the magnitude of the thermal exposure for each mode are not consistent with existing performance-based design models, nevertheless, our analysis offers a new pathway for defining thermal exposure from realistic fire scenarios in large open-plan compartments.