• 사상체질의학회지
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• 제21권1호
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• pp.85-98
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• 2009

1. Objective The object of this study was to understand the clinical characteristics of the Taeeumin Symptomatic Pattem. 2. Methods The patients visiting the department of Sasang Constitution of Traditional Korean Medicine clinic from June to November of 2008 were used in this study. Those who showed a favorable turn after over ten days of medication and who showed up for at least two follow-up sessions were chosen among first-time visitors. Of these, 75 patients identified and verified to be of the TE type were chosen for the study sample. The Taeeumin were verified into two groups according to clinical symptoms into Exterior Cold Disease and Interior Heat Disease groups, of which the Interior Heat Disease group was further subdivided into the Galgeun-medicament group and the Cheongshimyeonja-tang group, based on questionnaire results. The Exterior Cold Disease group was set as the control group in order to contrast and compare it with the study group, the Interior Heat Disease group. 3. Results and Conclusions The questionnaire items shown to differentiate the Exterior Cold Symptomatic Patterm and the Interior Heat Symptomaic Pattern (indicating Heat-affceted Liver Symptomatic Pattern) were related to "dryness of stool," "dark urine colorm," "dryness of nose," and "dryness of lips." The items shown to differentiate the Galgeun-medicament group and the Cheongshimyeonja-tang group (of the Dry - Heat Symptomatic Pattern) were related to "nausea," "stifling sensations and palptation," "disturbed sleep," and "dizziness." Therefore, the sleep pattern, palpitation, dizziness, and nausea can be said to be indicators of the Interior Heat Symptomatic Pattern, and Dry-Heat symptoms are better distinctions between the Chongshimyeonja-tang group and the Galgeun-medicament group than Heat-affected Liver symptoms.

• 사상체질의학회지
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• 제26권3호
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• pp.251-261
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• 2014

Objectives This research was proposed to present Clinical Practice Guideline(CPG) for Soyangin Disease of Sasang Constitutional Medicine(SCM): Yin-Depletion (Mangeum) Symptomatology. The CPG was developed by the national-wide experts committee consisting of SCM professors. Methods The CPG was developed by the national-wide experts committee considering of the society of Sasang Constitutional Medicine. It was performed by search and collection of literature related SCM, opinion of SCM experts and journal search and it was followed by CPG's guideline. Results & Conclusions The CPG of Yin-Depletion (Mangeum) Symptomatology in Soyangin Disease include classification, definition and standard symptoms of each pattern. Yin-Depletion (Mangeum) Symptomatology is classified into severe and critical pattern by severity. The severe pattern of Yin-Depletion (Mangeum) Symptomatology is classified into the pattern of Heat-related diarrhea accompanied by headache (Sinyeol-dutong Mangeum) and the advanced pattern of Heat-related diarrhea accompanied by headache (Sinyeol-dutong Mangeum). The critical pattern of Yin-Depletion (Mangeum) Symptomatology is classified into the pattern of Cold-related diarrhea accompanied by the abdominal pain (Sinhan-bocktong Mangeum) and the advanced pattern of Cold-related diarrhea accompanied by abdominal pain (Sinhan-bocktong Mangeum).

• 대한한방체열의학회지
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• 제1권1호
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• pp.38-46
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• 2002

1. Objectives Among many symptoms that the climacteric patients complain of, the major subjective symptom is both heat in the upper part and cold in the lower part of the body(e.g foot, knee, and leg). We use DITI as a method to prove the symptoms of climacteric patients such as both heat in the upper part and cold in the lower part of the body, diagnose these symptoms, and follow up the progress of the clinical treatments. 2. Subjects and Methods We compare the subcutaneous heat of the climacteric patients with the symptom of heat in the upper part and cold in the lower part of the body with young women without any specific disease. The age distribution of the experimental group is 28 patients in 40's, and 22 in 50's. The mean age of the experimental group is $48.5{\pm}4.25$. The age distribution of the control group is 17 patients in teen, 26 in 20's, 7 in 30's. The mean age of the control group is $23.31{\pm}6.45$. We measure the subcutaneous heat on the cheeks, upper arms, palms, thighs, knees, dorsum pedis, lower back, hip, upper abdomen, lower abdomen of both groups and analyse the results. 3. Statistical methods All the results are statiscally analysed using student T-test of Microsoft Exel program. Statistically significant value by the analysis of variance procedure is P<0.05. 4. Results 1. The subcutaneous heat of the whole body of the experimental group shows hypothermia compared with control group, and the hypothermic pattern gets severe on the periphery. ${\Delta}T$ between the right and left side of the body in experimental group is larger than that of control group. 2. ${\Delta}T$ between the cheeks and the hypogastric in the experimental group is significantly larger than that of the control group, which shows cold face. 3. ${\Delta}T$ between the upper arms and the palms in the experimental group is significantly larger than that of the control group, which shows cold hand. 4. ${\Delta}T$ between the thighs and the knees in the experimental group is significantly larger than that of the control group, which shows cold knee. 5. ${\Delta}T$ between the thighs and the feet in the experimental group is significantly larger than that of the control group, which shows cold foot. 6. ${\Delta}T$ between the hip and the lower back in the experimental group is significantly larger than that of the control group. That shows the Lower back is warmer than the hip. 7. ${\Delta}T$ between the upper and the lower abdomen in the experimental group is significantly larger than that of the control group, which shows cold hypogastric.

• 대한한의진단학회지
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• 제19권2호
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• pp.91-100
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• 2015

Objectives The aim of this study is to develop a structured clinical protocol related with acquisition of radial pulse wave in the randomized, $2{\times}2$ cross-over design, and cold-heat intervention trial for a pilot and preliminary study. Methods The protocol was contrived based on wide ranging literature searches for cold-heat intervention experiments and radial pulse diagnoses. Results Sample size of 60 subjects was calculated based on an effect size derived from the previous study designed to detect the pre-post cold-heat differences in the radial pulse. Each subjects will be randomly assigned to the cold (first) to heat (last) group (n=30) or heat (first) to cold (last) group (n=30). All subjects will fill out a case report form and questionnaires related with pattern identification, dietary patterns, sleep quality, and physical activity will be surveyed and used as a secondary outcomes. Safety assessment will be reported at the final stage. Conclusions This protocol will provide an additional reference to future studies related with observation of radial pulse during any interventions and also expect to be used as a guideline for acquisition of reliable radial pulse wave data.

• 한국한의학연구원논문집
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• 제1권1호
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• pp.69-99
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• 1995

In order to develop experimental research in oriental medicine, it is necessary to make experimental model of diagnostic pattern(證), On model of the condition of a disease maked in china, there are cold-pattern(寒證), heat-pattern(熱證), deficiency of vital energy-pattern(氣虛證), blood-deficiency-pattern(血虛證), yin-deficiency-pattern(陰虛證), yang-deficiency-pattern(陽虛證), deficiency of both yin and yang-pattern(陰陽俱虛證), yang-exhaustion-pattern(亡陽證), blood stasis-pattern(血瘀證), pattern of defferential diagnosis according to states of viscera(臟腑辨證).

• Journal of Biosystems Engineering
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• 제33권6호
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• pp.396-403
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• 2008

Because thermal non-uniformity of transported agricultural products is mainly affected by cooling air flow pattern in the cold transport equipment, the analysis and control of flowfield is key to optimization of cold transport equipment. The objectives of this study were to estimate the effects of geometric and operating parameters of cold container on the air flow and heat transfer, and find the optimum design parameters for the low temperature level and its uniformity in given cold container with CFD simulations. Existences of ducts, gaps between pallets and geometries of exit as geometric parameters and fan blowing velocity as operating parameter were investigated. CFD simulations were carried out with the FLUENT 6.2 code. The result showed that optimum design condition was bulk loading with no duct, wall exit and 8.0 m/s of fan blowing velocity.

• 동의생리병리학회지
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• 제33권4호
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• pp.226-232
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• 2019

This study was aimed to reveal that the usual cold or heat state was associated with hypertension and could be a risk. We emailed educational personnel in D university to join this study and 182 subjects participated in from March to December in 2016. The usual cold or heat diagnosis was conducted by two experts who had over 10 years expertise. The blood pressure was measured from the subjected after 10 minute rest with Jawon medical device. The hypertension was diagnosed by the guide of the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The frequency analysis was used in general characteristics, Pearson's Correlation Coefficient analysis was conducted in among continuous variables, and chi-square test was also used between hypertension and cold or heat group. Logistic regression was analyzed to generate the odds ratios (ORs) and 95% confidence interval (CI) for hypertension. The cold score was suggested to have negative association with Body mass Index (BMI, -.374, p<.001), systolic blood pressure (-.333, p<.001), and diastolic pressure (-.261, p<.001). The heat score was analyzed to have positive association with Body mass Index (.413, p<.001), systolic blood pressure (.249, p<.001), and diastolic pressure (.156, p<.001). The distribution of the cold group (35.1%) and non-cold group (64.9%) in hypertension was significantly different (p=0.18). The distribution of the heat group (62.2%) and non-heat group (37.8%) was significantly different (p=0.27). The usual cold was associated with decreased ORs (ORs 0.405, 95% CI=0.191-0.857), and usual heat was associated with increased ORs (ORs 2.327, 95% CI=1.108-4.888). However, after adjusting body mass index, sex, and smoking, the association was not significantly different. It is possible that usual cold or heat associate with hypertension. Further study is needed to show that usual heat may be a independent risk factor for hypertension through follow up design.

• 동의생리병리학회지
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• 제26권3호
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• pp.367-375
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• 2012

The goal of current study is to make a standard pattern identification for post stroke depression using a delphi method. Finally, ten experts of oriental medicine, especially of stroke or depression, participated in Dephi examination. At the first meeting, experts conducted free discussion and determined to use the previous published questionnaires of Deficiency-Excess identification and Cold-Heat identification. From the second round, experts participated in evaluating and correcting the questionnaire by email. New seven questions were added to the questionnaire of Deficiency-Excess identification through the second round. Finally, the standard pattern identification of Cold-Heat or Deficiency-Excess is composed 20 questions and 11 questions, respectively. These pattern identifications for post stroke depression will contribute to research and treatment of oriental medicine.

• 대한예방한의학회지
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• 제14권2호
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• pp.105-120
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• 2010

Objectives : This study aims to evaluate the effects of expiration-to-inspiration time ratio (E/I-ratio) on heart rate, which represents cardiac autonomic function, and cold-heat in the healthy people. Methods : 49 healthy young volunteers(male : female = 32 : 17) were recruited in the study. The participants completed the questionnaire for yin-yang pattern identification and then we measured the chest plethysmogram for respiration signal and the electrocardiogram for NN intervals during different E/I-ratio from 1 to 2. We compared heart rate variability including RMS-SD, VLF, LF and HF, and the trend-cycle factors decomposed from NN interval data by time series analysis among the respective E/I-ratio. We also confirmed the difference on the trend-cycle factors according to the score of the questionnaire for cold and heat pattern identification. Results : There were differences on the trend-cycle factors from NN interval data, but no significant difference on heart rate variability, among the respective E/I-ratio. We also found significant relationship between the trend-cycle factors and the heat pattern identification scores. Conclusions : The results indicate that cardiac autonomic function can be modulated by the E/I-ratio and the modulation will be slower and more tendencious than respiratory sinus arrhythmia.

• 대한한의학원전학회지
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• 제18권4호통권31호
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• pp.145-154
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• 2005

The SangHanIlJeGeum(傷寒-提金) explain the six channel of disease. The Greater Yang controls the construction and defence, and governs the exterior of the body, which serves as the body's external barrier. Accordingly, many of the signs associated with greater yang appear in the early stages of disease. The essential features of greater yang disease are a pulse that is floating, headache, stiffness and pain of the head and nape, heateffusion, and aversion to cold. The main feature of Yang brightness disease is yang hyperactivity and heat exuberance. An evil can directly enter the yang brightness channel from the exterior, but it usually passes into the channel from the greater yang. Yang brightness disease is generally characterized by generalized heat effusion, spontaneous sweating, aversion not to cold but to heat, and a pulse that is large. Distinction is made between a heat patter and a repletion pattern.