• 대한한방체열의학회지
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• 제7권1호
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• pp.22-29
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• 2009

Purpose: This study intends to report the effects of Koong Gui Tang on Cold Hypersensitivity caused by acute and chronic Blood Deficiency. Methods: The patients having Cold Hypersensitivity were treated with oriental medicine including herbal medication therapy. Thereafter their health status was analyzed with their own empirical assessments and VAS. Results: After the series of medical treatment, Cold Hypersensitivity caused by acute and chronic Blood Deficiency has shown considerable improvement. Conclusion: This case study shows that Koong Gui Tang therapies are medically effective on Cold Hypersensitivity caused by acute and chronic Blood Deficiency.

• 임상간호연구
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• 제21권3호
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• pp.355-365
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• 2015

Purpose: The purpose of this study was to evaluate nursing protocols for superficial cryotherapy in different medical institutions. Methods: The study was conducted with a cross-sectional descriptive design. The medical institutions including general hospitals, hospitals, and geriatric hospitals were randomly selected. A total of 435 nurses from 126 institutions completed a questionnaire. Data were collected from December 2014 to June 2015. Results: Forty-two institutions (39.5%) had nursing protocol for cryotherapy. The nurses reported that durations of cold application were 2 minutes to 5 hours. Frequently used cold therapy devices in order of frequency were frozen gel packs, ice packs, and frozen IV fluid bags. There were variances in the duration of cold application according to the types of institution ($x^2=7.78$, p=.020) and nursing units ($x^2=26.42$, p<.001). In addition, intervals of cold application were different according to the nursing units (x=12.23, p=.032). There were differences in cold application instruments by regional groups (x=70.38, p<.001). Most of the nurses (95.6%) responded that national nursing protocol for superficial cryotherapy were needed. Conclusion: There were difficulties in providing consistent nursing interventions because of the practical differences and absence of evidence-based guidelines for cryotherapy. The researchers recommend that basic studies with various instruments be conducted and proper nursing protocols be developed for cryotherapy.

• 사상체질의학회지
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• 제21권3호
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• pp.216-222
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• 2009

1. Objectives: This case study described a process of the patient diagnosed as acute hepatitis A treated by medication based on the Sasang Constitutional Medicine and acupuctural theraphy and obtained improved effects about several symptoms. 2. Methods: We diagnosed the male patient with acute hepatitis A as Tae-Eumin Exterior-Cold-Disease by the Cold in the Esophagus, and administered Mahwangbalpyo-tang and Handayeolso-tang according to clinical progress. And we evaluated the results by liver function test(LFT; AST, ALT, $\gamma$-GTP ), total bilirubin level and the visual analog scale(VAS) of symptoms. 3. Results and Conclusion: Almost symptoms (except for jaundice) at the time of admission were disappeared, and also jaundice (estimated by color of scleras and color of urine) was alleviated. Also level of AST, ALT, $\gamma$-GTP and total bilirubin decreased in laboratory test. We obtained positive effects to the therapy but we considered necessities of further comparative studies with control group.

• The Korean Journal of Physiology and Pharmacology
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• 제25권5호
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• pp.489-494
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• 2021

Oxaliplatin, a third-generation platinum derivative, is the mainstay of current antineoplastic medications for advanced colorectal cancer therapy. However, peripheral neuropathic complications, especially cold allodynia, undermine the life-prolonging outcome of this anti-cancer agent. Rosavin, a phenylpropanoid derived originally from Rhodiola rosea, exhibits a wide range of therapeutic properties. The present study explored whether and how rosavin alleviates oxaliplatin-induced cold hypersensitivity in mice. In the acetone drop test, cold allodynia behavior was observed from days 3 to 5 after a single injection of oxaliplatin (6 mg/kg, i.p.). Cold allodynia was significantly attenuated following rosavin treatment (10 mg/kg, i.p.). Specific endogenous 5-HT depletion by three consecutive pretreatments with parachlorophenylalanine (150 mg/kg/day, i.p.) abolished the analgesic action of rosavin; this effect was not observed following pretreatment with naloxone (opioid receptor antagonist, 10 mg/kg, i.p.). Furthermore, 5-HT_1A receptor antagonist WAY-100635 (0.16 mg/kg, i.p.), but not 5-HT₃ receptor antagonist MDL-72222 (1 mg/kg, i.p.), blocked rosavin-induced analgesia. These results suggest that rosavin may provide a novel approach to alleviate oxaliplatin-induced cold allodynia by recruiting the activity of 5-HT_1A receptors.

• 대한한방부인과학회지
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• 제22권2호
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• pp.222-230
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• 2009

Purpose: This study intends to report the effects of Koong Gui Tang on Cold Hypersensitivity caused by acute and chronic Blood Deficiency. Methods: The patients having Cold Hypersensitivity were treated with oriental medicine including herbal medication therapy. Thereafter their health status was analyzed with their own empirical assessments and VAS. Results: After the series of medical treatment, Cold Hypersensitivity caused by acute and chronic Blood Deficiency has shown considerable improvement. Conclusion: This case study shows that Koong Gui Tang therapies are medically effective on Cold Hypersensitivity caused by acute and chronic Blood Deficiency.

• Journal of Acupuncture Research
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• 제20권1호
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• pp.61-73
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• 2003

Objective: The purpose of this study is to compare Sa-Am's Ohaeng-acupuncture(舍巖五行鍼法) with Linqi-aupuncture(六氣鍼法)-the transforms of Sa-Am's Ohaeng-acupuncture. Methods : Zheng Ge(正格), Sheng(勝格), Han Ge(寒格), Re Ge(熱格) of Sa-Am's Ohaeng-acupuncture compared with Liuqi-acupuncture(六氣鍼法)-therapy form invigoration and purgation of five zang-fu's wind. heat, dapness, dryness and cold(風熱濕燥寒). Results: 1. Liuqi-acupuncture used five-su points(五兪穴) and Zi-Ta Jing Bu Xie(自他經補瀉). 2. Liuqi-acupuncture is reinforced or reduced itself-point of itself-meridian(自經自穴) in therapy for invigoration and purgation. 3. Liuqi-acupuncture is therapy for invigoration and purgation of five zang-fu's wind, hear, dampness, dryness and cold(風熱濕燥寒). 4. Zheng Ge is similar to Bu-fa, Sheng Ge is similar to Xie-fa in Qu-xue of Ta-jing. The Qu-xue of interrestraining relations is the same, but that of interdependent relation is the difference in Qu-xure of Zi-jing. 5. Han Ge and Re Ge is similar to Re Bu Xie fa in Qu-xue fo Zi-jing but is different to in Ta-zing. For example, Han Ge is Shaofu(Bu), Yingu(Xie) but Re Ge is Shaofu(Xie), Yingu(Bu).

• The Journal of Korean Physical Therapy
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• 제22권1호
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• pp.67-73
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• 2010

Purpose: We tested whether repetitive transcranial magnetic stimulation (rTMS) improved recovery following spinal cord injury (SCI) in rats with transplantation of adipose tissue-derived stromal cells (ATSCs). Methods: Twenty Sprague-Dawley rats (200-250 g, female) were used. Moderate spinal cord injury was induced at the T9 level by a New York University (NYU) impactor. The rat ATSCs (approximately $5{\times}10^5$ cells) were injected into the perilesional area at 9 days after SCI. Starting four days after transplantation, rTMS (25 Hz, 0.1 Tesla, pulse width=$370{\mu}s$, on/off time=3 sec/3 sec) was applied daily for 7 weeks. Functional recovery was assessed using the Basso, Beattie, and Bresnahan (BBB) locomotor rating scale as well as pain responses for thermal and cold stimuli. Results: Both groups showed similar, gradual improvement of locomotor function. rTMS stimulation decreased thermal and cold hyperalgesia after 7 weeks, but sham stimulation did not. Conclusion: rTMS after transplantation of ATSCs in an SCI model may reduce thermal hyperalgesia and cold allodynia, and may be an adjuvant therapeutic tool for pain control after stem cell therapy in SCI.

• The Journal of Korean Physical Therapy
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• 제18권6호
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• pp.1-11
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• 2006

연구목적: 이 연구는 피부표면 냉각이 생체내의 건구조 점탄성 특성에 미치는 영향을 비교하였다. 방법: 7명의 남성 실험 대상자는 족저굴곡 운동을 10회$\times$10set, 60초 간격으로 최대 수의적 수축을 6초간 각각 실시하였다. 각 측정 전후에 내측 비복근(MG)의 건과 건막의 신장은 초음파 검사법에 의하여 직접 측정되었다(건 장력과 건 신장의 관계로 평가 되었다). 건 횡단면적과 족 관절 모멘트 암은 자기공명영상법(MRI)으로부터 얻어졌다. 건 장력은 관절 모멘트와 건 모멘트 암으로 계산되었다. 또한 스트레스는 횡단면적영역(CSA)을 힘으로 나눔으로써 얻어졌다. 스트레인은 건의 길이로 표준화된 치환으로부터 측정되었다. 결과: 냉각 후에 건 장력은, 비냉각 보다 냉각한 측이 유의하게 높았다. 스티프네스는 비냉각 조건 보다 냉각 조건하에서 높은 유의수준을 나타냈다. 최대의 스트레인과 스트레스는 냉각조건하에서 $7.4{\pm}0.7$와 $36.4{\pm}1.8$ MPa을 나타냈고, 비냉각 조건하가 $7.8{\pm}8.5$ 와 $31.8{\pm}1.1$ MPa (p<0.05)을 나타냈다. 결론: 이 연구의 결과는 피부표면 냉각으로 인해 인간의 근지구력이 건 스티프네스와 탄성률을 증가시키는 것을 시사하는 연구라 하겠다. 피부 표면 냉각으로 인한 근지구력의 개선이 근과 건에 직접적인 영향을 미침을 나타내주고 있다.

• 대한한방소아과학회지
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• 제16권1호
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• pp.133-148
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• 2002

Objective : This study was to investigate more effective oriental medical treatment for Pediatric Bronchial Asthma Method : Aroma therapy and Herbal medicine was given to 28 pediatric bronchial asthma patients(19 males and 9 females) for about 5months from the First, August 1999 The Fifth, January 2002. Results: 1. Demographic factor : The sample consisted of 28 persons among whom 19 were male, 9 were female. The age ranges from 1 year old to 6 year old. Less than 2 year old were 4 and 2-6 year old were 20. 2.Residence : Apartment and villar dwellers were 19(67.9%), Residential street divellers were 9(32.1%). 3.Age distribution at on set : 6(21.4%) fell ill befor 1 year old and 22(78.6%) fell ill after 1 year old 4. The period of illness : 9(32.2%) suffered during 1-3 year and 6(21.4%) suffered during 6 mouth-1year and 6(21.4%) suffered during more than 3 year. 5. Frequency of the symptoms : The symptoms appeared 2-3 times a year in the case of 16(57.2%), one time a year in the case of 1, 4 times a year in the case of 6(21.4%). 6. Concomitance symptoms : All experienced coughing sign, wheezing, 23(82.1%) experienced epistaxis, nose dripping, 13(46.4%) got fever, anorexia. 7. Past history of illness : 16(57.1%) got brochiolitis, brochitis, 12(42.9%) suffered pneumonia, 9(32.1%) had allergic rhinitis. 2 had allergic rhinitis, sinusitis, atopic dermatitis, bronchial asthma, 3 got atopic dermatitis, bronchial asthma and 7 had allergic rhinitis, sinusitis, bronchial asthma, 8. Family disease : In the case of family disease, 21(75%) had allergic dermatitis, 9(42.9%) had bronchial asthma, 8(38.1%) had allergic dermatitis. 9. The symptoms became very severe in the change of season in the case of 13(46.4%) and in the case of 11(39.3%), the change of season made no difference 10. Associated caused of induction symtoms : 28(100%) got sick by common cold, infectional disease, 8(28.6%) got sick by cold food, cold air 11.The kind of therapy : 15(53.6%) got oriental therapy after occidental therapy, 11(39.3%) took only oriental therapy. 12. Improvement degree of each symptoms : In the case of cough and wheeze that are the main symptoms of bronchial asthma, 78.6% and 64.3% of the patients replied < improvement > and in the case of dyspnea, tachypnea 41.7% of the patients replied . In other symptoms, all replied 13. Degree of satisfaction : 19(67.9%) replied , 2(7.1%) replied . Conclusion : Herbal medicine and aroma therapy proved to be a very effective oriental medical treatment for pediatric bronchial asthma.

• 대한한방내과학회지
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• 제21권1호
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• pp.169-180
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• 2000

Objectives : To satisfy the demand of good treatment of constipation Methods : we investigated the literatures of Oriental Medicine about Constipation. Results: 1. There are three categories of etimological factors of constipation, that is, endogenous, exogenous and non-exo-endogenous factor. The endogenous factor is caused by seven emotions, called depression of Ki and stagnation of Ki. The exogenous factor is six excessive atmospheric influences, for example, wind, cold, dampness, heat and dryness. And the non-exo-endogenous factors are overfatigue, improper diet, stagnated blood and deficiency of Ki and blood that comes from old age, long disease and after delivery. 2. Classification: According to cause of disease it is classified by constipation due to cold, heat, wind, dryness, retention of undigested and phlegm. According to Internal Organs there are constipation due to deficiency syndrome of the stomach, excess syndrome of the stomach, deficiency syndrome of kidney and splenic constipation. And Differentiation of syndromes according to Ki and blood, there are constipation of deficiency type and excess type. There are constipation due to stagnation and deficiency of Ki, deficiency of blood and stagnated blood. 3. Principles and Methods of treatment 1) Herbal Medicine (1) Excess type [1] Constipation due to heat : Seunggitang(承氣湯) and Majainwhan(麻子仁丸) [2] Constipation due to stagnation of Ki : Samatang(四磨湯) and Yukmatang(六磨湯) (2) Deficiency type [1] Constipation due to deficiency of Ki : Whanggitang(黃?湯) [2] Constipation due to deficiency of blood: Yunjangwhan(潤腸丸) [3] Constipation due to cold : Jechunjun(濟川煎) and Banyuwhan(半硫丸) 2) Enema therapy: It is a method to induce defecation by honey or pig's bile juice for weak people. 3) Acupuncture and Moxibustion: Acupoints used to treat constipation are BL25, ST25 and TE6. Moxibustion at CV8, CV6 is good for constipation due to cold. (4) Diet therapy: It is very important that we eat meals regularly and defecate on the same time even if you don't. And we have to eat food like fruits, vegetables and beans. (5) finger pressure: Finger pressing around these points like ST25, SP25, BL25, BL31, BL32, BL33 and BL34 is good for it. (6) Kigong therapy: Abdominal breathing (7) Old man' s constipation: Hip bath or diet therapy is commended. Laxation with lubricant like Supungyunjangwhan(搜風潤腸丸) is used. (8) Women' s constipation: After delivery, we have to administer tonifying prescription Sipjundaebotang(十全大補湯) and enema can be used. Conclusion : We have to examine the cause of disease and bowl movement carefully. After comprehensive analysis of the data gained by the four methods of diagnosis, we diagnose and treat patients on the base of overall of symptoms and signs.