• Title/Summary/Keyword: cognitive enhancement

검색결과 156건 처리시간 0.089초

A Meta-Analytic Review of Effects of Brain-Based Education (뇌기반 교육의 효과에 대한 메타분석)

  • Jang, Hwan Young;Jang, Bong Seok
    • Journal of Practical Engineering Education
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    • 제12권1호
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    • pp.41-47
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    • 2020
  • This study aims to investigate effects of brain-based learning. 27 primary studies were selected through rigorous search process and analyzed through meta-analytic methods. Research findings are as follows. First, the total effect size was .67. Second, the effect of dependent variables was academic achievement, cognitive domain, and affective domain in order. Third, with respect to types of cognitive domain, the effect was self-regulation, creativity, competence, communication, and research ability in order. Fourth, the effect of affective domains was sociality, learning interest, and subject attitude in order. Fifth, regarding development of cognitive ability, the effect size was combined, brain training, learning environments, and right brain activities in order. Sixth, the effect of learning activities was memory improvement and attention enhancement in order.

Hippocampus-dependent cognitive enhancement induced by systemic gintonin administration

  • Kim, Sungmin;Kim, Min-Soo;Park, Kwanghoon;Kim, Hyeon-Joong;Jung, Seok-Won;Nah, Seung-Yeol;Han, Jung-Soo;Chung, ChiHye
    • Journal of Ginseng Research
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    • 제40권1호
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    • pp.55-61
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    • 2016
  • Background: A number of neurological and neurodegenerative diseases share impaired cognition as a common symptom. Therefore, the development of clinically applicable therapies to enhance cognition has yielded significant interest. Previously, we have shown that activation of lysophosphatidic acid receptors (LPARs) via gintonin application potentiates synaptic transmission by the blockade of $K^+$ channels in the mature hippocampus. However, whether gintonin may exert any beneficial impact directly on cognition at the neural circuitry level and the behavioral level has not been investigated. Methods: In the current study, we took advantage of gintonin, a novel LPAR agonist, to investigate the effect of gintonin-mediated LPAR activation on cognitive performances. Hippocampus-dependent fear memory test, synaptic plasticity in the hippocampal brain slices, and quantitative analysis on synaptic plasticity-related proteins were used. Results: Daily oral administration of gintonin for 1 wk significantly improved fear memory retention in the contextual fear-conditioning test in mice.We also found that oral administration of gintonin for 1 wk increased the expression of learning and memory-related proteins such as phosphorylated cyclic adenosine monophosphate-response element binding (CREB) protein and brain-derived neurotrophic factor (BDNF). In addition, prolonged gintonin administration enhanced long-term potentiation in the hippocampus. Conclusion: Our observations suggest that the systemic gintonin administration could successfully improve contextual memory formation at the molecular and synaptic levels as well as the behavioral level. Therefore, oral administration of gintonin may serve as an effective noninvasive, nonsurgical method of enhancing cognitive functions.

Performance of Overlay Cognitive Radio NOMA Systems with Selected Relay for Non-licensed Receiver (비면허 수신기를 위한 선택 릴레이를 갖는 오버레이 상황인지 NOMA 시스템의 성능)

  • Kim, Nam-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • 제19권5호
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    • pp.39-45
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    • 2019
  • Recently, Cognitive radio (CR) has been focused for the effective utilization of the limited spectrum. Since an overlay CR system shares the given spectrum with the unlicensed system simultaneously, its spectral efficiency is high. However, most of the studies on an overlay CR system have been focused on the performance enhancement of the licensed receiver (LR). Correspondingly, the performance of the unlicensed receiver (UR) is degraded. Therefore, we propose an overlay CR NOMA system to improve the performance both of the LR and UR, which has a selected relay for the UR and adjusts the power allocation for the LR. The analytical performance of the proposed system is derived and verified the results through simulation. It is noticed that the UR can be obtained signal-to-noise ratio (SNR) gains by the selected relay, consequently, the system performance can be improved. Also, we show that the performance of the proposed system can be controlled by the number of the relays as well as the power allocation ratio. The results reveal that the required performance of the system can be satisfied with the use of the selected relay under the limited transmit power.

Whole body hypoxic preconditioning-mediated multiorgan protection in db/db mice via nitric oxide-BDNF-GSK-3β-Nrf2 signaling pathway

  • Li, Yuefang;Huang, Yan;Cheng, Xi;He, Youjun;Hu, Xin
    • The Korean Journal of Physiology and Pharmacology
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    • 제25권4호
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    • pp.281-296
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    • 2021
  • The beneficial effects of hypoxic preconditioning are abolished in the diabetes. The present study was designed to investigate the protective effects and mechanisms of repeated episodes of whole body hypoxic preconditioning (WBHP) in db/db mice. The protective effects of preconditioning were explored on diabetes-induced vascular dysfunction, cognitive impairment and ischemia-reperfusion (IR)-induced increase in myocardial injury. Sixteen-week old db/db (diabetic) and C57BL/6 (non-diabetic) mice were employed. There was a significant impairment in cognitive function (Morris Water Maze test), endothelial function (acetylcholine-induced relaxation in aortic rings) and a significant increase in IR-induced heart injury (Langendorff apparatus) in db/db mice. WBHP stimulus was given by exposing mice to four alternate cycles of low (8%) and normal air O2 for 10 min each. A single episode of WBHP failed to produce protection; however, two and three episodes of WBHP significantly produced beneficial effects on the heart, brain and blood vessels. There was a significant increase in the levels of brain-derived neurotrophic factor (BDNF) and nitric oxide (NO) in response to 3 episodes of WBHP. Moreover, pretreatment with the BDNF receptor, TrkB antagonist (ANA-12) and NO synthase inhibitor (L-NAME) attenuated the protective effects imparted by three episodes of WBHP. These pharmacological agents abolished WBHP-induced restoration of p-GSK-3β/GSK-3β ratio and Nrf2 levels in IR-subjected hearts. It is concluded that repeated episodes of WHBP attenuate cognitive impairment, vascular dysfunction and enhancement in IR-induced myocardial injury in diabetic mice be due to increase in NO and BDNF levels that may eventually activate GSK-3β and Nrf2 signaling pathway to confer protection.

Effects of a Single Session of Brain Yoga on Brain-Derived Neurotrophic Factor and Cognitive Short-Term Memory in Men Aged 20-29 Years

  • Yang, Hyun-Seong;Kim, Hyun-Jun;Lee, Hwa-Gyeong
    • Journal of The Korean Society of Integrative Medicine
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    • 제9권4호
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    • pp.91-103
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    • 2021
  • Purpose : This study aimed to evaluate the effects of a cognitive enhancement brain yoga program on short-term memory and serum brain-derived neurotrophic factor (BDNF) levels according to the cognitive state in men aged 20-29 years. Methods : Thirty healthy volunteers aged 20-29 years were divided into four groups: brain yoga group, yoga group, combined exercise group, and control group. Seven people were assigned randomly per group. A single-session intervention was conducted over 50 min and consisted of three parts: warm-up, main exercise (brain yoga, yoga, combined exercise, or non-exercise), and cool-down. Serum BDNF levels were measured using enzyme-linked immunosorbent assay, and short-term memory was evaluated using the forward number span test before and after the intervention. Results : BDNF levels significantly increased within the brain yoga group after the intervention (from 28874.37±5185.57 to 34074.80±7321.12, p=.003), whereas there were no significant differences pre-and post-intervention in the other groups. The inter-group comparison showed a significant interaction between the brain yoga group and the combined exercise group (p=.036) but no significant interaction between any of the other groups. Forward number span scores were significantly increased in the brain yoga group (from 9.43±9.83 to 23±7.92, p=.012) and theyoga group after the intervention (from 13.43±9.41 to 24.14±8.45, p=.011), whereas there were no significant changes after the intervention in any other groups. Conclusion : Our findings showed that a single-session, 50-minute brain yoga exercise improved short-term memory and increased serum BDNF levels in healthy men aged 20-29 years and that yoga improved only short-term memory in healthy men of this age group.

Connection Admission Control Using RA Based Dynamic Spectrum Hole Grouping in Multi-classes Cognitive Radio Networks (다중 클래스 인지 라디오 망에서 RA기반 동적 스펙트럼 홀 그룹핑에 의한 연결 수락 제어)

  • Lee, Jin-yi
    • Journal of Advanced Navigation Technology
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    • 제26권4호
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    • pp.219-225
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    • 2022
  • In this paper, we propose a CAC exploring a RA based dynamic spectrum hole grouping for secondary users' QoS enhancement in multi-classes cognitive radio networks. The RA based dynamic spectrum hole grouping uses SU multi-classes overlaying spectrum structure suggested here. Multiclass SUs are divided into real and non real, and real SUs have a priority for resource utilization against non real. The amount of resource required by real SUs is supported by Wiener prediction and the dynamic spectrum hole grouping, and that required by non real SU is supported by the remained available amount without prediction. In the simulations, we compare the proposed CAC performances using the dynamic spectrum hole grouping in terms of SU connection's blocking(dropping) rate and resource utilization efficiency according to multi-classes traffic characteristics, and then we show the proposed CAC can guarantee the desired QoS of multi-classes secondary users.

Effect of Task-oriented Training on Cognitive Function Recovery and CNS Plasticity in Scopolamine-induced Dementia Rats (치매모델 쥐의 과제지향 훈련이 인지기능 회복과 중추신경계 가소성에 미치는 영향)

  • Kim, Souk-Boum;Kim, Dong-Hyun
    • The Journal of Korean society of community based occupational therapy
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    • 제9권2호
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    • pp.23-31
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    • 2019
  • Objective : The purpose of this study is to repeatedly conduct task-oriented training in scopolamine-induced dementia rats and as a result observe changes in the content of acetylcholine, a marker of cognitive function and central nervous system plasticity, to identify the improvement effect of dementia. Methods : It consisted of two groups. One group I was that did not perform task-oriented training in scopolamine-induced dementia rats and the other group II was that performed task-oriented training. Task-oriented training involved stretching, grasping and moving arms and walking obstacles on the legs. We performed a quantified passive avoidance test in the measurement of memory for cognitive function and compared the change in the content of acetylcholine for the plasticity of the central nervous system. Results : The results of the study are as follows: First, there was a significant improvement in cognitive function since the 4th days after task-oriented training of scopolamine-induced dementia rats(.00). Second, task-oriented training applied to scopolamine-induced dementia rats showed a significant increase in acetylcholine content. Conclusion : In this study, task-oriented training, which is often performed on senile dementia patients during occupational therapy intervention, was scientifically demonstrated in scopolamine-induced dementia rats by enhancement of cognitive function through memory improvement and increase in the content of acetylcholine confirming central nervous system plasticity.

The Effects of Repeated Pain Measurement to Injury Pictures on Cognitive and Affective Empathy in Medical Students (통증사진에 대한 반복적 통증평가가 의대생의 인지적 공감과 정서적 공감에 미치는 영향)

  • Lee, Sang-Kwon;Chun, Kyung-Ju;Chang, Chulhun L.;Kim, Sung-Soo
    • The Journal of the Korea Contents Association
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    • 제17권1호
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    • pp.402-411
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    • 2017
  • To develop a more efficient computer-based empathy program that enables medical students to increase their empathy levels, and to test its applicability to medical students. We developed PACP (the Pain Assessment Computer Program) for measurement of medical students' levels of recognition of another's pain. An empathy questionnaire was administered to 145 medical students before and after the PACP. In the high empathy group, the scores for cognitive empathy increased significantly after completion of the PACP, while affective empathy scores showed no significant change. In contrast, in the low empathy group, both cognitive and affective empathy scores increased significantly after the PACP. The PACP effectively increased cognitive empathy for the high empathy group, and increased both cognitive and affective empathy, particularly for the low empathy group. Given the fact that existing empathy education programs are time-consuming and costly, and the demand for more efficient empathy education is high, the PACP as a useful tool can be applicable to medical students, particularly those with low empathy in order to enhance their empathic abilities within a short period of time.

An Impact of Empathy on the Job Satisfaction and Turnover Intention - Focused on the Mediating Effect of Job Stress - (조직구성원의 공감이 직무만족과 이직의도에 미치는 영향 - 직무스트레스의 매개효과 -)

  • Choi, Su-Heyong
    • Management & Information Systems Review
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    • 제35권4호
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    • pp.229-250
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    • 2016
  • This research was conducted to examine the effects of cognitive and emotional empathy amongst employees, and its contribution to the enhancement of the effectiveness of an organization. Further, 'job stress' was used as the moderating value. For this purpose, examination procedures were based on theoretical ground drawn from previous research papers, and an appropriate hypothesis established. Statistical methods were also employed to obtain empirical evidence. This study consisted of four variables. The independent variable is categorised into the factors of cognitive and emotional empathy. Job stress as the moderating value as well as job satisfaction and turnover intention as members of the dependent variable. A survey was carried out targeting employees of numerous firms working in teams, and a total of 324 samples were collected and processed by the software package SPSS 21 for windows as a means to verify the set study model and hypothesis. The results of the study are as follows: The two factor of cognitive and emotional empathy did not present with any significant effects. However, cognitive empathy in relation to job stress was found to inflict negative effects. The study also found the two factors to play a significant role in asserting positive effects on an individual's level of satisfaction on his/her job. While the study further explained that cognitive understanding had the tendency to impose negative effects on the turnover intention, emotional empathy did not demonstrate significant effects. Job related stress negatively effects the level of satisfaction of an individual's given task or a job and positive relation with turnover intention. It was confirmed that job stress had a degree of intermediary role upon other factors such as empathy, job satisfaction and turnover intention. The results of the study purported that empathy can raise the level of an individual's job satisfaction and kerb turnover intention. In order to accomplish depreciated levels of job related stress, it is vital that firms consistently input fervent endeavours to be subserved. It must be able to create an environment wherein employees may enjoy the improved structure of the company to empathies with each other. These transitions would allow firms to achieve maximum efficiency and improvements on the effectiveness of an organization.

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Bibliometric analysis of source memory in human episodic memory research (계량서지학 방법론을 활용한 출처기억 연구분석: 인간 일화기억 연구를 중심으로)

  • Bak, Yunjin;Yu, Sumin;Nah, Yoonjin;Han, Sanghoon
    • Korean Journal of Cognitive Science
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    • 제33권1호
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    • pp.23-50
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    • 2022
  • Source memory is a cognitive process that combines the representation of the origin of the episodic experience with an item. By studying this daily process, researchers have made fundamental discoveries that make up the foundation of brain and behavior research, such as executive function and binding. In this paper, we review and conduct a bibliometric analysis on source memory papers published from 1989 to 2020. This review is based on keyword co-occurrence networks and author citation networks, providing an in-depth overview of the development of source memory research and future directions. This bibliometric analysis discovers a change in the research trends: while research prior to 2010 focused on individuality of source memory as a cognitive function, more recent papers focus more on the implication of source memory as it pertains to connectivity between disparate brain regions and to social neuroscience. Keyword network analysis shows that aging and executive function are continued topics of interest, although frameworks in which they are viewed have shifted to include developmental psychology and meta memory. The use of theories and models provided by source memory research seem essential for the future development of cognitive enhancement tools within and outside of the field of Psychology.