• BMB Reports
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• 제54권8호
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• pp.393-402
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• 2021

In animals, proper locomotion is crucial to find mates and foods and avoid predators or dangers. Multiple sensory systems detect external and internal cues and integrate them to modulate motor outputs. Proprioception is the internal sense of body position, and proprioceptive control of locomotion is essential to generate and maintain precise patterns of movement or gaits. This proprioceptive feedback system is conserved in many animal species and is mediated by stretch-sensitive receptors called proprioceptors. Recent studies have identified multiple proprioceptive neurons and proprioceptors and their roles in the locomotion of various model organisms. In this review we describe molecular and neuronal mechanisms underlying proprioceptive feedback systems in C. elegans, Drosophila, and mice.

• 생물정신의학
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• 제25권1호
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• pp.9-15
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• 2018

Objectives This study intended to identify the deficits of cognitive control among patients with bipolar I disorder and their first-degree relatives, and identify the possibility of cognitive control as an endophenotype of bipolar disorder. Methods The study included three groups: euthymic states patients with bipolar I disorder (n = 55), unaffected first-degree relatives of probands with bipolar I disorder (n = 30), and a healthy control group (n = 51), that was matched on age, sex, and years of education. The AX version of the continuous performance test (CPT) was used to examine cognitive control. Error rate, correct response times of each subsets (AX, BX, AY, BY), and d' as an indication of accuracy sensitivity index were calculated. Psychopathology, intelligence, and psychomotor speed were also assessed. Results Patients with bipolar I disorder showed significantly worse error rates in the AX (p = 0.01) and BX (p = 0.02) subsets and d' (p = 0.05) than the others. They also showed more delayed correct response times than the healthy control group and first-degree relatives in all subsets (p < 0.01). But first-degree relatives showed neither high error rates nor delayed correct response times than healthy control group. Conclusions These findings suggest that cognitive control is impaired in bipolar I disorder but less likely to be an endophynotype of bipolar I disorder.

• 대한간호학회지
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• 제42권1호
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• pp.56-65
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• 2012

Purpose: This study was done to evaluate the effects of cognitive behavioral therapy in a victimized community district and to determine if the program is an effective nursing intervention to reduce posttraumatic stress disorder symptom, depression and state anxiety. Methods: A nonequivalent control group design was used for the study. The participants, 32 elementary school students, were selected from grades 4, 5, 6 and each student was assigned to either the experimental (16) or control (16) group. Cognitive behavioral therapy was used as the experimental treatment from April 9 to May 28, 2009. The experimental group received cognitive behavior therapy intervention 8 times. Data analysis was done using ANCOVA with SPSS 17.0. Results: After the intervention, the experimental group showed significantly lower levels of posttraumatic stress disorder symptoms than the control group. Conclusion: The findings from this study suggest that cognitive behavioral therapy is an effective nursing intervention to decrease the level of mental health problems of children in victimized district. Further research is required in order to identify the continuous effects of cognitive behavioral therapy.

• 여성건강간호학회지
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• 제13권1호
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• pp.5-12
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• 2007

Purpose: The purpose of this study was to examine the effects of cognitive intervention on myths about the uterus and anxiety in women undergoing a hysterectomy. Method: Subjects were admitted to G hospital in Busan for a hysterectomy. Of the subjects, 37 were in the experimental group and 36 were in the control group. Data was collected from December 1st, 2005 to February 28th, 2006. A hand-out, including knowledge about the uterus and the healing process, was used in the cognitive intervention. The tool for myths about the uterus had 10 questions developed by a researcher from previous research. In addition, the levels of anxiety(STAI) were measured. The data was analyzed by $x^2$-test, t-test, paired t-test, and pearson correlation coefficient with the SPSS 12.0/pc program. Results: After providing cognitive intervention, the level of belief in the myths about the uterus of the experimental group decreased significantly more than the control group. In addition, the level of anxiety of the experimental group decreased significantly more than the control group. There is a significant correlation between the myth about the uterus and anxiety. Conclusion: Cognitive intervention is a useful nursing intervention that decreases anxiety in women undergoing a hysterectomy. It is recommended to further use the appropriate cognitive intervention in nursing practice.

• 국제물리치료학회지
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• 제7권1호
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• pp.972-978
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• 2016

The purpose of this study was to identify correlations among the continence function, cognitive function, and activities of daily living(ADL) in elderly male patients with dementia in geriatric hospitals. The subjects were 64 patients aged 65 or above who were diagnosed with dementia among the hospitalized male patients in a geriatric hospital. For the subjects' cognitive function, a questionnaire developed for the Korean Mini Mental Status Examination(K-MMSE) was used. For the continence function and ADL, data were collected using a patient evaluation table. As a result, a lower level of cognitive function resulted in corresponding higher levels of dependence in all items of ADL except bathing(p<.05), and a lower level of cognitive function led to corresponding declines in the continence function(bowel control, bladder control)(p<.01). In addition, a higher level of dependence in ADL resulted in corresponding higher levels of difficulty in bowel and bladder control(p<.01). This study showed correlations among the cognitive function, ADL, and continence function of elderly men with dementia. The results of this study may be used as basic data for the management and treatment of hospitalized elderly male patients with dementia in geriatric hospitals.

• 한국보건간호학회지
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• 제32권1호
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• pp.81-95
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• 2018

Purpose: This study was conducted to identify the effects of a group cognitive improvement program on cognitive function, depression and self-esteem in elderly individuals with mild cognitive impairment. Methods: This was an experimental study that employed a pre-post design of a non-equivalence control group. The subjects were 52 elderly people with mild cognitive impairment, 25 of whom were assigned to the experimental group and 27 to the control group. The program was conducted for a total of 12 sessions for 60 minutes each. Data were analyzed using the ${\chi}2-test$, Fisher's exact test, and Independent t-test with the SPSS 20.0 program. Results: After the intervention, the group who participated showed improvement in all areas of cognitive function based on MMSE-KC (F=26.37, p.<0.001), the Rey Complex Figure Test: copy (F=20.66, p.<0.001), Immediate memory of Seoul Verbal Learning Test-Elderly's version (F=29.68, p.<0.001), delayed memory (F=45.79 p.<0.001), memory recall (F=28.97, p.<0.001), Forward of Digit Span Test (F=9.25, p=.004), backward (F=8.33, p.=0.006), language comprehension (F=13.42, p.<0.001), and digit symbol coding (F=17.74, p.<0.001) relative to the control group. Moreover depression (F=24.09, p.<0.001) was decreased in program participants, whereas self-esteem (F=40.24, p.<0.001) was increased. Conclusion: The program could be a useful intervention because the results show that the group cognitive improvement program has a significant effect on cognitive function, depression and self-esteem in elderly with mild cognitive impairment.

• 대한통합의학회지
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• 제11권1호
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• pp.53-62
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• 2023

Purpose : This study evaluated the effects of transcranial direct current stimulation and a virtual reality program on the depression, hand functions, cognitive function, and activities of daily living of patients with mild cognitive impairment by dividing 20 patients with mild cognitive impairment and depression. The 20 patients were divided into a treatment group (transcranial direct current stimulation + a virtual reality program) and a control group (placebo transcranial direct current stimulation + a placebo virtual reality program). Methods : This study allocated ten subjects to the treatment group and ten subjects to the control group. The treatment was given five times per week for six weeks (30 sessions), and each session was 30 minutes. This study screened depression by using SGDS-K, a short geriatric depression scale, to examine depression before and after treatment intervention. This study also used the box and block test, NCSE, and FIM to evaluate hand functions, cognitive function, and activities of daily living, respectively. Results : The results showed that depression significantly decreased, hand functions significantly increased, cognitive function significantly improved, and activities of daily living significantly increased after intervention in the treatment and control groups. The magnitude of changes in depression, hand functions, cognitive function, and activities of daily living was significantly different between the two groups after intervention (p>.05). Conclusion : The results showed that the application of transcranial direct current stimulation and a virtual reality program could improve cognitive function, hand functions, and activities of daily living by decreasing depression. Therefore, it can be concluded that the simultaneous application of transcranial direct current stimulation and a virtual reality program is an intervention method, which can be applied for decreasing depression, enhancing hand functions, improving cognitive function, and increasing activities of daily living in patients with mild cognitive impairment.

• 아동학회지
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• 제35권6호
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• pp.1-23
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• 2014

The purpose of this study was to develop the Cognitive Spectrum Program, a cognitive development program designed to increase children's IQ. The effect of this program was verified using a nonequivalent control group design. The subjects were 127 5-8 year old children. 56 children were assigned to the experimental group and 71 children to the control group. The experimental group participated in thirteen 90 min. long sessions. Quantitative analyses using SPSS WIN 18.0 and qualitative analyses were carried out. The results were as follows: First, this Cognitive Spectrum Program was shown to be effective in improving cognitive development. Second, the amount of improvement in cognitive development was found to be predictive of the amount of change in socioemotional development, demonstrating that attention deficits and overall problem behaviors were greatly reduced among the children whose IQ was improved by this program. This finding was also verified through qualitative analyses.

• 대한통합의학회지
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• 제8권4호
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• pp.49-58
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• 2020

Purpose : This study examined the effect of a home visit cognitive training program that uses a tablet-based digital recognition rehabilitation application, Brain Doctor, on local elderly people's cognitive function and depression. Methods : This study featured 20 elderly people living in Busan Metropolitan City, South Korea, who received a voucher for a home visit service to prevent dementia. The subjects were evenly divided into an intervention group provided with Brain Doctor and a control group provided with a conventional cognitive training program. Korean version of Mini Mental State Examination (MMSE-K) and Korean version of Montreal Cognitive Assessment (K-MoCA) were used to assess cognitive function in each group. Patient Health Questionnaire-9 (PHQ-9) was used to evaluate the depression levels. Results : The intervention group showed a significant change in cognitive function and depression after the intervention (p<.05). There was a statistically significant change in cognitive function and depression between the intervention and control groups (p<.05). Conclusion : This study confirmed that Brain Doctor had a positive effect on the cognitive function and depression of elderly people in the local community. It is expected to become a useful home visit program for dementia prevention in the future.

• 재활간호학회지
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• 제13권2호
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• pp.161-170
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• 2010

Purpose: This study was to confirm the influence of memory intensive training program on the elderly people's cognitive function, memory performance, and self-esteem. Method: Using a quasi-experimental or experimental design, 60 elderly aged over 60 years randomly assigned the experimental and control groups completed pretest-post evaluation. The experimental group participated in the memory intensive training program was offered to the participants in the experimental group for three weeks (2times/week). The t-test and $X^2$-test using SAS program. Results: 1) The cognitive function was significantly higher in the experimental group compared to that in the control group (t=3.26, p=.002). 2) The memory performance that included immediate word recall tasks, word recognition tasks and delayed word recall tasks was significantly higher in the experimental group than in the control group (t=5.30, p<.001). The experimental group showed significantly higher scores for memory performance than the control group (t=5.30, p<.001). 3) The self-esteem was higher in the experimental group than in the control group, but there was no significant difference between the two groups (t=1.94, p=.058). Conclusion: The Memory Intensive Training Program could be an effective intervention for improving cognitive function, and memory performance of the elderly people.