• Korean Journal of Adult Nursing
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• v.29 no.2
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• pp.177-189
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• 2017

Purpose: A meta-analysis was conducted to identify the effect of cognitive improvement programs for the elderly with mild cognitive impairment (MCI) in Korea. Methods: Five databases, as well as relevant reference lists, of studies published from 2000 to 2016, were searched. Fourteen studies were identified. Quality assessments of included studies were conducted using the Scottish Intercollegiate Guidelines Network checklist. An R program was used to analyze effect sizes and to identify possible sources of heterogeneity among studies. The potential for publication bias was investigated using a funnel plot, Egger's regression test and sensitivity analysis. Results: The total effect size was large (Standardized Mean Difference [SMD]=1.44, 95% CI: 1.11~1.77), with cognition based intervention (SMD= 1.77, 95% CI: 1.26~2.29) and exercise intervention (SMD=1.13, 95% CI: 0.82~1.44). Statistically significant moderators were identified intervention type by meta-ANOVA analyses. Finally, no significant evidence of publication bias was found. Conclusion: There is clear evidence that cognitive improvement programs can greatly enhance cognition in elderly with MCI. Future research should examine the effects of non-pharmacological interventions targeting elderly populations with mild-to-severe cognitive impairment in order to develop and enhance the effectiveness of cognitive improvement programs in Korea.

• Journal of KIISE:Software and Applications
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• v.36 no.6
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• pp.498-507
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• 2009

There has been insufficient studies on the effect of programming language learning on logical thinking ability. Each study result on the improvement degree and items of logical thinking ability is different according to the object of the study, its method, and the learning subject, which makes the generalization process difficult. Moreover, the necessity of programming language learning seems not proved, because it is not apparent whether the improvement of logical thinking ability is due to the advancement of knowledge or programming language learning. In this study, we instructed educational programming languages to elementary students in 6th grade for 7 hours, investigated its effect on logical-thinking ability by the meta-cognition level, and compared the result with that of computer skill learning. As a result, for Dolittle, LOGO, and Powerpoint learning groups, the logical-thinking ability of high meta-cognition level students has increased with significance, but that of low meta-cognition level students has significantly increased for Dolittle and LOGO groups only. However, regardless of meta-cognition levels, there was no significant difference of logical-thinking ability between all three groups.

• Investigative Magnetic Resonance Imaging
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• v.21 no.4
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• pp.199-209
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• 2017

Purpose: Caffeine is the most widely consumed psychostimulant. It is often adopted as a tool to modulate brain activations in fMRI studies. However, its pharmaceutical effect on task-induced deactivation has not been fully examined in fMRI. Therefore, the purpose of this study was to examine the effect of caffeine on both activation and deactivation under sustained attention. Materials and Methods: Task fMRI was acquired from 26 caffeine naive healthy volunteers before and after taking caffeine pill (200 mg). Results: Statistical analysis showed an increase in cognition-load dependent task activation but a decrease in load dependent de-activation after caffeine ingestion. Increase of attention and memory task activation and its load-dependence suggest a beneficial effect of caffeine on the brain even though it has no overt behavior improvement. The reduction of deactivation by caffeine and its load-dependence indicate reduced facilitation from task-negative networks. Conclusion: Caffeine affects brain activity in a load-dependent manner accompanied by a disassociation between task-positive network and task-negative network.

• The Korean Journal of Food And Nutrition
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• v.32 no.6
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• pp.662-668
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• 2019

The purpose of this study was to investigate effect of methanolic extracts of 10 kinds of wild vegetables cultivated in Gangwon province on antioxidant activity, acetylcholinesterase, and β-secretase inhibitory activities. Results showed that among the wild vegetables, Aralia elata(Miq.) Seem shoot extract exhibited the highest total phenol content (84.65±1.08 mg GAE/g) and total flavonoids content (70.77±0.55 mg RE/g), respectively. The antioxidant activity of wild vegetables extracts was measured by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay. Aralia elata(Miq.) Seem shoot extracts had the highest DPPH and ABTS scavenging activity (90.16%, 40.18% at 2 mg/mL). As a result, Aralia elata(Miq.) Seem shoot extract was the most effective in terms of acetylcholinesterase inhibitory activity (35.94% at 1 mg/mL). In the β-secretase activity assay, all 10 kinds wild vegetables extracts showed low inhibitory activity, and Aralia elata(Miq.) Seem shoot extract had highest inhibitory activity among the 10 wild vegetables extracts was 14.99%. Taken together, these results showed that Aralia elata(Miq.) Seem shoot extract has potential cognition improvement impact, suggesting that it may provide an effective strategy for improving cognition.

• Journal of the Korean Society of Physical Medicine
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• v.11 no.2
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• pp.115-121
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• 2016

PURPOSE: Many studies have reported the improvement of cognition through physical activity among subject with dementia. This study aimed to whether the current studies supports that physical activity intervention is efficacious on cognitive performance in subject with dementia. METHODS: Two independent reviewers searched National assembly library, RISS, KISS (2005-2015) using the concepts of dementia, exercise, and physical activity. We included randomized controlled trials that examined the efficacy of physical activity in subject with dementia. A meta-analysis was performed to estimate the effect sizes cognition with CMA (Comprehensive Meta-Analysis, version 2.2.064) soft-ware program. Nine randomized controlled trials were included, providing data from 133 individuals and excluding those failing to criteria of this study. RESULTS: The meta-analysis showed that physical activity intervention had a rather small effect sizes of 0.36 (95% confidence interval 0.14-0.59) on cognition performance in subject with dementia. Outcome measurement were MMSE-K (Mini-mental state examination Korean version) and LOCTA (Loewenstein Occupational Therapy Cognitive Assessment). We found heterogeneous among studies and there was difference between the studies (Q = 19.63, d(f)=12, $I^2= 38.88$). CONCLUSION: The present analysis suggests that physical activity interventions have the low effect sizes on cognition performance in subject with dementia Further studies will be required to develop the various programs for improving the cognitive performance in subject with dementia.

• Journal of Korean Society of Rural Planning
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• v.19 no.2
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• pp.173-181
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• 2013

The importance of human resources empowerment for operation and management is increasing for sustainable effects and improvement in mountain eco village development projects. This study aimed to understand the cognition characteristics of operator who works for mountain eco villages as part of the mountain village development and to suggest improvement methods in empowerment training aspects. The survey contained operator's empowerment and operator systems in mountain eco villages and the results were analyzed for the study. Operators who joined the mountain eco village operator training course by Korea Forest Service were conducted the survey on March 12th~13th in 2012 and March 13th~15th in 2013. 69 and 58 of questionnaires were collected respectively and analyzed for the study. T-test was applied to Intergroup cognition difference and regression analysis was used for influential factors in necessity of operator's role. Collected data was analyzed by statistical package programme SPSS 18.0 version. According to the comparison of empowerment cognition with contingent upon training experience, 'harmony with residents' showed significantly difference at p<0.05 level. In the recognition comparison for prospect of future mountain eco village development, 'various training experiences' was significantly difference at p<0.01 level between positive and negative prospect group. Regression analysis revealed that 'communication with village leader', 'harmony with residents', and 'idea related to the project' have an effect on necessity of operator's empowerment significantly. Based on the results, the study suggests improved directions for operator's empowerment training as a horizontal leader who conduces a mountain village.

• 한국노년학
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• v.37 no.2
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• pp.431-444
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• 2017

This study identified effect size of cognition improvement programs developed for normal elderly in Korea. By searching four databases, 9,624 studies published from 2000 to 2016 were identified. Finally, 14 studies which satisfied the inclusion criteria were selected for meta-analysis. Quality assessment of included studies was conducted using controlled trial checklist of Scottish Intercollegiate Guidelines Network. R version 3.3.2 (2016-10-31) with "meta" and "metafor" package was used to calculate effect sizes, identify the reasons of heterogeneity, and check publication bias. Total effect size of cognition improvement program was middle (SMD=0.759, p<.001, $I^2=34%$). For heterogeneity, moderator analysis was executed and combined program with exercise had the largest effect size (SMD=1.231, p<.001, $I^2=40.8%$). Publication bias was exist by funnel plot and Egger 's regression test, but trim and fill analysis showed that there was no serious error to reverse study results. Therefore, Combined program with exercise for the normal elderly was expected to improve the cognitive function of the normal elderly.

• 한국노년학
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• v.39 no.4
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• pp.801-824
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• 2019

As becoming an aging society, there is a rising interest on dementia. But Dementia prevention program, executed at the national level, is in insufficient state. In this study, to design and diffuse Dementia prevention program, this study conduct Cognition improvement program and evaluate cognitive function in aspects of Discrimination, Organization, Thinking, Memorizing, and Concentration capacity. So that this study try to investigate how this Cognition improvement program will affect in detail to cognitive function in senior people. This study designed Silver Cognition program for 5 aspects of cognitive function; Discrimination, Organization, Thinking, and Concentration capacity. And this studyrecruited experimental group with control group, and conducted the program to them for 3 months. At the start and the end of the program, this study evaluated their MMSE-DS score, Geriatric depression scale, Quality of life score, and cognitive function test score by survey. Finally, this study compared and analyzed these first and second score to find the effects of this program to cognitive function. As the results compared between first and second score of MMSE-DS test, Geriatric depression scale, Quality of life scale, and cognitive function test, Silver Cognition program has a significant effects to improve cognitive function, MMSE-DS score and Geriatric depression scale. As the results of the test on cognitive function in 5 aspects, cognitive function is more improved in the order of Memorizing, Thinking, Concentration, Discrimination, and Organization capacity. After the Silver Cognition program, Memorizing and Thinking capacity have most improvement. But aging of brain function is faster in these two capacity, so if more concentrated education is conducted for these two capacity, then it will bring better effects for prevention of dementia.

• Journal of Korean Society of Neurocognitive Rehabilitation
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• v.10 no.2
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• pp.9-18
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• 2018

The research has sought to examine the effect of cognition training using smart device application games on the cognition function of traumatic brain injury patients. The research was conducted to the seventeen traumatic brain injury patients with slight symptoms who were treated with occupational therapy. The patients were divided into the two groups, nine for the experimental group and eight for the control group. The experimental group was assigned to conduct cognition training using smart device application games and traditional cognition training for fifteen minutes each, and the control group has conducted the traditional cognition training for 30 minutes. All arbitrations were conducted for 30 minutes a day, five times a week and for four weeks. To assess the cognitive function, Korean Mini-Mental State Examination (K-MMSE), Lowenstein Occupational Therapy Cognitive Assessment (LOTCA) and visual memory 1 and 2 of Motor-free Visual Perception Test-3 (MVPT-3) were measured before and after the intervention. In the comparison of the change between the two groups, the experimental groups showed a significant improvement in the visual memory of Motor-free Visual Perception Test-3 and remembrance section of the Korean Mini-Mental State Examination (p<.05). The result of this research has confirmed that the cognition training using the smart device application game can make the positive change to the visual memory of the traumatic brain injury patients more than the traditional cognition training.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.3
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• pp.185-193
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• 2015

The purpose of this study was to demonstrate clinical effects on cognition, visual perception, depression, anxiety, and activities of daily living by applying the N-BACK program, a brain stimulated training program, which is used for the clinical purpose. To prove this, subjects suspected of cognitive impairment with 18-23 points in a Korean version of mental status examination (MMSE-K) were recruited among the population who had been diagnosed with stroke duration and suffered from it for six months of duration, and 10 of the subjects were selected into the experimental group and the control group, respectively. A total of 20 sessions were carried out for 30 minutes per day 5 times for 4 weeks. As a result, the experimental group who has been applied the N-BACK program showed positive results in the improvement of cognition, visual perception, depression, anxiety, and daily living skills. The results obtained from this study expect us that applying the N-BACK program for the improvement of cognition, visual perception, depression, and anxiety to stroke patients has a positive effect on the rehabilitation of patients and will lead them to improve daily living activities more independently.