• Journal of Broadcast Engineering
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• v.4 no.1
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• pp.44-58
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• 1999

In this paper, a rate-distortion based image segmentation algorithm is presented using a recursive merging with region adjacency graph (RAG). In the method, the dissimilarity between a pair of adjacent regions is represented as a Lagrangian cost function considered in rate-distortion sense. Lagrangian multiplier is estimated in each merging step, a pair of adjacent regions whose cost is minimal is searched and then the pair of regions are merged into a new region. The merging step is recursively performed until some termination criterion is reached. The proposed method thus is suitable for region-based coding or segmented-based coding. Experiment results for 256x256 Lena show that segmented-based coding using the proposed method yields PSNR improvement of about 2.5 - 3.5 dB. 0.8 -1.0 dB. 0.3 -0.6 dB over mean-difference-based method. distortion-based method, and JPEG, respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1073-1075
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• 2013

Background: In normal cells, activated epidermal growth factor receptor (EGFR) molecules are subjected to ubiquitination-mediated proteasome degradation pathway by c-Cbl, an ubiquitin ligase that checks uncontrolled proliferation. Hence expression of wild type c-Cbl molecule is essential to keep this degradation machinery in a functional state. Loss of expression or function of c-Cbl may consequently lead to sustained activation of EGFR and promote carcinogenesis, loss of function mutations in the c-Cbl gene already being reported in lung and hematopoietic cancers. However, the genetic status of c-Cbl in oral squamous cell carcinoma (OSCC) is not known. Hence in the present study we investigated the genomic DNA isolated from OSCC tissue biopsy samples for mutations in the RING finger domain coding region of c-Cbl gene, which has also been reported to be most frequently mutated in other cancers. Materials and Methods: Total genomic DNA isolated from thirty two post surgical OSCC tissue samples were amplified using primers flanking the exon 8 of c-Cbl gene that codes for the RING finger domain. The PCR amplicons were then resolved in a 1.2% agarose gel, purified and subjected to direct sequencing to screen for mutations. Results: The sequencing data of the thirty two OSCC samples did not identify mutations in the RING finger domain coding region of c-Cbl gene. Conclusions: To the best of our knowledge, this is the first time that the genetic status of c-Cbl gene in OSCC samples has been investigated. The present data indicates that genetic alteration of RING finger domain coding region of c-Cbl gene is relatively infrequent in OSCC samples.

• Journal of Korea Multimedia Society
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• v.12 no.7
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• pp.922-928
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• 2009

In H.264 as the newest video standard, 9 modes are used in order to predict the signal values of a block composed with several pixels by intra prediction. From these process, H.264 can bring high compression ratio in the encoded signal but the use of total 9 modes can give the inefficiency of the increase of the complexity induced by the amount of operation processing or the number of searching which is applied to compare adjacent pixels. This paper proposes a simplification method of prediction mode for the intra-picture coding by considering subjective interest region. There are certain region being interested within a picture of the video sequence. This region requires better subjective picture quality than the other regions. The proposed method increases the simplification of prediction mode by providing just essential modes of total 9 modes for less interest regions compared with the interest region. It is possible to get the additional 11%$\sim$15% simplification of the prediction mode by the proposed method, compared with the conventional method which simplifies the prediction mode for all of the picture by using the prediction characteristics only.

• Korean Journal of Microbiology
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• v.28 no.1
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• pp.1-5
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• 1990

The coding sequence of hepatitis B viral core antigen (HBcAg) (subtype adr) contains two in-phase initiation codons, one for precore and the other for core antigen gene. To study the expression of core antigen and the role of precore region, the coding sequence of HBcAg with or without precore (pre-C) region were subcloned into yeast expression vector containing phosphoglycerate kinase (PGK) promoter. To study the role of upstream region in the expression of the core antigen, a series of 5' deletion mutants were also subcloned into the vector. After transformation into various host strains, the expression of HBcAg were analysed by radio-immunoassat. Under optimal condition of core antigen gene expression in yeast, the highest amount of antigen was detected in the cell line SHY4 containing pGKHBc plasmid composed of the yeast PGK gene promoter, terminator and C-gene. Regardless of the presence of precore region, core antigen was not detected in the medium but in cell extract. These results suggest that precore region cannot affect the secretion of core antigen in Saccharomyces cerevisiae.

• Journal of Animal Science and Technology
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• v.49 no.6
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• pp.719-728
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• 2007

The cysteine and glycine rich protein 3 (CSRP3), apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 2(APOBEC2) and caveolin (CAV) gene family(CAV1, CAV2, CAV3) have been reported to play important roles for carcass and meat quality traits in pig, mouse, human and cattle. As an initial step, we investigated SNPs in these 5 genes among eight different cattle breeds. Eighteen primer pairs were designed from bovine sequence data of NCBI database to amplify the partial gene fragments. Sequencing results revealed 9 SNPs in the coding regions of three caveolin genes, 1 SNP in CSRP3 and 3 SNPs in APOBEC2 gene. All the identified SNPs were confirmed by PCR-RFLP. Also, 9 more intronic SNPs were detected in these genes. However, all identified mutations in the coding region do not change amino acid sequence. Allelic distributions were significantly different for 5 SNPs in CAV2, CAV3, CSRP3 and APOBEC2 genes among the eight different breeds. These results gave some clues about the polymorphisms of these genes among the cattle breeds and will be useful for further searches for identifying association between these SNPs and meat quality traits in cattle.

• Animal cells and systems
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• v.2 no.1
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• pp.113-116
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• 1998

A cDNA clone coding for ribosomal protein 46 (rp46) which is a component of 60S ribosomal large subunit has been identified from Drosophila melanogaster. A cDNA clone encoding S. cerevisiae rp46 was used as a probe to screen a Drosophila larvae cDNA library. The DNA sequence analysis revealed that the cDNA coding for Drosophils rp46 contains a complete reading frame of 153 nucleotides coding for 51 amino acids. The deduced amino acid sequence showed 71-75% homology with those of other eukaryotic organisms. Northern blot analysis showed that about 1-kb rp46 transcripts are abundant throughout fly development. Whole mount embryonic mRNA in situ hybridization also showed no preferential distribution of the transcripts to any specific region. The chromosomal in situ hybridization revealed that the identified gene is localized at position 60C on the right arm of the second polytene chromosome with a possibility of single copy.

• Phonetics and Speech Sciences
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• v.4 no.3
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• pp.119-125
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• 2012

This paper describes a new algorithm for encoding spectral shape and envelope in the generic mode of G.718 super-wide band (SWB). In the G.718 SWB coder, generic mode coding and sinusoidal enhancement are used for the quantization of modified discrete cosine transform (MDCT)-based parameters in the high frequency band. In the generic mode, the high frequency band is divided into sub-bands and for every sub-band the most similar match with the selected similarity criteria is searched from the coded and envelope normalized wideband content. In order to improve the quantization scheme in high frequency region of speech/audio signals, the modified generic mode by the improvement of the generic mode in G.718 SWB is proposed. In the proposed generic mode, perceptual vector quantization of spectral envelopes and the resolution increase for spectral copy are used. The performance of the proposed algorithm is evaluated in terms of objective quality. Experimental results show that the proposed algorithm increases the quality of sounds significantly.

• Proceedings of the Korea Contents Association Conference
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• 2004.11a
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• pp.505-510
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• 2004

This paper suggests a new CT-image segmentation algorithm. This algorithm uses morphological filters and the watershed algorithms. The proposed CT-image segmentation algorithm consists of six parts: preprocessing, image simplification, feature extraction, decision making, region merging, and postprocessing. By combining spatial and temporal information, we can get more accurate segmentation results. The simulation results illustrate not only the segmentation results of the conventional scheme but also the results of the proposed scheme; this comparison illustrates the efficacy of the proposed technique. Furthermore, we compare the various medical images of the structuring elements. Indeed, to illustrate the improvement of coding efficiency in postprocessing, we use differential chain coding for the shape coding of results.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.95-100
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• 1997

In this paper, we propose a coding method to improve compression efficiency for MR image. This can be achieved by combining coding and segmentation scheme which removes noisy background region, which is meaningless for diagnosis, in MR image. The wavelet coder encodes only diagnostically significant foreground regions refering to segmentation map. Our proposed algorithm provides about 15% of bitrate reduction when compared with the same coder which is not combined with segmentation scheme. And the proposed scheme shows better reconstructed image Qualify than JPEG at the same compression ratio.

• ETRI Journal
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• v.34 no.1
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• pp.102-105
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• 2012

To serve the growing demand of the bidirectional information exchange, we propose a single relay selection (RS) scheme for physical-layer network coding (PNC) in a bidirectional cooperative network consisting of two sources and multiple relays. This RS scheme selects a single best relay by maximizing the bottleneck of the capacity region of both information flows in the bidirectional network. We show that the proposed RS rule minimizes the outage probability and that it can be used as a performance benchmark for any RS rules with PNC. We derive a closed-form exact expression of the outage probability for the proposed RS rule and show that it achieves full diversity gain. Finally, numerical results demonstrate the validity of our analysis.