• 제목/요약/키워드: cluster randomization

검색결과 4건 처리시간 0.017초

지역사회 임상시험시 개인별 무작위배정과 군집 무작위배정의 효율성 비교 (Comparison of Efficiency between Individual Randomization and Cluster Randomization in the Field Trial)

  • 구혜원;곽민정;이영조;박병주
    • Journal of Preventive Medicine and Public Health
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    • 제33권1호
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    • pp.51-55
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    • 2000
  • Objectives . In large-scale field trials, randomization by cluster is frequently used because of the administrative convenience, a desire to reduce the effect of treatment contamination, and the need to avoid ethical issues that might of otherwise arise. Cluster randomization trials are experiments in which intact social unit, e.g., families, schools, cities, rather than independent individuals are randomly allocated to intervention groups. The positive correlation among responses of subjects from the same cluster is in matter in cluster randomization. This thesis is to compare the results of three randomization methods by standard error of estimator of treatment effect. Methods : We simulated cholesterol data varing the size of the cluster and the level of the correlation in clusters and analyzed the effect of cholesterol-lowering agent. Results : In intra-cluster randomization the standard error of the estimator of treatment effect is smallest relative to that in inter-cluster randomization and that in individual randomization. Conclusions : Infra-cluster randomization is the most efficient in its standard error of estimator of treatment effect but other factor should be considered when selecting a specific randomization method.

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Confidence Interval for the Difference or Ratio of Two Median Failure Times from Clustered Survival Data

  • Lee, Seung-Yeoun;Jung, Sin-Ho
    • 응용통계연구
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    • 제22권2호
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    • pp.355-364
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    • 2009
  • A simple method is proposed for constructing nonparametric confidence intervals for the difference or ratio of two median failure times. The method applies when clustered survival data with censoring is randomized either (I) under cluster randomization or (II) subunit randomization. This method is simple to calculate and is based on non-parametric density estimation. The proposed method is illustrated with the otology study data and HL-A antigen study data. Moreover, the simulation results are reported for practical sample sizes.

클러스터를 이용한 고성능 RC4 암호화 하드웨어 설계 (The Design of a High-Performance RC4 Cipher Hardware using Clusters)

  • 이규희
    • 한국정보통신학회논문지
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    • 제23권7호
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    • pp.875-880
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    • 2019
  • RC4 스트림 암호화는 내부 구현이 간단하고 빠르게 암호화 할 수 있는 초경량 암호화 알고리즘으로 IEEE 802.11의 WEP와 IEEE 802.11i의 TKIP 등에 널리 이용되고 있다. RC4는 IoT 등의 제한적 자원을 갖는 시스템들에도 사용되지만 성능상 제약이 있다. RC4 암호화는 S-배열과 K-배열의 초기화 및 랜덤화를 수행하는 KSA(Key Scheduling Algorithm)와 랜덤화된 S-배열을 이용하여 암호문을 생성하는 PRGA(Pseudo-Random Generation Algorithm)의 두 단계로 구성된다. 본 논문에서는 KSA에서 발생하는 초기화 지연시간을 줄이기 위해, 랜덤화 과정에 초기화를 삽입하여 함께 처리한다. KSA의 랜덤화에서 교환(swap) 작업과 PRGA의 암호문 생성은 클러스터를 이용하여 매 클록마다 두 개의 교환 및 암호문이 생성되도록 하였다. 제안된 RC4 암호화 하드웨어 구조는 초기화 지연시간이 발생하지 않으며, 랜덤화와 키 스트림 생성율에서 다른 연구들과 비교하여 약 2배에서 6배의 성능이 향상되었다.