• Title/Summary/Keyword: cluster management

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Gene Expression Patterns Associated with Peroxisome Proliferator-activated Receptor (PPAR) Signaling in the Longissimus dorsi of Hanwoo (Korean Cattle)

  • Lim, Dajeong;Chai, Han-Ha;Lee, Seung-Hwan;Cho, Yong-Min;Choi, Jung-Woo;Kim, Nam-Kuk
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.8
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    • pp.1075-1083
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    • 2015
  • Adipose tissue deposited within muscle fibers, known as intramuscular fat (IMF or marbling), is a major determinant of meat quality and thereby affects its economic value. The biological mechanisms that determine IMF content are therefore of interest. In this study, 48 genes involved in the bovine peroxisome proliferator-activated receptor signaling pathway, which is involved in lipid metabolism, were investigated to identify candidate genes associated with IMF in the longissimus dorsi of Hanwoo (Korean cattle). Ten genes, retinoid X receptor alpha, peroxisome proliferator-activated receptor gamma (PPARG), phospholipid transfer protein, stearoyl-CoA desaturase, nuclear receptor subfamily 1 group H member 3, fatty acid binding protein 3 (FABP3), carnitine palmitoyltransferase II, acyl-Coenzyme A dehydrogenase long chain (ACADL), acyl-Coenzyme A oxidase 2 branched chain, and fatty acid binding protein 4, showed significant effects with regard to IMF and were differentially expressed between the low- and high-marbled groups (p<0.05). Analysis of the gene co-expression network based on Pearson's correlation coefficients identified 10 up-regulated genes in the high-marbled group that formed a major cluster. Among these genes, the PPARG-FABP4 gene pair exhibited the strongest correlation in the network. Glycerol kinase was found to play a role in mediating activation of the differentially expressed genes. We categorized the 10 significantly differentially expressed genes into the corresponding downstream pathways and investigated the direct interactive relationships among these genes. We suggest that fatty acid oxidation is the major downstream pathway affecting IMF content. The PPARG/RXRA complex triggers activation of target genes involved in fatty acid oxidation resulting in increased triglyceride formation by ATP production. Our findings highlight candidate genes associated with the IMF content of the loin muscle of Korean cattle and provide insight into the biological mechanisms that determine adipose deposition within muscle.

The Impact of Shared Value Creation of Social Enterprise on Organizational Performance (사회적기업의 공유가치창출이 조직성과에 미치는 영향)

  • Lee, Yong-Jae;Um, So-Young
    • The Journal of the Korea Contents Association
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    • v.18 no.4
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    • pp.369-379
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    • 2018
  • The purpose of this study is to examine the impact of social enterprise's shared value creation on corporate performance and to develop policy measures to enhance competitiveness of social enterprises. The main results and implications are as follows. First, according to the general characteristics of social enterprises, the difference between shared value creation and organizational performance was not statistically significant. In other words, although the social enterprise has various organizational characteristics, it does not differ from the shared value creation or the organizational performance that it creates. The rapid increase of social enterprises led to a rapid increase in various types of social enterprises, but there is no difference between shared value creation and organizational performance. Second, the results of analyzing the impact of shared value creation on the organizational performance of social enterprises revealed that social performance was statistically significant influenced by re-recognition of product market and regional cluster among sub-factors of shared value creation. Among the sub-factors of social enterprise's economic performance, the re-recognition of the product market had a statistically significant effect on the overall organizational performance of social enterprises. Among the sub-factors of shared value creation. In the future, it will be necessary to make effort to improve corporate performance by introducing the concept of shared value creation for social enterprise and making policy efforts to activate it.

Diversity of the Gastric Microbiota in Thoroughbred Racehorses Having Gastric Ulcer

  • Dong, Hee-Jin;Ho, Hungwui;Hwang, Hyeshin;Kim, Yongbaek;Han, Janet;Lee, Inhyung;Cho, Seongbeom
    • Journal of Microbiology and Biotechnology
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    • v.26 no.4
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    • pp.763-774
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    • 2016
  • Equine gastric ulcer syndrome is one of the most frequently reported diseases in thoroughbred racehorses. Although several risk factors for the development of gastric ulcers have been widely studied, investigation of microbiological factors has been limited. In this study, the presence of Helicobacter spp. and the gastric microbial communities of thoroughbred racehorses having mild to severe gastric ulcers were investigated. Although Helicobacter spp. were not detected using culture and PCR techniques from 52 gastric biopsies and 52 fecal samples, the genomic sequences of H. pylori and H. ganmani were detected using nextgeneration sequencing techniques from 2 out of 10 representative gastric samples. The gastric microbiota of horses was mainly composed of Firmicutes (50.0%), Proteobacteria (18.7%), Bacteroidetes (14.4%), and Actinobacteria (9.7%), but the proportion of each phylum varied among samples. There was no major difference in microbial composition among samples having mild to severe gastric ulcers. Using phylogenetic analysis, three distinct clusters were observed, and one cluster differed from the other two clusters in the frequency of feeding, amount of water consumption, and type of bedding. To the best of our knowledge, this is the first study to investigate the gastric microbiota of thoroughbred racehorses having gastric ulcer and to evaluate the microbial diversity in relation to the severity of gastric ulcer and management factors. This study is important for further exploration of the gastric microbiota in racehorses and is ultimately applicable to improving animal and human health.

Development of an Informetric Analysis System KnowledgeMatrix (계량정보분석시스템 KnowledgeMatrix 개발)

  • Lee, Bangrae;Yeo, Woon Dong;Lee, June Young;Lee, Chang-Hoan;Kwon, Oh-Jin;Moon, Yeong-ho
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.167-171
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    • 2007
  • Application areas of Knowledge Discovery in Database (KDD) have been expanded into many R&D management processes including technology trends analysis, forecasting and evaluation etc. Established research field such as informetrics (or scientometrics) has recently fully utilized techniques or methods of KDD. Various systems have been developed to support works of analyzing large-scale R&D related databases such as patent DB or bibliographic DB by a few researchers or institutions. But extant systems have some problems for korean users to use. Their prices is not cheap, korean language process not available, and user's demands not reflected. To solve these problems, Korea Institute of Science and Technology Information (KISTI) developed stand-alone type information analysis system named as KnowledgeMatrix. KnowledgeMatrix system offer various functions to analyze retrieved data set from databases. Knowledge Matrix main operation unit is composed of user-defined lists and matrix generation, cluster analysis, visualization, data pre-processing. KnowledgeMatrix show better performances and offer more various functions than extant systems.

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SEARCHING MINOR PLANETS AND PHOTOMETRIC QUALITY OF 60cm REFLECTOR IN GIMHAE ASTRONOMICAL OBSERVATORY (김해천문대 60cm 반사망원경의 측광성능 분석과 소행성 탐사)

  • Lee, Sang-Hyun;Kang, Yong-Woo;Lee, Kyung-Hoon
    • Journal of Astronomy and Space Sciences
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    • v.24 no.3
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    • pp.209-218
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    • 2007
  • In this paper, we have presented the observational result for the photometric quality of main telescopes in Gimhae Astronomical Observatory. Also we performed the observation of searching new minor planets as competitive work in public observatories. The observation was carried out using 60cm telescope of Gimhae Astronomical Observatory on 2007 January 13. And, $Sch\ddot{u}ler$ BVI filters and 1K CCD camera (AP8p) were used. To define the quality of CCD photometry, we observed the region of well-known standard stars in the open cluster M67. From observed data, The transformation coefficients and airmass coefficients were obtained, and the accuracy of CCD photometry was investigated. From PSF photometry, we obtained the color-magnitude diagram of M67, and considered the useful magnitude limit and the physical properties of M67. This method can be successfully used to confirm the photometric quality of main telescope in public observatories. To investigate the detection possibility of unknown object as astroid, we observed the near area of the opposition in the ecliptic plane. And we discussed the result. Our result show that it can be possible to detect minor planets in solar system brighter than $V{\sim}18.3mag$. and it can carry out photometric study brighter than V 16mag. in Gimhae Astronomical Observatory. These results imply that the public observatories can make the research work.

Analysis of Seasonal Variation Effect of the Traffic Accidents on Freeway (고속도로 교통사고의 계절성 검증과 요인분석 (중부고속도로 사례를 중심으로))

  • 이용택;김양지;김대현;임강원
    • Journal of Korean Society of Transportation
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    • v.18 no.5
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    • pp.7-16
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    • 2000
  • This paper is focused on verifying time-space repetition of the highway accident and finding the their causes and deterrents. We classify all months into several seasonal groups, develop the model for each seasonal group and analyze the results of these models for Joong-bu highway. The existence of seasonal effect is verified by the analysis or self-organizing map and the accident indices. Agglomerative hierarchical cluster analysis which is used to decide the seasonal groups in accordance with accident patterns, winter group, spring-fall group. and summer group. The accident features of winter group are that the accident rate is high but the severity rate is low. while those of summer group are that the accident rate is low but the severity rate is high. Also, the regression model which is developed to identify the accident Pattern or each seasonal group represents that the season-related factors, such as the amount of rainfall, the amount of snowfall, days of rainfall, days of snowfall etc. are strongly related to the accident pattern of evert seasonal group and among these factors the traffic volume, amount of rainfall. the amount of snowfall and days of freezing importantly affect the local accident Pattern. So, seasonal effect should be considered to the identification of high-risk road section. the development of descriptive and Predictive accident model, the resource allocation model of accident in order to make safety management plan efficient.

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A Study on the Health Promoting Behaviors Depending on the Response Patterns of HLOC in Korean Adults (한국 성인의 건강통제위 반응유형별 건강증진행위)

  • Gu, Mee-Ock;Eun, Young
    • Journal of Korean Academy of Nursing
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    • v.28 no.3
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    • pp.739-750
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    • 1998
  • The purpose of this study was to identify the response patterns of Health Locus of Control (HLOC) and to analysis of the health promoting behaviors depending on the response patterns of HLOC in Korean adults. The sample was composed of 300 healthy adults ranged from twenties to seventies. In data analysis, SPSS PC/sup +/ program was utilized for descriptive statistics, pearson correlation, ANOVA and cluster analysis. The results of the study were as follows : 1. The average scores of HLOC in Korean were HLOC-I : 24.12(range 6-30), HLOC-P : .21.72, HLOC-C : 17.46. 2. The total mean score of the health promoting behavior scale was 2.50 (range 1-4), and the mean scores on the subscales were ; self actualization 2.60, health responsibility 2.14, exercise 2.28, nutrition 3.16, interpersonal support 2.74, stress management 2.15. 3. The HLOC-I and health promoting behavior were correlated positively(r =0.184, p=0.001), and the HLO-C and the health promoting behavior were correlated negatively(r=-0.102, p=0.039). The HLOC-P and the health promoting behavior weren't correlated in the level of statistical significance. 4. The response patterns of HLOC in Korean adults were identified 6 types, such as pure internal, pure chance, believers in control, yea sayer, nay sayer, and complex control. The type of believers in control and the type of yea sayer were subdivided in two different types. The believers in control was the largest group(33.67%), and yea sayer was the next large group(26.33%). The pure chance and the complex control type was the smallest groups. 5. There was a significant difference in health promoting behavior depending on the response patterns of HLOC(F=2.67, p=0.010). There were also significant differences in 4 subscales of health promoting behavior : self actualization(F=3.12, P=0.003), health responsibility(F=2.15, P=0.038), nutrition(F=5.08, p=0.000), and interpersonal support(F=2.26,p=0.029). These results suggest that the response patterns of HLOC is the important factor to predict the level of health promoting behavior in Korean adults.

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Implication of the Ratio of Exchangeable Cations in Mountain Wetlands (산지습지 치환성 양이온 함량비의 특성과 함의)

  • Shin, Young Ho;Kim, Sung Hwan;Rhew, Hosahang
    • Journal of the Korean Geographical Society
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    • v.49 no.2
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    • pp.221-244
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    • 2014
  • We suggested several implications by examining geochemical properties of sediments in Simjeok, Jangdo, and Hwaeomneup mountain wetlands which are natural preservation areas. Geochemical properties of wetland sediments show that all wetlands were included in the type of fens, but their distribution patterns were different from one another. We classified three sub-groups of sediments using the two step cluster analysis on the ratio of exchangeable cations. Wetland sediments can be grouped into Ca-dominated, Mg-dominated, and K-dominated types. Simjeok wetland have Ca-dominated sediments, while the sediments of Jangdo wetland indicate the Mg-dominated and Ca-dominated characteristics. Hwaeomneup wetland is composed of K-dominated sediment mainly. Different properties in the ratio are affected by various environmental factors such as geological, pedological, and vegetational settings. Because these geochemical properties will be affected by climate change and human impacts, these will be environmental indicator in mountain wetlands and be used in wetland management. This scheme can be used for classification of mountain wetlands. Therefore, we should work on geochemical properties of wetland sediments and classification schemes based on geochemical properties not only to widen understanding in geomorphic system or ecosystem of mountain wetlands but to conserve mountain wetlands properly.

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Standardization of Measurements for Korean Kitchen Work Centers and Cabinets for Future Design Criteria(IV) -Classification of Life Style Related to Kitchen Space in Contemporary Korea: as a Basis for Desirable Kitchen Type- (한국부엌의 작업대와 수납나의 표준치수설정을 위한 연구 IV -부엌과 관련된 현대 한국인의 생활양식 유형 분류-)

  • Chi, Soon;Yoon, Bok-Cha;Lee, Yeun-Sook;Yoo, Seong-Hee;Oh, Chan-Ohk;Choi, Hee-Jae;Park, Hye-Kyung;Seong, Hai-Sook
    • Journal of the Korean Home Economics Association
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    • v.25 no.3
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    • pp.63-82
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    • 1987
  • This is the forth consecutive study on the 'Standardization of Measurement for Korean Kitchen Work Centers and Cabinets for Future Design Criteria'. The purpose of the present research was (1) to classify homemakers' representative like styles related to the kitchen, (2) to examine homemakers' present concerns on the kitchen space, and (3) to investigate homemakers' desire and preference on the kitchen space. Twenty two hundred homemakers of upper and middle class residing in Seoul, Busan, Daegu, Incheon, Gwangju and Daejeon were selected for the survey and 1,843 among them were used for data analysis. Data were selected for the survey and 1,843 among them were used for data analysis. Data were analyzed using the SAS program package. The statistics used were frequency, percentage, mean, factor analysis, F-test, Duncan's multiple range test, X2-test, cluster analysis. Findings from the research as follows: (1) Four factors were found as indicaters of the life style; values on the household work, desire on social function of the kitchen, degree on cooperation of family members on the household work, and convenient management. It was noticeable that homemakers had positive responses in terms of desire on social function of the kitchen and degree on cooperation of family members on the household work. Homemakers' life styles related to the kitchen space were classified into 6 categories. (2) Relatively a few respondents answered that the kitchens were very well furnished. If, however, the economic conditions become better, substantial number of them wanted to invest for better kitchen following the one for living room. (3) It was found that most respondents preferred the arrangement of space, where dining and kitchen in one space, and a hard wall or soft treatment was between living and dining/kitchen area. (4) Many respondents desired pantry, utility and laundry area be near the kitchen or in the same space with it, thereby forming a utility core in a housing space.

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Leisure Constraints and Negotiation based on the Marital Status in Career Women (직장여성의 결혼에 따른 여가제약과 여가제약협상)

  • Kim, Hongseol;Lee, Munjin;Hwang, Sunhwan
    • The Journal of the Korea Contents Association
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    • v.15 no.1
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    • pp.242-251
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    • 2015
  • The purpose of this study was to explore leisure constraints and the strategies to overcome leisure constraints of career women, and to examine the difference in leisure constraints and leisure constraints negotiation strategies between married and unmarried career women. In Seoul, a total of 440 career women selected using the cluster quota sampling method participated in the current study. Finally, 433 responded data with the exception of 7 unreliable surveys were employed for the analyses such as frequency, exploratory factor, reliability analysis, and t-test. Main findings were as follows; First, six factors including interpersonal, intrapersonal, time, expense and information, environmental, and physical constraints were extracted for career women. Environment and time commonly constrained their participation in leisure activities the most. Second, five factors including skill acquisition, finding alternative activity, control intensity, finding partners, and financial and time management strategies were extracted for them. Third, there were the differences in time and physical constraints between two groups and married career women's constraints were higher than singles. Finally, there was the difference in skill acquisition strategy and married career women's it was higher than the other group.