• 한국전기전자재료학회논문지
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• 제21권9호
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• pp.795-800
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• 2008

A sublimation method using the SiC seed crystal and SiC powder as the source material is commonly adopted to grow SiC bulk single crystal. However, it has proved to be difficult to achieve the high quality crystal and the process reliability because SiC single crystal should be grown at very high temperature in closed system. The present research was focused to improve SiC crystal quality grown by PVT method through using the new inner guide tube. The new inner guide tube was designed to prevent the enlargement of polycrystalline region into single crystalline region and to enlarge the diameter of SiC single crystal. The 6H-SiC crystals were grown by conventional PVT process. The seed adhered on seed holder and the high purity SiC source materials are placed on opposite side in sealed graphite crucible surrounded by graphite insulation. The SiC bulk growth was conducted around 2300 $^{\circ}C$ of growth temperature and 50 mbar in an argon atmosphere of growth pressure. The axial thermal gradient across the SiC crystal during the growth was estimated in the range of 15${\sim}$20 $^{\circ}C$/cm.

• The Korean Journal of Physiology and Pharmacology
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• 제10권5호
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• pp.243-249
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• 2006

The effect of genistein, widely used as a specific tyrosine kinase inhibitor, on rat brain Kv1.5 channels which were stably expressed in Chinese hamster ovary cells was investigated using the whole-cell patch-clamp technique. Genistein inhibited Kv1.5 currents at +50 mV in a concentration-dependent manner, with an $IC_{50}$ of $54.7{\pm}8.2\;{\mu}M$ and a Hill coefficient of $1.1{\pm}0.2$. Pretreatment of Kv1.5 with protein tyrosine kinase inhibitors ($10\;{\mu}M$ lavendustin A and $100\;{\mu}M$ AG1296) and a tyrosine phosphatase inhibitor ($500\;{\mu}M$ sodium orthovanadate) did not block the inhibitory effect of genistein. The inhibition of Kv1.5 by genistein showed voltage-independence over the full activation voltage range positive to 0 mV. The activation (at +50 mV) kinetics was significantly delayed by genistein: time constant for an activation of $1.4{\pm}0.2$ msec under control conditions and $10.0{\pm}1.5$ msec in the presence of $60\;{\mu}M$ genistein. Genistein also slowed the deactivation of the tail currents, resulting in a crossover phenomenon: a time constant of $11.4{\pm}1.3$ msec and $40.0{\pm}4.2$ msec under control conditions and in the presence of $60\;{\mu}M$ genistein, respectively. Inhibition was reversed by the application of repetitive depolarizing pulses, especially during the early part of the activating pulse. These results suggest that genistein directly inhibits Kv1.5 channels, independent of phosphotyrosine-signaling pathway.

• The Korean Journal of Physiology and Pharmacology
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• 제4권1호
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• pp.25-31
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• 2000

ATP-sensitive potassium channels ($K_{ATP}$ channels) play an important role in insulin secretion from pancreatic beta cells. We have investigated the effect of propofol on $K_{ATP}$ channels in cultured single pancreatic beta cells of rats. Channel activity was recorded from membrane patches using the patch-clamp technique. In the inside-out configuration bath-applied propofol inhibited the $K_{ATP}$ channel activities in a dose-dependent manner. The half-maximal inhibition dose (ED50) was $48.6{\pm}8.4\;{\mu}M$ and the Hill coefficient was $0.73{\pm}0.11.$ Single channel conductance calculated from the slope of the relationship between single channel current and pipette potential $(+20{\sim}+100\;mV)$ was not significantly altered by propofol $(control:\;60.0{\pm}2.7\;pS,\;0.1\;mM\;propofol:\;58.7{\pm}3.5\;pS).$ However, mean closed time was surely increased. Above results indicate that propofol blocks the $K_{ATP}$ channels in the pancreatic beta cells in the range of its blood concentrations during anesthesia, suggesting a possible effect on insulin secretion and blood glucose level.

• Archives of Plastic Surgery
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• 제32권5호
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• pp.555-560
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• 2005

The nose is shaped as a pyramid and is the most prominent portion of the face. Nasal bone fractures are thus more frequent than those of the maxilla and zygoma. Whether the nasal bone fractures are corrected or not due to unnecessity of surgical treatment, the incidence of posttraumatic deformity occurs frequently. In Asian patients, even the corrected noses look low-lying and flat. To resolve these problems, we corrected the posttraumatic deformity of the nose with a combined procedure of nasal ostectomy and augmentation rhinoplasty. From 2000 to 2004, this procedure was performed in fifteen patients with posttraumatic nasal deformity. There were four female and eleven male patients with an average age of 32 years(range 19 to 52 years). All patients had previous trauma history. Of these, closed reduction was performed on 13 patients and no treatment was 2 patients. The deformed noses were corrected through lower columellar incision, by ostectomy or osteomy, and augmentation with silicone implant. We gained satisfactory results of correcting the deformed noses, except one case with implant deviation. Our method for the correction of traumatic nasal deformity proves to be simple and safe. The camouflage effect with silicone implant overcomes an unsatisfactory correction and brings a excellent cosmetic results.

• 한국정밀공학회지
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• 제25권6호
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• pp.47-54
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• 2008

Fitting process carried out in the automobile transmission assembly line is classified into three classes; heat fitting, press fitting, and their combined fitting. Heat fitting is a method that heats gear to a suitable range under the tempering temperature and squeezes it toward the outer diameter of shaft. Its stress depends on the yield strength of gear. Press fitting is a method that generally squeezes gear toward that of shaft at room temperature by a press. Another method heats warmly gear and safely squeezes it toward that of shaft. Warm shrink fitting process for the automobile transmission part is now gradually increased, but the parts (shaft/gear) assembled by this process produced dimensional changes in both the outer diameter and profile of the gear. So that it may cause noise and vibration between gears. In order to solve these problems, we need an analysis of warm shrink fitting process, in which design parameters are involved; contact pressure according to fitting interference between outer diameter of shaft and inner diameter of gear, fitting temperature, and profile tolerance of gear. In this study, an closed form equation to predict contact pressure and fitting load was proposed in order to develop an optimization technique of the warm shrink fitting process and verified its reliability through the experimental results measured in the field and FEM, that is, thermal-structural coupled field analysis. Actual loads measured in the field was in good agreements with the results obtained by the theoretical and finite element analysis.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2012년도 학술발표회
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• pp.1-10
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• 2012

Throughout much of the world, many ecological problems have arisen in watersheds where a significant portion of stream flows are diverted to support agriculture production. Within endorheic watersheds (watersheds whose terminus is a terminal lake) these problems are magnified due to the cumulative effect that reduced stream flows have on the condition of the lake at the stream's terminus. Within an endorheic watershed, any diversion of stream flows will cause an imbalance in the terminal lake's water balance, causing the lake to transition to a new equilibrium level that has a smaller volume and surface area. However, the total mass of Total Dissolved Solids within the lake will continue to grow; resulting in a significant increase in the lake's TDS concentration over time. The ecological consequences of increased TDS concentrations can be as limited as the intermittent disruption of productive fisheries, or as drastic as a complete collapse of a lake's ecosystem. A watershed where increasing TDS concentrations have reached critical levels is the Walker Lake watershed, located on the eastern slope of the central Sierra Nevada range in Nevada, USA. The watershed has an area of 10,400 sq. km, with average annual headwater flows and stream flow diversions of 376 million $m^3/yr$ and 370 million $m^3/yr$, respectively. These diversions have resulted in the volume of Walker Lake decreasing from 11.1 billion m3 in 1882 to less than 2.0 billion $m^3$ at the present time. The resulting rise in TDS concentration has been from 2,560 mg/l in 1882 to nearly 15,000 mg/l at the current time. Changes in water management practices over the last century, as well as climate change, have contributed to this problem in varying degrees. These changes include the construction of reservoirs in the 1920s, the pumpage of shallow groundwater for irrigation in the 1960s and the implementation of high efficiency agricultural practices in the 1980s. This paper will examine the impacts that each of these actions, along with changes in the region's climate, has had on stream flow in the Walker River, and ultimately the TDS concentration in Walker Lake.

• 한국토양비료학회지
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• 제39권5호
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• pp.315-320
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• 2006

토성 측정법인 비중계법의 정도시험을 10개 표준토양을 선정하여 침강실린더내 토양현탁액의 온도를 모니터링하면서 피켓법과 비교하여 수행하였다. 토양현탁액은 $13^{\circ}C$에서 $28^{\circ}C$까지 범위로 온도가 분포하였으며 현탁액의 온도변이는 $0.2^{\circ}C$에서 $4.4^{\circ}C$ 범위였다. 비중계법에 의한 점토함량은 피켓법과 -6.4%에서 4.0%까지 차이가 발생하였다. 이 때의 양과 음의 양극단의 높은 차이는 각각 점토함량이 매우 낮은 토양과 유기물함량, 교환성칼슘, pH가 상대적으로 높은 토양이었다. 이 두 토양을 제외한 나머지 토양에서는 차이가 3%이하였으며 점토함량이 25% 이상인 토양에서는 거의 0에 가까웠다. 모래함량에서 -1.5%에서 2.0%까지 차이가 발생하였다. 차이가 가장 큰 토양은 점토함량에서와 유사하게 모래함량이 가장 낮은 토양에서 나타났다.

• 소성∙가공
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• 제17권6호
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• pp.412-419
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• 2008

Using lightweight materials in vehicle manufacturing in order to reduce energy consumption is one of the most effective approach to decrease pollutant emissions. As a lightweight material, magnesium is increasingly employed in automotive parts. However, because of its hexagonal closed-packed(HCP) crystal structure, in which only the basal plane can move, the magnesium alloy sheets show low ductility and formability at room temperature. Thus the press forming of magnesium alloy sheets has been performed at elevated temperature within range of $200^{\circ}C{\sim}250^{\circ}C$. Here we try the possibility of sheet metal forming at room temperature by adopting incremental forming technique with rotating tool, which is so called as rotational-incremental sheet forming(RISF). In this rotational-incremental sheet forming the spindle tool rotates on the surface of the sheet metal and moves incrementally with small pitch to fit the sheet metal on the desired shape. There are various variables defining the formability of sheet metals in the incremental forming such as speed of spindle, pitch size, lubricants, etc. In this study, we clarified the effects of spindle speed and pitch size upon formability of magnesium alloy sheets at room temperature. In case of 0.2, 0.3 and 0.4mm of pitch size with hemispherical rotating tool of 6.0mm radius, the maximum temperature at contact area between rotating tool and sheet metal were $119.2^{\circ}C,\;130.8^{\circ}C,\;and\;177.3^{\circ}C$. Also in case of 300, 500, and 700rpm of spindle speed, the maximum temperature at the contact area were $109.7^{\circ}C,\;130.8^{\circ}C\;and\;189.8^{\circ}C$.

• Smart Structures and Systems
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• 제25권3호
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• pp.323-335
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• 2020

Magnetorheological elastomer (MRE), a smart material, is an innovative material for base isolation system. It has magnetorheological (MR) effect that can control the stiffness in real-time. In this paper, a new hybrid base isolation system combining two electromagnetic closed circuits and the roller bearing is proposed. In the proposed system, the roller part can support the vertical load. Thus, the MRE part is free from the vertical load and can exhibit the maximum MR effect. The MRE magnetic loop is constructed in the free space of the roller bearing and forms a strong magnetic field. To demonstrate the performance of the proposed hybrid base isolation system, dynamic characteristic tests and performance evaluation were carried out. Dynamic characteristic tests were performed under the extensive range of strain of the MRE and the change of the applied current. Performance evaluation was carried out using the hybrid simulation under five earthquakes (i.e., El Centro, Kobe, Hachinohe, Northridge, and Loma Prieta). Especially, semi-active fuzzy control algorithm was applied and compared with passive type. From the performance evaluation, the comparison shows that the new hybrid base isolation system using fuzzy control algorithm is superior to passive type in reducing the acceleration and displacement responses of a target structure.

• Geosciences Journal
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• 제22권6호
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• pp.975-987
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• 2018

Stable isotope ratios of $^{18}O/^{16}O$ and $^{13}C/^{12}C$ and rare earth elements geochemistry of the Upper Triassic carbonates from the Baluti Formation in Kurdistan Region of Northern Iraq were studied in two areas, Sararu and Sarki. The aim of the study is to quantify the possible diagenetic processes that postdated deposition and the paleoenvironment of the Baluti Formation. The replacement products of the skeletal grains by selective dissolution and neomorphism probably by meteoric water preserved the original marine isotopic signatures possibly due to the closed system. The petrographic study revealed the existence of foraminifers, echinoderms, gastropods, crinoids, nodosaria and ostracods as major framework constituents. The carbonates have micritic matrix with microsparite and sparry calcite filling the pores and voids. The range and average values for twelve carbonate rocks of ${\delta}^{18}O$ and ${\delta}^{13}C$ in Sararu section were -5.3‰ to -3.16‰ (-4.12‰) and -2.94‰ to -0.96‰ (-1.75‰), respectively; while the corresponding values for the Sarki section were -3.69‰ to -0.39‰ (-2.08‰) and -5.34‰ to -2.70‰ (-4.02‰), respectively. The bivariate plot of ${\delta}^{18}O$ and ${\delta}^{13}C$ suggests that most of these carbonates are warm-water skeletons and have meteoric cement. The average ${\Sigma}REE$ content and Eu-anomaly of the carbonates of Sararu sections were 44.26 ppm and 1.03, respectively, corresponding to 22.30 ppm and 0.93 for the Sarki section. The normalized patterns for the carbonate rocks exhibit: (1) non-seawater-like REE patterns, (2) positive Gd anomalies (average = 1.112 for Sararu and 1.114 for Sarki), (3) super chondritic Y/Ho ratio is 31.48 for Sararu and 31.73 for Sarki which are less than the value of seawater. The presence of sparry calcite cement, negative $^{13}C$ and $^{18}O$ isotope values, the positive Eu anomaly in the REE patterns (particularly for Sararu), eliminated Ce anomaly ($Ce/Ce^{\ast}$: 0.916-1.167, average = 0.994 and 0.950-1.010, average = 0.964, respectively), and Er/Nd values propose that these carbonates have undergone meteoric diagenesis. The REE patterns suggest that the terrigenous materials of the Baluti were derived from felsic to intermediate rocks.