• 응용통계연구
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• 제23권6호
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• pp.1067-1080
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• 2010

임상시험을 위한 표본 수 산정방법에 대해 지금까지 많은 방법이 개발되었고 현재 국내외 임상시험 기관에서 이 방법들을 토대로 표본 수를 산정하고 있다. 하지만 마이크로어레이칩 을 이용한 실험에 필요한 표본 수 산정에 대한 연구는 아직 미비하여 제대로 이용되지 않고 있다. 본 연구의 목적은 마이크로어레이 실험에 필요한 표본 수를 산정하는 데 있어 실제 마이크로어레이 자료의 재현성에 대한 정보를 이용하여 그 지침을 제공하는데 있다. 재현성 비교에서는 5가지 검정방법 즉, Fold change, Two-sample t-test, Wilcoxon rank-sum test, SAM, LPE 방법 별로 재현성을 측정하였다. 발현 값의 표준화 방법에 있어서는 MAS5, RMA 두 가지로 세분화 하였으며 반복수에 따라 상위 20개 또는 100개 유전자에 대한 일치성도 측정하였다. 또한, 표본수를 산정하는데 있어 기존에 제시한 방법에 현실적인 정보를 이용하여 좀 더 세분화하여 실험에 필요한 표본수를 산정해 보았다.

• Korean Journal of Acupuncture
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• 제30권1호
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• pp.1-8
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• 2013

Objectives : The purpose of the present study was to examine statistical methods used in articles published on the Korean Journal of Acupuncture from 2007 through 2012. Methods : Statistical methods and statistical packages used in original articles applied with descriptive statistics or inferential statistics were organized. Results : Out of a total of 195 original articles, 18 articles used descriptive statistics only and 177 articles used inferential statistics. 142 articles used 12 types of statistical packages. SPSS was used most at 97 times(63.4%). The number of descriptive statistical methods used was a total of 417 and among them 193 were presented as tables(46.3%) and 224 were presented as graphs(53.7%). The number of inferential statistics applied was a total of 256 and analysis of variance was used most at 90 times(35.2%). The number of parametric statistical methods used was a total of 170(75.6%) and that of nonparametric statistical methods used was a total of 55(24.4%). Analysis of variance and two sample t-test were most employed in both clinical and non-clinical research. The number of multiple comparison methods applied was a total of 67 and the number of Scheffe methods among them was most at 26 times(37.7%). Conclusions : In the present study, statistical methods used in the journal over the last six years were examined. The result of this study is considered to be a basic material to be referred to when evaluating the quality of the medical journal.

• 기본간호학회지
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• 제20권4호
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• pp.438-448
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• 2013

Purpose: The purpose of this study was to investigate factors influencing clinical competence in nursing students. Method: The participants were 125 nursing students and data were collected from October 8 to December 18, 2010 using questionnaires with. Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient and stepwise multiple regression. Results: There were significant correlations for creativity, problem-solving ability, self-directed learning ability, and clinical competence. The factor influencing clinical competence the most was creativity, followed by problem-solving ability, self-directed learning ability, and grade point average score. The regression model explained 37% of variance in clinical competence. Conclusion: The results indicate that for improvement in the clinical competence of nursing students, it is necessary to develop strategies and education programs to enhance creativity, problem-solving ability, and self-directed learning ability.

• 한국간호교육학회지
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• 제20권4호
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• pp.513-522
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• 2014

Purpose: This study identifies the influences of self-directed learning ability and metacognition on clinical competence in nursing students. Method: The subjects consisted of 290 second and third year nursing students. The data were analyzed using t-tests, ANOVA, Scheffe's test, Pearson's correlation coefficients and multiple linear regression via SPSS Statistics version 18.0. Results: On a scale of 1 (lowest) to 5 (highest), the mean self-directed learning ability score of the subjects was 3.19, mean metacognition score was 3.36 and mean clinical competence score was 3.29. A positive correlation was found between clinical competence with self-directed learning ability and metacognition. The strongest predictor of clinical competence was metacognition. Conclusion: To improve the clinical competence of nursing students, these findings indicate that increasing metacognition ability is required.

• 기본간호학회지
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• 제18권3호
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• pp.365-372
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• 2011

Purpose: The purpose of this study was to examine the effects of the teaching effectiveness and clinical learning environment on the clinical practice competency in nursing students. Method: Undergraduate nursing students (268) enrolled in one of 4 universities in 2 cities completed a survey questionnaire. Collected data were analyzed using descriptive statistics, Pearson's correlation coefficient and multiple regression with the SPSS/Win 11.0 program. Results: The mean score for teaching effectiveness was 3.09 (${\pm}.53$) on a 5-point scale, for clinical learning environment, 3.09 (${\pm}.50$) on a 5-point scale, and for clinical practice competency, 3.94 (${\pm}.52$) on a 6-point scale. Significant positive correlations were found between teaching effectiveness and clinical learning environment, and clinical practice competency. The regression model explained 8.8% of clinical practice competency. Teaching effectiveness and clinical learning environment were significant predictors of clinical practice competency. Conclusion: The findings of the study suggest that teaching effectiveness and clinical learning environment be considered when developing strategies to increase clinical practice competency in nursing students.

• 응용통계연구
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• 제28권6호
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• pp.1209-1216
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• 2015

경쟁위험사건들은 다기관 임상시험과 같은 군집화된 임상연구에서 자주 관측되어진다. 본 논문에서는 하나의 군집으로 부터 얻어지는 경쟁위험 생존자료에 대해 공통 프레일티를 허락하는 결합 프레일티모형 접근법을 제안한다. 추론을 위해 어려운 적분 자체를 피하는 다단계 가능도를 사용하여, 대응하는 추론절차를 유도한다. 또한 실제자료 분석을 통해 제안된 방법을 예증한다.

• 응용통계연구
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• 제7권2호
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• pp.35-51
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• 1994

윤리적 또는 경제적 이유 때문에 임상실험(Clinical Trials)의 연구자들은 실험중간에 새로운 치료방법이나 약이 효과가 있는지 또는 해로운지를 반복해서 검정한다. 하지만 각 검정마다 정해진 유의수준을 반복해서 사용하면 전체 유의수준이 상당히 커지게 된다. 임상실험에서 발생하는 이러한 문제를 해결하기 위하여 많은 집단측정검정법 (Group Sequential Testing Procedure)들이 개발되어 왔다. 본 논문에서는 이러한 집단측정검정법들을 간략하게 비교분석하고자 한다.

• 응용통계연구
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• 제25권6호
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• pp.947-958
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• 2012

When modeling event times in biomedical studies, the outcome might be incompletely observed. In this paper, we assume that the outcome is recorded as current status failure time data. Despite well-developed literature the routine practical use of many current status data modeling methods remains infrequent due to the lack of specialized statistical software, the difficulty to assess model goodness-of-fit, as well as the possible loss of information caused by covariate grouping or discretization. We propose a model based on pseudo-observations that is convenient to implement and that allows for flexibility in the choice of the outcome. Parameter estimates are obtained based on generalized estimating equations. Examples from studies in bile duct hyperplasia and breast cancer in conjunction with simulated data illustrate the practical advantages of this model.

• 보건의료산업학회지
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• 제13권1호
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• pp.43-53
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• 2019

Objectives: This study aimed to explore and describe the factors that influence nursing professionalism in male nursing students. Methods: Participants were 172 male nursing students. Data were collected with structured questionnaires from November 1 to November 19, 2018. Data were analyzed IBM SPSS Statistics version 21 software for descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, and multiple regression. Results: Nursing professionalism in male nursing students was significantly correlated with gender stereotypes (r=-.337, p<.001) and self-leadership (r=-639, p<.001). Moreover, the significant factors of nursing professionalism in male nursing students were gender stereotypes (${\beta}=-.188$, p=.002), self-leadership (${\beta}=-.584$, p<.001), and clinical practice experience (${\beta}=-.116$, p=.046), which explained 45.3%. Conclusions: The result of this study, indicate that in order to increase nursing professionalism in male nursing students, it is necessary to develop nursing intervention programs that can improve self-leadership, reduce stereotypes, and provide positive images of clinical practice.

• 보건의료산업학회지
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• 제10권2호
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• pp.193-204
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• 2016

Objectives : The purpose of this study was to identify the mediation effect of a positive stress coping strategy between clinical practice stress and clinical practice satisfaction in nursing students. Methods : In this study, data was collected from 248 nursing students at K University in South Korea from October of 2015 to November of 2015. The collected data was analyzed using the SPSS 22.0 Statistics Program. Results : Clinical practice stress and a positive stress coping strategy were significant predictors of clinical practice satisfaction (${\beta}$=.442, p<.001). The explanatory power of the measure of clinical practice satisfaction was increased to 29.3% (p<.001) with solely clinical practice stress, and it reached 44.2% (p<.001) when a positive stress coping strategy was reflected. The results of this study confirmed that a positive stress coping strategy has a mediation effect on clinical practice stress and clinical practice satisfaction levels. Conclusions : It is necessary to develop a program to take advantage of positive stress coping skills so that nursing college students can smoothly overcome stress during their clinical training and thus improve their clinical practice experience.