• The Journal of Advanced Prosthodontics
• /
• 제13권3호
• /
• pp.172-179
• /
• 2021

Purpose. This intra-patient retrospective study of up to 10 years evaluated the clinical success and risk factors of 6- and 8-mm long implants and their respective prostheses. Materials and Methods. The sample consisted of patients treated at a Military Polyclinic dental service, who received both 6- and 8-mm long tissue level implants in the posterior region of the same arch. Data were collected from the dental charts, clinical and radiographic exams, self-report of sleep bruxism, measurement of maximum occlusal force, and clinical crown-to-implant (C/I) ratio. Data were analyzed by descriptive and inferential statistics with univariate and hierarchical multivariate models, at the 0.05 significance level. Results. The 30 patients (27 women) had 85 implants and 83 prostheses. Two implants were lost before prosthesis installation (implant survival: 97.6%). Ten events of prosthetic complication (screw tightening loss) occurred in five patients (success rate: 87.9%) in a single moment. Only the variable C/I ratio had a significant effect for repairable prosthesis complication (P<.05). Conclusion. The results suggest that 6- and 8-mm long implants have similar long-term clinical success for implants and prostheses.

• 한국산학기술학회논문지
• /
• 제22권6호
• /
• pp.420-430
• /
• 2021

입원을 경험하는 임상연구 환자가 증가하고, 이에 따라 이들을 돌보는 간호사들의 업무가 증가하고 있으나, 모호한 역할 경계로 혼란이 발생하고 있다. 본 연구는 임상연구업무 중 병동간호사의 참여가 가능한 직접실무 제공업무, 교육 및 상담업무, 옹호 및 조정업무에 대한 역할기대와 병동에서의 협력인식 및 협력 장애요인을 파악하기 위한 조사연구이다. 대상자는 병동 간호사 66명, 임상연구간호사 65명이었다. 자료수집은 SAS 9.3통계 프로그램을 이용하여 기술 통계, two-sample t-test, 𝑥² test 로 분석하였다. 연구결과, 임상연구 간호업무의 직접실무 제공영역, 교육 및 상담영역, 옹호 및 조정영역을 포함한 역할기대 점수는 병동간호사는 4.56±0.41점, 임상연구간호사는 3.83±0.60점으로 서로에 대한 역할기대 점수가 높게 나타났다. 통계적으로 병동간호사의 역할기대가 유의하게 (p<.001) 임상연구간호사보다 더 높게 나타났다. 두 군 간의 협력 인식은 5개 항목에서 유의한 차이가 나타났다. 협력장애요인으로는 업무과중과 임상연구에 대한 인식부재가 높은 순위로 나타났다. 높은 역할기대는 역할 갈등의 요소가 된다. 그러므로, 새로운 임상연구 간호업무에서의 병동간호사와 임상연구간호사의 역할 정립을 위하여 절차 마련과 효과적인 실무 관행의 정착, 공식적 시스템 운영이 필요할 것으로 사료된다. 두 군 간의 협력을 증진하기 위해서는 서로를 동반자로 생각하고 상대에 대한 전문성을 인정할 수 있는 상호 신뢰하고 협력하는 문화가 형성되어야 할 것으로 사료된다.

• 대한임상검사과학회지
• /
• 제37권3호
• /
• pp.178-184
• /
• 2005

Carry over contamination has been reduced in some systems by flushing the internal and external surfaces of the sample probe with copious amount of diluent. It between specimens should be kept as small as possible. A built-in, continuous-flow wash reservoir, which allows the simultaneous washing of the interior and exterior of the syringe needles, addresses this issue. In addition, residual contamination can further be prevented through the use of efficient needle rinsing procedures. In discrete systems with disposable reaction vessels and measuring cuvets, any carry over is entirely caused by the pipetting system. In analyzers with reuseable cuvets or flow cells, carry over may arise at every point through which high samples pass sequentially. Therefore, disposable sample probe tips can eliminate both the contamination of one sample by another inside the probe and the carry over of in specimen into the specimen in the cup. The results of the applicative carry over experiment studied on 21 items for total protein (TP), albumin (ALB), total bilirubin (TB), alkaline phosphatase (ALP), aspratate aminotranferase (AST), alanine aminotranferase (ALT), gamma glutamyl transferase (GGT), creatinine kinase (CK), lactic dehydrogenase (LD), creatnine (CRE), blood urea nitrogen (BUN), uric acid (UA), total cholesterol (TC), triglyceride (TG), glucose (GLU), amylase (AMY), calcium (CA), inorganic phosphorus (IP), sodium (Na), potassium (K), chloride (CL) tests in chematology were as follows. Evaluation of process performance less than 1% in all tests was very good, but a percentage of ALB, TP, TB, ALP, CRE, UA, TC, GLU, AMY, IP, K, Na, and CL was 0%, implying no carry over. Other tests were ALT(-0.08%), GGT(-0.09%), CK(0.08%), LD(0.06%), BUN(0.12%), TG (-0.06%), and CA(0.89%).

• 대한임상검사과학회지
• /
• 제54권1호
• /
• pp.49-60
• /
• 2022

본 연구는 COVID-19 시대에서 빠르고 정확한 진단검사를 위해 임상병리사의 역할을 파악하고, 효율적으로 대응할 수 있는 체계적인 시스템 마련을 위한 기초자료를 제공하고자 하였다. 연구 방법은 15개 의료기관을 대상으로 설문조사 및 초점 집단 면담을 통한 분석을 하였다. 검체 채취 기관(11개)을 분석한 결과, 선별검사소 운영 기관은 7개, 임상병리사 10.4명, 채취 소요시간 2.1분, 검사소요시간 5.4시간, 검사건수 9,670건, 검사인력 6.2명으로 조사되었다. 초점 집단 면담 분석결과, COVID-19검사와 관련하여 검체 채취자 및 검사자를 보호하기 위한 근무시간, 근무장소, 근무환경이 포함된 표준화된 지침은 없었다. 그리고 감염사고 발생 시 법적인 보호 조치가 미흡하며, COVID-19와 관련한 인력에 관한 규정이 마련되어 있지 않았다. 또한, 신뢰도 있는 COVID-19 검사를 위해 검체 채취자 및 분자진단 검사자의 전문적인 교육이 요구되었다. 결론적으로 COVID-19와 같은 긴급상황 감염병 발생 시 대처할 수 있는 특수검사 단기수련기관 등을 통한 전문교육의 시행과 안정적인 인력공급 할 수 있는 법적인 체계마련이 필요할 것으로 사료된다.

• 대한한의학회지
• /
• 제27권1호
• /
• pp.196-203
• /
• 2006

Objectives : The aim of this study is to investigate how does the methods of treatment and diagnosis of Traditional Korean Medicine(TKM) get the evidence of efficacy and safety and what type of efficient body and appropriate facility of the coordination center for clinical trial in TKM. Methods : We have got the information of clinical trial center or clinical collaboration center by site invitation, search of paper and reports and internet exploration for the domestic or foreign site. Results : Coordination center for clinical trial usually involves every steps of clinical trials, such as development of Case Report From (CRF), design of study, calculation of sample size, randomization, maintenance of blinding, monitoring and audit of the resource document, data and CRF, data entry, quality control of data, analysis and report. Conclusions : The body needs several aresa of experts, which are epidemiologists, biostatisticians, research nurses for coordination, data manager and programmer, and administrator. This body would be enhance and help he clinical researches including clinical trials in TKM.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제25권1호
• /
• pp.14-19
• /
• 2014

Objectives : This study was conducted in order to describe prescribing practices in treatment of pediatric bipolar disorder in a Korean inpatient sample. Methods : We performed a retrospective chart review of 66 youths who had been hospitalized and diagnosed with bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Demographics, clinical characteristics, medications used, doses, and related adverse events were examined. Results : Mood stabilizers and/or atypical antipsychotic medications were the primary treatment. Risperidone, valproate, and lithium were the most commonly used. Thirty seven patients (58.1%) were treated with combination therapy of an atypical antipsychotic and mood stabilizer for improvement of manic/mixed symptoms. Conclusion : Combination pharmacotherapy was necessary for most patients in this admission sample group. Conduct of further studies will be needed for evaluation of treatment response according to the clinical characteristics, and the safety and efficacy of treatment for child and adolescent bipolar disorder.

• 대한미생물학회지
• /
• 제21권3호
• /
• pp.393-397
• /
• 1986

Chlamydia trachomatis is one of the most common cause in non-gonococcal urethritis. There are several diagnostic methods for Chlamydia trachomatis; culture method using McCoy cell, enzyme immunoassay and direct immunofluorescence staining etc. We have studied a sensitivities of culture, chlamydiazyme and direct immunofluorescence staining(DIF). 85 male patients previously conformed to non-gonococcal urethritis have been selected in this study. Three samples were concurrently collected in the same patient. First sample was used to inoculation in McCoy cell, 2'nd sample was used to Chlamydiazyme test and 3'rd sample was used to direct immunofluorescence staining method. The results are following. 1. All culture, Chlamydiazyme and DIF positive cases are 15/85(17.7%). 2. Culture and Chlamydiazyme positive but DIF negative cases absent. 3. Culture and DIF positive, but Chlamydiazyme negative cases are 2/85(2.4%). 4. Chlamydiazyme and DIF positive, but culture negative cases are 9/85(10.6%). 5. Culture positive, but Chlamydiazyme and DIF negative cases are 6/85(7.1%). 6. Chlamydiazyme positive, but culture and DIF negative cases are 7/85(8.2%). 7. DIF positive, but culture and Chlamydiazyme negative cases are 3/85(3.5%). 8. All culture, Chlamydiazyme and DIF negative cases are 43/85(50.1%). In summarized, anyone positive cases of culture, Chlamydiazymc and DIF are 42/85(49.9%).

• 소성∙가공
• /
• 제15권9호
• /
• pp.667-672
• /
• 2006

Agglutination is one of the most commonly employed reactions in clinical diagnosis. In this paper, we have designed and fabricated nickel mold insert for injection molding of a microfluidic lab-on-a-chip for the purpose of the efficient detection of agglutination. In the presented microfluidic lab-on-a-chip, two inlets for sample blood and reagent, flow guiding microchannels, improved serpentine laminating micromixer(ISLM) and reaction microwells are fully integrated. The ISLM, recently developed by our group, can highly improve mixing of the sample blood and reagent in the microchannel, thereby enhancing reaction of agglutinogens and agglutinins. The reaction microwell was designed to contain large volume of about $25{\mu}l$ of the mixture of sample blood and reagent. The result of agglutination in the reaction microwell could be determined by means of the level of the light transmission. To achieve the cost-effectiveness, the microfluidic lab-on-a-chip was realized by the injection molding of COC(cyclic olefin copolymer) and thermal bonding of two injection molded COC substrates. To define microfeatures in the microfluidic lab-on-a-chip precisely, the nickel mold inserts of lab-on-a-chip for the injection molding were fabricated by combining the UV photolithography with a negative photoresist SU-8 and the nickel electroplating process. The microfluidic lab-on-a-chip developed in this study could be applied to various clinical diagnosis based on agglutination.

• 척추신경추나의학회지
• /
• 제1권2호
• /
• pp.11-20
• /
• 2006

Objectives: The aim of this study is to investigate clinical effects of Chuna treatment on the neck pain patient with hypolordotic cervical spine. Methods: From June 2006 to August 2006, 20 cases of neck pain patient with hypolordotic cervical spine were divided into 2 groups. Control group(n=10) was treated only acupuncture therapy, and sample group(n=10) was treated Chuna after acupuncture therapy same as control group. Degrees of pain were measured with Visual Analogue Scale(VAS), and the change of cervical curvature was assessed Depth of cervical curve, Method of Jochumsen, and Angle of cervical curve. Results: 1. After 3th and 5th treatment, there was statistical significance between control and sample group in VAS. 2. After 5th treatment, there was not statistical significance between control and sample group in Depth of cervical curve, Method of Jochumsen, and Angle of cervical curve. Conclusions: On treating the neck pain patient with hypolordotic cervical spine, Chuna treatment is more effective than only acupuncture therapy in reducing neck pain, but Chuna treatment for short-term is not more effective than only acupuncture therapy in restoring cervical curvature.

• 대한한의학회지
• /
• 제20권3호
• /
• pp.115-126
• /
• 1999

OBJECTIVES: In order to study the effect of scapular girdle taping on hemiplegic shoulder pain, a clinical study was performed. . METHODS: Forty patients with hemiplegic shoulder pain were randomized into two groups. Twenty patients underwent a standard acupuncture treatment for shoulder pain (named control group). The other twenty patients underwent the same acupuncture treatment, but scapular girdle taping was added after acpuncture treatment (named sample group). Tapes were applied to the supraspinatus, infraspinatus, deltoid and pectoris major muscles. Shoulder pain was measured with a visual analog scale. The acupuncture treatment was performed daily for 3 weeks, and the scapular girdle taping was performed for 3 weeks in the frequency of 2 times a week. RESULTS: In terms of improvement of pain, the sample group showed statistically meaningful decrease after 3 times treatment compared with control group (P<0.05). In terms of improvement of pain with shoulder subluxation, the sample group showed a statistically meaningful decrease after 3 treatments compared with the control group (P<0.05). CONCLUSIONS: These results support that scapular girdle taping is significantly effective in reducing hemiplegic shoulder pain.