Journal of the Korean Academy of Child and Adolescent Psychiatry

Korean Academy of Child and Adolescent Psychiatry (대한소아청소년정신의학회)
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Prescribing Patterns for Treatment of Pediatric Bipolar Disorder in a Korean Inpatient Sample

소아청소년 양극성장애 입원 환자의 약물 사용 특성 : 후향적 차트 분석 연구

  • Kwon, Ohyang (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Park, Subin (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Lee, Soo-Min (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Kim, Jae-Won (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Shin, Min-Sup (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Yoo, Hee-Jeong (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Cho, Soo-Churl (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital) ;
  • Kim, Bung-Nyun (Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Children's Hospital)
  • 권오향 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 박수빈 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 이수민 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 김재원 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 신민섭 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 유희정 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 조수철 (서울대학교 어린이병원 소아청소년정신건강의학과) ;
  • 김붕년 (서울대학교 어린이병원 소아청소년정신건강의학과)
  • Received : 2013.05.27
  • Accepted : 2013.12.02
  • Published : 2014.03.30
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Abstract

Objectives : This study was conducted in order to describe prescribing practices in treatment of pediatric bipolar disorder in a Korean inpatient sample. Methods : We performed a retrospective chart review of 66 youths who had been hospitalized and diagnosed with bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Demographics, clinical characteristics, medications used, doses, and related adverse events were examined. Results : Mood stabilizers and/or atypical antipsychotic medications were the primary treatment. Risperidone, valproate, and lithium were the most commonly used. Thirty seven patients (58.1%) were treated with combination therapy of an atypical antipsychotic and mood stabilizer for improvement of manic/mixed symptoms. Conclusion : Combination pharmacotherapy was necessary for most patients in this admission sample group. Conduct of further studies will be needed for evaluation of treatment response according to the clinical characteristics, and the safety and efficacy of treatment for child and adolescent bipolar disorder.

Keywords

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