• Journal of Acupuncture Research
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• v.32 no.2
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• pp.11-21
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• 2015

Objectives : To improve quality of clinical research for acupuncture and moxibustion, a guideline for clinical research protocol is needed. While developing a guideline for acupuncture and moxibustion clinical research, we reviewed the ethical and scientific aspects of protocols pointed out by the institutional review board. This will offer practical assistance to the researchers. Methods : Ethical and scientific aspects of acupuncture and moxibustion research protocols reviewed by Kyung Hee University Korean Medicine Hospital Institutional Review Board were gathered and reviewed. Results : Ethical and scientific aspects of protocol review was reported. Conclusions : The example of review will be helpful for new researchers when developing acupuncture and moxibustion clinical research protocol.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.12 no.3
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• pp.421-429
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• 2005

Purpose: This study was don(B to describe research-related activities and attitudes toward research, barriers to and support needs for undertaking research in clinical nurses. Method: Data were collected by a questionnaire from 238 clinical nurses with over one year clinical experience working at 2 university hospitals. Results: Research related activities included courses or lecture about Nursing Research 85.7%, journal reading at least once every 2 to 3 months 30.0%, memberships in academic societies 29.4%, participation in academic conferences 45.0%, conducting research 45.4%, research utilization 24.6%. The score for attitudes toward research was 3.08(range 1-5). The score of barriers to undertaking research was 3.37(1-5) and the score for support needs for undertaking research 4.14(1-5). Attitudes toward research significantly correlated with barriers to undertaking research(r=.- 36, p=.000). Barriers to undertaking research significantly correlated with support needs for conducting research(r=.23, p=.000). Nurses with experience in conducting research had more negative attitudes toward research(t=-2.130, p=0.034) and more barriers to undertaking research than those without experience in conducting research (t=2.194, p=0.029). Conclusion: These results suggest that it is necessary to increase positive attitudes toward research in clinical nurses and nursing organizations need to provide strong supports for nurses conducting research.

• Proceedings of the PSK Conference
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• 2004.10a
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• pp.90-92
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• 2004

• 대한임상약리학회:학술대회논문집
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• 1992.11a
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• pp.33-33
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• 1992

• The Journal of Korean Medicine
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• v.44 no.4
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• pp.14-25
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• 2023

Objectives: South Korea, the United States, and the United Nations have imposed extensive economic sanctions against North Korea, which increased the use of traditional Korean medicine in North Korea to maintain its national health care system. This study attempts to study the latest trends of traditional Korean medicine research through bibliographic analysis of one of the North Korean medical journals. It will then provide insights into how traditional Korean medicine is used in North Korea. Methods: This study is based on 611 clinical research articles out of 931 articles extracted from 13 volumes of Koryo Medicine (2016 ~ 2019). The articles were classified according to the researched treatment, diseases and use alongside conventional drugs. Results: Based on the analysis of Koryo Medicine, the proportion of clinical research articles investigating the treatment effects was very high (65.6%). Also, clinical research using herbal medicine as treatment was the most common, accounting for 17.69% of the total. Some of the clinical research in Koryo Medicine were conducted in tandem with conventional drug treatment, especially on acupuncture. Conclusion: This study conducted a bibliographic analysis of Koryo Medicine to understand the current status of traditional Korean medicine within North Korea. The analysis identified main diseases, treatment methods, and integration with conventional drugs in the clinical research of traditional Korean medicine. As a country actively seeking to use traditional Korean medicine, North Korea will become an interesting field of global traditional medicine and complementary medicine research.

• The Journal of KAIRB
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• v.6 no.1
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• pp.1-4
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• 2024

The strengthening of Institutional Review Board (IRB) and Human Research Protection Program (HRPP) for clinical research on advanced regenerative medicine reflecting the 3 Principles of the Belmont Report (Respect, Beneficence, Justice) is very important. The research institution IRB should naturally be in charge of managing the clinical research process. And it is crucial to reinforce HRPP for the protection of research subjects in institutions conducting advanced regeneration clinical research. So, it is needed to establish a Protection System for Advanced Regenerative Medical Research Subjects composed of clinical research management communication system for advanced regenerative medicine between KAIRB (Korean Association of IRB) of research institutes and National Management Agency for Advanced Regenerative Medical Research. In advanced regenerative medicine clinical research to verify safety and efficacy of the investigational drugs to the subjects with rare and incurable diseases rather than to treat the patients, it is hoped that a management system that guarantees the scientific characteristics of research and the rights of research subjects would be well organized and operated.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.73-83
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• 2000

Objectives: One of the most important and difficult things in SaSang Constitution Medicine is to diagnose and classify constitution. So there have been a lot of methods and tools to diagnose and classify it. We have attempted to show the reliability and clinical application of the QSCC Ⅱ (Questionnaire for the Sasang Constitution Classification Ⅱ), comparing with our own clinical research. Methods: We surveyed information from QSCC Ⅱ and compared QSCC Ⅱ' s reliability with clinical research of 54 patients' constitution(men 24, women 30). Results: Taeeum-in is the most commonly reported constitution by clinical research, and the next is Soeum-in. Soyang-in is the most commonly reported constitution by QSCC Ⅱ and the next is Taeeum-in. In Taeeum-in and Soeum-in' s items of QSCC Ⅱ, these matched those of the clinical research. Soyang-in' s items of QSCC Ⅱ did not match. Conclusions: The efficiency of QSCC Ⅱ is higher than clinical research in Taeeum-in, Soeum-in. But lower than clinical research, Soyang-in and Taeyang-in have no reliability in QSCC Ⅱ. So Soyang-in and Taeyang-in require alternative complementary studies in the future.

• Korean Journal of Clinical Laboratory Science
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• v.44 no.1
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• pp.24-30
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• 2012

In this study, we have examined the effects of the storage time and temperature on DNA quality and have also studied the effects of the hydration buffer in which DNA is dissolved. This study was performed using 160 human blood samples collected with informed consent from 2007 to 2008 in the hospital where this cohort study was performed. The DNA extracted was dissolved using distilled water (DW) or Tris-EDTA (TE) buffer, and stored in the deep freezer or refrigerator for up to 10 weeks at $-70^{\circ}C$, $-20^{\circ}C$, $4^{\circ}C$, and $25^{\circ}C$, respectively. DNA integrity was determined by the degree of smearing of DNA on the gel. After four weeks, all of the 20 DNA samples dissolved in DW and stored at $25^{\circ}C$ were entirely degraded. After 10 weeks, 6 of the 20 DNA samples dissolved in TE buffer and stored at $25^{\circ}C$ were fairly degraded, and 4 of the 20 DNA samples dissolved in DW and stored at $4^{\circ}C$ were fairly degraded. The 20 DNA samples dissolved in TE buffer and stored at $4^{\circ}C$ were stable for 10 weeks. DNA samples stored at $-20^{\circ}C$ and $-70^{\circ}C$ did not appear to degrade in either DW or TE buffer, even at the 10-week point. We suggest that TE buffer should use for DNA elution, in order to protect against degradation and to preserve DNA for a long period of time, and the samples should be stored at $-20^{\circ}C$ or $-70^{\circ}C$.

• The Korean Journal of Nuclear Medicine
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• v.32 no.6
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• pp.471-481
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• 1998

The goals of developments in nuclear medicine instrumentation are to offer a higher-quality image and to aid diagnosis, prognosis assessment or treatment planning and monitoring. It is necessary for physicists and engineers to improve or design new instrumentation and techniques, and to implement, validate, and apply these new approaches in the practice of nuclear medicine. The researches in physical properties of detectors and crystal materials and advances in image analysis technology have improved quantitative and diagnostic accuracy of nuclear medicine images. This review article presents recent developments in nuclear medicine instrumentation, including scatter and attenuation correction, new detector technology, tomographic image reconstruction methods, 511 keV imaging, dual modality imaging device, small gamma camera, PET developments, image display and analysis methods.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.514-525
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• 2011

1. Objectives This study aims to find out identify the recognition and attitude about the research ethic among Constitutional medicine researchers. 2. Methods This survey was conducted to the 37 researchers who were currently participating in Korea Constitution Multicenter Study guided by Korea institute of Oriental medicine(KIOM). The survey consist of 4 parts that level of acknowledgment about the systems and laws on clinical research ethic, clinical research experiences and education, the level of acknowledgment about Institutional Review Board(IRB) and the recognition about overall research ethic. 3. Results Thirty one questionnaires were collected. Most researchers had low level of acknowledgment about the guidelines of basic research ethic. It was proved that more than 65% of the respondents have never received education for clinical research ethic. Moreover, 70% of them felt the need for education of clinical research ethic. In addition, most of the respondents recognized the fact that IRB is responsible for ethically implementing clinical research. 39% of the researchers thought that they themselves have a firm ethical viewpoint, while the rest of the group showed somewhat difficulty on their own ethical implementation of clinical research. 4. Conclusions Most of researcher had partial awareness of regulations and laws on clinical research ethic. And Educational needs of research ethic was high. Therefore education and Public Relations need to be done to extend research ethic. Moreover, standardized course of education on research ethic should be developed and activated.