• Title/Summary/Keyword: clinical index

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Preoperative administration effect of metronidazole, ceftriaxone sodium and their combination on stenotic index of jejunal anastomotic segment of dogs

  • Rafique, Rehan;Asi, Muhammad Nadeem;Saqib, Muhammad;Hussain, Muhammad Hammad;Sial, Awais-ur-Rehman;Mushtaq, Aqsa
    • Korean Journal of Veterinary Research
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    • v.54 no.1
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    • pp.27-30
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    • 2014
  • The jejunum is the longest part of the small intestine and its lumen is mainly involved in the absorption of the nutrients. The present study was conducted to evaluate the effects of metronidazole, ceftriaxoine sodium and their combination on the stenotic index of the end to end jujunal anastomotic site. To accomplish this, 20 healthy stray dogs were subjected to end to end jejunal ansastmosis. Dogs in Group A (control) underwent jejunal anstomosis with no antibiotic prophylaxis, while those in Group B received surgery and metronidazole alone at 50 mg/kg, those in Group C received ceftriaxone sodium intravenously at 30 mg/kg body weight prior to surgery and dogs in Group D were given metronidazole in combination with ceftriaxone sodium at 50 mg/kg and 30 mg/kg, respectively, 2 h before surgical intervention. No significant difference (p > 0.05) in the stenotic index was observed at 14 days after jejunal anastomosis. These findings indicate that prophylactic administration of metronidazole and ceftriaxone sodium alone or in combination had no significant effect on the stenotic index of the jejunum.

Correlations between Body Indices and Flow-Volume Curve Parameters (신체지표와 유량-기량곡선 지표간의 상관성)

  • Jin, Bok-Hee
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.3
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    • pp.135-139
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    • 2009
  • Pulmonary function test has been know to be greatly affected by body indices, such as sex, age, height, body weight, body surface area (BSA) and body mass index (BMI), so hat this study was focused to see the relationship between body index and flow-volume curves. Subjects were 156 (male 90, female 66) and they were examined for pulmonary function test in terms of body index and correlation/multiple regression analysis of flow-volume curves at Presbyterian Medical Center from March to August, 2009. The followings results after analyzing the correlation between body index and flow-volume curves. Although flow-volume curve FEF25-75% showed close correlation with age, body weight, and body surface area, but not with body mass index. In addition, multiple regression analysis was performed to see how each body index affects flow-volume curve FEF25-75%, and FEF25-75% dispersion was explained as 74.5% with age only, 94.2% with age and height, and 96% with age, height, and sex. Therefore, sex, age and height that are mainly used for predictive formular of pulmonary function test and nomogram were important factors for pulmonary function test itself, and further study must be done for other body index.

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Distribution of Ki67 Proliferative Indices among WHO Subtypes of Non-Hodgkin's Lymphoma: Association with other Clinical Parameters

  • Hashmi, Atif Ali;Hussain, Zubaida Fida;Faridi, Naveen;Khurshid, Amna
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8759-8763
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    • 2014
  • Background: Non-hodgkin lymphoma (NHL) is a diverse group of disease encompassing divergent tumor types with contrasting clinical behaviors. We aimed to evaluate the usefulness of Ki67 index in segregating indolent from aggressive NHL and its association with clinical parameters. Materials and Methods: During a study period of 4.5 years, a total of 215 cases of lymphomas were diagnosed among of which 172 cases were NHL. Ki67 immunohistochemical staining was performed by the DAKO envision method. Average proportion of tumor cells stained was calculated to determine the proliferative index. Results: The mean age at diagnosis was 46.2 years +19.8 (3-81) with a male to female ratio of 1.5:1. Mean Ki67 index for indolent NHL included 23% for small cell, 25% for mantle cell, 28.5% for marginal zone and 34.6% for follicular lymphoma. On the other hand, mean Ki67 index for aggressive lymphomas were 66.4%, 66.9%, 80.3%, 83.3% and 94.4% for diffuse large B cell, T cell (NOS), anaplastic large cell, lymphoblastic and burkitts lymphoma respectively. No significant correlation was found between Ki67 index and other clinical parameters like age and extra nodal involvement. Conclusions: Ki67 index is a valuable IHC marker to distinguish indolent from aggressive lymphomas especially in small needle biopsies where exact typing may not be possible.

Comparison of Stress and Physiological Variables between Diabetic and Nondiabetic Adults

  • Han, Byung-Jo;Choi, Seok-Cheol;Moon, Seong-Min;Kim, Dae-Sik;Hyun, Kyung-Yae
    • Biomedical Science Letters
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    • v.18 no.4
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    • pp.384-390
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    • 2012
  • Diabetes mellitus (DM) is considered to be a serious metabolic disease which may cause systemic complications. The present study was designed to clarify a difference on stress, physiological variables and their correlation between diabetic (DM group) and nondiabetic adults (control group). The levels of body weight, waist circumference, blood pressure, body mass index, body fat mass, total cholesterol (TcH), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltransferase (GGT), total bilirubin (TB), autonomic balance (AB), stress index (SI), fatigue index (FI), and heart rate (HR) were all significantly higher in the DM group than in the control group. However, the levels of autonomic activity (AA), stress resistance (SR), and electrocardiac stability (ES) were significantly lower in the DM group than in the control group. The percentages of persons with abnormal levels in the Tch, high density lipoprotein, low density lipoprotein, TG, AST, ALT and GGT were significantly greater in the DM group than in the control group. In the correlation of glucose and hemoglobin A1c (HBA1c) to stress indices, the DM group had a significant relationship with AB, SR, SI, FI, ES, and HR, whereas the control group had no significant relationship with these, excepting AB. These results suggest that DM was harmfully associated with body, biochemical and stress indices and that blood glucose and HBA1c levels must be exhaustively regulated.

Factors Affecting Clinical Practicum Stress of Nursing Students: Using the Lazarus and Folkman's Stress-Coping Model (간호대학생의 임상실습 스트레스 영향요인에 관한 경로분석: Lazarus와 Folkman의 스트레스-대처 모델 기반으로)

  • Kim, Sung Hae;Lee, JuHee;Jang, MiRa
    • Journal of Korean Academy of Nursing
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    • v.49 no.4
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    • pp.437-448
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    • 2019
  • Purpose: This study was conducted to test a path model for the factors related to undergraduate nursing students' clinical practicum stress, based on Lazarus and Folkman's stress-coping model. Methods: This study utilized a path analysis design. A total of 235 undergraduate nursing students participated in this study. The variables in the hypothetical path model consisted of clinical practicum, emotional intelligence, self-efficacy, Nun-chi, and nursing professionalism. We tested the fit of the hypothetical path model using SPSS/WIN 23.0 and AMOS 22.0. Results: The final model fit demonstrated a satisfactory statistical acceptance level: goodness-of-fit-index=.98, adjusted goodness-of-fit-index=.91, comparative fit index=.98, normed fit index=.95, Tucker-Lewis index=.92, and root mean square error of approximation=.06. Self-efficacy (${\beta}=-.22$, p=.003) and Nun-chi behavior (${\beta}=-.17$, p=.024) were reported as significant factors affecting clinical practicum stress, explaining 10.2% of the variance. Nursing professionalism (${\beta}=.20$, p=.006) and self-efficacy (${\beta}=.45$, p<.001) had direct effects on emotional intelligence, explaining 45.9% of the variance. Self-efficacy had indirect effects on Nun-chi understanding (${\beta}=.20$, p<.001) and Nun-chi behavior (${\beta}=.09$, p=.005) through emotional intelligence. Nursing professionalism had indirect effects on Nun-chi understanding (${\beta}=.09$, p=.005) and Nun-chi behavior (${\beta}=.09$, p=.005) through emotional intelligence. The variables for self-efficacy and nursing professionalism explained 29.1% of the Nun-chi understanding and 18.2% of the Nun-chi behavior, respectively. Conclusion: In undergraduate nursing education, it is important to identify and manage factors that affect clinical practicum stress. The findings of this study emphasize the importance of Nun-chi, self-efficacy, emotional intelligence, and nursing professionalism in the development of an educational strategy for undergraduate nursing students.

Effects of Recent Life Changes on the Temporomandibular Disorders and Treatment Course (생활변화가 측두하악기능장애와 치료과정에 끼치는 영향)

  • Cheol-Ki Park;Kyung-Soo Han
    • Journal of Oral Medicine and Pain
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    • v.17 no.1
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    • pp.51-60
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    • 1992
  • 44 Temporomandibular Disorders(TMDs) patients with non-trauma and non-iatrogenic origin pressented at Wonkwang University Dental Hospital. They were grouped into experimental subjects and 85 persons without TMSDs were classified into control groups. The objectives of this study was to investigate the effects of recent life changes on the symptom severity and treatment course of TMDs. For that purpose, the author used several scales and indices, namely, Social Readjustment Rating Scale(SRRS) devised by Holmes and Rahe, SRRS-Korean revision by Hong and Jeong, Helkimos Anamnestic index, Clinical Dysfunction index, and Visual Analogue Scale treatment index(VAS Ti) transformed from VAS by the author. Data resulted from the investigation were collected by scale or index and processed with SPSS. The obtained results were as follows : 1. Life change units(LCU) and values of indices of experimental group were higher than those of control group. 2. Life change units recorded with SRRS-Korean revision were higher than those with original SRRS in all cases and significant positive correlations existed, between he two Therefore, clinical use of original SRRS in Korea is reliable and valid. 3. In experimental group, LCU were positively correlated with Helkimos Clinical Dysfunction index and VAS treatment index, but in control group LCU were not correlated with any items. From this, increase of life changes in patient with TMDs is likely to aggravate TMJ dysfunction and more likely to complicate treatment course.

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A Structural Model on the Nursing Competencies of Nursing Simulation Learners (간호시뮬레이션 학습자의 간호역량에 관한 구조모형)

  • Park, Soo Jin;Ji, Eun Sun
    • Journal of Korean Academy of Nursing
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    • v.48 no.5
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    • pp.588-600
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    • 2018
  • Purpose: The purpose of this study was to test a model of nursing competencies of nursing simulation learners. The conceptual model was based on the theory of Jeffries's simulaton theory. Methods: Data collection was conducted in October 2017 for 310 students from two nursing universities in Kyungbuk area for 20 days. Data analysis methods were covariance structure analysis using SPSS 21.0 and AMOS 22.0 statistical programs. Results: The hypothetical model was a good fit for the data. The model fit indices were comparative fit index=.97, normed fit index=.94, Tucker-Lewis Index=.97, root mean square error of approximation=.44, and standardized root mean square residual=.04. Teacher factors were directly related to simulation design characteristics, and it was confirmed that the curriculum, classroom operation and teaching method of the instructors were important factors. Learner factors were found to have a direct effect on nursing competence, self-confidence, and clinical performance that belong to nursing capacity. In particular, the results of this study indicate that the simulation design characteristics have a partial mediating effect on learner factors and clinical performance, and a complete mediating effect on learner factors and clinical judgment ability. Conclusion: In order to improve the learner's clinical performance and clinical judgment ability, it is necessary to conduct practical training through nursing simulation besides preparing the learner and the educator.

Developing CPG for Implementation of CDSS in Digital Hospitals (디지털 병원의 CDSS구현을 위한 CPG 개발)

  • Lee, Hyung-Lae;Won, Chang-Won;Lee, Sang-Chul;Park, Sang-Chan
    • Journal of Korean Society for Quality Management
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    • v.42 no.1
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    • pp.81-89
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    • 2014
  • Purpose: The purpose of this study is to propose Clinical Practice Guideline(CPG) model and Clinical Index(CI) for implementing CDSS in digital hospitals. Methods: This study uses EMR data at department of family practice in A hospital; 636 patients, 570 diseases (based on ICD 10-CM criteria), and 37,000 data related with labs and treatments. This study focuses on disease J342 which is the most high rate of incidence. Results: Using the suggested model, this study calculates frequency matrix and probability matrix to find out the correlation of diseases and labs. This study indicates the lab sets of Disease (J342) as CI for CPG. Conclusion: This study suggests CPG model including Lab-based, Disease-Based and Case-based modules. Through 6 level cased-based CPG model, especially, this study develops Clinical Index(CI) such as the Incidence Rate, Lab Rate, Disease Lab Rate, Disease confirmed by Lab.

The effect of tongue cleaner-equipped manual toothbrush on tooth and tongue cleanness and malodor index (혀 세정기가 부착된 수동칫솔이 치아와 혀의 세정도 및 구취 관리도에 미치는 영향)

  • Kim, Tae-Il;Hong, Sam-Pyo;Lee, Shin-Jae;Kang, Bong-Sun;Oh, Young-Sang;Kim, In-Kyung;Oh, Mi-Hyun
    • Journal of Periodontal and Implant Science
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    • v.38 no.4
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    • pp.699-708
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    • 2008
  • Purpose: The aim of this study was to investigate the effect of tongue cleaner-equipped manual toothbrush on tooth cleanness, tongue cleanness and malodor index. Materials and methods: 504 subjects were included in this study. At 1st visit, basic information such as age, sex, smoking amount and alcohol consumption was recorded. Self assessment by individual subjects was performed regarding satisfaction to old toothbrush and toothbrushing habit. Tooth cleanness, tongue cleanness and malodor index was assessed by professional researcher. Tongue cleaner-equipped manual toothbrush was given to each subject with proper toothbrushing instruction. After 1 month passed, self assessment and researcher assessment regarding the same index were performed and analyzed statistically by chi-square test. Results: At 1st visit subjects seem to ignore tongue cleansing and showed poor tooth cleanness index, tongue cleanness index and malodor index, however the same subjects were motivated to clean their tongue and teeth and presented statistically improved distribution pattern in tooth cleanness index, tongue cleanness index and malodor index after using tongue cleaner-equipped manual toothbrush(p<0.01). Satisfaction to tongue cleaner-equipped manual toothbrush was 98%. Conclusion: Tongue cleaner-equipped manual toothbrush would be an effective tool for maintaining good oral hygiene through improving tooth and tongue cleanness and preventing malodor formation.

Influencing factors on happiness index in clinical dental hygienists (임상치과위생사의 행복지수에 영향을 미치는 요인)

  • Min, Hee-Hong
    • Journal of Korean society of Dental Hygiene
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    • v.15 no.1
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    • pp.1-9
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    • 2015
  • Objectives: The purpose of this study is to investigate the use of happiness index in dental hygienists. This study can be used to improve the quality of life and the turnover intention in the dental hygienists. Methods: The subjects were 281 dental hygienists in Seoul, Gyeonggi-do, and Chungcheong province. A self-reported questionnaire was completed by the subjects. The questionnaire consisted of 7 questions of general characteristics of the subjects, 7 questions of dental hygiene performance, and 9 questions of happiness index. The instrument for happiness index was modified from Suh and Koo. Cronbach's alpha was 0.850 in the happiness index measure by Likert 7 scale. The instrument for professionalism was modified from Baek and consisted of 25 questions measure by Likert 5 scale. Cronbach's alpha was 0.694 in the professionalism. The instrument for turnover intention was modified from Lee and consisted of 5 questions measured by Likert 5 scale. Cronbach's alpha was 0.712 in turnover intention. Data were analyzed using SPSS 18.0. for one way ANOVA, Duncan posthoc test, Pearson correlation coefficients and hierarchical regression. Results: The means of happiness index, professionalism and turnover intention of subjects were 4.44, 3.06 and 3.05, respectively. The happiness index was higher in those who are married(4.66), those who have high income, and those who have careers in dental hygienists(4.61). There were significant differences in the happiness index by the average daily working hours, place of treatment, work intensity and off duty hours. Conclusions: This study suggests that improvement of the happiness index in clinical dental hygienists requires the continuing and systematic education program and administrative support that can reduce the turnover intention.