• Title/Summary/Keyword: city center

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An infertile patient with Y chromosome b1/b3 deletion presenting with congenital bilateral absence of the vas deferens with normal spermatogenesis

  • Kuroda, Shinnosuke;Usui, Kimitsugu;Mori, Kohei;Yasuda, Kengo;Asai, Takuo;Sanjo, Hiroyuki;Yakanaka, Hiroyuki;Takeshima, Teppei;Kawahara, Takashi;Hamanoue, Haruka;Kato, Yoshitake;Miyoshi, Yasuhide;Uemura, Hiroji;Iwasaki, Akira;Yumura, Yasushi
    • Clinical and Experimental Reproductive Medicine
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    • v.45 no.1
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    • pp.48-51
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    • 2018
  • We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was detected using Y chromosome microdeletion analysis. Testicular sperm extraction was performed after genetic counseling. The bilateral ductus deferens and a portion of the epididymis were absent, whereas the remaining epididymis was expanded. Motile intratesticular spermatozoa were successfully extracted from the seminiferous tubule. On histopathology, nearly complete spermatogenesis was confirmed in almost every seminiferous tubule. To our knowledge, this is the first case report of b1/b3 deletion with a congenital bilateral absence of the vas deferens and almost normal spermatogenesis.

Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia

  • Kuroda, Shinnosuke;Kondo, Takuya;Mori, Kohei;Yasuda, Kengo;Asai, Takuo;Sanjo, Hiroyuki;Yakanaka, Hiroyuki;Takeshima, Teppei;Kawahara, Takashi;Kato, Yoshitake;Miyoshi, Yasuhide;Uemura, Hiroji;Iwasaki, Akira;Yumura, Yasushi
    • Clinical and Experimental Reproductive Medicine
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    • v.45 no.1
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    • pp.44-47
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    • 2018
  • Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.

Pancreatic duct lavage cytology combined with a cell-block method for patients with possible pancreatic ductal adenocarcinomas, including pancreatic carcinoma in situ

  • Hiroaki Kusunose;Shinsuke Koshita;Yoshihide Kanno;Takahisa Ogawa;Toshitaka Sakai;Keisuke Yonamine;Kazuaki Miyamoto;Fumisato Kozakai;Hideyuki Anan;Kazuki Endo;Haruka Okano;Masaya Oikawa;Takashi Tsuchiya;Takashi Sawai;Yutaka Noda;Kei Ito
    • Clinical Endoscopy
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    • v.56 no.3
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    • pp.353-366
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    • 2023
  • Background/Aims: This study aimed to clarify the efficacy and safety of pancreatic duct lavage cytology combined with a cell-block method (PLC-CB) for possible pancreatic ductal adenocarcinomas (PDACs). Methods: This study included 41 patients with suspected PDACs who underwent PLC-CB mainly because they were unfit for undergoing endoscopic ultrasonography-guided fine needle aspiration. A 6-Fr double lumen catheter was mainly used to perform PLC-CB. Final diagnoses were obtained from the findings of resected specimens or clinical outcomes during surveillance after PLC-CB. Results: Histocytological evaluations using PLC-CB were performed in 87.8% (36/41) of the patients. For 31 of the 36 patients, final diagnoses (invasive PDAC, 12; pancreatic carcinoma in situ, 5; benignancy, 14) were made, and the remaining five patients were excluded due to lack of surveillance periods after PLC-CB. For 31 patients, the sensitivity, specificity, and accuracy of PLC-CB for detecting malignancy were 94.1%, 100%, and 96.8%, respectively. In addition, they were 87.5%, 100%, and 94.1%, respectively, in 17 patients without pancreatic masses detectable using endoscopic ultrasonography. Four patients developed postprocedural pancreatitis, which improved with conservative therapy. Conclusions: PLC-CB has an excellent ability to detect malignancies in patients with possible PDACs, including pancreatic carcinoma in situ.

Diagnostic value of homogenous delayed enhancement in contrast-enhanced computed tomography images and endoscopic ultrasound-guided tissue acquisition for patients with focal autoimmune pancreatitis

  • Keisuke Yonamine;Shinsuke Koshita;Yoshihide Kanno;Takahisa Ogawa;Hiroaki Kusunose;Toshitaka Sakai;Kazuaki Miyamoto;Fumisato Kozakai;Hideyuki Anan;Haruka Okano;Masaya Oikawa;Takashi Tsuchiya;Takashi Sawai;Yutaka Noda;Kei Ito
    • Clinical Endoscopy
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    • v.56 no.4
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    • pp.510-520
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    • 2023
  • Background/Aims: We aimed to investigate (1) promising clinical findings for the recognition of focal type autoimmune pancreatitis (FAIP) and (2) the impact of endoscopic ultrasound (EUS)-guided tissue acquisition (EUS-TA) on the diagnosis of FAIP. Methods: Twenty-three patients with FAIP were involved in this study, and 44 patients with resected pancreatic ductal adenocarcinoma (PDAC) were included in the control group. Results: (1) Multivariate analysis revealed that homogeneous delayed enhancement on contrast-enhanced computed tomography was a significant factor indicative of FAIP compared to PDAC (90% vs. 7%, p=0.015). (2) For 13 of 17 FAIP patients (76.5%) who underwent EUS-TA, EUS-TA aided the diagnostic confirmation of AIPs, and only one patient (5.9%) was found to have AIP after surgery. On the other hand, of the six patients who did not undergo EUS-TA, three (50.0%) underwent surgery for pancreatic lesions. Conclusions: Homogeneous delayed enhancement on contrast-enhanced computed tomography was the most useful clinical factor for discriminating FAIPs from PDACs. EUS-TA is mandatory for diagnostic confirmation of FAIP lesions and can contribute to a reduction in the rate of unnecessary surgery for patients with FAIP.

A Study on Changes and Differences in Spatial Configuration of the Urban Sub-Area Development - In the Case of Uijeongbu City (도시성장에 따른 공간구조의 변화에 관한 연구 -의정부시의 사례를 중심으로)

  • Park, Jong-Hyun;Kweon, Young;Lee, Jong-Ruyl
    • Journal of The Korean Digital Architecture Interior Association
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    • v.4 no.2
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    • pp.35-43
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    • 2004
  • Transformations of the urban spatial structure, from sub-area redevelopment to newtown development, results great influences upon existing urban condition and spatial configuration. The purpose of the study is to analyse the effect of the urban spatial configuration of Uijongbu city where experienced changes after newly development of city center and new residential area. The west part of the city where is limited in growth by military bases, ego U.S Army basecamp, were planned and established as the other axis of the city center since mid 1980's. After that new residential area which is located in far east of the city were also developed. Space syntax as a methodology has been adopted to conduct quantitative analysis which is able to interpret differences between sub-areas ; old city center, new city center, new residential area. The results of the analysis are follows ; 1) existing structure of the urban fabric, especially old city center, is sustained and intensified, 2) new city center which is west part of the city has failed to achieve organic spatial connection adjacent to old city center, 3) there is less spatial depecdency relationship between city center and new residential area where is identified as another small self-support city within the city.

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The Validity of Delimitation of City Center by Land Values and the Change in the Land Values of City Center (지가에 의한 도심 경계 설정의 타당성 및 도심의 지가 변화)

  • Park, Jieun
    • Journal of the Economic Geographical Society of Korea
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    • v.22 no.3
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    • pp.366-379
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    • 2019
  • The purpose of this study is to review how to set city center's boundaries in proportion to the highest land values and to identify the characteristics and influence of the original and the new city center. For this purpose, the land values was compared and analyzed the city of Busan as an example using officially announced land price in 2000 and 2015. The main findings of the study are as follows. First, the method of delimitation city center's boundaries as a percentage of the highest land values depends on the flow of time or the social and economic situation of each city, so a careful approach should be taken. Second, the original city center's land values have a strong influence on the surrounding areas. However, given that the PLVI was moved to the new city center and new city center's land prices has increased, it is predicted that the new city center's area in Busan will grow further in the future.

A Study on the Application of Facility Standard of Rural Public Health Center to city Public Health Center with a Focus on Area Ratio (면적구성을 중심으로 한 농어촌 보건소 표준시설 기준의 도시 보건소 적용에 관한 연구 - 대구광역시 보건소를 중심으로 -)

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    • Korean Institute of Interior Design Journal
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    • no.40
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    • pp.102-108
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    • 2003
  • Currently, there is no facility standard for a city public health center. The facility standard of rural public health center is referred to architectural plan of city public health center. This study is about architectural plan of the city public health center and have been in 7 public health centers in Daegu investigated. Conclusions can be summarized as follows: 1) The Mother and child hygienic section, area ratio which is presented by the facility standard of rural public health center must be increased in case of city public health center since function-reinforcement of the mother and child hygienic section is required. 2) Business section, the area ratio which is presented by the facility standard of rural public health center must be diminished for city public health center because it has been excessively allocated.

A study of Integrated Management Center of u-City (u-City의 도시통합운영센터 구축 연구)

  • Yoo, Jae-Duck;Park, Hong-Tae;Shin, Hyun-Sik
    • The Journal of the Korea institute of electronic communication sciences
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    • v.2 no.3
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    • pp.191-198
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    • 2007
  • It needs an Integration Management Center in u-City to mange all events for an efficiency of city function, to enhance an installed infrastructure of information, and to provide u-Service like residence, administration, and culture in real time. Integration Management Center is a place to provide a city information from gathering data of communication network, traffic network, and facilities. The u-Services in Integration Management Center need an Integrated Platform to integrate verticality and horizontality between service layer. This paper study an infrastructure of Integration Operation Center and Integrated Platform. Lastly the topics are suggested how to make it a success in u-City.

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Residual Patterns of Pesticides on Vegetables During Drying Process (건조에 따른 채소중 잔류농약의 경시변화)

  • Nam, Hwa-Jung;Kwak, Young-Ju;Kim, Chul-Gi;Han, Young-Sun;Oh, Se-Heung;Jang, Jin-Seob;Lim, Soo-Sun;Kwon, Sung-Hee;Jang, Seung-Eun;Yeo, Eun-Young;Lee, Eun-Ju;Kim, Soon-Sim;Yoon, Sin-Won
    • Journal of Food Hygiene and Safety
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    • v.22 no.4
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    • pp.300-305
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    • 2007
  • The purpose of this study is to examine changes in the residues of procymidone and diazinon in Chwinamul, pepper leaves, and young radish according to drying method. When the three vegetables were dried at room with air stream, the residues of procymidone and diazinon increased, but after being adjusted to reflect the decrease in water content of the vegetables, the residues declined by 10 to 83 percent. When they were dried in a oven, the residues of the pesticides in the vegetables also increased, but after being adjusted to reflect the drop in the water content, the residues decreased by 44 to 71 percent. According to the results, the residues of the pesticides mostly decreased after being adjusted to reflect the drop in the water content of the dried vegetables. Therefore, when judging dried agricultural products not only the decreased water content of dried vegetables but also other factors that affect pesticide residues during the drying process should be considered. This raises the need for additional research on such factors.

An Efficiency Operation Model of the u-City Operation Center (u-City 통합운영센터의 효율적인 운영모델 제안)

  • Kim, Hwa-Jong;Lee, Kyoung-Hyoun
    • 한국정보통신설비학회:학술대회논문집
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    • 2008.08a
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    • pp.59-62
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    • 2008
  • 성공적인 u-City 서비스를 제공하는데 있어 가장 중요한 역할을 수행하는 기능으로 u-City 통합운영센터가 지목되고 있다. 본 논문에서는 u-City 통합운영센터의 효율적인 운영 모델을 제안하였으며 이를 위해서 먼저 u-City 기술 참조모델을 기반으로 하는 표준화된 u-City 서비스 도입 및 운영 방안을 제시하였다. 또한 기존에 제공되고 있는 각종 도시 정보서비스를 점진적으로 u-City 서비스에서 수용하는 전략으로서 점진적 서비스 융합 방안을 제시하였다.

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