Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia

  • Kuroda, Shinnosuke (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Kondo, Takuya (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Mori, Kohei (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Yasuda, Kengo (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Asai, Takuo (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Sanjo, Hiroyuki (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Yakanaka, Hiroyuki (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Takeshima, Teppei (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Kawahara, Takashi (Department of Urology and Renal Transplantation, Yokohama City University Medical Center) ;
  • Kato, Yoshitake (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Miyoshi, Yasuhide (Department of Urology and Renal Transplantation, Yokohama City University Medical Center) ;
  • Uemura, Hiroji (Department of Urology and Renal Transplantation, Yokohama City University Medical Center) ;
  • Iwasaki, Akira (Department of Urology, Reproduction Center, Yokohama City University Medical Center) ;
  • Yumura, Yasushi (Department of Urology, Reproduction Center, Yokohama City University Medical Center)
  • Received : 2017.10.10
  • Accepted : 2018.01.23
  • Published : 2018.03.31
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Abstract

Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.

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References

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