• 대한한의학원전학회지
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• 제26권4호
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• pp.89-94
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• 2013

Objective : To collect cosmetology text in Shang Han Za Bing Lun(伤寒杂病论), to analyze theory and prescription about cosmetology before HAN(漢) dynasty, so to allow records for modern cosmetology of Traditional Chinese Medicine. Method : Through the systematize for all terms about cosmetology, to reveal the regularity about cosmetology before HAN(漢) dynasty. Result : There were damage-appearance disease in HAN(漢) dynasty, there are lots of ideas about cosmetology in Shang Han Za Bing Lun(伤寒杂病论). Conclusion : Shang Han Za Bing Lun(伤寒杂病论) is a monograph about pattern identification and treatment, and is an important ancient book for research of cosmetology of Traditional Chinese Medicine. In the further, we will research in knowledge discovery about cosmetology of Traditional Chinese Medicine. to strengthen the guidance of the theory of Zhang Zhongjing(张仲景) for clinical practice of cosmetology of Traditional Chinese Medicine.

• 대한한방소아과학회지
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• 제27권2호
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• pp.48-69
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• 2013

Objectives There are constant increase numbers of cases mumps in children. The purpose of this study is to analyze traditional Chinese medicine treatments of epidemic mumps in children through traditional Chinese medical journal research. Methods 20 studies were selected based on title keyword "Epidemic mumps" "Child" published in CAJ(China Academic Journal). Study researched about clinical effect, herbs, attachment, moxa, venesection treatments in epidemic mumps in children Results & Conclusions There are so many treatments about epidemic mumps in children through analyzing studies in CAJ. Single and combination traditional Chinese medicine treatment is more effective in epidemic mumps in children. Therefore, we need to study more about epidemic mumps in children and should make more clinical case about it.

• 대한한의정보학회지
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• 제21권2호
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• pp.11-23
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• 2015

Objectives : Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about the theory of diagnosis, the theory of herbal medicine, the theory of prescription, the theory of acupuncture and constitutional medicine to put forward a complementary perfect solution which has good clinical utility. Methods : We compared and sorted out the textbook of Korean Sasang constitutional medicine which named Sasang medicine, and also the textbook of Chinese TCM which was including Basic theory of TCM, Diagnostics of TCM, Science of Chinese materia medica, Pharmacology of traditional Chinese medical formulae, Science of acupuncture and moxibustion, Constitution of TCM, and also related papers. Results : (1) Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about diagnosis, herbal medicine, prescription and acupuncture, Sasang constitutional medicine is a medical system which gives priority to balance of organs, when Syndrome identification and treatment medicine is a medical system that gives priority to improve symptom. (2) The prescriptions of Sasang constitutional medicine are used for the treatment of basic pathogenesis in the chronic stage of the disease, which can recover vital qi, when Syndrome identification and treatment medicine are used for the treatment of stage pathogenesis in the acute stage of the disease, which can get rid of pathogenic factors. (3) There are two kind of complementary perfect solution between Sasang constitutional medicine and Syndrome identification and treatment medicine. One perfect complementary medicine is that Sasang constitutional medicine plays a major role when Syndrome identification and treatment medicine plays a supporting role. The other one is that Syndrome identification and treatment medicine plays a major role when Sasang constitutional medicine plays a supporting role. It determined by the usual symptoms and the symptoms now, vital qi and pathogenic factors, symptom and the root cause, acute stage and chronic stage, and the state of pathogenesis. Conclusion : A new perfect complementary medicine can be created which is based on the setting that Sasang constitutional medicine primarily treat the usual symptoms, vital qi, the root cause, chronic stage and basic pathogenesis when Syndrome identification and treatment medicine primarily treat the symptoms now, pathogenic factors, symptom, acute stage and stage pathogenesis.

• 대한한방소아과학회지
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• 제19권1호
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• pp.83-102
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• 2005

Objectives : This study aimed to investigate acupuncture trend of childhood nocturnal enuresis in current Traditional Chinese Medical Journals. Methods : During the period from January 2000 to August 2004, we searched all Traditional Chinese Medical Journals in oriental medical library in dongguk university. We selected 28 literatures on acupuncture treatment for nocturnal enuresis in children Results : 28 studies are included and classified by diagnosis criteria and outcome criteria. And reclassified into two large groups, case report and comparison study. Totally 2324 cases, complete cures are 1701, significant improvements 2239, complete cure rate 73.2%, total improvement rate 97.3% 33 acupuncture points are used and main meridians are bladder, conception vessel and governor vessel. Conclusion : There remains a debate about diagnosis and outcome criteria. But Acupuncture is very effective and safe in the treatment of enuretic children.

• 대한한의학원전학회지
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• 제35권4호
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• pp.115-125
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• 2022

Objectives : This study reviews whether the traditional medical thought process reflected in the Traditional Chinese Medical Treatment Plan for COVID-19 is based on existing classical texts, and examine concerns over the quality of evidence that the plan is based on. Methods : First, terminology and basic formulas composing the compound formulas in the COVID-19 TCM Treatment Plan were collected. Next, their usage in existing classical texts were searched in the medical classics database. Results : Infectious diseases similar to COVID-19 were understood as external disease due to Six Qi in the texts. Basic formulas used for treatment were those applied in Shanghan and Wenbing, among which cases where such formulas were applied in infectious diseases could be found in the classics. Conclusions : The level of evidence of the Treatment Plan suggested by various specialists could be evaluated as insufficient if we consider the literature. However, if application of such a plan could be supported institutionally, it could become a starting point for evidence generation.

• 대한한의학원전학회지
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• 제23권4호
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• pp.31-33
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• 2010

The earliest record of 'Eum-yang Interlocking(陰陽交)' is in "Hwangjenaegyeong(黃帝內經)". In this article, we reviewed the meaning of the two Chinese Characters 'On'(溫) and "Gyo"(交), discussed the meaning, mechanism and treatment principles of Eum-yang Interlocking and Three Incurable Symptoms in order to provide a theoretical basis for treating the warm febrile disease in modern times.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1745-1749
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• 2014

Background: Platycodin D (PD), a triterpenoid saponin isolated from the Chinese medicinal herb Platycodonis radix, possesses anti-cancer effects in several cancer cell lines. The aim of this study was to evaluate its anticancer activities in hepatocellular carcinoma cells. Materials and Methods: MTT and colony formation assays were performed to evaluate cell proliferation, along with flow cytometry and Western blotting for apoptosis. Cell adhesion was tested by observing cellular morphology under a microscope, while the transwell assay was employed to investigate the cell migration and invasion. Results: PD concentration-dependently inhibited cell proliferation in both HepG2 and Hep3B cells, and significantly suppressed colony formation and induced apoptosis in HepG2 cells. The protein levels of cleaved poly ADP-ribose polymerase (PARP) and Bax were up-regulated while that of survivin was down-regulated after treatment with PD. Moreover, PD not only obviously suppressed the adhesion of HepG2 cells to Matrigel, but also remarkably depressed their migration and invasion induced by 12-O-tetradecanoylphorbol 13-acetate (TPA). Conclusions: PD presents anti-cancer potential in hepatocellular carcinoma cells via inducing apoptosis, and inhibiting cell adhesion, migration and invasion, indicating promising features as a lead compound for anti-cancer agent development.

• Journal of Acupuncture Research
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• 제25권2호
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• pp.179-187
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• 2008

Objectives : The purpose of this study is to review the acupuncture treatment studies of tic disorder in traditional chinese medicine. Methods : We reviewed the 16 studies about acupuncture treatment of tic disorder which were published from 2005 through 2007. We selected those studies from CNKI(中國知識基礎設施工程 http://www.cnki.net). Results : Selected 16 studies were divided into 8 case reports and 8 control studies. CCMD(6 studies) and DSM(4 studies) were frequently used in the diagnosis of tic disorder. Acupuncture points frequently used were 百會(Baekhoe, $GV_{20}$), 太衝(Taechung, $LR_3$), 風池(Pungji, $GB_{20}$), 合谷(Hapgok, $LI_4$), 神門(Sinmun, $HT_7$), 三陰交(Sameumgyo, $SP_6$), 內關(Naegwan, $PC_6$) and so on. According to specific parts of symptom, some acupuncture points were added. Most of studies reported that acupuncture treatments of tic disorder were very effective. Conclusions : There have been reported many acupuncture treatment studies of tic disorder in traditional chinese medicine. We believe that these studies could be applied to the clinical practices in Korea.

• BMB Reports
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• 제46권8호
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• pp.422-427
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• 2013

Although BMP9 is highly capable of promoting osteogenic differentiation of mesenchymal stem cell (MSCs), the molecular mechanism involved remains to be fully elucidated. Here, we explore the possible involvement and detail role of JNKs (c-Jun N-terminal kinases) in BMP9-induced osteogenic differentiation of MSCs. It was found that BMP9 stimulated the activation of JNKs in MSCs. BMP9-induced osteogenic differentiation of MSCs was dramatically inhibited by JNKs inhibitor SP600125. Moreover, BMP9-activated Smads signaling was decreased by SP600125 treatment in MSCs. The effects of inhibitor are reproduced with adenoviruses expressing siRNA targeted JNKs. Taken together, our results revealed that JNKs was activated in BMP9-induced osteogenic differentiation of MSCs. What is most noteworthy, however, is that inhibition of JNKs activity resulted in reduction of BMP9-induced osteogenic differentiation of MSCs, implying that activation of JNKs is essential for BMP9 osteoinductive activity.

• 한국의사학회지
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• 제35권2호
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• pp.1-7
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• 2022

In this paper, medical books on measles written in the late Joseon dynasty were analyzed to examine Chosonization of recuperation and contraindications of Measles in the Late Joseon Dynasty. It was approached in terms of utilization of Chinese medicine knowledge and utilization of clinical experience in Joseon. Through this study, the following facts were newly discovered. 1) Alcohol was taboo according to Chinese doctors, but in Joseon it was considered good if used properly. 2) Beef was recommended by Chinese medical doctors, but it was taboo in Joseon. 3) Dried fish was a food specially recommended in Joseon literature. 4) Except for diet, the contents of the treatment follow the Chinese literature as it is, or there is no content. In conclusion, Korean medical doctors simply followed Chinese medicine knowledge at the beginning of the 18th century, but in the mid to late 18th century, according to the accumulation of clinical experience in Joseon, they had unique characteristics associated with medicine during the Joseon era.