• The Korea Journal of Herbology
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• v.26 no.3
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• pp.83-90
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• 2011

Objectives : This study was performed to investigate the influence of black ginseng radix extracts (BG) and ginsenoside Rg3, Rg5 on basic fibroblast growth factor (bFGF) induced proliferation, migration and capillary tubule-like formation of human umbilical vein endothelial cells (HUVECs). Methods : HUVECs were cultured with BG and ginsenoside Rg3, Rg5 at different concentrations (60, 125, 250, 500, $1,000{\mu}g/m\ell$) for 2 day In the presence of bFGF, respectively. XTT was used to detect the proliferation. Migration and tube formations were examined to detect the antiangiogenesis. Also, the chick embryo chorioallantoic membrane (CAM) assay was performed to detect the antiangiogenesis. Results : BG and ginsenoside Rg3, Rg5 significantly inhibited bFGF-induced endothelial cell proliferation and migration in a dose-dependent manner. Tube formation in bFGF-induced HUVECs were suppressed by BG and ginsenoside Rg3, Rg5. Moreover, BG and ginsenoside Rg3, Rg5 (30-$50{\mu}g$/egg) inhibited new blood vessel formation on the growing CAM. Conclusions:Based on the present results, it can be suggested that BG has a potential chemopreventive agent via antiangiogenesis.

• Nuclear Engineering and Technology
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• v.5 no.1
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• pp.3-12
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• 1973

Some physical and chemical properties of wood-plastic combinations(W.P.C.) made of domestic soft woods such as pinus densiflora, pinus rigida and poplus deltoides were measured. The rates of improvement in properties were roughly proportional to the contents of polymer or polymer mixtures in W.P.C. For the W.P.C. obtained by means radiation curing and containing 80% of polymer or polymer mixture, the hardness and water absorptirity were improved 2.2 times and 4 times those of the original wood, respectively. The improvement of hardness was especially remarkable in the W.P.C. made of pinus densiflora and polystyrene(120%) to show 7 times increased hardness. For the W.P.C. obtained by means of thermal curing and containing 80% of polymer or polymer mixture, the hardness and water absorptivity were improved 2.4 times and 3.4 times those of the non-treated woods, respectively. These data indicate that the properties of W.P.C. prepared by means of radiation curing are not much different from those of W. p. C. prepared by means of thermal curing. Both of acid resistancy and alkali resistancy of the W.P.C. were also improved remarkably in comparison with the non-treated wood.

• Archives of Pharmacal Research
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• v.18 no.5
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• pp.332-335
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• 1995

The angiogenic activity of Aloe vera (Aloe baradensis), known as a good healing plant, was investigated. We have extracted and fractionated dichloromethane extract (G1M1D1) and methanol soluble fraction of dichloromethane extract (G1M1D1M1) which contain low-molecular weight substances of Aloe vera gel. G1M1D1 and G1D1M1 fractions induced a radially arranged, spoke-sheel-like vasculature in chick embryo chorioallantoic membrane (CAM) assay. The angiogenic activity was dose-dependent and the angiogenic pattern in the CAM assay. The angiogenic activity was dose-dependent and the angiogenic pattern in the CAM assay was very similar to that of phorbol 12-myristate-13-acetate (PMA) used as a positive control. The modified CAM assay, e simple and accurate quantitating method, was used to quntitate the angiogenic activity of G1D1M1 fraction. Application of G1M1D1M1 fraction ($100\mug/egg$) resulted in much more intense angiogenesis than in control while slightly less intense angiogenesis than in PMA (100 ng/egg).

• Nuclear Engineering and Technology
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• v.4 no.4
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• pp.301-305
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• 1972

The polymerization rates of monomer or monomer mixture impregnated with catalyst into domestic soft woods such as pinus densiflora, pinus rigida and poplus deltoides e. t. c. were measured. The results were compared with those obtained by radiation curing method and the following conclusions were derived ; (1) Pinus densiflora and pinus rigida are superior to the poplus deltoides, and methyl methacrylate(M. M. A. ) is more effective than other monomers as far as the polymerization rates are only taken into account. (2) The polymerization rate of vinyl acetate is generally slow. And the polymerization rate of the monomer is the slowest in case of being impregnated into poplus deltoides. However, the polymerization rate of the comonomer composed of vinylacetate and M. M. A. is the fastest among the other monomers or monomer mixtures in woods regardless of the curing method. (3) The general trend of polymerization of monomer in wood is similar to that of monomers themselves in both curing methods if the woods contain not much resin.

• Nuclear Engineering and Technology
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• v.4 no.1
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• pp.23-30
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• 1972

A study on the preparation of wood-plastic combinations by gamma-ray induced polymerization is carried out. In monomer impregnation, the rates and amounts are determined for various woods. The polymerization rates of various monomers and monomer mixtures impregnated mainly domestic woods are studied varying the total gamma-dose and gamma-dose rates. The obtained data indicate that; 1) in impregnation of monomer, populus deltoides is the fastest in rate, and the most impregnated in amount 2) the general trends of polymerization of monomers ill woods is in the order of vinyl acetate--methyl metacrylate--styrene, ranging from 3 to 15 Mard of total does in rate of 4$\times$10$^4$rad/hr., thus vinyl acetate or methyl metacrylate is suitable monomer in view of polymerization rate, 3) the successful woods in combination with monomer are pinus rigida and pinus densiflora in view of polymerization rate, 4) the monomers in woods are more easily polymerized under the conditions of moderately lower does rate, 2.1$\times$10$^4$rad/hr.

• The Korean Journal of Zoology
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• v.29 no.4
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• pp.294-306
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• 1986

In order to find out whether myoblast cells release into the culture medium any substances that induce or promote the fusion of myoblasts, chick embryonic myoblasts were cultured and the cultured medium (muscle-conditioned medium, MCM) was collected. The MCM was then added to the newly cultured myoblasts to examine if it has fusion-promoting activity. The MCM was also analyzed for its protein content before and after its addition to the second culture. The MCM apparently showed fusion-promoting activity when applied to unfused young myoblasts, suggesting that it contained substances that promote the fusion and that had been released from cells fo the previous culture. Analysis of proteins in the myoblasts and in the MCM suggested that the released protein was absorbed by or tightly bound to myoblasts of the second culture. One of the released proteins of about 175 kilodalton was degraded to a polypeptide of approximately 145 kilodalton, which appeared to act upon the membrane proteins of unfused myoblasts so as to stimulate their membrane to fuse with neighboring cells.

• The Korean Journal of Zoology
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• v.35 no.2
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• pp.149-160
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• 1992

Using the protein A-gold complex, the mvoabrillogenesis and actin localization of cultured myoblast were invastisated. In the superstructural changes of mvogenic cell during differentiation, pectoral myoblasts contained large nucleus and numerous ribosomes but no myofibrils during the first 24 hr of cultures. Mvoblast initiated to differentiate at 3-day of culture contained the primitive myofibrillar structure. At 96 hr of culture, the mvofibrillar structure showed reletively discernable Z band but pools defined A, H and M bands. The feature of sarcomeric structure showed more defined form at cultur 5 day. In the aspect of actin localization, actin wvas diffusely detected throughout the cytoplasm of myogenic cell and nucleus during the proliferating stage. At 72 hr of culture, with the appearantc oi primitive mvofibrils, gold particles were observed in surrounding of myofibrils but still presented in overall of cytoplasm, especially in the surface and lumen of endoplasmic reticulum. With the gradual increase of culture time, local distribution of actin was readily detected within cytoplasm. In the 5-day specimen of cultures, gold particles precisely indicate the sites of actin localifation within the sarcomere. These results indicate the time of onset of myofibrill appearance and the biosynthetic and incorporation pathway of actin molecules into sarcomeric structure during myofibrillogenesis. Thus, in the present study, the first mvoabrillar structure was detected at culture 3 day, and the initiation of assembly into a typical sarcmeric structure was observed at culture 5 day. It seems, however, that the course of events on myofibrillogenesis of cultured myoblasts can be changed with great dependence of culture conditions including the number and groluth rate of mononucleated mvoblasts after seeding although the fundamental process shows identical appearances.

• Korean Journal of Human Ecology
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• v.16 no.5
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• pp.1061-1068
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• 2007

The study has sought to explore how fashion emerges as a comprehensive tool of dress for increasing its brand appeal and express one's artistic sense and fashion by using everything from make-up to hair to trappings. Therefore, when it comes to fashion trends reflected in collections, the study is designed to improve understanding of make-up as one of the elements of total fashion and to help create diverse ideas in expressing creative and free make-up that can help perfect fashion concept in harmony with all the other elements. The study has pondered upon collection, trends and fashion make-up through literature study, and has gathered image data via the Internet. It also has conducted analysis of Ethnic style reconstructed combining past and the future, East and the West, and futurism style using asymmetrical forms without no defined patterns and hi-tech textures, which emerges as a result of post-modernism. The results of the study are as follows. Ethnic fashion that pursues strange and exotic beauty is characterized by its simple and idyllic images of traditional costume in Asia or primitive clothes in Africa. Make-up represent images of matt and pale skin, tanned yellow, glossy and thickly powered squeaky white skin. Point make-up highlighted eye lines, red chick, small and voluptuous red lips. Hair and accessory seeks diversity combining various ethnic styles together such as oriental, Indian, Islam and Africa. In addition, future-oriented fashion of the 21st century, twists in texture, various kinds of materials and changes in technique help give impressions of freedom and bizarreness.

• Journal of Ginseng Research
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• v.11 no.2
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• pp.130-135
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• 1987

To detect the effect of ginseng saponin on the immune response, mice were immunized with a protein antigen (gamma-globulin of chick). Blood was then drawn from them twice, after 10 days of the first immunization and after 10 days of the second immunization respectively, and measurements were made by ELISA method of the antibody titer in antiserum. In addition, mice that has been immunized with the same antigen were treated with immunosuppressor to suppress the immune system of the mice. After the immune system was suppressed, the effect of ginseng saponin on the recovery of immune response was measured by the same method. The experimental groups those were given ginseng saponin (10 mg/kg/day) showed a little variance between-individuals, however showed much higher antibody titer than the control groups those were given the saline solution. Moreover, there was a little recovery from the immune suppression. Although the mechanism of the effect of ginseng saponin on immune response was not well loom, it is believed that ginseng saponin has the effect of increasing the synthesis of serum protein together with its action as one of the immunostimulators.

• Journal of Ginseng Research
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• v.12 no.1
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• pp.63-67
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• 1988

To investigate the effect of ginseng saponin fractions (total saponin, diol saponin and triol saponin) on the antibody production and on the recovery of immunosuppression in mouse, chick ${\gamma}$-globulin was used as immunogen and CY(cyclophosphamide) as immunosuppressive drug. The effect of ginseng saponin fractions on the production of total serum protein was investigated also. Circulating antibody was measured with ELISA method. Total saponin, dial saponin and triol saponin resulted 4 times higher titer values compared to control group in the production of antibody but resulted no effect on the recovery of immunosuppression induced by CY. From the above results ginseng saponin fractions are believed to effect on intact immune system and to promote antibody production by helping the cooperations among lymphocytes or the growth of lymphocytes. And the increase of total serum protein has no direct relations with the increase of circulatory antibody.