• Applied Chemistry for Engineering
• /
• v.20 no.3
• /
• pp.346-350
• /
• 2009

Natural state materials contain a lot of available nutrient components. Among them, natural nutrient substances are utilized not only as the ingredient of functional foods but also as the excipients of functional cosmetics and pharmaceutic. Of these nutrient substances, solubility parameters of each components were calculated to choose the most suitable solvents for solutions. The solubility parameters for each components were composed of the dispersion contribution of the molecular attractive function, the polar contribution of the molecular attractive function and the contribution of the hydrogen bonding force. The chi parameters ($\chi_{12}$) were calculated with the information of the solubility parameter for the solute and solvent and were used as the criteria for the optimal solute-solvent pair. The optimal solvents were suggested with the numerical values of chi parameters for some amino acids.

• Coupled systems mechanics
• /
• v.12 no.1
• /
• pp.83-102
• /
• 2023

First introduced in 2016, the dynamic foundation model is an interesting topic in which the foundation is described close to reality by taking into account the influence of the foundation mass in the calculation of oscillation and is an important parameter that should be considered. In this paper, a follow-up investigation is conducted with the object of the Mindlin plate on a nonlinear dynamic foundation under moving loads. The base model includes nonlinear elastic springs, linear Pasternak parameters, viscous damping, and foundation mass. The problem is formulated by the finite element analysis and solved by the Newmark-β method. The displacement results at the center of the plate are analyzed and discussed with the change of various parameters including the nonlinear stiffness, the foundation mass, and the load velocity. The dynamic response of the plate sufficiently depends on the foundation mass.

• Journal of the Korean Vacuum Society
• /
• v.12 no.1
• /
• pp.20-24
• /
• 2003

We Performed the modeling of the dielectric functions of InGaAs by using the parametric semiconductor model. Parametric model describes the analytic dielectric function as the summation of several energy-bounded Gaussian-broadened polynomials and provides a reasonably well parameterized function which can accurately reproduce the optical constants of InGaAs materials. We obtained the values of fitting parameters of an arbitrary composition $\chi$ through the parametric model. And then, from these parameters we could obtain the unknown dielectric functions of InGaAs alloy films ($0\leq\chi\leq1$).

• Advances in nano research
• /
• v.12 no.5
• /
• pp.441-455
• /
• 2022

This study explores the linear and nonlinear solutions of sigmoid functionally graded material (S-FGM) nanoplate with porous effects. A size-dependent numerical solution is established using the strain gradient theory and isogeometric finite element formulation. The nonlinear nonlocal strain gradient is developed based on the Reissner-Mindlin plate theory and the Von-Karman strain assumption. The sigmoid function is utilized to modify the classical functionally graded material to ensure the constituent volume distribution. Two different patterns of porosity distribution are investigated, viz. pattern A and pattern B, in which the porosities are symmetric and asymmetric varied across the plate's thickness, respectively. The nonlinear finite element governing equations are established for bending analysis of S-FGM nanoplates, and the Newton-Raphson iteration technique is derived from the nonlinear responses. The isogeometric finite element method is the most suitable numerical method because it can satisfy a higher-order derivative requirement of the nonlocal strain gradient theory. Several numerical results are presented to investigate the influences of porosity distributions, power indexes, aspect ratios, nonlocal and strain gradient parameters on the porous S-FGM nanoplate's linear and nonlinear bending responses.

• Korean Journal of Oriental Medicine
• /
• v.14 no.2
• /
• pp.107-112
• /
• 2008

Although the pulse diagnosis position, Guan is apart from Cun or Chi by only $10{\sim}20$ mm at most, traditional medical doctors applies different indent pressures and even they states different pulse images are felt at Cun, Guan and Chi, To support their clinical behaviors, in this study, we tested statistically whether there are differences in pulse waveform measured at these three positions with SphygmoCor system used world widely, A 30 years old female subject without any evidence of cardiovascular diseases was involved in this experiment. Radial pulse waves were recorded at three different positions on left lower arm 10 times at three positions-Cun, Guan and Chi. With ANOVA, we tested whether, among three different positions. there are any differences in 12 parameters of radial pulse waveform and in estimated AIx(Augmentation Index) as an arterial stiffness index extracted from radial pulse waveform. As results, differences in optimal indent pressure h0 were observed at different measuring positions(P<0.001) but not significantly different. And pulse pressure his were found to be different(Chi$22.60{\pm}3.06%,\;18.60{\pm}3.37%\;and\;26.4{\pm}5.02%$ respectively. Consequently. AIx at Gwan seems to be lowest and that at Chi seems to be highest. So. we assert the AIx at Chi is likely to be overestimated. In further studies. we want to examine what make differences in these parameters between measuring positions. And it also seems to be worthy to investigate the relationship between the depth of radial artery and AIx. And, ultimately, we need to determine the best measuring process including measuring position, hold-down pressure, signal quality validation and so on. so to achieve the optimal waveform which represents subject's health condition for both western medicine and traditional medicine.

• Computers and Concrete
• /
• v.27 no.5
• /
• pp.395-406
• /
• 2021

This study experimentally and analytically investigates the shear behavior of corroded reinforced concrete (RC) beams repaired using steel fiber-reinforced concrete (SFRC) in the flexural zone. The experimental parameters are the corrosion degree (0%, 12%, and 17%) and the steel fiber volume in the SFRC (1.0%, 1.5%, and 2.0%). The test results reveal that corrosion degree significantly affects the shear resistance of the beams. The shear capacity of the beam with the corrosion degree of 17% was higher than that of the uncorroded beam, whereas the shear capacity of the beam with the corrosion degree of 12% was lower than that of the uncorroded beam. The shear efficiency of damaged beams can be recovered by repairing them using SFRC that contains a reasonable amount of steel fibers. In addition, two methods to estimate the shear capacity of the repaired beams are developed using the modified truss analogy and strut-and-tie models. The estimated shear capacity of the beam using the modified truss analogy model agrees well with the experimental data.

• Yonsei Medical Journal
• /
• v.59 no.9
• /
• pp.1138-1142
• /
• 2018

This study aimed to analyze the impact of sleep deprivation (SD) on cardiac, hemodynamic, and endothelial parameters and to determine whether these are sustained with increased periods of SD. The study included 60 healthy men (mean: age $31.2{\pm}6.3years$; body mass index $24.6{\pm}2.6kg/m^2$). Hemodynamic parameters, parameters of myocardial contractility, spectral analysis of heart rate (HR) and blood pressure (BP) variability, and the sensitivity of arterial baroreflex function were evaluated. Biochemical tests were performed to assess L-arginine (L-Arg) and asymmetric dimethylarginine (ADMA) levels in reflection of endothelial nitric oxide synthase ability. Measurements of cardiovascular system parameters were obtained at 9 a.m. (baseline) on the first day of the study and 9 a.m. (24-h SD), 1 p.m. (28-h SD), and 5 p.m. (32-h SD) on the second day. Blood samples for evaluating biochemical parameters were obtained at baseline and after 24-h SD. ANOVA Friedman's test revealed a significant effect for time in relation to HR (${\chi}^2=26.04$, df=5, p=0.000), systolic BP (${\chi}^2=35.98$, df=5, p=0.000), diastolic BP (${\chi}^2=18.01$, df=5, p=0.003), and mean BP (${\chi}^2=28.32$, df=5, p=0.000). L-Arg and ADMA levels changed from $78.2{\pm}12.9$ and $0.3{\pm}0.1$ at baseline to $68.8{\pm}10.2$ and $0.4{\pm}0.1$ after 24-hr SD, respectively (p=0.001, p=0.004). SD in healthy men is associated with increases in BP, which appear to occur after 24 hours of SD and are maintained over increasing periods of SD. The observed hemodynamic changes may have resulted due to disordered vascular endothelial function, as reflected in alterations in L-Arg and ADMA levels.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.3
• /
• pp.1458-1464
• /
• 2011

This study is on the application of TOPMODEL-topographic based hydrologic model-to the runoff analysis, The test area was the ssang-chi watershed which is mountainous catchment located in the upstream of the sumjin-gang basin and the watershed area is $126.7km^2$. The six's hourly runoff and precipitation data was selected in the 2006 ~ 2009 year. And the model parameters are calibrated using observed runoff data by Pattern Search method. The topographic index of the ssang-chi catchment was produced by digital elevation model(DEM) of 100m grid. As a results of the analysis, the parameters of model, a decay facter(m), transmissivity(T0), and the unsaturated zone delay(TD) are sensible to hydrologic response, and the simulated runoff data are in good agreement with observed runoff data.

• Bulletin of the Korean Chemical Society
• /
• v.26 no.7
• /
• pp.1065-1070
• /
• 2005

$[Mn_{12}O_{12}(O_2CPh-4-SMe)_{16}(H_2O)_4]{\cdot}7CH_2Cl_2$ (1), a new single-molecule magnet complex has been successfully synthesized by substitution of acetate ligand of Mn12ac with 4-(methylthio)benzoic acid. Complex 1 crystallizes into triclinic P$\overline{1}$ with a = 18.321(3) $\AA$, b = 19.011(3) $\AA$, c = 27.230(4) $\AA$, $\alpha$ = 86.973(3)$^{\circ}$, $\beta$ = 76.919(3)$^{\circ}$, $\gamma$ = 87.613(3)$^{\circ}$, and Z = 2. In complex 1, one Mn(III) ion has an abnormal Jahn-Teller elongation axis oriented at an oxide ion. Complex 1 has two out-of-phase ac susceptibility peaks in the 2-4 K and 4-7 K regions. Effective anisotropy energy barrier and pre-exponential factor are $U_{eff}$ = 45.95 K, 1/$\tau$0 = 8.6 ${\times}\;10^9s^{-1}\;for\;{\chi}_M$'' peaks in the lower temperature region and $U_{eff}$ = 59.45 K, 1/$\tau_0$ = 2.2 ${\times}\;10^8\;s^{-1}$ for $\chi_M$'' peaks in the higher temperature region. The parameters of S = 10, g = 1.87, D = -0.40 $cm^{-1}$, and E = 0.00034 $cm^{-1}$ were obtained from the M/N${\mu}_B$ vs. H/T plot of complex 1.

• Archives of Pharmacal Research
• /
• v.17 no.2
• /
• pp.80-86
• /
• 1994

The bioavailability of digoxin generic tablets manufactures in Korea (formulations A & B) wwere compared to a standard (formulation C; Lanoxin brand digoxin, Burroughs Wellcome, USA) in 12 healthy Korean male volunteers (mean age 31.4 years) in a single dose, randomized, complete block crossover study. Using a latin square design, each of the subjects was randomized to the order number and allocated to each of the three treatments of 0.5mg oral digoxin. Digoxin conc4ntrations in serum and urine samples collected for 48 hours after dosing were measured by fluoprescence polarization immunoassy and radioimmunoassy, respectively. Treatments were compared by using nonlinear least squares regession analysis to evaluate the following pharmacokinetic parameters : maximum serum concentation $(C_{max})$; time of maximum serum concentation $(T_{max})$; area under the serum concentration-time curve $AUC_{0-12}$, $C_{max}$\;and\;(AUC_{0-12})$; and cummulative urinary excretion for 0-48 hours $(CLE_{0-48}.\;Mean\;AUC_{0-12},\;C_{max},\;and\;CUE_{0-48}$ values for formulations B and C were significantly different from formulation A (P<0.001), but not significantly diffeerent form each other. Basede on $AUL_{0-12}\;and\;CUE_{0-48}$ respectively, the relative availability of formulation B was 87.5% and 89.6% and the relative availability of formultation A was 43% and 35% when compared to formulation C(the standard).