• Korean Chemical Engineering Research
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• 제46권1호
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• pp.156-163
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• 2008

화학공장에서는 공정 이상, 장치 수명 및 경제적 환경 등에 의하여 변경이 발생하고 있다. 그리고 변경관리는 정확한 기술적 판단근거에 의한 변경 판정, 위험도 확인 및 위험성 평가 수행 등 근본적인 공정안전 기술을 바탕으로 이루어진다. 그러나 변경관리는 경험 부족, 지식 부족 및 기술인력 부족 등의 이유로 수행하기 매우 어려운 상황에 놓여있다. 본 연구에서는 화학공장 변경관리의 취약점을 파악하고 이를 적절히 보완하여 안전성을 향상할 수 있는 변경관리 체계를 구축하였다. 위험성 평가를 기반으로 하는 변경관리 절차의 정립 및 변경 여부 판단, 변경시 위험도 산정 등 변경관리 의사결정 단계들의 명확한 판단 기준 체계 정립을 통한 장치산업의 변경관리 수행 체계를 제안하였다. 이러한 안전공학 기술이 접목된 형태의 변경관리 절차를 제안하여 화학공장의 안전성 향상을 꾀하고자 하였다.

• 한국산업보건학회지
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• 제29권2호
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• pp.141-158
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• 2019

Objectives: An adverse outcome pathway is a biological pathway that disturbs homeostasis and causes toxicity. It is a conceptual framework for organizing existing biological knowledge and consists of the molecular initiating event, key event, and adverse output. The AOP concept provides intuitive risk identification that can be helpful in evaluating the carcinogenicity of chemicals and in the prevention of cancer through the assessment of chemical carcinogenicity predictions. Methods: We reviewed various papers and books related to the application of AOPs for the prevention of occupational cancer. We mainly used the internet to search for the necessary research data and information, such as via Google scholar(http://scholar.google.com), ScienceDirect(www.sciencedirect.com), Scopus(www.scopus. com), NDSL(http: //www.ndsl.kr/index.do) and PubMed(http://www.ncbi.nlm.nih.gov/pubmed). The key terms searched were "adverse outcome pathway," "toxicology," "risk assessment," "human exposure," "worker," "nanoparticle," "applications," and "occupational safety and health," among others. Results: Since it focused on the current state of AOP for the prediction of toxicity from chemical exposure at work and prospects for industrial health in the context of the AOP concept, respiratory and nanomaterial hazard assessments. AOP provides an intuitive understanding of the toxicity of chemicals as a conceptual means, and it works toward accurately predicting chemical toxicity. The AOP technique has emerged as a future-oriented alternative to the existing paradigm of chemical hazard and risk assessment. AOP can be applied to the assessment of chemical carcinogenicity along with efforts to understand the effects of chronic toxic chemicals in workplaces. Based on these predictive tools, it could be possible to bring about a breakthrough in the prevention of occupational and environmental cancer. Conclusions: The AOP tool has emerged as a future-oriented alternative to the existing paradigm of chemical hazard and risk assessment and has been widely used in the field of chemical risk assessment and the evaluation of carcinogenicity at work. It will be a useful tool for prediction, and it is possible that it can help bring about a breakthrough in the prevention of occupational and environmental cancer.

• 한국안전학회지
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• 제10권2호
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• pp.97-104
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• 1995

To evaluate readily the effect of unconfined vapor cloud explosion(UVCE) having high possibility of accident and risk in chemical industries, the expert system of UVCE was developed and its applicability on a real accident was analyzed. We found that the hazard of UVCE could be well evaluated from the TNT equivalency model and the empirical loss data produced by overpressure for chemical facilities. By using the developed expert system, the size of vapor cloud, the quantity of vaporization, the released energy, the overpressure range from explosion point, and the impact damage of each installation could be estimated respectively. Also, probable maximum loss and catastrophic loss potential for real accident( cyclohexane release in Flixborough Nypro company) were estimated and compared with damages of the accident. As a result, the developed expert system could be well applicable to real accident.

• 한국가스학회:학술대회논문집
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• 한국가스학회 1998년도 추계학술발표회 논문집
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• pp.103-108
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• 1998

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 1999년도 추계학술발표회 논문 초록집
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• pp.28-33
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• 1999

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2000년도 추계학술대회 논문집
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• pp.108-112
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• 2000

• 한국산업보건학회지
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• 제22권2호
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• pp.140-148
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• 2012

Objectives: This study was performed to provide harmonized guidelines on health and environmental classification criteria and its results of chemicals in Korea. Methods: Firstly, The history of GHS implementation in UN and Korea was reviewed. Secondly, the differences in classification criteria on health and environmental hazards among UN GHS and two Korean government agencies, Korea Ministry of Employment and Labour (KMoEL) and Korea Ministry of Environmental (KMoE). The classification results were compared between classifications of Korea Occupational Safety and Health Agency (KOSHA) based on KMoEL and classifications of Korea National Institute of Environmental Research (KNIER) based on KMoE. Finally, an inter-agency harmonization on the classification criteria and the results was suggested by comparing the classification results of 5 chemicals; Benzene, carbon disulfide, formaldehyde, toluene-2,4-diisocyanate, and trichloroethylene. Results: KMoEL and KMoE revised regulations on chemical management and published a Notices on GHS classification criteria according to UN GHS document. However, the hazard to the ozone layer contained in the latest edition of UN GHS document published in 2011 was not included yet. The differences in classifications of 5 chemicals between KOSHA and KNIER were 36.2% in health hazards and 23.4% in environmental hazards, respectively. In conclusion, we suggested that a new revision be needed to include newly contained hazard and inter-agency working party be organized to harmonize classification results.

• 한국토양비료학회지
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• 제44권1호
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• pp.38-47
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• 2011

This study focused on health risk assessment via multi-routes of As exposure to establish a target cleanup level (TCL) in abandoned mines. Soil, ground water, and rice samples were collected near ten abandoned mines in November 2009. The As contaminations measured in all samples were used for determining the probabilistic health risk by Monte-Carlo simulation techniques. The human exposure to As compound was attributed to ground water ingestion. Cancer risk probability (R) via ground water and rice intake exceeded the acceptable risk range of $10^{-6}{\sim}10^{-4}$ in all selected mines. In particular, the MB mine showed the higher R value than other mines. The non-carcinogenic effects, estimated by comparing the average As exposure with corresponding reference dose were determined by hazard quotient (HQ) values, which were less than 1.0 via ground water and rice intake in SD, NS, and MB mines. This implied that the non-carcinogenic toxic effects, due to this exposure pathway had a greater possibility to occur than those in other mines. Besides, hazard index (HI) values, representing overall toxic effects by summed the HQ values were also greater than 1.0 in SD, NS, JA, and IA mines. This revealed that non-carcinogenic toxic effects were generally occurred. The As contaminants in all selected mines exceeded the TCL values for target cancer risk ($10^{-6}$) through ground water ingestion and rice intake. However, the As level in soil was greater than TCL value for target cancer risk via inadvertent soil ingestion pathway, except for KK mine. In TCL values for target hazard quotient (THQ), the As contaminants in soil did not exceed such TCL value. On the contrary, the As levels in ground water and polished rice in SD, NS, IA, and MB mines were also beyond the TCL values via ground water and rice intake. This study concluded that the health risks through ground water and rice intake were greater than those though soil inadvertent ingestion and dermal contact. In addition, it suggests that the abandoned mines to exceed the risk-based TCL values are carefully necessary to monitor for soil remediation.

• 한국가스학회:학술대회논문집
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• 한국가스학회 2001년도 추계학술발표회 논문집
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• pp.154-157
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• 2001

• 한국가스학회지
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• 제22권2호
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• pp.1-20
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• 2018

Despite many measures, still from time to time catastrophic events occur, even after reviewing potential scenarios with HAZID tools. Therefore, it is evident that in order to prevent such events, answering the question: "What can go wrong?" requires more enhanced HAZID tools. Recently, new system based approaches have been proposed, such as STPA (system-theoretic process analysis) and Blended Hazid, but for the time being for several reasons their availability for general use is very limited. However, by making use of available advanced software and technology, traditional HAZID tools can still be improved in degree of completeness of identifying possible hazards and in work time efficiency. The new HAZID methodology proposed here, the Data-based semi-Automatic HAZard IDentification (DAHAZID), seeks to identify possible scenarios with a semi-automated system approach. Based on the two traditional HAZID tools, Hazard Operability (HAZOP) Study and Failure Modes, Effects, and Criticality Analysis (FMECA), the new method will minimize the limitations of each method. This will occur by means of a thorough systematic preparation before the tools are applied. Rather than depending on reading drawings to obtain connectivity information of process system equipment elements, this research is generating and presenting in prepopulated work sheets linked components together with all required information and space to note HAZID results. Next, this method can be integrated with proper guidelines regarding process safer design and hazard analysis. To examine its usefulness, the method will be applied to a case study.