• Journal of Power Electronics
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• v.19 no.4
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• pp.968-979
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• 2019

Recently, there has been increased interest in the study of multiphase machines due to their higher fault-tolerant capability when compared to their conventional three-phase counterparts. For six-phase machines, stator windings configured with a single isolated neutral (1N) provide significantly more post-fault torque/power than two isolated neutrals (2N). Hence, this configuration is preferred in applications where post-fault performance is critical. It is well known that min-max injection has been commonly used for three-phase and multiphase machines in healthy condition to maximize the modulation limit. However, there is a lack of discussion on min-max injection for post-fault condition. Furthermore, the effects in terms of the common-mode voltage (CMV) in modulating signals has not been discussed. This paper investigates the effect of min-max injection in post fault-tolerant control on the voltage and speed limit of a symmetrical six-phase induction machine with single isolated neutral. It is shown that the min-max injection can minimize the amplitude of reference voltage, which maximizes the modulation index and post-fault speed of the machine. This in turn results in a higher post-fault power.

• Journal of Species Research
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• v.10 no.3
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• pp.191-200
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• 2021

To study the biodiversity of bacterial species, here we report indigenous prokaryotic species of Korea. A total of 23 bacterial strains affiliated to the class Alphaproteobacteria were isolated from various environmental sources including seaweeds, seawater, fresh water, wetland/marsh, tidal sediment, plant roots, sewage and soil. Considering higher than 98.8% 16S rRNA gene sequence similarities and formation of a well-defined phylogenetic clade with named species, it was confirmed that each strain belonged to the predefined bacterial species of the class Alphaproteobacteria. There is no official report of these 23 species in Korea; 20 species of 16 genera (Mameliella, Yangia, Paracoccus, Ruegeria, Loktanella, Phaeobacter, Dinoroseobacter, Tropicimonas, Lutimaribacter, Litoreibacter, Sulfitobacter, Roseivivax, Labrenzia, Hyphomonas, Maricaulis, Thalassospira) in the order Rhodobacterales and 3 species of a single genus (Brevundimonas) in the order Caulobacterales. Gram-staining, cell morphology, basic biochemical characteristics, isolation sources, optimum temperature, growth media, and strain IDs are detailed in the species description as well as Table 1.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.79-96
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• 2023

Objectives This study was designed to review the effect of Jakyakkamchobuja-tang on rat model with rheumatoid arthritis. Methods We used seven databases (PubMed, EMBASE, Cochrane CENTRAL, China National Knowledge Infrastructure, Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, National Digital Science Library) from their inception to May 2023 without language restrictions. Systematic Review Centre for Laboratory Animal Experimentation's tool was used to evaluate the risk of bias. RevMan software (V5.4) was used for the meta-analysis. Results Five studies were selected following our inclusion criteria. The arthritis index decreased significantly (standardized mean difference=-2.06; 95% confidence interval=-3.07 to -1.04; p<0.0001) in Jakyakkamchobuja-tang group. Also, serum cytokines in serum and paw swelling degree decreased in Jakyakkamchobuja-tang group. Conclusions Jakyakkamchobuja-tang may be effective in treating rheumatoid arthritis. Although there is a limitation that the design of drug dosage varies between papers, it can be expected to be applied as an alternative to Western medicine, and it is believed to contribute to the standardization of herbal treatment for rheumatoid arthritis.

• Nuclear Engineering and Technology
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• v.56 no.4
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• pp.1385-1397
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• 2024

Bentonite is a recommended material for the multiple barriers in the final disposal of low-level radioactive waste (LLW) to prevent groundwater intrusion and nuclear species migration. However, after drying-wetting cycling during the repository construction stage and ion exchange with the concrete barrier in the long-term repository, the bentonite mechanical behaviors, including swelling capacity and hydraulic conductivity, would be further influenced by the groundwater intrusion, resulting in radioactive leakage. To comprehensively examine the factors on the mechanical characteristics of bentonite, this study presented scenarios involving MX-80 and KV-1 bentonites subjected to drying-wetting cycling and accelerated ion migration. The experiments subsequently measured free swelling, swelling pressure, and hydraulic conductivity of bentonites with intrusions of seawater, high pH, and low pH solutions. The results indicated that the solutions caused a reduction in swelling volume and pressure, and an increase in hydraulic conductivity. Specifically, the swelling capability of bentonite with drying-wetting cycling in the seawater decreased significantly by 60%, while hydraulic conductivity increased by more than three times. Therefore, the study suggested minimizing drying-wetting cycling and preventing seawater intrusion, ensuring a long service life of the multiple barriers in the LLW repository.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.991-996
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• 2015

Side population (SP) cells have stem cell-like properties with a capacity for self-renewal and are resistant to chemotherapy and radiotherapy. Therefore the presence of SP cells in human breast cancer probably has prognostic value. Objective: To investigate the characteristics of SP cells and identify the relationship between the SP cells levels and clinico-pathological parameters of the breast tumor and disease-free survival (DFS) in breast cancer patients. Materials and Methods: A total of 122 eligible breast cancer patients were consecutively recruited from January 1, 2006 to December 31, 2007 at Yunnan Tumor Hospital. All eligible subjects received conventional treatment and were followed up for seven years. Predictors of recurrence and/or metastasis and DFS were analyzed using Cox regression analysis. Human breast cancer cells were also obtained from fresh human breast cancer tissue and cultured by the nucleic acid dye Hoechst33342 with Verapami. Flow cytometry (FCM) was employed to isolate the cells of SP and non-SP types. Results: In this study, SP cells were identified using flow cytometric analysis with Hoechst 33342 dye efflux. Adjusted for age, tumor size, lymph nodal status, histological grade, the Cox model showed a higher risk of recurrence and/or metastasis positively associated with the SP cell level (1.75, 1.02-2.98), as well as with axillary lymph node metastasis (2.99, 1.76-5.09), pathology invasiveness type (1.7, 1.14-2.55), and tumor volume doubling time (TVDT) (1.54, 1.01-2.36). Conclusions: The SP cell level is independently associated with tumor progression and clinical outcome after controlling for other pathological factors. The axillary lymph node status, TVDT and the status of non-invasive or invasive tumor independently predict the prognosis of breast cancer.

• Korean Journal of Applied Biomechanics
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• v.25 no.1
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• pp.85-94
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• 2015

Purpose : The purpose of this study was to investigate the influence on the ground reaction force parameters according to wearing positions of backpack for during stair ascending and descending. Methods : Participants selected as subject were consisted of young female(n=10) and performed stairs walks(ascending and descending) with 2 types of wearing position(front of trunk[FT], rear of trunk[RT]). Passive(Fz 1) and active(Fz 2) forces of the vertical GRF were determined from time function and frequency domain. Also shear forces(Fx, Fy 1, Fy 2), dynamic postural stability index(MLSI, APSI, VSI, DPSI), loading rate and center of pressure (${\Delta}COPx$, ${\Delta}COPy$, COP area) were calculated from time function and frequency domain. Results : Fx, Fy 1, Fy 2, and Fz 1 in GRF didn't show significant differences statistically according to the wearing positions of backpack(p>.05), but stair descending showed higher forces than that of stair ascending. Particularly, Fz 2 of stair ascending showed higher forces than that of stair descending(p<.001), RT types showed higher than that of FT types(p<.05). MLSI, APSI, VSI, and DPSI of stair descending showed the increased stability index than that of stair ascending(p<.05), MLSI of RT types showed the decreased stability index than that of FT types(p<.05). Loading rate didn't show significant differences statistically according to the wearing positions of backpack(p>.05), but stair descending showed higher loading rate than that of stair ascending(p<.001). Also, ${\Delta}COPx$ in stair descending showed the increased movement than that of stair ascending(p<.05). Conclusions : A backpack of 10 kg(10 kg(ratio of body weights $17.61{\pm}1.17%$) showed significantly change GRF parameters according to wearing positions during stair ascending and descending. If possible, we suggest that the dynamic stability, in case of stairs walking with a smaller weights can be further improved.

• Journal of Microbiology and Biotechnology
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• v.33 no.7
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• pp.875-885
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• 2023

Volatile organic compounds such as benzene, toluene, ethylbenzene, and isomers of xylenes (BTEX) constitute a group of monoaromatic compounds that are found in petroleum and have been classified as priority pollutants. In this study, based on its newly sequenced genome, we reclassified the previously identified BTEX-degrading thermotolerant strain Ralstonia sp. PHS1 as Cupriavidus cauae PHS1. Also presented are the complete genome sequence of C. cauae PHS1, its annotation, species delineation, and a comparative analysis of the BTEX-degrading gene cluster. Moreover, we cloned and characterized the BTEX-degrading pathway genes in C. cauae PHS1, the BTEX-degrading gene cluster of which consists of two monooxygenases and meta-cleavage genes. A genome-wide investigation of the PHS1 coding sequence and the experimentally confirmed regioselectivity of the toluene monooxygenases and catechol 2,3-dioxygenase allowed us to reconstruct the BTEX degradation pathway. The degradation of BTEX begins with aromatic ring hydroxylation, followed by ring cleavage, and eventually enters the core carbon metabolism. The information provided here on the genome and BTEX-degrading pathway of the thermotolerant strain C. cauae PHS1 could be useful in constructing an efficient production host.

• Journal of Species Research
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• v.5 no.1
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• pp.188-200
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• 2016

During recent screening to discover indigenous prokaryotic species in South Korea, a total of 31 bacterial strains assigned to the class Gammaproteobacteria were isolated from a variety of environmental samples including soil, tidal flat, freshwater, seawater, and plant roots. From the high 16S rRNA gene sequence similarity (>98.7%) and formation of a robust phylogenetic clade with the closest species, it was determined that each strain belonged to each independent and predefined bacterial species. There is no official report that these 31 species have been described in South Korea; therefore 5 species of 3 genera in the order Alteromonadales, 11 species of 3 genera in the order Pseudomonadales, 8 species of 6 genera in the order Enterobacteriales, 2 species of 1 genera in the order Vibrionales, 1 species of 1 genera in the order Oceanospirillales, 3 species of 3 genera in the order Xanthomonadales, and 1 species in the order Spongiibacter_o within the Gammaproteobacteia are reported for proteobacterial species found in South Korea. Gram reaction, colony and cell morphology, basic biochemical characteristics, isolation source, and strain IDs are also described in the species description section.

• Korean Journal of Applied Biomechanics
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• v.25 no.3
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• pp.241-248
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• 2015

Objective : The purpose of this study was to investigate the theta on the components of ground reaction force according to the ground conditions during gait. Method : Six healthy women(mean age: 22 yrs, mean height: $166.14{\pm}2.51cm$, mean body weights: $56.61{\pm}4.58kg$) participated in this study. The medial-lateral GRF(Fx 1), anterior-posterior GRF(Fy 1, Fy 2), vertical GRF(Fz 1, Fz 2, Fz 3), and impact loading rate were determined from time function and frequency domain. Also, GRF theta were time function and forces. Results : Fx 1, Fy 1 and Fy 2 of stair descending showed significant statistically higher forces than that of level walking, and ascending. Fz 1 of stairs descending showed significant statistically higher forces than that of level walking and stairs ascending(theta $88.62^{\circ}$). Also, Fz 2 of level walking showed significant statistically higher forces than that of stairs ascending and descending(theta $65.78^{\circ}$). Fz 3 of stairs ascending showed significant statistically higher forces than that of level walking and stairs descending($65.26^{\circ}$). Impact loading rate of stairs descending showed significant statistically higher forces than that of level and ascending walking. The GRF showed similar correlation with GRF theta(r=.603) according to the ground conditions during gait. Conclusion : These results suggest that the GRF theta can be used in conjunction with a gait characteristics, prediction of loading rate and dynamic stability.

• Journal of Species Research
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• v.7 no.2
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• pp.97-103
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• 2018

In 2016, as a subset study to discover indigenous prokaryotic species in Korea, a total of 15 bacterial strains were isolated and assigned to the class Betaproteobacteria. From the high 16S rRNA gene sequence similarity (>98.8%) and formation of a robust phylogenetic clade with the closest species, it was determined that each strain belonged to each independent and predefined bacterial species. There is no official report that these 15 species have been described in Korea; therefore, 1 strain of the Aquitalea, 5 strains of the Paraburkholderia, 2 strains of the Comamonas, 1 strain of the Cupriavidus, 1 strain of the Diaphorobacter, 2 strains of the Hydrogenophaga, 1 strain of the Iodobacter, 1 strain of the Massilia and 1 strain of the Rhodoferax within the Betaproteobacteria are described for unreported bacterial species in Korea. Gram reaction, colony and cell morphology, basic biochemical characteristics, and isolation sources are also described in the species description section.