• Title/Summary/Keyword: characteristic set

Search Result 994, Processing Time 0.024 seconds

Statistical Method of Ranking Candidate Genes for the Biomarker

  • Kim, Byung-Soo;Kim, In-Young;Lee, Sun-Ho;Rha, Sun-Young
    • Communications for Statistical Applications and Methods
    • /
    • v.14 no.1
    • /
    • pp.169-182
    • /
    • 2007
  • Receive operating characteristic (ROC) approach can be employed to rank candidate genes from a microarray experiment, in particular, for the biomarker development with the purpose of population screening of a cancer. In the cancer microarray experiment based on n patients the researcher often wants to compare the tumor tissue with the normal tissue within the same individual using a common reference RNA. Ideally, this experiment produces n pairs of microarray data. However, it is often the case that there are missing values either in the normal or tumor tissue data. Practically, we have $n_1$ pairs of complete observations, $n_2$ "normal only" and $n_3$ "tumor only" data for the microarray. We refer to this data set as a mixed data set. We develop a ROC approach on the mixed data set to rank candidate genes for the biomarker development for the colorectal cancer screening. It turns out that the correlation between two ranks in terms of ROC and t statistics based on the top 50 genes of ROC rank is less than 0.6. This result indicates that employing a right approach of ranking candidate genes for the biomarker development is important for the allocation of resources.

Estimation of characteristic parameters of refrigerants by group contribution method (집단 기여법에 의한 냉매의 특성인자 예측)

  • Kim, Y.I.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
    • /
    • v.11 no.1
    • /
    • pp.125-132
    • /
    • 1999
  • Studies are being done to replace conventional refrigerants with alternatives that have low or no ozone depletion and greenhouse warming Potentials, yet possess appropriate pro perties for a refrigeration cycle. To achieve this goal, a consistent set of thermodynamic properties of the working fluid is required. A common problem with the possible alternative refrigerants is that sufficient experimental data do not exist, thus making it difficult to develp complete equations of state that can predict properties in all regions including the vapor-liquid equilibrium. One solution is the use of the generalized equation of state correlations that can predict thermodynamic properties with a minimum number of characteristic parameters. Characteristic parameters required for the generalized equation of state are, in general, critical temperature, critical pressure, critical volume and normal boiling temperature. In this study, estimation of these characteristic parameters of refrigerants by group contribution method is developed.

  • PDF

Optimum Design of an Indoor Package Air-Conditioner's Flow Path by Taguchi Method (다구찌 방법에 의한 PAC 실내기 유로의 최적설계)

  • Kim, Jang-Kweon;Oh, Seok-Hyung
    • Journal of Power System Engineering
    • /
    • v.18 no.1
    • /
    • pp.32-37
    • /
    • 2014
  • In this study, the optimum design process of an indoor package air-conditioner (PAC) was implemented by Taguchi method. The goal of this study is to obtain the best set condition of each control factor composing of an indoor PAC. The number of revolution of a double inlet sirocco fan installed in an indoor PAC was measured by the orthogonal array of $L_{18}(2^3{\times}3^4)$ and analysed by using the-smaller- the-better characteristic among the static characteristic analyses. As a result, the optimum condition of an indoor PAC was found as a set of when the cost of production, assembling and working conditions were considered. Moreover, the number of revolution of a double-inlet sirocco fan used for an optimum condition was reduced about 8.5% more than that of a standard condition for the target flowrate of $18.5m^3/min$.

Development of Hardware Simulator for PMSG Wind Power System (영구자석동기발전기 풍력시스템의 하드웨어 시뮬레이터 개발)

  • Lee, Doo-Young;Yun, Dong-Jin;Jeong, Jong-Kyou;Yang, Seung-Chul;Han, Byung-Moon;Song, Seung-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
    • /
    • v.57 no.6
    • /
    • pp.951-958
    • /
    • 2008
  • This paper describes development of hardware simulator for the PMSG wind power system, which was designed considering wind characteristic, blade characteristic and blade inertia compensation. The simulator consists of three major parts, such as wind turbine model using induction motor, PMSG generator, converter-inverter set. and control system. The turbine simulator generates torque and speed signals for a specific wind turbine with respect to given wind speed. This torque and speed signals are scaled down to fit the input of 2kW PMSG. The PMSG-side converter operates to track the maximum power point, and the grid-side inverter controls the active and reactive power supplied to the grid. The operational feasibility was verified by computer simulations with PSCAD/EMTDC, and the implementation feasibility was confirmed through experimental works with a hardware set-up.

Design of PI, PD and PID Controllers with Time Response Specifications (시간응답 설계규격을 만족하는 PI, PD, PID제어기 설계)

  • 김근식;조태신;김영철
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.9 no.4
    • /
    • pp.259-269
    • /
    • 2003
  • This paper considers the problem of determining a set of PI, PD and PID controller gains, for a given linear time invariant plant, that meets or exceeds the closed loop step response specifications. The proposed method utilizes two recent results: for a given system, (1) finding a set of stabilizing PI, PD and PID gains and (2) the relationship between time response (overshoot and speed) and the coefficients of the characteristic polynomial. The method allows us to extract a subset of PI, PD and PID gains that meets stability as well as time domain performance requirements. The intersections of two dimensional sets described by linear and quadratic inequalities in the controller design space are need to be Identified through numerical computation. The procedure is illustrated by examples.

Generalized Sensitivity Analysis at a Degenerate Optimal Solution (퇴화최적해에서 일반감도분석)

  • 박찬규;김우제;박순달
    • Journal of the Korean Operations Research and Management Science Society
    • /
    • v.25 no.4
    • /
    • pp.1-14
    • /
    • 2000
  • The methods of sensitivity analysis for linear programming can be classified in two types: sensitivity analysis using an optimal solution, and sensitivity analysis using an approximate optimal solution. As the methods of sensitivity analysis using an optimal solution, there are three sensitivity analysis methods: sensitivity analysis using an optimal basis, positive sensitivity analysis, and optimal partition sensitivity analysis. Since they may provide different characteristic regions under degeneracy, it is not easy to understand and apply the results of the three methods. In this paper, we propose a generalized sensitivity analysis that can integrate the three existing methods of sensitivity analysis. When a right-hand side or a cost coefficient is perturbed, the generalized sensitivity analysis gives different characteristic regions according to the controlling index set that denotes the set of variables allowed to have positive values in optimal solutions to the perturbed problem. We show that the three existing sensitivity analysis methods are special cases of the generalized sensitivity analysis, and present some properties of the generalized sensitivity analysis.

  • PDF

The Performance Evaluation and the Optimal Design of 2MW DFIG (2MW급 DFIG 최적 설계 및 성능 평가에 관한 연구)

  • Cho, Sung-Ho;Oh, Young-Jin;Moon, Byeong-Sun;Lee, Seung-Kuh
    • 한국신재생에너지학회:학술대회논문집
    • /
    • 2007.11a
    • /
    • pp.382-385
    • /
    • 2007
  • The optimal design and characteristic analysis of Double Fed Induction Generator(DFIG) was performed. The purpose of the paper is to verify the accuracy of design and the reliability of DFIG by experiment. A grid connection experiment is performed to confirm generating performance in wide operating range. In this experiment, 2.7MW M/G set is used. The finite element method is applied to calculate parameters and characteristic analysis of DFIG. And in order to reduce design time and efforts, Design of Experiment(DOE) is used. The experimental results are compared with the optimum design results.

  • PDF

Control Limits of Time Series Data using Hilbert-Huang Transform : Dealing with Nested Periods (힐버트-황 변환을 이용한 시계열 데이터 관리한계 : 중첩주기의 사례)

  • Suh, Jung-Yul;Lee, Sae Jae
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.37 no.4
    • /
    • pp.35-41
    • /
    • 2014
  • Real-life time series characteristic data has significant amount of non-stationary components, especially periodic components in nature. Extracting such components has required many ad-hoc techniques with external parameters set by users in a case-by-case manner. In this study, we used Empirical Mode Decomposition Method from Hilbert-Huang Transform to extract them in a systematic manner with least number of ad-hoc parameters set by users. After the periodic components are removed, the remaining time-series data can be analyzed with traditional methods such as ARIMA model. Then we suggest a different way of setting control chart limits for characteristic data with periodic components in addition to ARIMA components.

Ranked-Set Sample Wilcoxon Signed Rank Test For Quantiles Under Equal Allocation

  • Kim, Dong Hee;Kim, Hyun Gee
    • Communications for Statistical Applications and Methods
    • /
    • v.10 no.2
    • /
    • pp.535-543
    • /
    • 2003
  • A ranked set sample version of the sign test is proposed for testing hypotheses concerning the quantiles of a population characteristic by Kaur, et. al(2002). In this paper, we proposed the ranked set sample Wilcoxon signed rank test for quantiles under equal allocation. We obtain the asymptotic property and the asymptotic relative efficiencies of the proposed test statistic with respect to Wilcoxon signed rank test of simple random sample for quantiles under equal allocation. We calculate the ARE of test statistics, the proposed test statistic is more efficient than simple random sampling for all quantiles. The relative advantage of ranked set sampling is greatest at the median and tapers off in the tails.

A Novel Unweighted Combination Method for Business Failure Prediction Using Soft Set

  • Xu, Wei;Yang, Daoli
    • Journal of Information Processing Systems
    • /
    • v.15 no.6
    • /
    • pp.1489-1502
    • /
    • 2019
  • This work introduces a novel unweighted combination method (UCSS) for business failure perdition (BFP). With considering features of BFP in the age of big data, UCSS integrates the quantitative and qualitative analysis by utilizing soft set theory (SS). We adopt the conventional expert system (ES) as the basic qualitative classifier, the logistic regression model (LR) and the support vector machine (SVM) as basic quantitative classifiers. Unlike other traditional combination methods, we employ soft set theory to integrate the results of each basic classifier without weighting. In this way, UCSS inherits the advantages of ES, LR, SVM, and SS. To verify the performance of UCSS, it is applied to real datasets. We adopt ES, LR, SVM, combination models utilizing the equal weight approach (CMEW), neural network algorithm (CMNN), rough set and D-S evidence theory (CMRD), and the receiver operating characteristic curve (ROC) and SS (CFBSS) as benchmarks. The superior performance of UCSS has been verified by the empirical experiments.