• 대순사상논총
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• 제37집
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• pp.329-355
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• 2021

본 논문은 들뢰즈 체계의 형성이 칸트 체계의 '순수이성의 이상'이 역류한 결과임을 밝히고자 함을 목적으로 한다. 그의 주저인 『차이와 반복』 내에서 그의 체계를 해석하는 주요 키워드를 포착하고 이것을 통해 들뢰즈의 초월적 경험주의 체계와 칸트의 선험철학 체계 사이의 상호 변양의 양상을 살피고자 한다. 들뢰즈 체계를 해석하는 선행연구 가운데 반헤겔적인 측면에 초점이 맞추어져 있는 경향이 있는데 들뢰즈가 구축하고 있는 사유의 전개 방식을 직접적으로 추적하기 위해서는 그 출발점을 칸트로 삼아야 함이 타당하다. 근본적으로 들뢰즈는 사유의 전체 지반을 두고 볼 때 헤겔과 출발점에 있어 다르다. 물론 헤겔의 정신철학 내부에 담겨 있는 변증법적 생성의 힘을 들뢰즈도 가지고 있지만 그것이 적용되는 체계적 환경이 이미 다른 것이다. 헤겔은 의식과 세계의 선행된 기원으로부터 출발하는 원본과 복사본의 체계라면 들뢰즈는 선행된 기원으로부터 출발하지 않고 오직 복사본으로부터 출발한다. 들뢰즈 체계의 이러한 특성은 경험주의의 관념적 유희의 권리에 있다. 그의 저서에서 그가 경험주의를 언급하고 경험주의의 전통을 수용한 칸트를 언급하고 자신의 철학을 초월적 경험주의라고 명명하는 것을 보면 짐작할 수 있는 사실이다. 따라서, 칸트 선험철학 체계의 역류 결과로서의 들뢰즈 체계에 대해 알아보기 위해 그 역류 과정을 조감해보는 것이 본 논문의 주된 흐름이다. 칸트 체계를 역류하는 과정에서 칸트가 조율해 놓은 경험주의와 합리주의의 절묘한 동거와 그로부터 얻어지는 현실적 인식의 적확성은 들뢰즈에 의해 파괴되고 뒤섞이면서 경험 세계의 풍요의 환영으로 변양된다. 인식의 과학적 적확성으로부터 풍요의 환영, 들뢰즈의 입장에서 인식 체계를 조율하는 두 방식에 대해서 철학자는 선택의 권리를 가질 수 있으며 또한 정당성의 문제이기보다 의식을 통해 추구하는 가치를 기준으로 스스로가 취할 수 있는 선택의 문제인 것이다. 들뢰즈의 선택은 결국 칸트가 숨겨둔 심연의 판도라 상자를 열고 현실의 표층으로 상승시킨 결과를 낳는다.

• 대순사상논총
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• 제35집
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• pp.73-107
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• 2020

대순진리회는 교단 내부 구성원들에 있어서나 학계에 있어서나 '민족종교'로 인식되고 있다. 그런데 이 민족종교의 성격이 꽤 복잡하다. 곧 민족종교로서 민족주의를 중심으로 한민족의 선민사상을 강조하면서도, 한편으로는 인류와 세계를 구제하겠다는 세계종교의 보편성도 내포하고 있다고 주장한다. 이를 민족종교의 특수성과 세계종교의 보편성이라고 말하고 있다. 그런데 이러한 특수성과 보편성의 논리는 단지 대순진리회에만 국한된 특징이 아니다. 이미 세계적으로 많은 종교들이 민족종교와 세계종교의 두 가지 측면을 동시에 가진다고 하는 이중성을 보여 왔다. 그 가운데 본고에서 주목한 것은 근대 일본에서 형성된 교파신도다. 근대 일본 정부가 국가신도체제를 구축하는 과정에서 탄생한 교파신도는 총 13개 종파가 형성되는데, 이들의 대부분은 일본인의 민족적 전통을 계승하는 민족종교라고 하면서도, 청일전쟁과 러일전쟁을 기점으로 본격적으로 세계종교를 표방하면서 해외포교에 나선다. 그렇다면 이처럼 민족종교의 정체성을 유지하면서 세계종교를 지향했던 교파신도의 해외포교는 어떻게 귀착되었고, 이들의 세계종교화는 현재 어떻게 진행되고 있을까? 본고에서는 이처럼 민족종교와 세계종교의 이중성을 보여 왔던 교파신도의 사례를 통해 대순진리회의 세계종교의 가능성을 살펴보고, 이를 위해 대순진리회가 지향해야 하는 길에 대해 약간의 제언을 하고자 한다. 이를 위해 한국사회에서 오랫동안 논의되어 왔던 '민족종교'론 또는 '민중종교'론의 역사적 흐름에 대해 살펴볼 것이며, 한국에서 민족종교이면서 세계종교를 지향하고 있는 원불교의 사례도 점검하는 것으로 민족종교와 세계종교의 경계에 서 있는 대순진리회의 새로운 지향점에 대해 검토해 보고자 한다.

• 대순사상논총
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• 제35집
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• pp.147-180
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• 2020

이른바 '존재의 대둥지(The Great Nest of Being)'는 영원철학의 존재론으로서 영원철학의 핵심 개념이다. '존재의 대둥지'는 역사적으로 존재해 왔던 세계 종교들의 심층, 즉 존재와 의식의 홀라키(holarchy)를 단적으로 보여준다. 본고에서는 세계 주류 종교들의 심층을 파악하기 위해 다양한 존재의 대둥지를 고찰해 보고, 대순사상에 나타난 존재의 대둥지는 역사적으로 출현했던 이들 대둥지를 종합하는 성격을 지니고 있음을 밝힌다. 영원의 철학에 따르면, 궁극적 실재에 대한 여러 종교들의 차이가 실제(實際)의 차이가 아니라 단지 용어상(用語上)의 차이에 불과하다. 즉 '동일(同一)한 궁극적 실재에 대한 상이(相異)한 표현(表現)'에 불과하다는 것이다. 따라서-언어학적으로-존재의 대둥지에 나타난 궁극적 실재관은 '동일한 기의(記意, signifié)', '상이한 기표(記標, signifiant)'로 요약된다. 그런데 선행연구에서 밝힌 바와 같이 대순사상에서의 궁극적 실재는 초월적·인격적 존재인 동시에 내재적·비인격적이다. 이러한 사실은 특히 대순의 종지(宗旨)에 구체적으로 명시되어 있다. 즉 대순의 종지는 기존 종교사상의 존재의 대둥지에서 나타나는 실재에 대한 개념들과 그 지향점을 함축적으로 내포하고 있을 뿐만 아니라, 기존 종교사상들이 내세웠던 이념들을 두루 아우를 수 있는-온 우주(The Kosmos)의 네 코너로서 사상한(four quardrants, AQAL)으로 고찰해 보면-범(凡) 우주적 이념을 두루 포괄한다. 따라서 대순사상의 종지(宗旨)는 궁극적 실재에 관한 세계 주요 종교사상의 동일한 기의(記意)를 아우르고, 상이한 기표(記標)를 해소할 수 있는 단초(端初)를 제공한다.

• 대순사상논총
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• 제33집
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• pp.219-255
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• 2019

'도(道)'는 동아시아 종교 사상의 관점에서 '궁극적 실재'를 나타내는 주요한 용어이다. 대순사상이 지향점으로 삼고 있는 도통진경에 이르기 위해서는 도(道)에 대한 개념의 이해가 필수적으로 선행되어야 할 것이다. 『전경(典經)』에는 금문(金文)에 처음 등장하는 '길'로서의 도에서부터 음양(陰陽)의 도, 인도(人道), 천도(天道) 등 각기 다양한 도의 개념이 나타나고 있다. 이를 상도(常道), 천도(天道), 신도(神道), 인도(人道), 상생(相生)의 도 다섯 가지 '도'로 분류하였다. 우주만물의 생성과 성장, 소멸하는 모든 자연현상은 천지자연의 이치이다. 따라서 대순사상에서의 상도는 자연계와 신계뿐만 아니라 인간계에도 적용되는 영원불변의 진리이자 천지의 운행 법칙으로 인간의 행위에도 궁극적인 준칙이 된다. 천도(天道)는 천을 주재하고 통제 관장한다는 관점에서 구천상제의 '대순진리'이자 세상을 구제하는 '제세대도'라고 본다. 신도는 모사재천 성사재인에 의해 '신의 법칙과 뜻에 따라 인간이 일을 완성해야 하는 도' 즉 '상제의 천명에 의해 신과 인간이 인의예지를 지향점으로 함께 신인합일을 이루는 도'라고 할 수 있다. 세상이 우환과 위기에 빠졌을 때 요청되는 성인의 도를 『전경』에서는 요순의 도로 상징하고 있다. 진멸해 가는 세상에서 천하를 구하고 창생을 구제하는 대순사상의 성인의 도는 '제생 의세(濟生醫世)'라 한다. 제생의세는 구천상제의 천명인 제세대도를 따르는 인간의 도리라 할 수 있으며 대순사상의 인도(人道)의 특징이라고 볼 수 있다. 상생의 도는 '상도를 다시 세우고 제생의세의 인도를 펼치는 도'이며 남을 잘되게 해야 내가 사는 후천의 윤리로 상극적 세상을 바로 잡는 진법이라고 할 수 있다. 이를 종합하면 천계와 지계, 신계와 인간계 모든 곳에 치우침 없이 적용되고 작동되는 구천상제의 제세대도로서 대순진리라고 할 수 있다. 대순사상의 도는 그것이 등장한 시대적 배경과 사상적 특징을 담고 있다. 중국 고전에서 말하는 도와 동아시아의 사상을 대표하는 유·불·도에서 전개하는 도의 전통적 개념을 수용하면서도 특별히 신앙대상으로서의 상제의 의지를 내포하고 있다는 점에서 특수성을 보인다. 대순사상은 도 개념을 규정하는 과정에서 한국 근대의 민족종교사상이 지닌 보편성과 특수성의 양 갈래를 조화하고 발전시키면서 전개되어 나왔다는 것을 알 수 있다.

• 대순사상논총
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• 제33집
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• pp.91-145
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• 2019

본 논문은 구천상제를 신앙의 대상으로 여기고 음양합덕·신인조화·해원상생·도통진경을 종지로 하여 상생의 등불, 수도의 터전, 인존시대를 여는 대순진리회 여주본부도장을 풍수학의 형기(形氣)적 이치를 통해 개벽공사 성지(聖地)임을 밝히고자 하였다. 그러기 위해서는 이를 입증할 수 있는 대순진리회 여주본부도장의 지리적 위치, 산수의 음양관계, 지맥(地脈)의 행도(行度) 과정 등 풍수지리 전반에 걸쳐 고찰이 필요하다 하겠다. 동시에 인간개조와 정신개벽으로 포덕천하(布德天下), 구제창생(救濟蒼生), 지상천국(地上天國) 건설을 목적으로 포덕(布德)·교화(敎化)·수도(修道)의 기본사업과 구호자선사업·사회복지사업·교육사업의 3대 중요사업을 추진해오고 있는 대순진리회 여주본부도장이 후천개벽의 인존시대를 열어갈 풍수적 적지임을 말해주는 용(龍), 혈(穴), 사(砂), 수(水)의 상호작용에 관한 연구도 매우 중요하다. 종단의 중심인 여주본부도장은 배산임수(背山臨水)의 풍수적 국세를 두루 갖추고 있다. 인류 해원상생(解冤相生)의 중심인 대순진리회 여주본부도장에 대한 풍수적 고찰을 통하여 풍수적 상징성과 보은상생(報恩相生)의 윤리 실천을 통해 미래를 밝혀 나갈 생왕지지(生旺之地)에 대해 탐색하고, 팔방(八方)의 상서로운 기운이 모인 이곳 본부도장의 영험한 명당국세의 수도처적(修道處的) 지세와 형국, 맑은 수기(水氣)와 어울린 지맥(地脈), 산수유정한 국세, 용혈사수(龍穴砂水)의 이치에 부합한 여주본부도장의 풍수적 입지를 밝히고자 했다. 따라서 본 논문의 주제인 대순진리회 여주본부도장의 풍수적 입지와 관련하여 현장을 중심으로 산과 물의 흐름을 풍수지리 이치에 근거하여 살피고 주변의 산세가 어떤 형태로 호응하고 있는지를 전반적으로 살펴보았다. 여주본부도장을 중심으로 사신사(四神砂)인 청룡, 백호, 주작, 현무 등의 포국(布局)과 입지의 연관성을 고찰하고자 형기론(形氣論)을 중심으로 전래 된 전통 지리서(地理書) 등을 토대로 여주본부도장의 풍수적 연구의 타당성을 뒷받침하고자 했다.

• 대순사상논총
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• 제23권
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• pp.241-292
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• 2014

This article as an attempt to analyze Jin-beop-joo(眞法呪, incantation of true law) and the view of Yang-wui Sangje(兩位上帝, Sangje in two Godship) corresponds to the second preliminary work prior to the research on the view of Sangje in Daesoonjinrihoe. The points of this article are as follows: First, Jin-beop-joo and 15 Godship(神位) based hereupon are one of the most essential elements comprising the view of Sangje in Daesoonjinrihoe. Since the other Jeungsan line religious orders except Daesoonjinrihoe does not use 15 Godship in explaining and understanding Jeungsan, this fact should be regarded as an important characteristic of Daesoonjinrihoe. Second, 15 Godship is the important installation to assemble Sangje and the other gods in the same place. In Buddhism temples and China-Taoism temples, the gods each are placed in a separate palace. Whereas Sangje and the gods are concentrated in the same place, Yound-Dae(靈臺) which is the shrine of Daesoonjinrihoe. This fact shows Sangje takes the reins to the gods visually. 15 Godship facilitates that system. Third, the number 15 of 15 Godship symbolizes the natural laws of the cosmos. Thus the shrine of Daesoonjinrihoe implies the law of universe emblematically. Forth, 15 Godship shows that the Highest God in Daesoonjinrihoe are located in the middle of the functional gods ruling over nature like mountain, sea, season, the Great Dipper, and Taoistic or Buddhistic gods like Ok-hwang Sangje(玉皇上帝, The Great Jade Emperor), Seoga-Yeorae(釋迦如來, Tathāgata Buddha), Kwan-seong-Jegoon(關聖帝君, Holy god Guan Yu), along with various envoys and ancestral gods. Besides, considering the fact that the majority of 15 Godship consists of the Eastern deities, it verifies the view of Sangje in Daesoonjinrihoe is built in the Eastern religions. Fifth, whereas the other Jeungsan line religious orders have a tendency of understanding Jeungsan as Ok-hwang Sangje, Daesoonjinrihoe worships Jeungsan as Gu-cheon Sangje(九天上帝), not as Ok-hwang Sangje. This accords with the following fact; Jeungsan is the highest ruling entity in Gu-cheon, whereas in Jinbeonju, which was handed down from Jeungsan, the highest ruling entitiy in Gu-cheon is expressed as a different being from Ok-hwang Sangje. Sixth, Daesoonjinrihoe understands Sangje as the form of two Godship, Yang-wui Sangje, which are Gu-cheon Sangje and Ok-hwang Sangje. Judging from the form of salutation, the status of these two Sangjes are the same. Yet, the object of belief is Gu-cheon Sangje as the highest God, while Ok-hwang Sangje is stipulated as the one who has wielded a true law succeeding to the Gu-cheon Sangje's will. The religious term of Yang-wui Sangje don't imply meaning Gu-cheon Sangje and Ok-hwang Sangje are the same rank. Yang-wui Sangje is the term expresses Sangje in two Godship and involves the orthodox heritage of Daesoonjinrihoe. Along with An Introduction to the Study of the Outlook on the Highest Ruling Entity in Daesoonjinrihoe (I), this article is written, while giving a thought to construct the religiography on the highest God in Daesoonjinrihoe. I hope this article accompanied with the previous one, can be contributed to the fertilization of the soil in the field of Daesoon religious studies.

• 대순사상논총
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• 제46집
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• pp.189-234
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• 2023

오늘날 서구 윤리학에서 규범윤리 중 하나인 덕윤리는 아리스토텔레스의 덕이론에 기반하고 있다. 덕윤리는 행위보다 행위자의 성품(性品)을 중심에 두며 의무론과 공리주의 같은 외면적 행위 기준의 도덕이론이 갖는 문제점을 해소하는 윤리관으로 평가받고 있다. 이글은 덕의 속성이나 개념을 알아보는 덕이론의 입장에서 강증산 성사(聖師)의 덕의 특징을 살펴보고자, 아리스토텔레스의 덕과의 비교를 목적으로 한다. 먼저 덕의 속성으로서 두 사상의 덕은 형이상학적 기원으로 영혼과 도가 있고, 각각 이성및 마음과 관련하여 작용한다. 아리스토텔레스의 덕은 인간 이성의 탁월한 성품을 가리키고 이에 대해 강증산의 덕은 청정한 본질로 회복하려는 마음 수행에서 나오는 성품이라 할 수 있다. 덕은 그것이 추구하는 좋은 삶 개념을 포함하여 설명하게 되는데 이때 좋은 삶으로서 각각 에우다이모니아와 해원상생으로 대응된다. 아리스토텔레스의 에우다이모니아를 실현하기 위한 성품으로 덕은 중용(中庸)의 덕을 강조하며, 강증산의 해원상생을 실현하기 위한 성품으로서 덕은 무자기(無自欺)와 대인대의(大仁大義)의 덕이 있다. 두 덕이론의 유사점은 덕이 인간으로서 목적을 다하기 위해 좋은 삶을 실현하는 성품으로서 목적론적 성격이 있다는 것이다. 이와 관련하여 공통적으로 실천적 지혜와 지속적인 덕 함양의 과정이 필요하다. 또 다른 유사점으로 덕에 중(中)을 추구하는 의미가 있다는 것이다. 차이점은 덕의 속성과 관련하여 영혼과 도는 다른 측면의 개념이며 아리스토텔레스의 덕은 강증산의 덕과 달리 천부적이며 본성적인 것이 아니라는 차이가 있다. 또한 좋은 삶으로서 에우다이모니아가 인간사회에 국한된 좋은 삶이라면 해원상생은 인간, 신, 만물을 대상으로 하는 좋은 삶이라는 점에서 차이가 있다. 아리스토텔레스의 중용의 덕이 이성적인 면이 강조된다면 강증산의 무자기와 대인대의의 덕은 이성적 측면 외에도 마음을 통해 남을 이해하는 정서적인 면과 상호간 관계적 덕의 측면이 있다는 면이다.

• 대순사상논총
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• 제49집
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• pp.93-125
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• 2024

본고에서는 현대사회의 급속한 변화 속에 대순사상의 강령에 대한 재해석과 그에 따른 확장적 적용이 필요하다는 문제의식에서 출발한다. 대순사상은 조선사회가 내우외환 속에 근대화되는 과정과 맞물려있다. 당시에 민족생존이나 반봉건주의의 기치 하에 민생, 민중, 민권의 근대의식이 고양되었다. 근대의식은 계도나 교화를 통해 조선사회의 총체적 삶 전반에 스며들었다. 대순사상의 강령도 이러한 총체적 삶과 관련한 문화적 담론에서 접근될 수 있다. 조선사회는 근대화의 시대적 전환 속에 민족적 전통을 중건(重建)해야 하는 시대적 과업에 직면하고 있었다. 당시에 민족생존이나 반봉건주의의 기치 하에 민생, 민중, 민권의 근대의식이 고양되었다. 근대의식은 계도나 교화를 통해 조선사회의 총체적 삶 전반에 스며들었다. 문화적 담론에 관한 대순사상의 조감도에서 민족생존이나 반봉건주의를 위한 계도나 교화의 등고선을 찾아가면서 조선의 문화적 공간을 조망하고 그 문화생태주의적 좌표를 알아낼 수 있다. 여기에서 문화생태주의란 문화의 심층적 바탕에 인간과 자연의 생태적 관계가 깔려있다는 전제 하에 생태주의의 문제의식을 인문학적으로 특화한 사조를 가리킨다. 생태주의적 좌표는 민생, 민중 및 민권의 동일선상에서 공감, 공생, 화합 등의 열린 공간을 제시한다. 대순사상은 기본적으로 인간의 존재와 가치에 기초한다. 그 강령에는 조선사회의 근대화에서 삶 전반의 총체적 모습 속에 세계의 실재에 참여하고 실천하는 합목적성과 가치지향성이 자리잡고 있다. 존재의 합목적성이 천지공사의 세계와 관련된다면 가치의 지향성은 지상선경의 경계와 관련된다. 이러한 강령의 문화생태주의적 조감도에는 현실적 실천과 이상적 바람의 격차를 원만하게 해소하고 전통적 사회와 근대적 사회를 조화롭게 화해하는 탈경계적 지평이 열려있다. 그 지평에서 민생, 민중 및 민권의 입체적 관계에 기반한, 현세적인 통합적 삶이 온전하게 충족될 수 있다. 즉 근대사회의 변화가능성에 맞추어 천지공사의 실천가능성을 도모하고 지상선경의 지속가능성을 모색하는 것이다. 특히 지상선경의 통합적 차원은 선천시대에서 후천시대로 나아가는 문화정신의 총체적 흐름으로 특징지을 수 있다. 지성선경의 경계는 현실의 세계를 탈출하려는 도피처가 아니라 당면한 현실적 공간 속에 또 하나의 현실의 공간을 자각적으로 창출한 근대의식의 산물이다. 이는 현세주의적 염원을 투영한 결과로서, 현대적 의미에서 현실과 이상을 함께 아우르는 탈경계적인 문화생태주의적 조감도에서 조망할 수 있다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.