• Title/Summary/Keyword: change of composition

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Change of Ratio of Onchungeum Composition Induces Different G1 Arrest Mechanisms in Hep3B Cells (온청음(溫淸飮)의 조성 용량변화가 Hep3B 세포의 G1 arrest 기전에 미치는 영향)

  • Goo, In-Moo;Kim, Gil-When;Shin, Heung-Mook
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.5
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    • pp.1250-1255
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    • 2008
  • Onchungeum(OCE), a herbal formula, has been used for treatment of anemia, discharging blood and skin diseases. In the previous study, we investigated the anti-cancer effect of OCE by G1 arrest of the cell cycle in human hepatocarcinoma cells, Hep3B cells. In this study, it was examined that the difference of anti-proliferative mechanisms by change in the ratio of OCE composition (OCE I) in Hep3B cells. Treatment of OCE I exhibited a relatively strong anti-proliferative activity and caused various morphological changes such as membrane shrinkage and cell floating. In addition, OCE-I arrests the cell cycle at G1 phase, which was associated with the down-regulation of cyclin D1 and Cdk6 expressions. The G1 arrest was also associated with the induction of Cdk inhibitors p27 and p21. Moreover, both p21 and p27 were detected by immunoprecipitation with anti-Cdk4 and anti-Cdk2 antibodies in OCE I-treated cells but in case of OCE, p21 did not make any complexes with Cdk4 and Cdk2. These results suggest that the change in the ratio of OCE composition might induce different mechanisms in anti-cancer efficacy of OCE, which may confer characteristic principles in oriental medical formula.

Changes in Forest Disturbance Patterns from 1976 to 2005 in South Korea

  • Park, Pil Sun;Lee, Kyu Hwa;Jung, Mun Ho;Shin, Hanna;Jang, Woongsoon;Bae, Kikang;Lee, Jongkoo;Lee, Don Koo
    • Journal of Korean Society of Forest Science
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    • v.98 no.5
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    • pp.593-601
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    • 2009
  • Forest disturbances including forest fire, insect pests and diseases, landslides, and forest conversion from 1976 to 2005 were investigated to trace the changes of major forest disturbance agents and their characteristics over time in accordance with changes in natural and social environment in South Korea. While the damaged area by insect pests and diseases continuously decreased for the past 30 years, damaged areas by forest fire and landslide were fluctuating through years. The interval of large forest fires has become shorter with increased tree volume. The precipitation between January and April were significantly correlated with large fire occurrences as Pearson's correlation coefficient -0.400 (P=0.029). The composition of major insect pests and diseases damaging Korean forests has been changed continuously, and become more diversified. While damages by pine caterpillar (Dendrolimus spectabilis) and pine needle gall midge (Thecodiplosis japonensis) decreased, damage by introduced pests has been more serious recently. The change of precipitation pattern that brought more localized heavy rain or powerful typhoon resulted in the recent increase in landslide areas. The major land uses to induce forest conversion have been changed, reflecting the changes in industrial structure in South Korea as agriculture and mining in 1970s, mining and golf ranges classified in pasture in 1980s, and road and housing construction in 1990s and 2000s. Changes in forest disturbance patterns in South Korea show that a country's industrial development is jointly working with global warming on forest stand dynamics. Altering energy structure and land use pattern induced by industrial development accumulates forest volume and reforms microenvironments on forest floor, interacting with climate change, inducing shorter interval of large forest fire and changes in major species composition of forest insect pests and diseases.

Effect of Non-Metallic Inclusions and Hot Rolling Process Parameters on Hydrogen Induced Cracking of Linepipe Steels (라인파이프 강재의 수소유기균열에 미치는 열간압연 공정변수의 영향)

  • Koh, Seong Ung;Jung, Hwan Gyo;Kang, Ki Bong
    • Korean Journal of Metals and Materials
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    • v.46 no.4
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    • pp.257-266
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    • 2008
  • AHydrogen induced cracking (HIC) was phenomenologically studied in terms of the effect of nonmetallic inclusions and hot rolling process parameters. By comparing the level of non-metallic inclusions in two different kinds of commercial grade steels having different HIC resistance, the role of non-metallic inclusions in HIC occurrence was investigated. Change in inclusion morphology and distribution during hot rolling was also studied throughout slab, rolling at austenite recrystallization region (roughing mill; RM) and rolling at austenite non-recrystallization region (finish mill; FM). In addition, the contribution of RM and FM parameters to HIC was investigated from the standpoint of change in inclusion morphology during hot rolling processes. As a result, HIC was closely related to the separation of large complex inclusion during hot rolling process. Large complex inclusions originated from the improper Ca treatment, after which equilibrium composition of slag should have resulted in eutectoid composition. By controlling the equilibrium slag composition equivalent to eutectoid one, HIC resistance could be improved due to the reduced size of inclusions. In addition, change in reduction/pass in RM had an effect on HIC resistance of steels while that in FM did not. Increase in the reduction/pass in the latter stage of RM improved HIC resistance of steels by enhancing the void enclosure around inclusions.

The Change of Beach Sediment Composition and Geography by Typhoon (Naa Beach, East Sea) (태풍에 의한 해빈 퇴적물 조성 및 지형 변화(동해, 나아해빈))

  • Lee, Yeon-Gyu;Shin, Hyeon-Ok;Lee, Jeong-Sup;Park, Il-Heum;Choi, Jeong-Min
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.8 no.3
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    • pp.122-133
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    • 2005
  • The change of surface sediment composition, shoreline and transection of geography were studied to investigate the Typhoon(Maemi) effect in Naa Beach located in the south area of East sea. In the backshore the volume of gravel is do creased, and increased in the volume of sand. The erosion in the sediment occurred to 4 m in the thickness and effected to 10 m in depth. And the coastline retreated to 12 m after typhoon. During typhoon conditions, higher amplitude waves deepen the wave base, causing much of the lower beach face and the offshore. The upper beach face is extensively eroded during typhoon and sand sediment is redeposited.

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The Change in Content of Constitutive Lipid and Fatty Acid of Pacific Saury during Natural Freezing Dry(Kwa Mae Kee) (꽁치 자연동결건조(과메기)중 지방함량과 지방산 조성 변화)

  • 오승희;김덕진
    • The Korean Journal of Food And Nutrition
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    • v.8 no.3
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    • pp.239-252
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    • 1995
  • The results which were examined changes In contents of constitutive lipid and fatty acid during the natural drying of Pacific Saury were as follows. During the natural drying of Pacific Saury, offal lipid and moisture contents gradually decreased. In the survey of rancidity degree extracted lipid of Pacific Saury, peroxide value was gradually Increased, TBA and acid value were radically increased thereafter 9 days of drying. Neutral lipid, phospholipid and glycolipid contents of total lipid were 95%, 4% and 2%, respectively, and in the neutral lipid, content of TG was more than 90%, and in the phospholipid, contents of PC and PE were 45∼85%, 27∼34%, respectively. Fatty acid composition of total lipid was substantially higher in C18:0 and C20:1, C22:1, C22:6 contents and fatty acid composition of neutral lipid was higher In C22:1, C22:1, contents and fatty acid composition of phospholipid was the highest in C22:6 content. In the fatty acid composition of glycolipid, monounsaturated fatty acid content has substantially higher, C16:0 content was gradually Increased In saturated fatty acid and C22:1 content was gradually decreased in monounsaturated fatty acid. It showed that fatty acid composition of triglyceride has higher in monounsaturated fatty acid content and contents of C20:1, C22:1 was gradually decreased.

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Diet composition and feeding strategy of John Dory, Zeus faber, in the coastal waters of Korea

  • Kim, Han Ju;Kim, Hyeong-Gi;Oh, Chul-Woong
    • Journal of Ecology and Environment
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    • v.44 no.1
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    • pp.54-61
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    • 2020
  • Background: Most fish undergo prey switch from juvenile to adult. It is thought that slightly different feeding habits occur among adult fishes due to growth, spawning, habitat change, and so on. Therefore, the diet of the John Dory Zeus faber (≥ 24 cm TL) was studied in the coastal waters of Korea by analysis of stomach contents, with comparison by season and size class of diet composition and prey diversity. Monthly samples were taken from February 2017 to January 2018. Results: The results showed that the John Dory was a piscivorous predator, and pisces had occupied 82.3% of IRI%. Trichiurus lepturus and Trachurus japonicus were important preys in all size classes and seasons. Diet composition differed among the size classes and seasons (Chi-square test, P < 0.05). As body size of Z. faber increased, the occurrence of benthic fish (Glyptocephalus stelleri) tended to increase. The seasonal prey composition also changed depending on the abundant species of each season. Conclusions: Z. faber is a piscivorous predator. The consumption habits of Z. faber appear to different results by their size and seasons. This study suggests that Z. faber could be considered an opportunistic predator.

Effect of Dietary Lipid Sources on Body Fatty Acid Composition of Chinese Longsnout Catfish Leiocassis longirostris

  • Choi, Jin;Lee, Sang-Min
    • Fisheries and Aquatic Sciences
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    • v.18 no.4
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    • pp.359-365
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    • 2015
  • We investigated the effects of dietary lipid sources on growth and fatty acid composition of juvenile Chinese longsnout catfish. Triplicate groups of fish (initial average weight, 3.8 g) were fed four diets containing either fish oil (FO), soybean oil (SO), linseed oil (LO) and lauric acid (LA) for 10 weeks. There were no differences among the groups in body weight, feed intake, feed efficiency, protein efficiency ratio, and body proximate composition of fish fed the diets containing different lipid sources (P > 0.05) during the study. However, fatty acids compositions of the whole body were influenced by dietary lipid source. Fish fed the SO diet had high concentration of linoleic acid, whereas those of fish fed the LO diet were rich in linolenic acid and arachidonic acid. Fish fed the FO diet had significantly (P < 0.05) higher levels of monounsaturated fatty acids such as 18:1n-9 and 20:1n-9 than those of fish fed the SO and LO diets. Eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) composition of body were not influenced by dietary lipid source. The results suggest that each of FO, SO, LO or LA can be used as a lipid source in the diets of Chinese longsnout catfish without any negative effects on growth and feed utilization and these data demonstrate the potential impact which dietary fat composition can change the body fatty acid profile.

Carbon and Oxygen Isotope Studies of the Paleozoic Limestones from the Taebaegsan Region, South Korea (한국(韓國) 태백산지역(太白山地域)에 분포(分布)하는 고생대(古生代) 석회암(石灰岩)의 탄소(炭素)와 산소(酸素) 동위원소(同位元素)에 관(關)한 연구(硏究))

  • Kim, Kyu Han
    • Economic and Environmental Geology
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    • v.13 no.1
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    • pp.21-27
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    • 1980
  • ${\delta}^{13}C$ and ${\delta}^{18}O$ values were determined for the Paleozoic limestones (Great Linestone Series) from the Taebaegsan region and the age-unknown limestones (Janggun Formation) from the Janggun mine, Korea. Limestones of the Great Limestone Series exhibit a range of carbon isotopic composition from -4.5 +1.3‰ with a mean ${\delta}^{13}C$ value of -1.1‰, relative to the PDB standard, and of oxygen isotpic composition from +8.8 to +23.3‰ with a mean ${\delta}^{18}O$ value of +16.0‰, relative to the SMOW, falling into the normal marine limestone range according to Keith and Weber (1964), and Degens and Epstein(1964). Carbon isotopic composition of limestones of the Great Limestone Series becomes progressively lighter from Pungchon limestone of middle Cambrian age to mid-Ordovician Maggol limestone, possibly due to change in depositional environment in the Taebaegsan basin. Variation in isotopic composition of limestones from Hwajeol to Dumugal formation offers the possibility or deposition in shallow sea environment, in which fresh waters were added in several stages. Janggun limestone of unknown age may be corelated with the Paleozoic limestones of Great Limestone Series as infered from the istopic composition ranging from -2.8 to + 0.7‰ of ${\delta}^{13}C$ and +13.4 to +22.4‰ of ${\delta}^{18}O$.

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Effects of Postpartum Exercise on Pelvic Muscle Contraction, Body Composition, and Physical Fitness of the Postpartum Mother (산후운동이 산욕부의 질수축압, 신체조성, 체력에 미치는 효과)

  • Lee, Sun-Ok
    • Women's Health Nursing
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    • v.10 no.3
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    • pp.244-251
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    • 2004
  • Purposes: This study was to examine the effects of postpartum exercise on pressure of the pelvic muscle contraction, body composition and physical fitness of postpartum mothers. Method: A nonequivalent pre-test, post-test control group study was conducted. Fifty-two postpartum mothers(experimental group, 26; control group, 26) admitted to a postpartum ward in a Busan mother-baby clinic were recruited. Data was analyzed using mean, $x^2$-test, and t-test by SPSS 10.0. Result: Body fat mass(t=-3.196. p= .002), body fat rate (t=-3.831, p= .000), and fat distribution(t=-3.026, p= .004) of body composition increased significantly in the experimental group after the postpartum exercise as compared with the control group. After an 8 week exercise program, the pressure of the pelvic muscle contraction in the experimental group was significantly higher than in the control group(t=3.329, p=.002). In the change of physical fitness, grip strength of the hand, back muscle strength, and trunk flexion forward were not significantly changed, but trunk backward extension in the experimental group significantly increased(t=1.950, p=.050). Conclusion: Postpartum exercise affects pelvic muscle contraction, body composition, and physical fitness of the postpartum mother.

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A Study on Effect of Obesity Management Program for Elementary School Student (초등학생 비만교실 운영의 효과)

  • Eun, Young-Jun;Song, Yun-Kyung;Lim, Hyung-Ho;Choi, Seung-Peom
    • Journal of Korean Medicine for Obesity Research
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    • v.5 no.1
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    • pp.109-119
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    • 2005
  • Objective : The purpose of this study was to evaluate the effectiveness of obesity management program on height and body Composition and its correlationship with constitution types, obesity grade, and the frequency of attendance among the elementary school student. Methods : The subjects consisted of 75 elementary school student who participated in the obesity management program and got the constitution type test and height and height-body composition test(2 times). The program contained proper lifestyle education, dietary education, exercise and so on once a week for nine weeks. The data were analyzed with SPSS 12.0 for Windows. Results : Height and body composition were significantly improved at the post-test. Among constitution types, obesity grade, and the frequency of attendance, obesity grade by BMI was correlated with the change of height and body composition. Conclusion : These results provides evidence that obesity management program is effective in improving height and body composition for elementary school student.

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