• 제목/요약/키워드: chain formation

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Global Value Chain Formation and Human Capital: Case of Korea and ASEAN

  • Li, Jia-En;Choi, Young-Jun
    • Journal of Korea Trade
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    • 제25권6호
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    • pp.126-142
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    • 2021
  • Purpose - This study discusses the effects of human capital in the formation of GVC linkages. We also investigate GVC intensity between Korea and ASEAN. Design/methodology - To solve the doubling-counting problem in evaluating comparative advantage, RCA has been re-computed using domestic value-added (henceforth RCA_VA) at the country-sector level instead of value of trade. The impact of human capital on GVC intensity was empirically analyzed by establishing a panel data set with four industries (ISIC Rev. 4) in eight ASEAN countries from 2005 to 2015 from OECD-TiVA and WDI. Findings - The empirical results show that human capital has a negative effect on GVC intensity in the agriculture and manufacture industries, while it has a positive effect in the service and information industries. The results do not mean that low human capital is a barrier and inefficient to GVC linkages. Low Value-added activities may be more profitable to some emerging countries. These findings suggest that it is important to accurately identify the competitive elements to increase gains from trade under the GVC. Also, it shows that comparative advantages can be misled by an RCA index evaluated in trade volume under the GVC. Originality/value - This study highlights the importance of human capital as a factor for the efficient formation of Global Value Chain (GVC). This study has different from the literature in analyzing the role of human capital in formation of linkage of the GVC. And we clarify the changing patterns of trade by removing the double-counting problem under the GVC.

Undecanoic Acid, Lauric Acid, and N-Tridecanoic Acid Inhibit Escherichia coli Persistence and Biofilm Formation

  • Jin, Xing;Zhou, Jiacheng;Richey, Gabriella;Wang, Mengya;Choi Hong, Sung Min;Hong, Seok Hoon
    • Journal of Microbiology and Biotechnology
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    • 제31권1호
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    • pp.130-136
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    • 2021
  • Persister cell formation and biofilms of pathogens are extensively involved in the development of chronic infectious diseases. Eradicating persister cells is challenging, owing to their tolerance to conventional antibiotics, which cannot kill cells in a metabolically dormant state. A high frequency of persisters in biofilms makes inactivating biofilm cells more difficult, because the biofilm matrix inhibits antibiotic penetration. Fatty acids may be promising candidates as antipersister or antibiofilm agents, because some fatty acids exhibit antimicrobial effects. We previously reported that fatty acid ethyl esters effectively inhibit Escherichia coli persister formation by regulating an antitoxin. In this study, we screened a fatty acid library consisting of 65 different fatty acid molecules for altered persister formation. We found that undecanoic acid, lauric acid, and N-tridecanoic acid inhibited E. coli BW25113 persister cell formation by 25-, 58-, and 44-fold, respectively. Similarly, these fatty acids repressed persisters of enterohemorrhagic E. coli EDL933. These fatty acids were all medium-chain saturated forms. Furthermore, the fatty acids repressed Enterohemorrhagic E. coli (EHEC) biofilm formation (for example, by 8-fold for lauric acid) without having antimicrobial activity. This study demonstrates that medium-chain saturated fatty acids can serve as antipersister and antibiofilm agents that may be applied to treat bacterial infections.

포도주 효모에 의한 중간크기의 지방산 생성 (Formation of Medium Chain Fatty Acid by Wine Yeasts)

  • 이수오
    • 한국식품과학회지
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    • 제21권6호
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    • pp.832-837
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    • 1989
  • 포도주 발효에 사용되는 호모균주 12종을 Murphy배지에 배양하여 중간크기의 지방산(MCFA)의 생성을 분석하였고 발효조건에 따라 그 생성량을 관찰하였다. 특히 발효력이 강한 Saccharomyces cerevisiae에 속하는 균주들은 발효초기에 decanoic acid를 약 21-26mg/1 생성하였고 발효 후기에는 약 5-10mg/1로 감소하였다. 발효조건에서 볼 때 MCFA의 생성은 온도가 높을수록 감소하였고 당함량이 클수록 증가하였으며 또한 탄산가스의 존재 하에서도 증가하였다.

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Aromatic Formation from Vinyl Radical and Acetylene. A Mechanistic Study

  • Natalia, Debby;Indarto, Antonius
    • Bulletin of the Korean Chemical Society
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    • 제29권2호
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    • pp.319-322
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    • 2008
  • The viability of acetylene addition in each step of aromatic formation initiated by vinyl radical and acetylene also with its competition with structure rearrangement is investigated by determining optimal geometries and barrier and reaction energies using quantum mechanical methods. In principle, the addition reaction has more difficult in term of free energy and enthalpy compared to geometry arrangement. Under combustion conditions, i.e. T = 1200 K, acetylene addition is unfavorable mechanism as the barrier energy values rise much higher than that of geometry arrangement. However, in longer chain hydrocarbon case, e.g. n-CxHx+1 where x ³ 8, C-C bond rotation is rather difficult and requires high energy to form a ring structure, elongation chain is preferable.

Formation Dynamics of Carbon Atomic Chain from Graphene by Electron Beam Irradiation

  • Park, Hyo Ju;Lee, Zonghoon
    • Applied Microscopy
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    • 제48권4호
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    • pp.126-127
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    • 2018
  • Carbon has numerous allotropes and various crystalline forms with full dimensionalities such as diamond, graphite, fullerenes, and carbon nanotubes leading a wide range of applications. Since the emerge of graphene consisting of a single atomic layer of carbon atoms, a fabrication of all-carbon-based device with combination of one-, two-, and three-dimensional carbons has become a hot issue. Here, we introduce an ultimate one-dimensional carbon atomic chain. Carbon atomic chains were experimentally created by removing atoms from monolayer graphene sheet under electron beam inside transmission electron microscope (TEM). A series of TEM images demonstrate the dynamics of carbon atomic chains over time from the formation, transformation, and then breakage.

Markov Chain of Active Tracking in a Radar System and Its Application to Quantitative Analysis on Track Formation Range

  • Ahn, Chang-Soo;Roh, Ji-Eun;Kim, Seon-Joo;Kim, Young-Sik;Lee, Juseop
    • Journal of Electrical Engineering and Technology
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    • 제10권3호
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    • pp.1275-1283
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    • 2015
  • Markov chains for active tracking which assigns additional track illuminations evenly between search illuminations for a radar system are presented in this article. And some quantitative analyses on track formation range are discussed by using them. Compared with track-while-search (TWS) tracking that uses scan-to-scan correlation at search illuminations for tracking of a target, active tracking has shown the maximum improvement in track formation range of about 27.6%. It is also shown that the number and detection probability of additional track beams have impact on the track formation range. For the consideration of radar resource management at the preliminary radar system design stage, the presented analysis method can be used easily without the need of Monte Carlo simulation.

TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation

  • Eunju Kim;Hyunchu Cho;Gaeul Lee;Heawon Baek;In Young Lee;Eui-Ju Choi
    • Molecules and Cells
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    • 제46권7호
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    • pp.430-440
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    • 2023
  • Linear ubiquitin chain assembly complex (LUBAC) is a ubiquitin E3 ligase complex composed of HOIP, HOIL-1L, and SHARPIN that catalyzes the formation of linear/M1-linked ubiquitin chain. It has been shown to play a pivotal role in the nuclear factor (NF)-κB signaling induced by proinflammatory stimuli. Here, we found that tumor susceptibility gene (TSG101) physically interacts with HOIP, a catalytic component of LUBAC, and potentiates LUBAC activity. Depletion of TSG101 expression by RNA interference decreased TNFα-induced linear ubiquitination and the formation of TNFα receptor 1 signaling complex (TNF-RSC). Furthermore, TSG101 facilitated the TNFα-induced stimulation of the NF-κB pathway. Thus, we suggest that TSG101 functions as a positive modulator of HOIP that mediates TNFα-induced NF-κB signaling pathway.

Dammarane계(係) Triterpenoid의 질량분광분석(質量分光分析) (Mass Spectrometry of Dammarane Triterpenoids)

  • 한병훈;김제훈;지형준
    • 생약학회지
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    • 제10권2호
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    • pp.55-59
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    • 1979
  • Mass spectra of the dammarane triterpenes having open side chain and $C_{20}-C_{25}-epoxy$ side chain were measured. Principal fragment ions were assigned and plausible mechanisms for the formation of the fragment ions were proposed. In general, the triter-penoids of $C_{20}-C_{25}-epoxy$ side chain. produce $h_{1}-species$ fragment ions by the deletion of side chain at $C_{20}-C_{22}$ bond and open side chain triterpenoids produce $h_{2}$ species fragmentions whose mass numbers are higher by two mass unit than those of $h_{1}$ species. The mass number of h species fragment ions will serve as the diagnostic tool for the elucidation of side chain structure of tetracyclic triterpenoids.

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폴리아크릴로니트릴의 構造變化에 있어서의 動力學的 및 統計學的 硏究 (Kinetics and Statistics of Structural Changes in Polyacrylonitrile)

  • 노익삼
    • 대한화학회지
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    • 제10권1호
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    • pp.25-31
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    • 1966
  • 폴리아크릴로니트릴을 加熱할 때 着色과 同時에 構造變化가 있다는 것은 잘 알려진 事實이며 이것은 部分水素化나프틸리딘型環을 形成함에 基因하는 것으로 알려지고 있다. 本硏究는 이와 같은 構造變化의 反應을 動力學的 및 統計學的으로 取扱하여 지금까지 알려지지 않았던 새로운 事實들을 發見하였다. 첫째로 폴리아크릴로니트릴을 加熱할 때의 니트릴基의 減少는 一次反應이라는 것이며 이는 環形成反應이 긴連鎖反應으로 이루어지지 않는다는 것을 말해 주는 것이다. 다시 말하면 環形成時의 kinetic chain length는 極히 짧다는 것이다. 또 本 構造變化는 반드시 分子間反應(架橋結合)이 아니드라도, 일어날 수 있다는 것을 證明했다. 둘째로 環形成으로 니트릴基가 減少할 때 19~22%의 니트릴基가 殘存한다는 것이며 이를 統計學的으로 解析해본 結果 19.2%라는 計算値를 얻었으며 이는 實驗値와 잘 맞는 數値이다.

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