• 산업공학
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• 제25권2호
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• pp.241-254
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• 2012

This paper studies the relationship between SCM(Supply Chain Management) metrics and corporate value (Tobin's Q) for manufacturing and wholesale/retail firms in Korea. Specifically, the multiple regression analysis is used to investigate the relationships 1) between inventory level, inventory turns, and days of inventory and Tobin's Q and 2) between cash-to-cash (C2C) cycle time including its components such as days of inventory, days sales outstanding, and days payable outstanding and Tobin's Q. The results indicate that there exist statistically significant negative relationships between inventory levels and days of inventory (DOI) and Tobin's Q. Also, we found that there exist commonly known negative correlations between days of raw materials inventory and days of work in process (WIP) inventory and Tobin's Q. For the C2C cycle time, we found that there -exists a statistically significant negative relationship between the C2C cycle time and Tobin's Q. Also, we found that there exist commonly known correlations between the two components of C2C cycle time and Tobin's Q such as the negative for DOI and days sales outstanding. This study clearly shows the negative relationship in general between inventory levels and corporate value and between C2C time and corporate value, and this kind of result has not been found by previous studies in Korea.

• Asian-Australasian Journal of Animal Sciences
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• 제32권6호
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• pp.891-895
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• 2019

Objective: Aim of present study was the set up of a fast and reliable protocol using species-specific markers for the quali-quantitative analysis of DNA and the detection of ruminant biological components in dairy products. For this purpose, the promoter of the gene coding for the ${\alpha}$-lactoalbumin (LALBA) was chosen as possible candidate for the presence of short interspersed nuclear elements (SINEs). Methods: DNA was isolated from somatic cells of 120 individual milk samples of cattle (30), Mediterranean river buffalo (30), goat (30), and sheep (30) and the gene promoter region (about 600/700 bp) of LALBA (from about 600 bp upstream of exon 1) has been sequenced. For the development of a single polymerase chain reaction (PCR) protocol that allows the simultaneous identification of DNA from the four species of ruminants, the following internal primers pair were used: 5'-CACTGATCTTAAAGCTCAGGTT-3' (forward) and 5'-TCAGA GTAGGCCACAGAAG-3' (reverse). Results: Sequencing results of LALBA gene promoter region confirmed the presence of SINEs as monomorphic "within" and variable in size "among" the selected species. Amplicon lengths were 582 bp in cattle, 592 bp in buffalo, 655 in goat and 729 bp in sheep. PCR specificity was demonstrated by the detection of trace amounts of species-specific DNA from mixed sources ($0.25ng/{\mu}L$). Conclusion: We developed a rapid PCR protocol for the quali-quantitative analysis of DNA and the traceability of dairy products using a species-specific marker with only one pair of primers. Our results validate the proposed technique as a suitable tool for a simple and inexpensive (economic) detection of animal origin components in foodstuffs.

• Journal of Microbiology
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• 제43권3호
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• pp.277-284
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• 2005

The avermectins are composed of eight compounds, which exhibit structural differences at three positions. A family of four closely-related major components, A1a, A2a, B1a and B2a, has been identified. Of these components, B1a exhibits the most potent antihelminthic activity. The coexistence of the '1' components and '2' components has been accounted for by the defective dehydratase of aveAI module 2, which appears to be responsible for C22-23 dehydration. Therefore, we have attempted to replace the dehydratase of aveAI module 2 with the functional dehydratase from the erythromycin eryAII module 4, via homologous recombination. Erythromycin polyketide synthetase should contain the sole dehydratase domain, thus generating a saturated chain at the C6-7 of erythromycin. We constructed replacement plasmids with PCR products, by using primers which had been derived from the sequences of avermectin aveAI and the erythromycin eryAII biosynthetic gene cluster. If the original dehydratase of Streptomyces avermitilis were exchanged with the corresponding erythromycin gene located on the replacement plasmid, it would be expected to result in the formation of precursors which contain alkene at C22-23, formed by the dehydratase of erythromycin module 4, and further processed by avermectin polyketide synthase. Consequently, the resulting recombinant strain JW3105, which harbors the dehydratase gene derived from erythromycin, was shown to produce only C22,23-unsaturated avermectin compounds. Our research indicates that the desired compound may be produced via polyketide gene replacement.

• 한국작물학회지
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• 제50권1호
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• pp.60-66
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• 2005

Pod shape of twenty soybean (Glycine max L. Merrill) genotypes was evaluated quantitatively by image analysis using elliptic Fourier descriptors and their principal components. The closed contour of each pod projection was extracted, and 80 elliptic Fourier coefficients were calculated for each contour. The Fourier coefficients were standardized so that they were invariant of size, rotation, shift, and chain code starting point. Then, the principal components on the standardized Fourier coefficients were evaluated. The cumulative contribution at the fifth principal component was higher than $95\%$, indicating that the first, second, third, fourth, and fifth principal components represented the aspect ratio of the pod, the location of the pod centroid, the sharpness of the two pod tips and the roundness of the base in the pod contour, respectively. Analysis of variance revealed significant genotypic differences in these principal components and seed number per pod. As the principal components for pod shape varied continuously, pod shape might be controlled by polygenes. It was concluded that principal component scores based on elliptic Fourier descriptors yield seemed to be useful in quantitative parameters not only for evaluating soybean pod shape in a soybean breeding program but also for describing pod shape for evaluating soybean germplasm.

• 분석과학
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• 제7권4호
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• pp.547-554
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• 1994

국내 자생 담자균, Phellinus ribis부터 ceramide 성분들이 존재함을 확인하고 실리카 컬럼크로마토그래피를 이용하여 분리하고 prep.-TLC로 재차 정제한 다음, 그 구조 및 조성을 검토하였다. FAB-MS 및 GC-MS를 이용하여 그 구성성분을 분석한 결과 지방산 주성분은 hydroxy fatty acid($C_{22:0}$, $C_{25:0}$, $C_{24:0}$, $C_{23:0}$)이고 sphingoid 염기는 (tri-hydroxy-sphinganine 및 동족계열의 아민으로 확인되었다.

• Journal of Microbiology and Biotechnology
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• 제33권6호
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• pp.707-714
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• 2023

Plant-derived insecticide-neonicotinoid insecticides (NIs) played a crucial role in the development of agriculture and food industry in recent years. Nevertheless, synthesis of these nitrogen-containing heterocyclic compounds with an effective and greener routing remains challenging especially to the notion raise of "green chemistry" and "atom economy". While bio-catalyzed methods mediated by nicotinate dehydrogenase (NDHase) then provide an alternative. The current review mainly focuses on the introduction of sources, components, structure, catalytic mechanism and applications of NDHase. Specifically, NDHase is known as nicotinic acid hydroxylase and the sources principally derived from phylum Proteobacteria. In addition, NDHase requires the participation of the electron respiratory chain system on the cell membrane. And the most important components of the electron respiratory chain are hydrogen carrier, which is mainly composed of iron-sulfur proteins (Fe-S), flavin dehydrogenase (FAD), molybdenum binding protein and cytochromes. Heterologous expression studies were hampered by the plasmid and host with high efficiency and currently only Pseudomonas entomophila L48 as well as Comamonas testosterone was successfully utilized for the expression of NDHase. Furthermore, it is speculated that the conjugate and inductive effects of the substituent group at position 3 of the substrate pyridine ring exerts a critical role in the hydroxylation reactions at position 6 concerning about the substrate molecular recognition mechanism. Finally, applications of NDHase are addressed in terms of pesticide industry and wastewater treatment. On conclusion, this critical review would not only deepen our understanding of the theory about NDHase, but also provides the guideline for future investigation of NDHase.

• Journal of Electrical Engineering and Technology
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• 제12권5호
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• pp.1764-1776
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• 2017

To achieve economic stability, distribution Company as an economic institution should be managed by various processes. In this way, knowledge of different processes is the first step. Furthermore, expectations, outputs, requirement data, and sub-processes should be extracted and determined. Accordingly, to assign the performance responsibility of each process, the decision-making points must be introduced and, the deviation or change in set-points should be investigated into processes. Also, the performance of processes could be monitored by introducing of the sub-indictors. In this study, a practical method is presented for monitoring of reliability and power loss indices from viewpoint components' supply chain into the distribution network. At first, the visibility model of the supply chain is illustrated by focus group and the sub-indicators are extracted for each process of this chain. Then, validation and verification of the sub-indicators are accomplished by the Delphi method and, an information dashboard is presented by confirmed the sub-indicators and statistics methods. Finally, the proposed method is investigated by real data in a typical network and the results are analyzed.

• 대한산업공학회지
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• 제39권4호
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• pp.290-297
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• 2013

The increasing level of operation in high-tech industry is likely to require ever more complex structure in reliability problem. Furthermore, system failures are more significant on society as a whole than ever before. Reliability redundancy optimization problem (RROP) plays a important role in the designing and analyzing the complex system. RROP involves selection of components with multiple choices and redundancy levels for maximizing system reliability with constraints such as cost, weight, etc. Meanwhile, previous works on RROP dealt with system with perfect failure detection, which gave at most a good solution. However, we studied RROP with imperfect failure detection and switching. Using absorbing Markov Chain, we present not a good solution but the optimal one. In this study, the optimal system configuration is designed with warm and cold-standby redundancy for k-out-of-n system in terms of MTTF that is one of the performance measures of reliability.

• 산업경영시스템학회지
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• 제36권4호
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• pp.31-37
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• 2013

In this paper, we develop an efficient approach to solve a continuous review inventory system with a budget constraint when the semi-finished product and optional components are required to be assembled. We are, in particular, interested in a budget constraint that includes a service level. The service cost, such as labor and facility costs, tends to increase as the service level increase, and it makes the problem difficult to solve. Assuming that the reorder point for a semi-finished product is given, we show that the order quantity for the semi-finished product and the order quantity and reorder point for optional components can be determined by minimizing the total cost that includes setup cost, inventory holding cost, and shortage cost. The performance of the proposed approach is tested by numerical examples. By using sensitivity analysis, we conclude that, as the reorder point for semi-finished product increases, the order quantity for semi-finished product increases, whereas the order quantity and reorder point of optional components decreases.

• Steel and Composite Structures
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• 제42권2호
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• pp.151-159
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• 2022

This study discusses a hypothetical method for tracking the propagation damage of Carbon Reinforced Fiber Plastic (CRFP) components underneath vibration fatigue. The High Cycle Fatigue (HCF) behavior of composite materials was generally not as severe as this of admixture alloys. Each fissure initiation in metal alloys may quickly lead to the opposite. The HCF behavior of composite materials is usually an extended state of continuous degradation between resin and fibers. The increase is that any layer-to-layer contact conditions during delamination opening will cause a dynamic complex response, which may be non-linear and dependent on temperature. Usually resulted from major deformations, it could be properly surveyed by a non-contact investigation system. Here, this article discusses the scanning laser application of that vibrometer to track the propagation damage of CRFP components underneath fatigue vibration loading. Thus, the study purpose is to demonstrate that the investigation method can implement systematically a series of hypothetical means and dynamic characteristics. The application of the relaxation method based on numerical simulation in the Artificial Intelligence (AI) Evolved Bat (EB) strategy to reduce the dynamic response is proved by numerical simulation. Thermal imaging cameras are also measurement parts of the chain and provide information in qualitative about the temperature location of the evolution and hot spots of damage.