• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.11a
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• pp.558-561
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• 2001

Vanadium oxide ($VO_{x}$) thin films are very good candidate material for uncooked infrared (IR) detectors due to their high temperature coefficient of resistance (TCR) at room temperature. But, the deposition of $VO_{x}$ thin films showing good electrical properties is very difficult in micro bolometer fabrication process using sacrificial layer removal because of its low process temperature and thickness of thin films less than 1000${\AA}$. This paper presents a new fabrication process of $VO_{x}$ thin films having high TCR and low resistance. Through sandwich structure of $VO_{x}$(100${\AA}$)/V(80${\AA}$)/$VO_{x}$(500${\AA}$) by sputter method and post-annealing at oxygen ambient, we have achieved high TCR more than -2%/$^{\circ}C$ and low resistance less than $10K\Omega$ at room temperature.

• Corrosion Science and Technology
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• v.7 no.6
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• pp.301-306
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• 2008

Surface composite layers of 1.9~2.9 mm in thickness were fabricated by depositing metamorphic powders on a carbon steel substrate and by irradiating with a high-energy electron beam. In the surface composite layers, 48~64 vol.% of $Cr_{2}B$ or $Cr_{1.65}Fe_{0.35}B_{0.96}$ borides were densely precipitated in the austenite or martensite matrix. These hard borides improved the hardness of the surface composite layer. According to the otentiodynamic polarization test results of the surface composites, coatings, STS304 stainless steel, and carbon steel substrate, the corrosion potential of the surface composite fabricated with 'C+' powders was highest, and its corrosion current density was lowest, while its pitting potential was similar to that of the STS304 steel. This indicated that the overall corrosion resistance of the surface composite fabricated with 'C+' powders was the best among the tested materials. Austenite and martensite phases of the surface composites and coatings was selectively corroded, while borides were retained inside pits. In the coating fabricated with 'C+' powders, the localized corrosion additionally occurred along splat boundaries, and thus the corrosion resistance of the coating was worse than that of the surface composite.

• Journal of the Korean Ceramic Society
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• v.42 no.12 s.283
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• pp.833-841
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• 2005

The oxidation resistance and electrical conductivity of various commercial ferritic stainless steels including STS444 were tested in an air atmosphere at $700^{\circ}C$. Crofer22 developed specially for SOFC interconnect was also examined for the aim of comparing with the test results of STS444. Although STS444 exhibited higher oxidation resistance than Corfer22, the electrical conductivity of the scale formed on Crofer22 was higher, indicating that the resistivity of scale formed on Crofer22 is much lower than that of STS444. To gain a better understanding of the relation between oxidation behavior and electrical conductivity, the oxide scales formed on STS444 and Crofer22 were analyzed in terms of the structure, composition, and phase. Consequently, the influence of alloying elements on electrical conductivity of Fe-Cr alloys was discussed.

• Journal of Environmental Health Sciences
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• v.38 no.5
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• pp.415-423
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• 2012

Objectives: This study was performed in order to evaluate antibiotic resistance and analyze the multiple antibiotic resistance of food-borne pathogens isolated from indoor air and an air cleaner at a lunch room in a child care center. Methods: An antibiotic test of food-borne pathogens, including four Staphylococcus aureus and 23 Bacillus cereus was conducted through the disk diffusion method from Clinical and Laboratory Standard Institute. Results: All Staph. aureus was resistant to Ampicillin and Penicillin, while B. cereus was also resistant to Ampicillin, Cefepime and Penicillin. All isolates showed Vancomycin susceptibility but three out of four Staph. aureus and all B. cereus were resistant to Oxacillin. Staph. aureus and B. cereus presented two or more multiple antibiotic resistances. Conclusions: The results indicated that food-borne pathogens isolated from indoor air and an air cleaner at a lunch room in a child care center showed multiple antibiotic resistances. The repeated control of indoor environment quality is required and continuous surveillance of antibiotic resistant strains is demanded.

• International Journal of Naval Architecture and Ocean Engineering
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• v.3 no.1
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• pp.105-110
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• 2011

Some research work on CFD computation of ship motions and added resistance in waves for a high speed trimaran is carried out in this paper. The governing equations, Reynolds Averaged Navier-Stokes and continuity equations are discretized by finite volume method. Volume of fluid method is adopted to deal with the nonlinear free surface. The incident waves are generated from the inflow boundary by prescribing a velocity profile resembling flexible flap wavemaker motions, and the outgoing waves are dissipated inside an artificial damping zone located at the rear part of the wave tank. In this paper, the computed results of ship motion and added resistance for a high speed trimaran are presented. The results of seakeeping experiment for the high speed trimaran carried out in CSSRC towing tank are also presented in this paper. Rather good agreements are shown between the computational and experimental results. The work in this paper provides a numerical tool for the study of seakeeping performance of high speed trimarans.

• Journal of the Korean Society for Heat Treatment
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• v.14 no.3
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• pp.155-159
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• 2001

The thermal shock resistance has been investigated and compared in three hot-work tool steels. The resistance to thermal shock is first of all a matter of good toughness and ductility. Therefore, a proper hot-work tool steel should be characterized by high fracture strength and high temperature toughness. In this study, new test method is proposed to measure the thermal shock resistance. New method is basically based on Uddeholm' thermal shock test but some modification has been properly applied. Based on these results, some critical temperature($T_{fractures}$) at which fracture occur can be measured to characterize the thermal resistance of the materials. The specific values of ${\Delta}T$, the temperature difference between holding temperature and $T_{fractures}$, has been successfully used as a measure of the thermal shock resistance in this study, the results showed that the thermal shock method used in this study was properly modified.

• Journal of Korean Society on Water Environment
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• v.22 no.1
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• pp.17-22
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• 2006

This study is about backwash condition and membrane fouling at continuous coagulation/ultrafiltration process in water treatment. The capacity of pilot plant was $0.06m^3/d$. The result of the test, Backwash cycle time and duration time had a significant effect on the efficiency of system and backwash. Backwash duration time was determined to be fixed in 30 seconds for the system with more than 95% recovery rate, It needed 30 minute backwash frequency. During the continuous operation, membrane fouling was analyzed by determining the filtration resistance ($R_i$) and cake layer resistance ($R_c$). At the initial stage, filtration resistance highly influenced the fouling behavior. But after 1.5 hours, cake layer resistance became more important than filtration resistant.

• Progress in Superconductivity and Cryogenics
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• v.24 no.4
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• pp.40-45
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• 2022

The electrical/thermal stabilities and magnetic field controllability of a no-insulation (NI) high-temperature superconducting magnet are characterized by contact resistance between turn-to-turn layers, and the contact resistance characteristics are determined by properties of conductor surface and winding tension. In order to accurately predict the electromagnetic characteristics of the NI coil in a design stage, it is necessary to control the contact resistance characteristics within the design target parameters. In this paper, the contact resistance and critical current characteristics of a rare-earth barium copper oxide (REBCO) conductor were measured to analyze the effects of surface treatment conditions (roughness and oxidation level) of the copper stabilizer layer in REBCO conductor. The test samples with different surface roughness and oxidation levels were fabricated and conductor surface analysis was performed using scanning electron microscope, alpha step surface profiler and energy dispersive X-ray spectroscopy. Moreover, the contact resistance and critical current characteristics of the samples were measured using the four-terminal method in a liquid nitrogen impregnated cooling environment. Compared with as-received REBCO conductor sample, the contact resistance values of the REBCO conductors, which were post-treated by the scratch and oxidation of the surface of the copper stabilizer layer, tended to increase, and the critical current values were decreased under certain roughness and oxidation conditions.

• Experimental and Molecular Medicine
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• v.54
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• pp.1236-1249
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• 2022

Acquired resistance to inhibitors of anaplastic lymphoma kinase (ALK) is a major clinical challenge for ALK fusion-positive non-small-cell lung cancer (NSCLC). In the absence of secondary ALK mutations, epigenetic reprogramming is one of the main mechanisms of drug resistance, as it leads to phenotype switching that occurs during the epithelial-to-mesenchymal transition (EMT). Although drug-induced epigenetic reprogramming is believed to alter the sensitivity of cancer cells to anticancer treatments, there is still much to learn about overcoming drug resistance. In this study, we used an in vitro model of ceritinib-resistant NSCLC and employed genome-wide DNA methylation analysis in combination with single-cell (sc) RNA-seq to identify cytidine deaminase (CDA), a pyrimidine salvage pathway enzyme, as a candidate drug target. CDA was hypomethylated and upregulated in ceritinib-resistant cells. CDA-overexpressing cells were rarely but definitively detected in the naïve cell population by scRNA-seq, and their abundance was increased in the acquired-resistance population. Knockdown of CDA had antiproliferative effects on resistant cells and reversed the EMT phenotype. Treatment with epigenome-related nucleosides such as 5-formyl-2'-deoxycytidine selectively ablated CDA-overexpressing resistant cells via accumulation of DNA damage. Collectively, our data suggest that targeting CDA metabolism using epigenome-related nucleosides represents a potential new therapeutic strategy for overcoming ALK inhibitor resistance in NSCLC.

• Journal of Surface Science and Engineering
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• v.51 no.6
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• pp.381-386
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• 2018

In this study, plasma electrolytic oxidation (PEO) method was used to from anodic oxide films on Al alloy and their resistance and morphological characteristics were investigated as a function of film formation voltage and treatment time. Cross-sectional morphology and composition of the PEO films were analyzed by SEM (Scanning Electron Microscopy) and EDS (Energy Dispersive Spectroscopy). The PEO films showed increased surface roughness and thickness with of film formation voltage and treatment time. The wear resistance was found to be the best for the PEO film formed for 5 min at 500V which is attributed to be denser structure relatively and lower surface roughness.