• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년 학술대회 논문집 정보 및 제어부문
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• pp.139-141
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• 2006

Quantum-dot Cellular Automata (QCA) is one of the most promising next generation nano-electronic devices which will inherit the throne of CMOS which is the domineering implementation technology of large scale low power digital systems. In late 1990s, the basic operations of the QCA cell were already demonstrated on a hardware implementation. Also, design tools and simulators were developed. Nevertheless, its design technology is not quite ready for ultra large scale designs. This paper proposes a new approach which enables the QCA designs to inherit the verification methodologies and tools of CMOS designs, as well. First, a set of disciplinary rules strictly restrict the cell arrangement not to deviate from the predefined structures but to guarantee the deterministic digital behaviors. After the gate and interconnect structures of the QCA design are identified, the signal integrity requirements including the input path balancing of majority gates, and the prevention of the noise amplification are checked. And then the digital logic is extracted and stored in the OpenAccess common engineering database which provides a connection to a large pool of CMOS design verification tools. Towards validating the proposed approach, we designed a 2-bit QCA adder. The digital logic is extracted, translated into the Verilog net list, and then simulated using a commercial software.

• 한국전산구조공학회논문집
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• 제25권1호
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• pp.73-80
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• 2012

대공간 구조물은 형태에 따라 구조물의 설계와 시공에 미치는 영향이 크기 때문에 초기 단계에서의 최적형태 설계가 중요하다. 그러나 기존의 대공간 구조물의 최적형태 설계는 구조엔지니어의 직관이나 경험을 바탕으로 수행되어 왔다. 따라서 본 연구에서는 대공간 트러스 구조물의 체계적인 최적형태 설계를 위해 위상최적화 기법과 Cellular Automata 모델을 이용한 통합프로세서를 제안하고자 한다. 먼저 위상최적화 기법을 이용하여 구조물의 초기 최적형상을 찾고, 다음 단계로 Cellular Automata 규칙에 의해 생성된 구조패턴을 적용하여 대공간 트러스 구조형태를 생성한다. 최종적으로 구조해석을 실시하고 크기최적화를 적용함으로써 설계조건을 만족하는 최적형태를 제안하고자 한다.

• 대한기계학회논문집A
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• 제31권7호
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• pp.792-799
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• 2007

A newly developed cellular metal based on kagome lattice is an ideal candidate for multifunctional materials achieving various optimal properties. Intensive efforts have been devoted to develop efficient techniques for mass production due to its wide potential applications. Since a variety of imperfections would be inevitably included in the realistic fabrication processes, it is highly important to examine the correlation between the imperfections and material strengths. Previous performance tests were mostly done by numerical simulations such as finite element method (FEM), but only for perfect structures without any imperfection. In this paper, we developed an efficient numerical framework using nonlinear random network analysis (RNA) to verify how the statistical imperfections (geometrical and material property) contribute to the performance of general truss structures. The numerical results for kagome truss structures are compared with experimental measurements on 3-layerd WBK (wire-woven bulk kagome). The mechanical strength of the kagome structures is shown relatively stable with the Gaussian types of imperfections.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.78-83
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• 2007

A newly developed cellular metal based on kagome lattice is an ideal candidate for multifunctional materials achieving various optimal properties. Intensive efforts have been devoted to develop efficient techniques for mass production due to its wide potential applications. Since a variety of imperfections would be inevitably included in the realistic fabrication processes, it is highly important to examine the correlation between the imperfections and material strengths. Previous performance tests were mostly done by numerical simulations such as finite element method (FEM), but only for perfect structures without any imperfection. In this paper, we developed an efficient numerical framework using nonlinear random network analysis (RNA) to verify how the statistical imperfections (geometrical and material property) contribute to the performance of general truss structures. The numerical results for kagome truss structures are compared with experimental measurements on 3-layerd WBK (wire-woven bulk kagome). The mechanical strength of the kagome structures is shown relatively stable with the Gaussian types of imperfections.

• Steel and Composite Structures
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• 제5권2_3호
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• pp.193-202
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• 2005

This paper describes recent developments in composite construction and their effect on codified design procedures in the UK. Areas of particular interest include: rules on shear connection, design of beams with web openings, serviceability limits, such as floor vibrations, and fire safe design. The design of cellular beams with regular circular openings now includes generalized rules for web-post buckling, and for the development of in-plane moment in the web-post for asymmetric sections. Closed solutions for the maximum shear force due to limits on web-post bending or buckling are presented. The fire resistance of cellular beams is also dependent on the temperature of the web-post, and for closely spaced openings. It is necessary to increase the thickness of fire protection to the web. For serviceability design of beams, deflection limits and natural frequency and response factor for vibration are presented. It may be necessary to use stricter limits for certain applications.

• Clinical and Experimental Reproductive Medicine
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• 제41권3호
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• pp.97-107
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• 2014

The placenta is a temporary fetomaternal organ capable of supporting fetal growth and development during pregnancy. In particular, abnormal development and dysfunction of the placenta due to cha nges in the proliferation, differentiation, cell death, and invasion of trophoblasts induce several gynecological diseases as well as abnormal fetal development. Autophagy is a catalytic process that maintains cellular structures by recycling building blocks derived from damaged microorganelles or proteins resulting from digestion in lysosomes. Additionally, autophagy is necessary to maintain homeostasis during cellular growth, development, and differentiation, and to protect cells from nutritional deficiencies or factors related to metabolism inhibition. Induced autophagy by various environmental factors has a dual role: it facilitates cellular survival in normal conditions, but the cascade of cellular death is accelerated by over-activated autophagy. Therefore, cellular death by autophagy has been known as programmed cell death type II. Autophagy causes or inhibits cellular death via the other mechanism, apoptosis, which is programmed cell death type I. Recently, it has been reported that autophagy increases in placenta-related obstetrical diseases such as preeclampsia and intrauterine growth retardation, although the mechanisms are still unclear. In particular, abnormal autophagic mechanisms prevent trophoblast invasion and inhibit trophoblast functions. Therefore, the objectives of this review are to examine the characteristics and functions of autophagy and to investigate the role of autophagy in the placenta and the trophoblast as a regulator of cell death.

• 한국주조공학회지
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• 제21권1호
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• pp.41-47
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• 2001

본 연구에서는 FDM법과 CA법을 결합하여 주물의 응고조직성장 예측 프로그램을 개발하였다. 새로운 농도장 분포 알고리즘을 개발하고, 이 결과를 1차원 해석해와 비교하였으며, 이를 2차원 응고조직 및 농도계산에 적용하였다. 3차원 응고조직 예측 해석연구를 통하여 복잡한 형상의 주물에 적용 하였으며, turbine blade형상의 응고조직 시뮬레이션을 통하여 인출속도가 응고조직에 미치는 영향에 대하여 조사하였고, 원하는 주조조업변수를 본 시뮬레이션에 의하여 결정할 수 있으리라 생각된다.

• 한국공간구조학회논문집
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• 제7권3호
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• pp.119-124
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• 2007

장스팬 철골부재설계시, 응력보다는 처짐에 의해 부재단면이 결정되며 이러한 경우 춤을 극대화 할 수 있는 셀룰러 빔이 매우 유리하다. 셀룰러 빔은 웨브의 단면결손으로 인해 웨브의 좌굴강도가 일반형강보의 비해 작아지게 된다. 본 논문에서는 셀룰러 빔의 개구부간격과 직경비, 그리고 개구부직경과 웨브두께비를 주요변수로 비선형 유한요소해석을 통해 웨브포트의 좌굴강도를 평가하였다. 또한 이를 BS5950 Part 1에서 제시하고 있는 기준과 비교분석하였다.

• BMB Reports
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• 제48권3호
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• pp.129-130
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• 2015

Autophagy is a tightly regulated lysosome-mediated catabolic process in eukaryotes that maintains cellular homeostasis. A distinguishable feature of autophagy is the formation of double- membrane structures, autophagosome, which envelopes the intracellular cargoes and finally degrades them by fusion with lysosomes. So far, many structures of Atg proteins working on the autophagosome formation have been reported, however those involved in autophagosome maturation, a fusion with lysosome, are relatively unknown. One of the molecules in autophagosome maturation, TECPR1, has been identified and recently, structural studies on both ATG5-TECPR1 and ATG5-ATG16L1 complexes revealed that TECPR1 and ATG16L1 share the same binding site on ATG5. These results, in combination with supporting biochemical and cellular biological data, provide an insight into a model for swapping ATG5 partners for autophagosome maturation.

• 오토저널
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• 제1권1호
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• pp.28-41
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• 1979

Propane-Air premixed combustible gas was ignited by the conventional current break system inside the open combustion chamber under the atmospheric pressure and the room temperature to measure the flame propagating speed and the burning speed, also to elucidate the history of the propagating flame behavior and wall effects to flame shape by using Ion Gap Method and High Speed Schlieren Photography. The results obtained show that the maximum flame propagating speed and maximum burning speed are approximately 292 cm/sec and 36 cm/sec at the mixture ratio 4.6%, respectively. The cellular flame structures can be observable in the rich mixture region, moreover, the cellular structures become finer, with increasing the mixture strength.