• Proceedings of the KIEE Conference
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• 2006.10c
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• pp.139-141
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• 2006

Quantum-dot Cellular Automata (QCA) is one of the most promising next generation nano-electronic devices which will inherit the throne of CMOS which is the domineering implementation technology of large scale low power digital systems. In late 1990s, the basic operations of the QCA cell were already demonstrated on a hardware implementation. Also, design tools and simulators were developed. Nevertheless, its design technology is not quite ready for ultra large scale designs. This paper proposes a new approach which enables the QCA designs to inherit the verification methodologies and tools of CMOS designs, as well. First, a set of disciplinary rules strictly restrict the cell arrangement not to deviate from the predefined structures but to guarantee the deterministic digital behaviors. After the gate and interconnect structures of the QCA design are identified, the signal integrity requirements including the input path balancing of majority gates, and the prevention of the noise amplification are checked. And then the digital logic is extracted and stored in the OpenAccess common engineering database which provides a connection to a large pool of CMOS design verification tools. Towards validating the proposed approach, we designed a 2-bit QCA adder. The digital logic is extracted, translated into the Verilog net list, and then simulated using a commercial software.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.25 no.1
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• pp.73-80
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• 2012

It is important to design the optimal shape in the initial process because the influences on the design and construction are large according to the shape and pattern of spatial structures. However, the existing optimal shape designs for spatial structure are performed by the designer's intuition and experiences. Therefore, this study proposes the integrated process using the topology optimization and cellular automata model. First, the initial optimal shapes are obtained by using the topology optimization, and then the spatial truss structural patterns are created through the application of cellular automata rules. Finally, the optimal shapes to satisfy the various design conditions are generated by the structural analysis and size optimization.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.7 s.262
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• pp.792-799
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• 2007

A newly developed cellular metal based on kagome lattice is an ideal candidate for multifunctional materials achieving various optimal properties. Intensive efforts have been devoted to develop efficient techniques for mass production due to its wide potential applications. Since a variety of imperfections would be inevitably included in the realistic fabrication processes, it is highly important to examine the correlation between the imperfections and material strengths. Previous performance tests were mostly done by numerical simulations such as finite element method (FEM), but only for perfect structures without any imperfection. In this paper, we developed an efficient numerical framework using nonlinear random network analysis (RNA) to verify how the statistical imperfections (geometrical and material property) contribute to the performance of general truss structures. The numerical results for kagome truss structures are compared with experimental measurements on 3-layerd WBK (wire-woven bulk kagome). The mechanical strength of the kagome structures is shown relatively stable with the Gaussian types of imperfections.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.78-83
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• 2007

A newly developed cellular metal based on kagome lattice is an ideal candidate for multifunctional materials achieving various optimal properties. Intensive efforts have been devoted to develop efficient techniques for mass production due to its wide potential applications. Since a variety of imperfections would be inevitably included in the realistic fabrication processes, it is highly important to examine the correlation between the imperfections and material strengths. Previous performance tests were mostly done by numerical simulations such as finite element method (FEM), but only for perfect structures without any imperfection. In this paper, we developed an efficient numerical framework using nonlinear random network analysis (RNA) to verify how the statistical imperfections (geometrical and material property) contribute to the performance of general truss structures. The numerical results for kagome truss structures are compared with experimental measurements on 3-layerd WBK (wire-woven bulk kagome). The mechanical strength of the kagome structures is shown relatively stable with the Gaussian types of imperfections.

• Steel and Composite Structures
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• v.5 no.2_3
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• pp.193-202
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• 2005

This paper describes recent developments in composite construction and their effect on codified design procedures in the UK. Areas of particular interest include: rules on shear connection, design of beams with web openings, serviceability limits, such as floor vibrations, and fire safe design. The design of cellular beams with regular circular openings now includes generalized rules for web-post buckling, and for the development of in-plane moment in the web-post for asymmetric sections. Closed solutions for the maximum shear force due to limits on web-post bending or buckling are presented. The fire resistance of cellular beams is also dependent on the temperature of the web-post, and for closely spaced openings. It is necessary to increase the thickness of fire protection to the web. For serviceability design of beams, deflection limits and natural frequency and response factor for vibration are presented. It may be necessary to use stricter limits for certain applications.

• Clinical and Experimental Reproductive Medicine
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• v.41 no.3
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• pp.97-107
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• 2014

The placenta is a temporary fetomaternal organ capable of supporting fetal growth and development during pregnancy. In particular, abnormal development and dysfunction of the placenta due to cha nges in the proliferation, differentiation, cell death, and invasion of trophoblasts induce several gynecological diseases as well as abnormal fetal development. Autophagy is a catalytic process that maintains cellular structures by recycling building blocks derived from damaged microorganelles or proteins resulting from digestion in lysosomes. Additionally, autophagy is necessary to maintain homeostasis during cellular growth, development, and differentiation, and to protect cells from nutritional deficiencies or factors related to metabolism inhibition. Induced autophagy by various environmental factors has a dual role: it facilitates cellular survival in normal conditions, but the cascade of cellular death is accelerated by over-activated autophagy. Therefore, cellular death by autophagy has been known as programmed cell death type II. Autophagy causes or inhibits cellular death via the other mechanism, apoptosis, which is programmed cell death type I. Recently, it has been reported that autophagy increases in placenta-related obstetrical diseases such as preeclampsia and intrauterine growth retardation, although the mechanisms are still unclear. In particular, abnormal autophagic mechanisms prevent trophoblast invasion and inhibit trophoblast functions. Therefore, the objectives of this review are to examine the characteristics and functions of autophagy and to investigate the role of autophagy in the placenta and the trophoblast as a regulator of cell death.

• Journal of Korea Foundry Society
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• v.21 no.1
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• pp.41-47
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• 2001

Computer simulation of the solidification grain structure was applied to the casting process by using CA-DFDM. The Direct Finite Difference Method (DFDM) for temperature field calculation and latent heat treatment was coupled with Cellular Automaton (CA) method for the grain growth. 2-dimensional simulation of the solidification grain structures and calculation of the concentration fields were carried out and the calculated concentration distributions were compared with exact solution. Castings having complex geometries such as turbine blades were applied for 3-dimensional CA-DFDM. Effects of grain selector and mold extraction speed on the solidification grain structures in the turbine blade were examined.

• Journal of Korean Association for Spatial Structures
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• v.7 no.3 s.25
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• pp.119-124
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• 2007

Due to the deficit of section of web, the buckling strength of cellular beam become smaller than that of H-beam. In this thesis, we evaluate the buckling strength of web-post through non-linear F.E.M with opening distance-diameter ratio and opening diameter - web thickness ratio as essential variables. And also analyzes this comparing with the standard indicated in BS5950 Part 1.

• BMB Reports
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• v.48 no.3
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• pp.129-130
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• 2015

Autophagy is a tightly regulated lysosome-mediated catabolic process in eukaryotes that maintains cellular homeostasis. A distinguishable feature of autophagy is the formation of double- membrane structures, autophagosome, which envelopes the intracellular cargoes and finally degrades them by fusion with lysosomes. So far, many structures of Atg proteins working on the autophagosome formation have been reported, however those involved in autophagosome maturation, a fusion with lysosome, are relatively unknown. One of the molecules in autophagosome maturation, TECPR1, has been identified and recently, structural studies on both ATG5-TECPR1 and ATG5-ATG16L1 complexes revealed that TECPR1 and ATG16L1 share the same binding site on ATG5. These results, in combination with supporting biochemical and cellular biological data, provide an insight into a model for swapping ATG5 partners for autophagosome maturation.

• Journal of the korean Society of Automotive Engineers
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• v.1 no.1
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• pp.28-41
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• 1979

Propane-Air premixed combustible gas was ignited by the conventional current break system inside the open combustion chamber under the atmospheric pressure and the room temperature to measure the flame propagating speed and the burning speed, also to elucidate the history of the propagating flame behavior and wall effects to flame shape by using Ion Gap Method and High Speed Schlieren Photography. The results obtained show that the maximum flame propagating speed and maximum burning speed are approximately 292 cm/sec and 36 cm/sec at the mixture ratio 4.6%, respectively. The cellular flame structures can be observable in the rich mixture region, moreover, the cellular structures become finer, with increasing the mixture strength.