• Interaction and multiscale mechanics
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• v.4 no.2
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• pp.165-171
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• 2011

In this study, we proposed a three-dimensional dynamic model under the diffuse interface description for the single crawling cell. From the developed model, we described the clear evolution processes for crawling neutrophil and assessed the reliable quantitative chemotactic property, which confirmed the high possibility of adequate predictions. To establish the system considering of multiple mechanisms such as, diffusion, chemotaxis, and interaction with surface, a diffuse interface model is employed.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.17 no.32
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• pp.63-71
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• 1994

The purpose of this paper is to describe an effective cell scheduling system for flexible manufacturing cells. Based on the FMC characteristics, cell scheduling can be defined as a dynamic modified flow shop working in a real-time system. This paper attempt to find the optimal cell scheduling when minimizing the mean flow time for n-job/m-machine problems in static and dynamic environments. Real-time scheduling in an FMC environment requires rapid computation of the schedule.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.77-77
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• 2003

Gene expression in a cell is regulated by mutual activations or repressions between genes. Identifying the gene regulation network will be one of the most important research topics in the post genomic era. We propose a linear dynamic model of gene regulation for the yeast cell cycle. A small gene network consisting of about 40 genes is reconstructed from the analysis of micro-array gene expression data of yeast S. cerevisiae published by P. Spellman et al. We show that the network construction is consistent with the result of the hierarchical cluster analysis.

• Clinical and Experimental Reproductive Medicine
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• v.46 no.4
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• pp.189-196
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• 2019

Objective: We aimed to evaluate the effects of different oxygen conditions (20% [high O₂], 5% [low O₂] and 5% decreased to 2% [dynamic O₂]) on mouse pre- and peri-implantation development using a novel double-channel gas supply (DCGS) incubator (CNC Biotech Inc.) to alter the oxygen concentration during in vitro culture. Methods: The high-O₂ and low-O₂ groups were cultured from the one-cell to the blastocyst stage under 20% and 5% oxygen concentrations, respectively. In the dynamic-O₂ group, mouse embryos were cultured from the one-cell to the morula stage under 5% O₂ for 3 days, followed by culture under 2% O₂ to the blastocyst stage. To evaluate peri-implantation development, the blastocysts from the three groups were individually transferred to a fibronectin-coated dish and cultured to the outgrowth stage in droplets. Results: The blastocyst formation rate was significantly higher in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. The total cell number was significantly higher in the dynamic-O₂ group than in the low-O₂ and high-O₂ groups. Additionally, the apoptotic index was significantly lower in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. The trophoblast outgrowth rate and spread area were significantly higher in the low-O₂ and dynamic-O₂ groups than in the high-O₂ group. Conclusion: Our results showed that a dynamic oxygen concentration (decreasing from 5% to 2%) had beneficial effects on mouse pre- and peri-implantation development. Optimized, dynamic changing of oxygen concentrations using the novel DCGS incubator could improve the developmental competence of in vitro cultured embryos in a human in vitro fertilization and embryo transfer program.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.7A
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• pp.693-701
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• 2008

In OFDMA (Orthogonal Frequency Division Multiple Access) system that frequency reuse factor is 1, as the same channels in the neighborhood cells creates inter-cell co-channel interference which provides a resource underutilization problem, channel allocation schemes to minimize inter-cell interference have been studied. This paper proposes a new CNIR (Carrier to Noise and Interference Ratio)-based distributed Inter-cell DCA (Dynamic Channel Allocation) algorithm in the OFDMA environment with frequency reuse factor of 1. When a channel allocation is requested, if there is not a free channel in home cell or the available free channels in home cell do not satisfy a required threshold value, the proposed Inter-cell DCA algorithm finds CNIR values of available free channels in the neighborhood cells and then allocates a free channel with maximum CNIR value. Through the simulation results, we find that the proposed scheme decreases both new call block rate and forced termination rate due to new call generation at the same time because it increases channel allocation probability.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2002.04a
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• pp.357-362
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• 2002

Most of battery industries are growing explosively as a core strategy industry for the development of the semi-conductor, the LCD, and the mobile communication device. In this thesis, dynamic characteristics of the steel can labeling machine on the automatic cell assembly line are studied. Dynamic characteristic analysis consists of dynamic behavior analysis and finite element analysis and is necessary for effective design of machines. In the dynamic behavior analysis, the displacement, velocity, applied force and angular velocity of each components are simulated according to each part. In the FEA, stress analysis, mode analysis, and frequency analysis are performed for each part. The results of these simulations are used for the design specification investigation and compensation for optimal design of cell manufacturing line. Therefore, Virtual Engineering of the steel can labeling machine on the automatic cell assembly line systems are modeled and simulated. 3D motion behavior is visualized under real-operating condition on the computer window. Virtual Prototype make it possible to save time by identifying design problems early in development, cut cost by reducing making hardware prototype, and improve quality by quickly optimizing full-system performance. As the first step of CAE which integrates design, dynamic modeling using ADAMS and FEM analysis using NASTRAN are developed.

• 한국신재생에너지학회:학술대회논문집
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• 2011.11a
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• pp.81.1-81.1
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• 2011

High temperature proton exchange membrane fuel cell (HT-PEMFC) has been regarded as a promising clean energy sources. In this study, a quasi-three-dimensional dynamic model of HT-PEMFC has been developed and the local dynamic characteristics are investigated. The model has the geometrical simplification of 2+1D reduction (quasi-3D). The one-dimensional model consists of nine control volumes in cross-sectional direction to solve the energy conservation and the species conservation equations. Then, the one-dimensional model is discretized into 25 local sections along the gas flow direction to account for gas and thermal transport in channels. With this discretization, the local characteristics of HT-PEMFC such as species conservation, temperature, and current density can be captured. In order to study the basic characteristics of HT-PEMFC, it is important to investigate the local dynamic characteristics. Thus, the model is simulated at various operating conditions and the local dynamic characteristics related to them are observed. The model is useful to investigate the distribution of HT-PEMFC characteristics and the physical phenomena in HT-PEMFC.

• Journal of Korean Society of Transportation
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• v.17 no.4
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• pp.71-84
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• 1999

The purpose of this study is to construct a dynamic traffic analysis model using the existing traffic flow theory in order to develope a dynamic traffic assignment technique. In this study the dynamic traffic analysis model was constructed using Daganzo's CELL TRANSMISSION THEORY which was considered more suitable to dynamic traffic assignment than the other traffic flow theories. We developed newly the diverging split module, the cost update module and the link cost function and defined the maximum waiting time decision function that Daganzo haven't defined certainly at his Papers. The output that resulted from the simulation of the dynamic traffic analysis model with test network I and II was shown at some tables and figures, and the analysis of the bottleneck and the HOV lane theory showed realistic outputs. Especially, the result of traffic assignment using the model doesn't show equilibrium status every time slice but showed that the average travel cost of every path maintains similarly in every time slice. It is considered that this model can be used at the highway operation and the analysis of traffic characteristics at a diverging section and the analysis of the HOV lane effect.

• 한국신재생에너지학회:학술대회논문집
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• 2007.11a
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• pp.12-16
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• 2007

A dynamic model of proton exchange membrane fuel cell(PEMFC) system is designed to understand the performance of the PEMFC in residential power generator(RPG) over various balance of plant(BOP) options. In particular, since the performance of PEMFC system should be optimized for given operating ranges, it is necessary to design suitable BDP components which can support the operating ranges. The objective of this study is to develop a dynamic system model for the study of PEMFC performance over various BOP options. Therefore, a dynamic model is composed of a PEMFC stack model, a water management system model, a thermal management system model and a fuel/air supply model and the model is integrated under SIMULINK(R)environment. Basic simulation results will be presented.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.123-128
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• 2014

In this study, we have investigated the flow rate effects of Ag nanoparticle (NP) suspensions on the progress of the cell cycle by using a microfluidic image cytometry (${\mu}FIC$)-based approach. Compared with the conventional "static" exposure conditions, enhancements in G2 phase arrest were observed for the cells under continuously flowing "dynamic" exposure conditions. The "dynamic" exposure conditions, which mimic in vivo systems, induced an enhanced cytotoxicity by accelerating G2 phase arrest and subsequent apoptosis processes. Moreover, we have also shown that the increases in delivered NP dose due to the continuous supply of Ag NPs contributed dominantly to the enhanced cytotoxicity observed under the "dynamic" exposure conditions, while the shear stress caused by these slowly flowing fluids (i.e., flow rates of 6 and $30{\mu}L/h$) had only a minor influence on the observed enhancement in cytotoxicity.