• 제목/요약/키워드: cause of the decline

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Sarcopenia: Nutrition and Related Diseases

  • Du, Yang;No, Jae Kyung
    • 한국조리학회지
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    • 제23권1호
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    • pp.66-78
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    • 2017
  • "Sarcopenia", sarcopenia is an old age syndrome, and used to describe the reduction of skeletal muscle. Initially, it was thought that sarcopenia was only a senile disease characterized by degeneration of muscle tissue. However, its cause is widely regarded as multifactorial, with neurological decline, hormonal changes, inflammatory pathway activation, declines in activity, chronic illness, fatty infiltration, and poor nutrition, all shown to be contributing factors. Skeletal muscle mass can be measured by a variety of methods, currently, the commonly used methods are dual-energy X-ray scanning (DXA), computer tomography (CT), magnetic resonance imaging (MRI), etc. Muscular skeletal disorders can also be assessed by measuring appendicular skeletal muscle (ASM), particularly muscle tissue content. At the same time, sarcopenia refers to skeletal muscle cell denervation, mitochondrial dysfunction, inflammation, hormone synthesis and secretion changes and a series of consequences caused by the above process and is a progressive loss of skeletal muscle syndrome, which can lead to the decrease of muscle strength, physical and functional disorders, and increase the risk of death. Sarcopenia is mainly associated with the aging process, but also related to other causes such as severe malnutrition, neurodegenerative diseases, and disuse and endocrine diseases associated with muscular dystrophy, and it is the comprehensive results of multi-factors, so it is difficult to define that sarcopenia is caused by a specific disease. With the aging problem of the population, the incidence of this disease is increasingly common, and seriously affects the quality of the life of the elderly. This paper reviews the etiology and pathogenesis of myopathy, screening methods and diagnosis, the influence of eating habits, etc, and hopes to provide reference for the diagnosis and treatment of this disease. At present, adequate nutrition and targeted exercise remain the gold standard for the therapy of sarcopenia.

Fluoride in soil and plant

  • Hong, Byeong-Deok;Joo, Ri-Na;Lee, Kyo-Suk;Lee, Dong-Sung;Rhie, Ja-Hyun;Min, Se-won;Song, Seung-Geun;Chung, Doug-Young
    • 농업과학연구
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    • 제43권4호
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    • pp.522-536
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    • 2016
  • Fluorine is unique chemical element which occurs naturally, but is not an essential nutrient for plants. Fluoride toxicity can arise due to excessive fluoride intake from a variety of natural or manmade sources. Fluoride is phytotoxic to most plants. Plants which are sensitive for fluorine exposure even low concentrations of fluorine can cause leave damage and a decline in growth. All vegetation contains some fluoride absorbed from soil and water. The highest levels of F in field-grown vegetables are found up to $40mg\;kg^{-1}$ fresh weight although fluoride is relatively immobile and is not easily leached in soil because most of the fluoride was not readily soluble or exchangeable. Also, high concentrations of fluoride primarily associated with the soil colloid or clay fraction can increase fluoride levels in soil solution, increasing uptake via the plant root. In soils more than 90 percent of the natural fluoride ranging from 20 to $1,000{\mu}g\;g^{-1}$ is insoluble, or tightly bound to soil particles. The excess accumulation of fluorides in vegetation leads to visible leaf injury, damage to fruits, changes in the yield. The amount of fluoride taken up by plants depending on the type of plant, the nature of the soil, and the amount and form of fluoride in the soil should be controlled. Conclusively, fluoride is possible and long-term pollution effects on plant growth through accumulation of the fluoride retained in the soil.

Study of oxidation behavior and tensile properties of candidate superalloys in the air ingress simulation scenario

  • Bin Du;Haoxiang Li;Wei Zheng;Xuedong He;Tao Ma;Huaqiang Yin
    • Nuclear Engineering and Technology
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    • 제55권1호
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    • pp.71-79
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    • 2023
  • Air ingress incidents are major safety accidents in very-high-temperature reactors (VHTRs). Air containing a high volume fraction of oxygen may cause severe oxidation of core components at the VHTR, especially for the significantly thin alloy tube wall in the intermediate heat exchanger (IHE). The research objects of this study are Inconel 617 and Incoloy 800H, two candidate alloys for IHE in VHTR. The air ingress accident scenario is simulated with high-temperature air flow at 950 ℃. A continuous oxide scale was formed on the surfaces of both the alloys after the experiment. Because the oxide scale of Inconel 617 has a loose structure, whereas that of Incoloy 800H is denser, Inconel 617 exhibited significantly more severe internal oxidation than Incoloy 800H. Further, Inconel 617 showed a significant decrease in ultimate tensile strength and plasticity after aging for 200 h, whereas Incoloy 800H maintained its tensile properties satisfactorily. Through control experiment under vacuum, we preliminarily concluded that serious internal oxidation is the primary reason for the decline in the tensile properties of Inconel 617.

Becker형 선천성 근긴장증 1례 (A Case of Becker's Type Congenital Myotonia)

  • 윤성환;하정상;이준
    • Journal of Yeungnam Medical Science
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    • 제16권1호
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    • pp.125-130
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    • 1999
  • 저자들은 최근 25세 여자 환자로 뚜렷한 가족력이 없으면서 3-4세경부터 발생한 근육의 강직현상과 현저한 근비대소견이 있는 환자를 경험하였다. 임상적으로 타진성 근긴장증을 보이고 전기생리적 검사로 새끼손가락 외향근에서의 운동과 반복신경자극에서 복합근육활동전위의 감소를 보였으며, 이두박근의 근생검 소견상 용적이 증가된 근섬유와 중심핵화현상이 관찰되었다. 환자는 mexiletin 경구 투여후 근육의 강직현상이 다소 호전되었다. 이에 문헌고찰과 함께 Becker형 선천성 근긴장증 1례를 보고하는 바이다.

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자동차부품 제조업 근로자의 작업능력과 직무스트레스에 대한 연구 (A Study on the Work Ability and the Job Stress of the Workers in Manufacturing Industry of Automobile Parts)

  • 목연수;이동원;장성록
    • 한국안전학회지
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    • 제28권3호
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    • pp.100-106
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    • 2013
  • According to the Statistics Korea, in 2011, people over the age of 65 years old accounted for 11.8% of Korea's population. This number is expected to rise to 15.0% by 2019, making Korea an "aged society". As age increases, physical ability degrades to the point that the workload must be adjusted limitations. However, workloads are given regardless of workers' ages or abilities. In addition, a decline in work efficiency due to aging also increases the risk of work-related injuries. Furthermore, the cases of stress related diseases along with musculoskeletal disorders(MSDs) rise as main factors of industrial disasters and excessive job stress gives negative influence not only on mental health but also on physical health so that job stress becomes a hot issue as a main cause of work ability falloff and turnover. The purpose of this research is to examine how the sociodemographic characteristics, MSDs symptoms and musculoskeletal workload of workers in the manufacturing industry of automobile parts influence work ability and job stress. As a result of the research, job ability showed significant differences statistically according to age, working year, sex, marital status and musculoskeletal workload and job stress showed significant differences statistically according to age, working year, marital status and musculoskeletal workload. In addition, it showed that as the worker's job ability decreases, job stress increases.

치료 가능한 사망으로 측정한 우리나라 지역 간 건강수준의 격차 (Regional Gaps in Health Status Estimated by Amenable Mortality Rate in Korea)

  • 백세종;김희년;이다호;정형선
    • 보건행정학회지
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    • 제31권1호
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    • pp.100-113
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    • 2021
  • Background: This study aims to figure out the gaps in health status by estimating amenable mortality rate by region, reflecting the characteristics of Korea, and estimating the years of life lost (YLL) per capita by disease. Methods: People who died from amenable diseases between 2008 and 2018 were extracted from the cause of death statistics provided by Statistics Korea. The age-standardized amenable mortality rates were estimated to compare the health status of 229 regions. YLL per capita was calculated to compute the burden of diseases caused by treatable deaths by region. The YLL per capita by region was calculated to identify the burden of disease caused by amenable deaths. Results: First, while the annual amenable mortality rate in Korea is on a steady decline, but there is still a considerable gap between urban and rural areas when comparing the mortality rates of 229 areas. Second, YLL per capita due to the amenable deaths is approximately 14 person-years during the analysis period (2008-2018). Conclusion: Although the health status of Koreans has continuously improved, there is still a gap in health status region by region in terms of amenable mortality rates. Amenable death accounts for a loss of life equivalent to 14 person-years per year. Since the amenable mortality rate is an indicator that can measure the performance of the health care system, efforts at each local area are required to lower it.

납고무받침의 노화가 교량의 내진성능에 미치는 영향 (Influence of Aging of Lead Rubber Bearing on Seismic Performance of Bridges)

  • 박성규;오주
    • 대한토목학회논문집
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    • 제32권2A호
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    • pp.109-116
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    • 2012
  • 지진격리장치로서 납고무받침의 동적 특성은 주재료인 고무재료의 동적거동과 비선형 성질에 의존하고 있다. 역학적이나 환경적인 영향으로 인해 고무재료에 노화가 진행되고 결국에는 손상이 불가피하게 발생하게 된다. 고무재료의 노화의 주원인은 높은 온도에서 반응열로 인한 산화반응으로 알려져다. 이에 따라 납고무받침의 가속 열 노화실험을 수행하여 열 노화 전 후에 대해 받침의 특성값을 상호 비교하였다. 실험 결과 열 노화 현상은 전단강성과 에너지 감쇠 그리고 등가감소계수에 영향이 있음을 알 수 있었다. 또한 열 노화에 의한 동적특성의 저하를 실제 교량에 적용하여 납고무받침의 열 노화가 교량의 교각의 내진성능에 미치는 영향을 수치해석을 통해 비교분석하였다. 해석결과 납고무받침에 대하여 열 노화에 따른 기본 특성변화가 교량의 내진성능에 미치는 영향은 크지 않음을 알 수 있었다.

유통채널 소비 분석: 대형마트 소비 감소를 중심으로 (An Analysis of Retail Channel Consumption: Focusing on the Reduced Consumption at Hypermarkets)

  • 박진영;김형중
    • 디지털콘텐츠학회 논문지
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    • 제18권7호
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    • pp.1357-1366
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    • 2017
  • 스마트폰 보급 확대, 1인 가구 증가 등의 국내 소비 환경 변화 속에서 기존 유통 시장의 주축이었던 대형마트는 매출이 감소하면서 최근 3년 동안 마이너스 성장률을 기록하고 있지만 대형마트 매출 관련된 연구는 주로 영업규제에 따른 효과 분석 위주였으며 다른 유통채널과의 영향관계 분석이나 소비 이동 사유 조사는 부족한 실정이다. 본 연구는 카드사 매출 빅데이터를 활용하여 대형마트 성장률 감소를 소비자의 인구통계학적 변수 및 소비시점 등에 따라 분석하고 로지스틱 회귀 분석을 통하여 대형마트 소비 감소와 다른 유통채널 매출비중 변화와의 관계 등을 실증적으로 규명하였다. 또한 실제 카드소비 데이터 기반 대형마트 소비 감소 소비자를 대상으로 설문조사를 수행하여 다른 유통채널 선택 사유가 무엇인지 밝혔다. 이는 유통채널 소비 변화에 대한 정량적 분석 결과와 정성적인 사유 조사 결과를 융합하여 소비에 대한 입체적인 조망을 하였다는 점에서 의의가 있다.

Li Ion Diffusivity and Rate Performance of the LiFePO4 Modified by Cr Doping

  • Park, Chang-Kyoo;Park, Sung-Bin;Shin, Ho-Chul;Cho, Won-Il;Jang, Ho
    • Bulletin of the Korean Chemical Society
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    • 제32권1호
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    • pp.191-195
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    • 2011
  • This study reports the root cause of the improved rate performance of $LiFePO_4$ after Cr doping. By measuring the chemical diffusion coefficient of lithium ($D_{Li}$) using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), the correlation between the electrochemical performance of $LiFePO_4$ and Li diffusion is acquired. The diffusion constants for $LiFePO_4$/C and $LiFe_{0.97}Cr_{0.03}PO_4$/C measured from CV are $2.48{\times}10^{-15}$ and $4.02{\times}10^{-15}cm^2s^{-1}$, respectively, indicating significant increases in diffusivity after the modification. The difference in diffusivity is also confirmed by EIS and the $D_{Li}$ values obtained as a function of the lithium content in the cathode. These results suggest that Cr doping facilitates Li ion diffusion during the charge-discharge cycles. The low diffusivity of the $LiFePO_4$/C leads to the considerable capacity decline at high discharge rates, while high diffusivity of the $LiFe_{0.97}Cr_{0.03}PO_4$/C maintains the initial capacity, even at high C-rates.

시스템 개선을 통한 핵의학 검사실의 공간 선량률 감소방안 (Solution to Decrease Spatial Dose Rate in Laboratory of Nuclear Medicine through System Improvement)

  • 문재승;신민용;안성철;유문곤;김수근
    • 한국의료질향상학회지
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    • 제20권1호
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    • pp.60-73
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    • 2014
  • Objectives: This study aims at decreasing spatial dose rate through work improvement whilst spatial dose rate is the cause of increasing personal exposure dose which occurs in the process of handling radioisotope. Methods: From February 2013 until July 2013, divided into "before" and "after" the improvement, spatial dose rate in laboratory of nuclear medicine was measured in gamma image room, PET/CT-1 image room, and PET/CT-2 image room as its locations. The measurement time was 08:00, 12:00 and 17:00, and SPSS 21.0 USA was opted for its statistical analysis. Result: The spatial dose rate at distribution worktable, injection table, the entrance to the distribution room, and radioisotope storage box, which had showed high spatial dose rate, decreased by more than 43.7% a monthly average. The distribution worktable, that had showed the highest spatial dose rate in PET/CT-1 image room, dropped the rate to 42.3% as of July. The injection table and distribution worktable in the PET/CT-2 image room also showed the decline of spatial dose rate to 89% and 64.4%, respectively. Conclusion: By improving distribution process and introducing proper radiation shielding material, we were able to drop the spatial dose rate substantially at distribution worktable, injection table, and nuclide storage box. However, taking into account of steadily increasing amount of radioisotope used, strengthening radiation related regulations, and safe utilization of radioisotope, the process of system improvement needs to be maintained through continuous monitoring.