• Title/Summary/Keyword: case control studies

Search Result 1,587, Processing Time 0.031 seconds

Analysis on Types of Errors in Learning about Control Structures of Programming using Flowchart (순서도를 활용한 프로그래밍 제어 구조 학습에 나타난 오류 유형 분석)

  • Choe, Hyunjong
    • The Journal of Korean Association of Computer Education
    • /
    • v.19 no.1
    • /
    • pp.101-109
    • /
    • 2016
  • Designing algorithms is a very important learning process in computational thinking education because it requires learner's logical and procedural thinking. But the case studies that have topics of algorithms learning and students' types of errors in learning algorithms are not enough. So the purpose of this study is to analyze students' errors that discovered in the process of learning three control structures of programming using flowchart and provide types of errors in designing algorithms. Results about tests of three types of control structures in university student's algorithms learning class showed different cases of types of errors; types of sequential control error are not presented in the class, types of conditional control error are presented in the case of setting the conditions of nested conditional control, and types of iterative control are showed in the many cases of iterative conditions, statements of single and nested iterative control structure. The results of study will be a good case study about teaching designing algorithms of computational thinking education in elementary, secondary school and university.

A Review of Acupuncture Treatment for Infertility

  • Chun, Hea sun;Song, Ho-Sueb
    • Journal of Acupuncture Research
    • /
    • v.38 no.4
    • /
    • pp.257-264
    • /
    • 2021
  • The purpose of this study was to analyze acupuncture treatment methods and acupoint used to treat infertility in the last decade. The data were retrieved from 2010.1 to 2021.8. using national and international electronic databases (PubMed, EMBASE, OASIS, NDSL, and KISS). "Infertility," "sterility," "acupuncture," "electroacupuncture," "bloodletting," "pharmacopuncture," were used as search terms. All studies were mainly concerned with acupuncture treatment of infertility, but the studies which were not related included; (1) infertility or acupuncture treatment; (2) animal studies; (3) review/meta/protocol or clinical study; comparative studies and case reports which were excluded from this review. Only clinical trials for acupuncture treatment of infertility were included in this review (n = 18). For infertility treatment studies using acupuncture, polycystic ovarian syndrome was the main cause of infertility, the most common acupoint used was CV4, CV3, CV6, SP6, BL23, and the treatment effect significantly improved in the group receiving acupuncture treatment compared with the control group, or the group taking Western medicine alone. In some studies, the group using acupuncture treatment did not show side effects. Acupuncture is an effective treatment for infertility.

Logistic Regression for Retrospective Studies

  • Shin, Mi-Young
    • Journal of Korean Society for Quality Management
    • /
    • v.22 no.4
    • /
    • pp.111-119
    • /
    • 1994
  • We consider logistic models based on retrospective, case-control data with stratified samples and study the Weighted Exogeneous Sampling Maximum Likelihood (WESMU) We develop a consistent estimator of the asymptotic covariance matrix of the WESML estimator.

  • PDF

High Intensity Laser for Laser Acupuncture Application (침구치료에 사용되는 고출력 레이저에 대한 고찰)

  • Yang, Chang-Sop;Sun, Seung-Ho;Jang, In-Soo
    • Korean Journal of Acupuncture
    • /
    • v.28 no.3
    • /
    • pp.1-12
    • /
    • 2011
  • Objectives : The purpose of this study is to review laser acupuncture studies to find possibility for applying high intensity laser to acupuncture and moxibustion treatment. Methods : Searching papers was performed using search engines of five electronic databases, including Pubmed, Thomson ISI, EMBASE, Sciencedirect, and EBSCO, from inception to May 2011 without language limitation. Inclusion criteria were clinical studies with human, randomized controlled trials (RCTs), case-control studies, and case reports. Selecting papers was performed with titles and abstracts in first step, scrutinize full text in second step, and then the extrated data was analyzed by two authors independently. The methodological quality for RCTs was evaluated using Jadad's scale. Results : Total 8 papers, (3 RCTs, 5 controlld studies, and 1 case reports), were finally selected. The study dealt with surgical laser, argon and $CO_2$ laser was one for each, with GaAs laser was two, and with new semiconductor laser, GaN, were four. The output range was from 110 mW to 15 W. The study diseases were alcohol addiction, knee osteoarthritis, bronchopneumonia and asthma for children, and circulation. All studies reported positive effect. The methodological quality in all RCTs was low because of below 3 points and all studies had few subject numbers. Conclusions : We suggest that high intensity laser can be applied to acupuncture and moxibustion. Further rigorous and well-designed study will be needed for various disease. The oriental medical society needs to take active measures to study and clinical application of acupuncture and moxibustion treatment with high intensity laser.

A Trend Analysis of Clinical Studies of Medical Gigong (formerly Journal of the Korean Academy of Medical Gi-Gong) (의료기공(구 대한의료기공학회지)에 실린 임상논문의 경향 분석)

  • Na, Sam Sik;Jeong, Jae Hun;Ahn, Hun Mo
    • Journal of Korean Medical Ki-Gong Academy
    • /
    • v.20 no.1
    • /
    • pp.68-84
    • /
    • 2020
  • Objective : The purpose of this study is to suggest the evidence of traditional Korean medicine by analyzing the clinical research trends of the Korean Academy of Medical Gi-Gong and to use it as reference data for future clinical studies. Methods : The clinical studies published in the Journal of the Korean Academy of Medical Gi-Gong from 2011 to 2019 were reviewed and the study design, yearly trends, patient's disease, therapeutic intervention, and outcome measure were analyzed. Results : Of the 24 clinical studies, there are 13 Case Reports, 9 Case Series Researches, and 2 Case-Control Studies. In terms of disease group, Musculoskeletal Diseases and female Diseases were the most common, followed by neurological Diseases, dermatological Diseases, and rare Diseases. In terms of treatment methods, acupuncture, herbal medicine, and Sugi therapy were mainly used. And cupping, thermotherapy, and Korean medical exercise therapy were used as a supplement. As an evaluation tool, clinical symptom change was the most common, followed by DITI, VAS, survey, and X-ray. In most reports, Korean medical treatment has been effective in treating diseases. Conclusions : More clinical studies including controlled clinical trials should be conducted to provide a basis for verifying the effectiveness of Korean medicine.

Orungsan(Goreisan) Application in Neurosurgical Field: Review of the Studies Reported in the 20th Annual Meeting of Kampo Medicine Association of the Japan Neurosurgical Society (뇌혈관질환에 대한 오령산(五苓散) 치료의 일본 유용성 - 2011년 제20회 일본뇌신경외과한방의학회 학술대회 발표논문을 중심으로-)

  • Jang, In-soo;Kwon, Seung-won;Kim, Kying-wook
    • The Journal of the Society of Stroke on Korean Medicine
    • /
    • v.12 no.1
    • /
    • pp.1-7
    • /
    • 2011
  • Objectives : The purpose is to discuss the clinical applications of Orungsan(Goreisan: 五苓散) as an alternative management for increased intracranial pressure in the field of neurosurgery in Japan. Methods and Results : Attention has focused on Kampo medicine(traditional Japanese medicine) for some cerebral disease including chronic subdural hematoma(CSDH) and cerebral infarction in Japan. Orungsan and one of its classes, Sirungtang(Saireto: 柴苓湯) are well known their effects on brain edema. After some studies of Orungsan has the anti-edemic effects by the inhibition of aquaporin, this herbal medicine has been used widely in the neurosurgery field in Japan. It is high time to think about where we are and we go ahead for the progress and the integration in medicine. We have reviewed the studies using Orungsan or Sirungtang, that was reported at the 20th annual meeting of 'the Japan society for Kampo medicine and neurological surgery' was held on November 5, 2011 in Tokyo. Fifteen studies related with Orungsan or Sirungtang were reported among all 32 studies at the meeting. Orungsan in ten, and Sirungtang in five among 14 studies contained specific clinical case. In the aspects of disease, thirteen papers were related with SDH, including CSDH(11), SSDH(1), aneurism clipping for SDH prevention(1), and one was acute cerebral infarction and one was multiple metastatic brain tumor. In the report style, case control study was 7(mostly retrospective), and the case report was 8. Conclusions : Orungsan may be plausible to be an alternative method to reduce brain edema after SDH and other brain injury in the field of neurosurgery.

  • PDF

G894T and 4a/b Polymorphisms of NOS3 Gene are Not Associated with Cancer Risk: a Meta-analysis

  • Haque, Shafiul;Mandal, Raju K;Akhter, Naseem;Panda, Aditya K;Hussain, Arif;Khan, Saif;Lohani, Mohtashim
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.7
    • /
    • pp.2929-2937
    • /
    • 2015
  • Endothelial nitric oxide synthase (eNOS or NOS3) produces nitric oxide and genetic polymorphisms of NOS3 gene play significant roles in various processes of carcinogenesis. The results from published studies on the association between NOS3 G894T and NOS3 intron 4 (4a/b) polymorphisms and cancer risk are conflicting and inconclusive. However, i n order to assess this relationship more precisely, a meta-analysis was performed with PubMed (Medline), EMBASE and Google web searches until February 2014 to select all published case-control and cohort studies. Genotype distribution data were collected to calculate the pooled odd ratios (ORs) and 95% confidence intervals (CIs) to evaluate the strength of association. A total of 10,546 cancer cases and 10,550 controls were included from twenty four case-control studies for the NOS3 G894T polymorphism. The results indicated no significant association with cancer risk as observed in allelic (T vs G: OR=1.024, 95%CI=0.954 to 1.099, p=0.508), homozygous (TT vs GG: OR=1.137, 95%CI=0.944 to 1.370, p=0.176), heterozygous (GT vs GG: OR=0.993, 95%CI=0.932 to 1.059, p=0.835), recessive (TT vs GG+GT: OR=1.100, 95%CI=0.936 to 1.293, p=0.249) and dominant (TT+GT vs GG: OR=1.012, 95%CI=0.927 to 1.105, p=0.789) genetic models. Similarly, a total of 3,449 cancer cases and 3,691 controls were recruited from fourteen case-control studies for NOS3 4a/b polymorphism. Pooled results indicated no significant association under allelic (A vs B: OR=0.981, 95%CI=0.725 to 1.329, p=0.902), homozygous (AA vs BB: OR=1.166, 95%CI=0.524 to 2.593, p=0.707), heterozygous (BA vs BB: OR=1.129, 95%CI=0.896 to 1.422, p=0.305), dominant (AA+BA vs BB: OR=1.046, 95%CI=0.779 to 1.405, p=0.763) and recessive (AA vs BB+BA: OR=1.196, 95%CI=0.587 to 2.439, p=0.622) genetic contrast models. This meta-analysis suggests that G894T and 4a/b polymorphisms of NOS3 gene are not associated with increased or decreased risk of overall cancer.

MLH1 Polymorphisms and Cancer risk: a Meta-analysis Based on 33 Case-control Studies

  • Xu, Jia-Li;Yin, Zhi-Qiang;Huang, Ming-De;Wang, Xie-Feng;Gao, Wen;Liu, Ling-Xiang;Wang, Rong-Sheng;Huang, Pu-Wen;Yin, Yong-Mei;Liu, Ping;Shu, Yong-Qian
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.3
    • /
    • pp.901-907
    • /
    • 2012
  • Objective: Cumulative evidence suggests that MLH1, the key component in the mismatch pathway, plays an important role in human cancers. Two potential functional polymorphisms (-93G>A and I219V) of MLH1 have been implicated in cancer risk. The aim of this meta-analysis was to summarize the evidence for associations. Methods: Eligible studies were identified by searching the electronic literature PubMed, ScienceDirect and Embase databases for relevant reports and bibliographies. Studies were included if of case-control design investigating MLH1 polymorphisms (-93G>A and I219V) and cancer risk with sufficient raw data for analysis. Odds ratios (OR) and 95% confidence intervals (95% CI) were used to evaluate the strength of associations. Results: Our meta-analysis from 33 published case-control studies showed the variant A allele of -93G>A polymorphism to be associated with increased risk in all genetic models (AA vs. GG: OR = 1.22, 95% CI: 1.03-1.44), especially among non-Asians (AA vs. GG: OR = 1.28, 95% CI: 1.04-1.58). For the I219V polymorphism, however, there was no main effect associated with overall cancer risk in any genetic model. Conclusions: The meta-analysis suggested that the MLH1 -93G>A polymorphism may be a biomarker of cancer susceptibility. Large sample association studies and assessment of gene-to-gene as well as gene-to-environment interactions are required to confirm these findings.

Active Vibration Control of a Structure with Output Feedback Based on Simultaneous Optimization Design Method

  • Kim, Young-Bok
    • Journal of Mechanical Science and Technology
    • /
    • v.14 no.1
    • /
    • pp.57-64
    • /
    • 2000
  • Recent advances in the field of control theory have enabled us to design active vibration control systems for various structures. In many studies, the controller used to suppress vibration has been synthesized for the given mathematical model of structure. In these cases, the designer has not been able to utilize the degree of freedom to adjust the structural parameters of the control object. To overcome this problem, so called 'Structure/Control Simultaneous Optimization Method' is used. In this context of view, this paper is concerned with the active vibration control of bridge towers, platforms and ocean vehicles etc. Simultaneous design method is used to achieve optimal system performance. Here, a general framework for the simultaneous design problem of output feedback case is introduced based on LMI (Linear Matrix Inequality). The simulation results show that the proposed design method achieves desirable control performance.

  • PDF