• Journal of Information Technology Applications and Management
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• 제14권4호
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• pp.97-120
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• 2007

Development of information technology and Internet brought big changes in information society. Quantity of information increased rapidly and various types of information were presented through diverse channels. This change brought an impact in electronic commerce environment. A large number of products are transacted in online market. And various search functions and product information are presented for supporting customer's decision making. This study examined the effect of external information on purchase decision-making in electronic commerce environment. An experiment was conducted to see the customer product review, unit sales, etc. on purchase decision-making process in online shopping mall based electronic commerce. As a result of study, external information referring to number of purchasing, positive product review, and reliability of information has a positive effect on purchase-decision. The significance of the study can be found in that it defined 1) external information has an effect on decision-making, 2) positiveness and reliability of product information showed that they have an influence on customer, and 3) when self opinion and other person's opinion are different, one is not satisfied with decision making process. The results of the study can be of practical use in the design and implementation of online shopping mall in electronic commerce.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.2418-2423
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• 2005

Hard Disk Drive (HDD) test system is the equipment for the final test of HDD product by iterative read/write/seek test. This paper proposes an expert system for the fault diagnosis of HDD test systems. The purposed expert system is composed with two cascade inference, fuzzy logic and conventional binary logic. The fuzzy logic determines the possibility of the system fault using the test history data, then, the binary logic inferences the fault location of the test system. The proposed expert system is tested in SAMSUNG HDD product line, KUMI, KOREA, and shows satisfactory results.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.2424-2429
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• 2005

Hard Disk Drive (HDD) test system is the equipment for the final test of HDD product by iterative read/write/seek test. This paper proposes an expert system for the fault diagnosis of HDD test systems. The purposed expert system is composed with two cascade inference, fuzzy logic and conventional binary logic. The fuzzy logic determines the possibility of the system fault using the test history data, then, the binary logic inferences the fault location of the test system. The proposed expert system is tested in SAMSUNG HDD product line, KUMI, KOREA, and shows satisfactory results.

• 청정기술
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• 제1권1호
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• pp.34-46
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• 1995

Clean Technology goes beyond Clean-UP (or "End of PiPe) Technologies to include Pollution prevention, waste minimisation, and cleaner production. However, the concept of Clean Technology goes deeper than changes in technology, to ways in which human needs can be satisfied sustainably. In other words, Clean Technology, concentrates on delivering a human benefit rather than making a product. Introducing cleaner technology may therefore involve new commercial relationships as well as new technological practices. In some economic sectors, this involves leasing or providing a service rather than selling a product. Life Cycle Assessment (LCA) is an important tool in Clean Technology. LCA involves determining all the resources used and all the wastes and emissions produced in providing the human benefit. Use of LCA ensures that improved environmental performance in one part of the Life Cycle is not achieved merely at the expense of more environmental damage elsewhere. Going beyond LCA, the concepts of Life Cycle Design and "metabolised" use of materials are approaches to obtain maximum benefit from materials as they pass through the human economy. "Closed-loop" use can be a component of clean technology. Looking beyond simple re-use and recycling, a material may pass through a "cascade of uses". typically a series of applications with progressively lower performance specifications. Closed-loop use necessarily involves a change in commercial practice, because the material or product must be recovered after use.

• BMB Reports
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• 제47권7호
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• pp.376-381
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• 2014

Enzymatic oxidation of pyrogallol was efficiently transformed to an oxidative product, purpurogallin (PPG). Here, the anticoagulant activities of PPG were examined by monitoring activated partial thromboplastin time (aPTT), prothrombin time (PT), and the activities of thrombin and activated factor X (FXa). And, the effects of PPG on expression of plasminogen activator inhibitor type 1 (PAI-1) and tissue-type plasminogen activator (t-PA) were evaluated in tumor necrosis factor (TNF)-${\alpha}$ activated human umbilical vein endothelial cells (HUVECs). Treatment with PPG resulted in prolonged aPTT and PT and inhibition of the activities of thrombin and FXa, as well as inhibited production of thrombin and FXa in HUVECs. In addition, PPG inhibited thrombin-catalyzed fibrin polymerization and platelet aggregation. PPG also elicited anticoagulant effects in mice. In addition, treatment with PPG resulted in significant reduction of the PAI-1 to t-PA ratio. Collectively, PPG possesses antithrombotic activities and offers a basis for development of a novel anticoagulant.

• 대한전기학회논문지:시스템및제어부문D
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• 제53권6호
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• pp.457-464
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• 2004

Hard Disk Drive (HDD) test system is an equipment for the final test of HDD product by iterative read/write/seek test. This paper proposes an expert system for the fault diagnosis of HDD test systems. The purposed expert system is composed with two cascade inference, fuzzy logic and conventional binary logic. The fuzzy logic determines the possibility of the system fault using the test history data, then, the binary logic inferences the fault location of the test system. The proposed expert system is tested in SAMSUNG HDD production line, KUMI, KOREA, and shows satisfactory results.

• 한국약용작물학회지
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• 제17권5호
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• pp.341-345
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• 2009

Cerebral ischemia results from a transient or permanent reduction in cerebral blood flow that decreases oxygen and glucose supply. When the cellular oxygen supply is reduced to critical level, damage to cells and induction of cell death are occurred by excitotoxicity, oxidative stress and inflammation. Ischemia remains one of the leading causes of death, but there is no effective treatment that might protect neurons gainst ischemia by interrupting the cascade of cell death. In this study, human neuroblastoma SH-SY5Y cells are exposed to oxygen and glucose deprivation (OGD) followed by reoxgenation. OGD can mimic the acute restriction of metabolite and oxygen supply caused by ischemia and is widely used as a model of ischemic conditions. SH-SY5Y cells are treated samples at the commencement of OGD to achieve different final concentrations, and cell viabilities were quantified using the measurement of flow cytometry analysis. Of those tested, the extracts of Polygala tenuifolia (roots), Dictamnus dasycarpus (barks), Polygala tenuifolia (roots), Eucommia ulmoides (branches), Eucommia ulmoides (barks), Poria cocos (whole), Sophora flavescens (roots) showed neuroprotective effects, with $EC_{50}$ values of $4.5{\pm}0.6$, $7.9{\pm}1.5$, $10.5{\pm}0.7$, $18.4{\pm}1.9$, $19.6{\pm}0.3$, $21.6{\pm}1.9$, and $30.7{\pm}3.9{\mu}g/m{\ell}$, respectively.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.15-23
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• 2003

Interest in the regulation of body weight and the pathological physiology of obesity has been rekindled by the cloning of the obese(ob) gene and identification of its product, leptin, in 1994. The first publication appeared in Nature and is a milestone of obesity research. The remarkable metabolic effects of leptin in rodents are: a) inhibition of food intake, b) stimulation of energy expenditure, and c) reversal of obesity. These effects, though mostly desirable, have not been fully demonstrated in humans. The central action of leptin in the regulation of body weight includes two pathways in rodents: a) When the body weight increasing, more leptin is secreted from adipose tissue, which acts on hypothalamus, probably through a POMC or MSH pathway via M4 receptor, initiates a series of response to obesity, i.e. sympathetic tone increased, energy expenditure enhanced and food intake reduced. b) When body weight reduced, leptin concentration decreased with the shrinkage of fat mass, which may also act on the hypothalamus, probably through a NPY-Y5 receptor pathway. Then a cascade of response to hungry was induced, i.e. increase of parasympathetic tone and food intake, decrease of energy expenditure and body temperature, as well as shut-down of the reproductive function.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1998년도 Proceedings of UNESCO-internetwork Cooperative Regional Seminar and Workshop on Bioassay Guided Isolation of Bioactive Substances from Natural Products and Microbial Products
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• pp.145-145
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• 1998

In the present study, we have demonstrated that taurine could stimulate the production of nitric oxide and the activity of ERK2 (extracellular signal regulated protein kinase or pp42 MAP kinase). Nitric oxide(NO), the product of inducible nitric oxide synthase(iNOS), is known to be implicated in the metabolism of bone. ERK cascade plays a key role in the gene expression of iNOS in osteoblastic cell. We investigated whether taurine (l-20mM) could stimulate ERK2 activity, nitric oxide production, and inducible nitric oxide synthase in osteoblast-like UMR-106 cells. Nitric oxide was measured spectophotometrically as nitrite and the activation of ERK2 and iNOS was studied using Western 145 blot analysis. Taurine increased the production of nitric oxide in a dose-dependent manner and the effect was reached to a maximum at 10 mM. The activation of iNOS were consistent with NO levels. The tyrosine phosphorylation of ERK2 was increased by taurine in a time-dependent manner. The these result suggest that taurine might stimulate the production of nitric oxide in osteoblast-like cells by the activation of ERK2 and could regulate the metabolism of bone via nitric oxide.

• Natural Product Sciences
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• 제16권2호
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• pp.88-92
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• 2010

We verified that the apoptosis activities were examined by DNA fragmentation, flow cytometric analysis with annexin V staining, activation of caspase-3, and cytochrome c release. In the result, $\alpha$- and $\beta$-eudesmol induced DNA fragmentation in HL-60 cells at a concentration of $80\;{\mu}M$, respectively. Additionally, pro-apoptotic cells sorted by flow cytometry analysis were detected in HL-60 cells to 31.77 and 29.67% with $\acute{a}$- and $\beta$-eudesmol of $80\;{\mu}M$. Thus, both $\alpha$- and $\beta$-eudesmol exerted caspase-3 activation and cytochrome c release at $80\;{\mu}M$ in HL-60 cells. These results are firstly reported that the sesquiterpenes, $\alpha$- and $\beta$-eudesmol are apoptosis inducers through mitochondria-dependent caspase cascade in HL-60 cells.