• Title/Summary/Keyword: carbonate region

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The Functional Behaviors of Cosurfactant in Design of Self-nanoemulsifying Drug Delivery Systems

  • Yang, Su-Geun;Shin, Hee-Jong
    • Journal of Pharmaceutical Investigation
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    • v.40 no.5
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    • pp.263-267
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    • 2010
  • Nanoemulsions have been widely investigated for many years because of their attractive and unique characteristics. Nanoemulsions are composed of oil, surfactant, co-surfactant and water. Especially, cosurfactant plays a critical role in formation of nanoemulsions. In pharmaceutical area, a pre-concentrate form of nanoemulsions which is known as self-nanoemulsifying drug delivery systems (SNEDDS) was available for some water-insoluble drugs. In this study, we investigated the functional behaviors of cosurfactant in design of SNEDDS and nanoemulsions. Cremophor RH 40$^{(R)}$, Propylene carbonate and medium chain triglyceride were selected for surfactant, cosurfactant and oil, respectively. Cyclosporine was employed as a drug. Phase diagrams showed the area of isotropic o/w region which forms o/w nanoemulsions was not significantly affected by the compositional ratio of cosurfactant. But, drug solubilization capacity, droplet size of nanoemulsions and drug release rate were greatly affected by the cosurfactant.

A Case of Cholecystotomy in a Dog with Cholelithiasis (개에서 담석제거를 위한 담낭절개술의 일례)

  • 구자민;황재민;김현희;이원익;손우진
    • Journal of Veterinary Clinics
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    • v.18 no.4
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    • pp.455-458
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    • 2001
  • A twelve-month old female, shih-tzu, was presented to diagnose a hind limb ataxia to the Animal Teaching Hospital, Gyeongsang National University. Even though a variety of physical and neurological examination was performed, the cause of the ataxia was not understood. In serum analysis, an elevated levels of ALT, $\gamma$-GTP and LDH were found. A gallstone was subsequently observed at the right 9 and 10th intercostal region on ultrasonography and radiography. Cholelithiasis was diagnosed, and then cholecystotomy was undertaken. No complications were occurred after the operation. The gallstone removed by cholecystotomy was composed of calcium, carbonate and oxalate, identified by a black pigment gallstone.

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Heavy Metal Distribution in Soils from the Maehyang-ri Inland Shooting Range Area (매향리 내륙 사격장 토양의 중금속 오염 분포)

  • Lee, Jun-Ho;Park, Kap-Song
    • Journal of Korean Society on Water Environment
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    • v.24 no.4
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    • pp.407-414
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    • 2008
  • This study was conducted to evaluate the heavy metal contamination in the soils of Maehyang-ri inland shooting range area. The texture of the Maehyang-ri inland shooting range soil was sandy. Extraction of heavy metals reached quasi-equilibrium within 6 hours using shaking with 0.1 N HCl. 95% and 94% of extraction efficiency was observed for Cu and Pb in the Maehyang-ri shooting range soils, respectively. And Cu and Pb contamination of level of the T-1 region soil was $114.4{\pm}5.7mg/kg$ and $362.3{\pm}20.5mg/kg$. This may be due to the effects of mineralogical factor, soil particle size and un-residual fractions such as exchangeable, carbonate, Fe-Mn oxide and organic+sulfide.

Efficiency and Lifetime Improvement of Organic Light- Emitting Diodes with a Use of Lithium-Carbonate- Incorportated Cathode Structure

  • Mok, Rang-Kyun;Kim, Tae-Wan
    • Transactions on Electrical and Electronic Materials
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    • v.13 no.2
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    • pp.60-63
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    • 2012
  • Enhancement of efficiency and luminance of organic light-emitting diodes was investigated by the introduction of a lithium carbonate ($Li_2CO_3$) electron-injection layer. Electron-injection layer is used in organic light-emitting diodes to inject electrons efficiently between a cathode and an organic layer. A device structure of ITO/TPD (40 nm)/$Alq_3$ (60 nm)/$Li_2CO_3$ (x nm)/Al (100 nm) was manufactured by thermal evaporation, where the thickness of $Li_2CO_3$ layer was varied from 0 to 3.3 nm. Current density-luminance-voltage characteristics of the device were measured and analyzed. When the thickness of $Li_2CO_3$ layer is 0.7 nm, the current efficiency and luminance of the device at 8.0 V are improved by a factor of about 18 and 3,000 compared to the ones without the $Li_2CO_3$ layer, respectively. The enhancement of efficiency and luminance of the device with an insertion of $Li_2CO_3$ electron-injection layer is thought to be due to the lowering of an electron barrier height at the interface region between the cathode and the emissive layer. This is judged from an analysis of current density-voltage characteristics with a Fowler-Nordheim tunneling conduction mechanism model. In a study of lifetime of the device that depends on the thickness of $Li_2CO_3$ layer, the optimum thickness of $Li_2CO_3$ layer was obtained to be 1.1 nm. It is thought that an improvement in the lifetime is due to the prevention of moisture and oxygen by $Li_2CO_3$ layer. Thus, from the efficiency and lifetime of the device, we have obtained the optimum thickness of $Li_2CO_3$ layer to be about 1.0 nm.

Influence of Ni Thin Film Position on the Opto-electrical Properties of GZO Films (Ni 박막 위치에 따른 GZO 투명전도막의 전기광학적 물성 변화)

  • Mun, Hyun Joo;Jeon, Jae-Hyun;Gong, Tae-Kyung;Seo, Ki-Woong;Oh, Jeong Hyun;Kim, Sun-Kyung;Choi, Dong-Hyuk;Son, Dong-Il;Kim, Daeil
    • Journal of the Korean Society for Heat Treatment
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    • v.28 no.3
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    • pp.121-125
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    • 2015
  • GZO single layer, Ni buffered GZO(GZO/Ni), Ni intermediated GZO (GZO/Ni/GZO) and Ni capped GZO (Ni/GZO) films were prepared on poly-carbonate (PC) substrates by RF and DC magnetron sputtering without intentional substrate heating and then the influence of the Ni (2 nm thick) thin film on the optical, electrical and structural properties of GZO films were investigated. As deposited GZO single layer films show the optical transmittance of 81.3% in the visible wavelength region and a resistivity of $1.0{\times}10^{-2}{\Omega}cm$, while GZO/Ni/GZO trilayer films show a lower resistivity of $6.4{\times}10^{-4}{\Omega}cm$ and an optical transmittance of 74.5% in this study. Based on the figure of merit, it can be concluded that the intermediated Ni thin film effectively enhances the opto-electrical performance of GZO films for use as transparent conducting oxides in flexible display applications.

Downward particle flux in the eastern Bransfield Strait, Antarctica

  • Kim, Dongseon;Kim, Dong-Yup;Jeonghee Shim;Kang, Young-Chul;Kim, Taerim
    • Journal of the korean society of oceanography
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    • v.38 no.1
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    • pp.1-10
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    • 2003
  • A time-series sediment trap was deployed at a depth of 1034 m in the eastern Bransfield Strait from December 25, 1998 to December 24, 1999. Particle fluxes showed large seasonal variation; about 99% of the annual total mass flux (49 g m/sup -2/) was collected during the austral summer and fall (January-March). Settling particles consisted primarily of biogenic silica, organic carbon, calcium carbonate, and lithogenic material. Biogenic silica and lithogenic material predominated settling particles, comprising 36% and 30% of the total mass flux, respectively, followed by organic carbon, 11% and calcium carbonate, merely 0.6%. The annual organic carbon flux was 5.4 g C m/sup -2/ at 1000 m in the eastern Bransfield Strait, which is greater than the central Strait flux. The relatively lower flux of organic carbon in the central Bransfield Strait may be caused by a stronger surface current in this region. Organic carbon flux estimates in the eastern Bransfield Strait are the highest in the Southern Ocean, perhaps because of the fast sinking of fecal pellets, which leads to less decomposition of organic material in the water column. Approximately 5.8% of the organic carbon produced on the surface in the eastern Bransfield Strait is exported down to 1000 m; this percentage exceeds the maximum EF/sub 1000/ values observed in the Atlantic and Southern Oceans. The eastern Bransfield Strait appears to be the most important site of organic carbon export to the deep sea in the Southern Ocean.

Stable isotope and rare earth element geochemistry of the Baluti carbonates (Upper Triassic), Northern Iraq

  • Tobia, Faraj Habeeb
    • Geosciences Journal
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    • v.22 no.6
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    • pp.975-987
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    • 2018
  • Stable isotope ratios of $^{18}O/^{16}O$ and $^{13}C/^{12}C$ and rare earth elements geochemistry of the Upper Triassic carbonates from the Baluti Formation in Kurdistan Region of Northern Iraq were studied in two areas, Sararu and Sarki. The aim of the study is to quantify the possible diagenetic processes that postdated deposition and the paleoenvironment of the Baluti Formation. The replacement products of the skeletal grains by selective dissolution and neomorphism probably by meteoric water preserved the original marine isotopic signatures possibly due to the closed system. The petrographic study revealed the existence of foraminifers, echinoderms, gastropods, crinoids, nodosaria and ostracods as major framework constituents. The carbonates have micritic matrix with microsparite and sparry calcite filling the pores and voids. The range and average values for twelve carbonate rocks of ${\delta}^{18}O$ and ${\delta}^{13}C$ in Sararu section were -5.3‰ to -3.16‰ (-4.12‰) and -2.94‰ to -0.96‰ (-1.75‰), respectively; while the corresponding values for the Sarki section were -3.69‰ to -0.39‰ (-2.08‰) and -5.34‰ to -2.70‰ (-4.02‰), respectively. The bivariate plot of ${\delta}^{18}O$ and ${\delta}^{13}C$ suggests that most of these carbonates are warm-water skeletons and have meteoric cement. The average ${\Sigma}REE$ content and Eu-anomaly of the carbonates of Sararu sections were 44.26 ppm and 1.03, respectively, corresponding to 22.30 ppm and 0.93 for the Sarki section. The normalized patterns for the carbonate rocks exhibit: (1) non-seawater-like REE patterns, (2) positive Gd anomalies (average = 1.112 for Sararu and 1.114 for Sarki), (3) super chondritic Y/Ho ratio is 31.48 for Sararu and 31.73 for Sarki which are less than the value of seawater. The presence of sparry calcite cement, negative $^{13}C$ and $^{18}O$ isotope values, the positive Eu anomaly in the REE patterns (particularly for Sararu), eliminated Ce anomaly ($Ce/Ce^{\ast}$: 0.916-1.167, average = 0.994 and 0.950-1.010, average = 0.964, respectively), and Er/Nd values propose that these carbonates have undergone meteoric diagenesis. The REE patterns suggest that the terrigenous materials of the Baluti were derived from felsic to intermediate rocks.

Studies on the Coating Structure and Printability of Coated Paper(III) - Effect of the interaction with pigments and ionic latices on the property of coated paper - (도공층 구조 및 도공지의 인쇄적성에 관한 연구(제3보) - 도공용 안료와 이온성 라텍스와의 상호작용이 도공지 품질에 미치는 영향 -)

  • Park, Kyu-Jae;Lee, Yong-Kyu
    • Journal of the Korean Wood Science and Technology
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    • v.27 no.3
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    • pp.73-81
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    • 1999
  • This paper was intended to evaluate the effect of the blending condition of pigments on the packing structure of coating color and the interaction between pigments and latices on the optical and interior properties of coated paper. It has been studied many ways to modify the coating structure to induce the interaction among coating components as followings ; 1) to use dispersant for pigment, 2) to control the charge density and the type of surface charge of latex, 3) to support the water retention by adding water retention agent or flow modifier. This paper was performed through the introduction of interaction between pigments which were two kinds of clays and one precipitated calcium carbonate(PCC) and ionic latices of which anionic and amphoteric respectively under the certain blending condition of pigments where their blending ratio of clays to calcium carbonate was 70pph to 30pph. The reason is that packing volume of pigments was highest in that region and thixotropical behavior appears in measuring rheology of coating color. We measured the properties of coating color, interaction with pigments and latex, and properties of coated paper and its printability. As a results, we could find out that amphoteric latex had a great influence on the interaction with pigments, especially clays, no matter what grade and also affected the coating structure significantly in case that this blending condition was 70(clays) to 30(PCC). It produced a powerful effect on the forming of bulky and smooth coating structure and in turn improved the printability of coated paper.

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Anodic Oxidation Behavior of AZ31 Magnesium Alloy in Aqueous Electrolyte Containing Various Na2CO3 Concentrations

  • Moon, Sungmo;Kim, Yeajin
    • Journal of Surface Science and Engineering
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    • v.49 no.4
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    • pp.331-338
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    • 2016
  • In this work, anodic oxidation behavior of AZ31 Mg alloy was studied as a function of $Na_2CO_3$ concentration in electrolyte by voltage-time curves and observation of surface appearances and morphologies after the anodic treatments, using optical microscopy and confocal scanning laser microscopy (CSLM). The voltage-time curves of AZ31 Mg alloy surface and surface appearances after the anodic treatments showed three different regions with $Na_2CO_3$ concentration : region I, below 0.2 M $Na_2CO_3$ where shiny surface with a number of small size pits; region II, between 0.4 M and 0.6 M $Na_2CO_3$ where dark surface with relatively low number of large size burned or dark spots; region III, more than 0.8 M $Na_2CO_3$ where bright surface with or without large size dark spots were obtained. The anodically treated AZ31 Mg alloy surface became significantly brightened with increasing $Na_2CO_3$ concentration from 0.5 M to 0.8 M which was attribute to the formation of denser and smoother surface films. Pits and porous protruding reaction products were found at relatively large size and small size spots, respectively, on the AZ31 Mg alloy surface in low concentration of $Na_2CO_3$ less than 0.2 M. The formation of pits is attributed to the result of repetition of the formation and detachment of porous anodic reaction products. Based on the experimental results obtained in this work, it is concluded that more uniform, denser and smoother surface of AZ31 Mg alloy could be obtained at more than 0.8 M $Na_2CO_3$ concentration if there is no other oxide forming agent.

Effect of the applied voltage of pulsed electric fields and temperature on the reduction of calcium ion concentration (고전압 펄스 전계의 인가전압과 온도가 수중 칼슘 농도 저감에 미치는 영향)

  • Kim, Jae-Hyun;Chang, In-Soung
    • Journal of Korean Society of Water and Wastewater
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    • v.33 no.2
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    • pp.95-101
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    • 2019
  • High voltage impulse(HVI) has been gained attention as an alternate technique controlling $CaCO_3$ scale formation. Investigation of key operational parameters for HVI is important, however, those had not been reported yet. In this study, the effect of temperature and applied voltage of HVI on $Ca^{2+}$ concentration was studied. As the applied voltage from 0 to 15kV and the temperature increased from 20 to $60^{\circ}C$, the $Ca^{2+}$ concentration decreased, indicating that the aqueous $Ca^{2+}$ precipitated to $CaCO_3$. The $Ca^{2+}$ concentration decreased up to 81% under the condition of 15kV and $60^{\circ}C$. Rate constant for the precipitation reaction, k was determined under different temper1ature and voltage. The reaction rate constant under the 15kV and $60^{\circ}C$ condition was evaluated to $66{\times}10^{-3}L/(mmol{\cdot}hr)$, which was 5 times greater than the k of the reaction without HVI at same temperature. The increases in k by HVI at higher temperature region(40 to $60^{\circ}C$) was much greater than at lower temperature region(20 to $40^{\circ}C$), which implies temperature is more important parameter than voltage for reducing $Ca^{2+}$ concentration at high temperature region. These results show that the HVI induction accelerates the precipitation to $CaCO_3$, particularly much faster at higher temperature.