• 대한두경부종양학회지
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• 제31권2호
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• pp.6-10
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• 2015

Background and Objective : Papillary thyroid microcarcinoma(PTMC) is known as slow growing cancer with good prognosis. However, extrathyroidal extension may increase the risk of cervical lymph node metastasis and local invasion to surrounding structures. The aim of this study was to assess the characteristic features of the tumor invading the posterior thyroid capsule. Material and Methods : We made a retrospective review of 123 PTMC patients with thyroid capsule invasion, pathologically staged as T3 or T4. 74 patients (60.2%) had invasion to posterior thyroid capsule (group A) while 49 patients (39.8%) had invasion to-anterior thyroid capsule or anterior wall of trachea (group B). We assessed the clinicopathologic factors of the patients according to the location of capsular invasion of PTMC. Results : There was no difference regarding age, gender, T and N classification and incidence of lymph node metastasis between two groups. Local invasion rate to recurrent laryngeal nerve was 6.8% in patients with posterior thyroid capsule invasion, while the incidence was zero in those with capsular invasion to other locations Conclusion : Increased risk of local invasion to the recurrent laryngeal nerve should be considered in patients with PTMC presenting invasion of the posterior capsule.

• 한국멀티미디어학회논문지
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• 제9권12호
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• pp.1669-1680
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• 2006

This paper explains that the RF systems for hi-directional wireless capsule endoscopes were designed and implemented. The designed RF systems for a capsule endoscope can transmit the images of intestines from the inside to the outside of a body and the behavior of the capsules can be controlled by an external controller simultaneously. The hi-directional wireless capsule endoscope consists of a CMOS image sensor, FPGA, LED, battery, DC to DC Converter, transmitter, receiver, and antennas. The transmitter and receiver which were used in the hi-directional capsule endoscope, were designed and fabricated with $10mm(diameter){\times}3.2mm(thickness)$ dimensions taking into the MPE, power consumption, system size, signal to noise ratio and modulation method. The RF systems designed and implemented for the hi-directional wireless capsule endoscopes system were verified by in-vivo experiments. As a result, the RF systems for the hi-directional wireless capsule endoscopes satisfied the design specifications.

• 한국어류학회지
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• 제22권4호
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• pp.217-224
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• 2010

참홍어(Raja pulchra)는 서해지역에서 산업적으로 활용도가 높고 개체군 크기의 축소가 예상되므로 인공증식 기술 개발과 보존을 위해 일련의 연구를 수행하였다. 이 연구는 연중 대형 난각의 형태로 다회 산란하는 특성과 완전한 형태로 부화하는 치어의 특징을 기록하였다. 난소 내 난은 평균 179.8 (54~247)개로 직경이 5가지 무리로 구분되어 순차적인 산란에 기여하는 특성을 보였다. 난각은 다른 홍어류의 종과 구분되는 특징적 구조를 보였으며, 하나의 난각내에 포함되는 배의 수는 2~6개 범위이었다. 아울러 난각내에서 발생하는 자어와 부출 직전에 해당하는 치어의 형태적 특징 및 변화를 분석하여 기술하였다.

• 센서학회지
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• 제17권1호
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• pp.1-8
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• 2008

Recently, capsule endoscope was developed to observe small intestine in human body. However, the capsule does not have any locomotive ability, which reduces the benefit of the capsule endoscope. Many researches have done to give locomotion to the capsule, still it consumes too much power to generate the motion by small battery. One of the moving method is electrical stimulus that consumes less power than many methods. The electrical stimulus method causes contraction in the small intestine, and it moves the capsule. Some of papers showed it is possible to guide the capsule by electrical stimulus, however the relationship between electrical stimulus at the mucous and contraction force in the small intestine is not reported, yet. In this paper, the mucous in the small intestine was stimulated, and measured the contraction force in the small intestine is shown. The result shows, the relationship between electrical stimulus parameters (voltage, duration) and contraction force. Also, equation between electrical stimulus parameters and contraction force is roughly induced.

• 한국소음진동공학회논문집
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• 제15권12호
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• pp.1370-1377
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• 2005

The bottom structure of an instrumented capsule is a part which is joined at the receptacle of the flow tube in the reactor in-core. A geometrical change of the bottom structure has an effect on the pressure drop and the vibration of the capsule. The out-pile test to evaluate the structural integrity of the material capsule called 04M-17U was performed by using a single channel and a half core test loop. From the pressure drop test, the optimized diameter of the cone shape's bottom structure which satisfies HANARO's flow requirement (19.6 kg/s) is 71 mm. The maximum displacement of the capsule measured at the half core test loop is lower than 1.0 mm. From the analysis results, it is found that the test hole will not be interfered with near the flow tubes because its displacement due to the cooling water is very small at 0.072 mm. The fundamental frequency of the capsule under water is 9.64 Hz. It is expected that the resonance between the capsule and the fluid flow due to the cooling water in HANARO's in-core will not occur. Also, the new bottom structure of a solid cone shape with 71 mm in diameter will be applicable to the material and special capsules in the future.

• 한국통신학회논문지
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• 제37권4C호
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• pp.329-337
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• 2012

캡슐 내시경은 인체 내부의 소화기관 병변을 조사할 수 있는 캡슐 모양의 전자장치로서 인체 내에 케이블을 삽입하는 기존 푸시 타입(push-type)내시경과는 달리 환자에게 공포와 고통을 주지 않는 시술로 인식되고 있어, 최근 환자와 의사 모두에게 큰 관심을 끌고 있다. 이 기술은 바이오 기술(BT), 정보통신 기술(IT), 나노 기술(NT) 등의 성숙과 융합으로 2000년에 들어와 처음으로 가능하게 되었으며, LED를 포함한 광학계와 이미지 센서, 통신 모듈, 파워 모듈 등으로 구성되어 있다. 캡슐 내시경은 첨단 기술의 총체로 유비쿼터스 시대에 다양한 기술 분야의 핵심 기술을 필요로 한다. 따라서 본 논문에서는 캡슐 내시경의 구성에 관해 소개하고, 현재 데이터 전송을 위해 사용되고 있는 대표적인 RF 무선 통신 방식 및 인체 통신 시스템 방식에 대해 비교하였다. 아울러 현재 상용된 캡슐 내시경의 사양을 비교 분석하고, 미래의 캡슐 내시경의 진화 방향과 기술적 도전 과제를 제시하였다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 추계학술대회논문집
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• pp.782-787
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• 2005

The bottom structure of an instrumented capsule is a part which is joined at the receptacle of the flow tube in the reactor in-core. A geometrical change or the bottom structure has an effect on the pressure drop and the vibration of the capsule. The out-pile test to evaluate the structural Integrity of the material capsule called 04M-l7U was performed by using a single channel and a half core test loop. From the pressure drop test, the optimized diameter of the cone shape's bottom structure which satisfies HANARO's flow requirement (19 6 kg/s) is 71 mm. The maximum displacement of the capsule measured at the half core test loop is lower than 1.0 mm. From the analysis results, it is found that the test hole will not be interfered with near the flow tubes because its displacement due to the cooling water is very small at 0.072 mm. The fundamental frequency of the capsule under water is 9.64 Hz. It is expected that the resonance between the capsule and the fluid flow due to the cooling water in HANARO's In-core will not occur. Also, the new bottom structure of a solid cone shape with 71 mm in diameter will be applicable to the material and special capsules in the future.

• Advances in aircraft and spacecraft science
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• 제6권3호
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• pp.239-256
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• 2019

This study develops a dual purpose: i) evaluating the effects of two different Mars atmosphere models (NASA Glenn and GRAM-2001) on aerodynamics of a capsule (Pathfinder) entering the Mars atmosphere, ii) verifying the feasibility of evaluating the ambient density and pressure by means of the methods by McLaughlin and Cassanto, respectively and therefore to re-build the values provided by the models. The method by McLaughlin relies on the evaluation of the capsule drag coefficient, the method by Cassanto relies on the measurement of pressure at a point on the capsule surface in aerodynamic shadow. The study has been carried out computationally by means of: i) a code integrating the equations of dynamics of the capsule for the computation of the entry trajectory, ii) a DSMC code for the solution of the flow field around the capsule in the altitude interval 50-100 km. The models show consistent differences at altitudes higher than about 40 km. It seems that the GRAM-2001 model is more reliable than the NASA Glenn model. In fact, the NASA Glenn model produces, at high altitude, temperatures that seem to be too low compared with those from the GRAM-2001 model and correspondingly very different aerodynamic conditions in terms of Mach, Reynolds and Knudsen numbers. This produces pretty different capsule drag coefficients by the two models as well as pressure on its surface, making not feasible neither the method by McLaughlin nor that by Cassanto, until a single, reliable model of the Mars atmosphere is not established. The present study verified that the implementation of the Cassanto method in Mars atmosphere should rely (such as it is currently) on pressure obtained experimentally in ground facilities.

• 약학회지
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• 제43권2호
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• pp.150-159
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• 1999

Hollow type suppositories inserted polyvinyl alcohol (PVA) hydrogel capsule containing propranolol·HCI (PPH) were prepared using different bases, polyethylene glycol (PEG), Witepsol H-15 (WH-15) and Witepsol W-35 (WW-35) to improve the controlled release of PPH. The release of PPH from the hollow type suppository inserted PVA hydrogel capsule was retarded than that from PEG, WH-15, or WW-35 hollow type suppositories in rat rectal cavity. When the suppositories were administered to rats, the controlled release of PPH was proved by the plasma concentration-time-profiles of PPH. No significant difference (p〈0.05) among the three different hollow type suppositories was observed in terms of AUC and MRT of PPH. WH-15 hollow type suppository inserted 12% of PVA hydrogel capsule caused irritation to rat rectal mucosa. However, the WH-15 hollow type suppository inserted PVA hydrogel capsule caused no severe irritation on rectal mucosa. The application of the hollow type suppositories using PVA in sustained rectal delivery of drugs might be feasible.

• 소음진동
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• 제10권2호
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• pp.261-268
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• 2000

The instrumented capsule is subjected to flow-induced vibration(FIV) due to the flow of the primary coolant and then the structural integrity of the capsule during irradiation in the HANARO reactor is an issue of major concern. For this purpose the acceleration was measured by four accelerometers attached to the protection tube of the capsule mainbody and the displacement of test holes was calcultated using commercial finite element program ANSYS to evaluate the structural interference with the neighboring flow tubes under the reactor operating condition. The calculated displacements of test holes in the reactor in-core were found to be lower than the values of allowable design criteria.