• 한국콘텐츠학회논문지
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• 제16권4호
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• pp.144-152
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• 2016

본 연구는 의과대학을 포함하지 않은 보건의료대학에서 실물(시신)실습이 용이하지 않다는 사실에 근거하여, 인체해부학 수업에서 골학실습을 시행했을 때 맨눈해부학의 교육개선 효과가 있는지 살펴볼 목적으로 실시한 국내 최초의 연구이다. 연구방법은 임상병리학과 1학년 학생을 대상으로 인체해부학 수업에 골학실습을 실시하였고 실습 전 후에 자기보고식 설문과 실습 종료 후 지문평가 하였다. 설문지와 지문평가지의 각 문항은 고등교육 교과과정과 성별에 따라 분석하였다. 연구결과, 골학실습이 해부학수업의 흥미를 유발할 뿐만 아니라 해부학 수업을 이해하는데 도움이 되었고, 실습 후 대부분의 학생들은 뼈의 이름을 잘 알고 있었으나 이과보다는 문과출신 학생이 뼈의 해부학적 방향을 묻는 질문에 매우 취약했다. 그리고 대부분의 학생은 골학실습 후에도 대부분의 학생들은 실물실습을 하고자 하는 바람을 가지고 있었다. 결론으로 골학실습은 의과대학을 포함하지 않은 보건의료대학 임상병리학과 학생에게 해부학수업에 대한 기대 부응 및 학습효과의 증대를 가져왔다. 본 연구를 통해 맨눈해부학 교육은 이론뿐만 아니라 실습이 병행한다면 학습효과를 높일 수 있음을 제언한다.

• 약학회지
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• 제58권3호
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• pp.171-180
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• 2014

To enhance the in vitro permeation of lovastatin through excised hairless mouse and human cadaver skins, solubility was determined in various hydrophilic and lipophilic vehicles, and the effects of vehicles and penetration enhancers on the skin permeation from solution formulations were investigated. Solubility of lovastatin was highest in N-methyl-2-pyrrolidone (NMP) ($278.2{\pm}10.1$ mg/ml) and dimethyl sulfoxide (DMSO) ($162.2{\pm}9.7$ mg/ml). Among different pure vehicles used, NMP, DMSO, propylene glycol and isopropyl myristate provided some drug permeation ($6.9{\pm}1.1$, $5.9{\pm}1.6$, $3.0{\pm}0.5$ and $2.2{\pm}0.3{\mu}g/cm^2$ at 24 hr, respectively) through hairless mouse skin. The addition of oleic acid, linoleic acid and oleyl alcohol to DMSO showed the maximum permeation at around 5 v/v%, however, capric acid and caprylic acid had no enhancing effect. The increase of enhancer concentrations showed bell-shaped permeation rate, suggesting the presence of optimal concentration in lovastatin penetration. Increasing donor concentration from 10 mg/ml to 80 mg/ml in DMSO and a cosolvent of DMSO, NMP and DGME (3 : 3 : 4 v/v) did not show significant dose dependent permeation in both hairless mouse and human cadaver skins. The maximum lovastatin flux through human cadaver skin was found to be $0.87{\pm}0.46{\mu}g/cm^2$/hr with 5 v/v% linoleic acid and donor dose of 4 mg/0.64 $cm^2$ in the cosolvent. These results suggest that transdermal delivery of lovastatin would be feasible by establishing the optimal concentrations of donor dose and unsaturated fatty acids in appropriate vehicles.

• 한국토양비료학회지
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• 제45권3호
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• pp.404-409
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• 2012

본 연구는 랜더링처리 가축사체 부산물의 농업적 재활용을 위한 퇴비화의 최적 톱밥 혼합조건을 구명하기 위하여 랜더링처리 가축사체와 톱밥의 비율을 100 : 0, 50 : 50 및 30 : 70으로 혼합하여 퇴비화 초기의 물질변환과 퇴비화 완료 후 퇴비 품질을 조사하였다. 퇴비의 온도, pH, Ammonia 및 $CO_2$의 발생은 시험개시 3일째 급격히 증가하였으며, 그 이후 시간이 지남에 따라 감소하였고, 유기물함량은 각각의 혼합비율에서 큰 차이를 보이지 않았다. 랜더링처리 가축사체와 톱밥의 비율이 100 : 0 처리구에서는 퇴비화의 진행속도가 느리거나 온도가 적정수준까지 상승하지 못하는 등의 문제점이 발생하였고, 30 : 70 처리구에서는 퇴비화 과정에서 유기물대 질소비가 부산물비료 공정규격 50이하를 충족시키지 못하였다. 따라서 랜더링처리 가축사체와 톱밥의 혼합비율은 100 : 0과 30 : 70에 비해서 50 : 50이 가장 적합하였다. 랜더링처리 가축사체와 톱밥을 50 : 50으로 혼합하여 제조된 퇴비의 유기물 규격함량과 유해물질(As, Cd, Cu, Cr, Hg, Ni, Pb 및 Zn)의 함량 및 그 밖의 규격 (유기물대질소비, 염분함량 및 수분함량)을 조사한 결과 비료 공정규격을 충족시키는 결과를 나타내었고, 추후 퇴비의 상품화를 위해서는 병원성 미생물, 대장균, 살모넬라균 및 부숙도 조사를 통한 안전성 검토가 추가적으로 필요할 것으로 판단된다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.57-59
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• 1998

For medical students and doctors, knowledge of the three-dimensional (3D) structure of brain is very important in diagnosis and treatment of brain diseases. Two-dimensional (2D) tools (ex: anatomy book) or traditional 3D tools (ex: plastic model) are not sufficient to understand the complex structures of the brain. However, it is not always guaranteed to dissect the brain of cadaver when it is necessary. To overcome this problem, the virtual dissection programs of the brain have been developed. However, most programs include only 2D images that do not permit free dissection and free rotation. Many programs are made of radiographs that are not as realistic as sectioned cadaver because radiographs do not reveal true color and have limited resolution. It is also necessary to make the virtual dissection programs of each race and ethnic group. We attempted to make a virtual dissection program using a 3D image of the brain from a Korean cadaver. The purpose of this study is to present an educational tool for those interested in the anatomy of the brain. The procedures to make this program were as follows. A brain extracted from a 58-years old male Korean cadaver was embedded with gelatin solution, and serially sectioned into 1.4 mm-thickness using a meat slicer. 130 sectioned specimens were inputted to the computer using a scanner ($420\times456$ resolution, true color), and the 2D images were aligned on the alignment program composed using IDL language. Outlines of the brain components (cerebrum, cerebellum, brain stem, lentiform nucleus, caudate nucleus, thalamus, optic nerve, fornix, cerebral artery, and ventricle) were manually drawn from the 2D images on the CorelDRAW program. Multimedia data, including text and voice comments, were inputted to help the user to learn about the brain components. 3D images of the brain were reconstructed through the volume-based rendering of the 2D images. Using the 3D image of the brain as the main feature, virtual dissection program was composed using IDL language. Various dissection functions, such as dissecting 3D image of the brain at free angle to show its plane, presenting multimedia data of brain components, and rotating 3D image of the whole brain or selected brain components at free angle were established. This virtual dissection program is expected to become more advanced, and to be used widely through Internet or CD-title as an educational tool for medical students and doctors.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2004년도 요약집 춘계학술발표대회
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• pp.386-386
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• 2004

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 추계학술대회 논문집
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• pp.1017-1018
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• 2010

• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.51-58
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• 2009

Purpose: It is to verify learning effect of the instructional media on anatomy classes at a nursing college and to develop an alternative instructional media instead of cadaver. Method: Four groups pretest-posttest experimental design were used. One hundred twenty students who attended an Anatomy lecture in September, 2009 were selected After attending the anatomy lecture, the subjects were divided into four group (30 for each group) conveniently. The heart anatomy knowledge level were measured by a self evaluation questionnaire and quiz before and after a different instructional media being applied for each group including making heart shape using colored clay, taking picture of a real heart, sketching the heart model with color pencil and drawing heart presented in the anatomy textbook. Data was analyzed by t-test, ANNOVA test using the SPSS/PC WIN 12 version. Result: A statistically significant differences in the level of heart anatomy knowledge acquirement was noted after four different instructional media being applied, and four different instructional media was effective to the anatomy practice education. However, no difference in statistical post test results was noted among the four groups. Conclusion: It is recommended that further comparative studies on the learning effect between human cadaver practice and different instructional media is necessary.

• Journal of Korean Neurosurgical Society
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• 제56권6호
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• pp.531-533
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• 2014

We present a case of angiographically confirmed transection of the cisternal segment of the anterior choroidal artery (AChA) associated with a severe head trauma in a 15-year old boy. The initial brain computed tomography scan revealed a diffuse subarachnoid hemorrhage (SAH) and pneumocephalus with multiple skull fractures. Subsequent cerebral angiography clearly demonstrated a complete transection of the AChA at its origin with a massive extravasation of contrast medium as a jet trajectory creating a plume. We speculate that severe blunt traumatic force stretched and tore the left AChA between the internal carotid artery and the optic tract. In a simulation of the patient's brain using a fresh-frozen male cadaver, the AChA is shown to be vulnerable to stretching injury as the ipsilateral optic tract is retracted. We conclude that the arterial injury like an AChA rupture should be considered in the differential diagnosis of severe traumatic SAH.

• 해부∙생물인류학
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• 제31권4호
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• pp.167-170
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• 2018

랑거겨드랑활은 겨드랑에서 흔히 나타나는 변이다. 랑거겨드랑활의 해부학적 그리고 임상적 중요성 때문에 이에 대한 관심이 많다. 학생실습과정에 68세 여성 시신의 오른쪽 팔에서 근육변이가 관찰되었다. 이 근육은 넓은등근의 가쪽모서리에서 근육의 형태로 일어났다. 그 후 힘줄의 형태로 겨드랑동맥과 정중신경을 가로질러 지나간 후 넓어지며 다시 근육의 형태로 큰가슴근에 부착되었다. 우리는 이 근육변이를 소개하고 이것의 임상적 의의에 대해 논의하였다.

• Journal of Medicine and Life Science
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• 제15권1호
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• pp.12-15
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• 2018

Digastric and stylohyoid muscles are located in the suprahyoid region. There have been few studies about the general morphology of stylohyoid muscle and its relationship with digastric muscle. During routine educational dissection, unusual insertion of bilateral stylohyoid muscle was found in the cadaver of a 92-year-old Korean male, whose cause of death was 'aspiration pneumonia'. Stylohyoid muscle arose from the styloid process, and inserted onto the intermediate tendon of digastric muscle and the hyoid bone on both sides. Each digastric muscle normally consists of an anterior belly, intermediate tendon and a posterior belly. In this cadaver, there were two anterior bellies on right side while one anterior belly was found on left side. Stylohyoid muscle ran medial to the intermediate tendon of digastric muscle on both sides. The anatomical relationship between stylohyoid and digastric muscles was reviewed based on morphological and embryological point of view.