• 비파괴검사학회지
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• 제35권2호
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• pp.134-140
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• 2015

전통적인 뜸 요법은 시술자의 주관적이고 정성적인 치료로 인해 환자의 피부에 강한 열 자극이 가해져 심한 통증을 주거나 화상을 입히는 문제점을 갖고 있다. 이러한 한계를 극복하기 위한 대안으로 객관성과 정량화가 가능한 초음파를 활용한 뜸 자극 치료기술이 주목받고 있다. 하지만, 초음파 에너지를 열에너지로 변환하기 위해서는 초음파 치료기기의 음향렌즈에 따른 초음파 집속 특성 분석이 필요하다. 따라서, 본 논문에서는 초음파 집속 특성에 영향을 주는 음향렌즈의 형태(오목렌즈, 계단형 렌즈)에 따른 집속 시뮬레이션을 통해 각 렌즈의 음압 분포, 음압의 크기, 초점의 위치를 계산하였으며, 설계한 렌즈를 제작하여 음압 측정 실험을 통해 음향렌즈의 집속 성능을 검증하였다.

• 한국토양비료학회지
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• 제39권2호
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• pp.80-85
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• 2006

The foliar injuries and absorption rates of calcium compounds in tomato (Lycopersicon esculentum cv. momotaro) and citrus [Shiranuhi(C. Marc. ${\time}C$. sinensis Osbeck)${\time}C$. reticulata Blanco)] were investigated. 0.3, 0.5 and 1.0% of $CaCl_2$, $Ca(NO_3)_2$, $Ca(H_2PO_4)_2$, Ca-EDTA, Ca formate or Ca acetate solution were applied to the leaves of tomato and citrus. The leaf burns were observed only in the foliar applications of Ca-EDTA and $Ca(H_2PO_4)_2$. Ca-EDTA exhibited more serious foliar injury than CaH2PO4. As applied with $^{45}CaCl_2$, $^{45}Ca(NO_3)_2$, $^{45}Ca$ formate or $^{45}Ca$ acetate, the rates of Ca absorptions by tomato and citrus leaves for 7 days were 17 to 32% and 6.6 to 46%, respectively. It meant that the absorption was differently influenced on calcium compounds. In tomato, the order of Ca foliar absorption was $Ca(NO_3)_2$ > Ca formate = $CaCl_2$ > Ca acetate. Although there was no difference in Ca absorption between the adaxial and abaxial parts of tomato leaves, total absorption was greater in expanded leaves than in expanding ones. On the other hand, in citrus Ca foliar absorption from $Ca(NO_3)_2$ or Ca formate was more active than that from $CaCl_2$ or Ca acetate. In conclusion, $Ca(NO_3)_2$ and Ca formate are recommended for the foliar application of Ca in tomato and citrus in order to increase absorption of Ca into their leaves.

• 한국식품위생안전성학회지
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• 제15권2호
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• pp.167-172
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• 2000

최근 동물성 식품 및 지방 섭취 증가로 인한 현대인의 식생활 변화로 혈소판 활성화가 직접적 원인인 뇌 .심혈관질환의 사망률이 증가되고, 성인병 예방과 치료의 대처방안으로 식품의 기능성에 대한 관심이 높아짐에 따라서 천연착색료이며 항균, 항암 작용이 있는 자근(Lithospermum erythrorhizon)으로부터 추출, 분리 . 정제한 분획물에서 혈소판 활성화 억제작용이 있는 생리활성물질을 분리 . 동정하였다 자근에서 methanol, n-hexane, ethyl acetate 등의 용매추출물과 methanol 추출물에 NaOH프 처리한 n-hexane 추출물에 대한 혈소판 응집 억제작용은 collagen의 응집작용에 대하여 n-hexane재추출물이, thrombin의 응집작용에 대하여 ethyl acetate추출물이 큰 억제작용을 보였고, 이러한 추출물에서 컬림 및 HPLC로 분리 .정제한 5개 물질의 화학구조를 IH과 13C-NMR 스펙트라 분석한 결과 shikonin, acethylshi onin, isobutylshikonin, $\alpha$-methyl-n-butylshikonin, $\beta$,$\beta$-dimethylacrylshikonin을 확인하였고, 혈소판 응집 억제작용은 $\beta$,$\beta$-dimethylacrylshi onin$\geq$$\alpha$-methyl-n-butylshikonin>isobutylshikonin>acetylshikonin>shikonin순으로 나타났다. 이상의 결과로부터 자근색소의 생리활성은 shikonin유도체이며 11번 탄소에 치환된 aliphatic 기의 탄소수가 많을수록 억제작용이 강하게 나타난다고 사료된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5389-5393
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• 2014

Background: A clinical pathway (CP) can standardize and improve perioperative care for a number of interventions. In hepatic surgery, however, pertinent evidence is very limited. This study was conducted to implement a CP for hepatocellular carcinoma (HCC) patients undergoing hepatectomy, and to evaluate its effects on hospital costs, length of hospital stay (LOHS) and early clinical outcomes. Materials and Methods: Medical records for HCC patients undergoing hepatectomy were retrospectively reviewed before implementation of a CP (the non-CP group) from March 2012 to August 2012. This information was compared with the data collected prospectively from patients after implementation of the CP (the CP group) between September 2012 and April 2013. Hospital costs, LOHS and early clinical outcomes were evaluated and compared between groups. Results: There were no significant differences in terms of patient clinical characteristics between the two groups. For clinical outcome measures, no significant differences were found in postoperative complications, mortality and readmission rate. The hospital costs were significantly reduced from 24,844 RMB in the non-CP group to 19,761 RMB in the CP group (p<0.01). In addition, patients of the CP group also had shorter LOHS compared with the non-CP group (8.3 versus 12.3 days, p<0.001). Conclusions: The CP proved to be an effective approach to minimize hospital costs and LOHS with hepatectomy for HCC without compromising patient care.

• Journal of Advanced Marine Engineering and Technology
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• 제26권1호
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• pp.37-47
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• 2002

Recently gasoline direct injection method has been applied to gasoline engine to reduce fuel consumption rate by controlling fuel air mixture on lean condition by means of stratified charging, and to reduce simultaneously. Pollutant emissions especially NOx and CO by lowering the combustion temperature. But difficulty of controling local fuel air ratio at ignition area in flammability limit unavoidably appeared, because it is merely controlled by injection timing with spatial and temporal distribution of fuel mixture. In this study, the authors devised a uniquely shaped combustion chamber so called three-chamber GDI engine, intended to keep the more reliable fuel air ratio at ignition area. The combustion chamber is divided into three regions. The first region is in the rich combustion division, where the fuel is injected from the fuel injection valve and ignited by the spark plug. The second region is in the lean combustion division, where the combustion gas from the rich combustion division flows out and burns on lean condition. And the last region is in the main combustion division ie in the cylinder, where the gas from the above two combustion divisions mixed together and completes the combustion during expansion stroke. They found that the stable range of operation of three-chamber GDI engine on low-load condition exists in the lean area of average equivalence ratio. And they also found that the reformed engine reveals less specific fuel consumption and less pollutant emissions compared with conventional carburettor type gasoline engine.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1529-1534
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• 2015

Introduction: Overexposure to sun radiation and particularly its accumulation during childhood and adolescence is a significant risk factor for skin cancer development. The sun burn is particularly important. Aim: To estimate sun burn incidence in young pupils in a coastal area of Greece. Materials and Methods: Two surveys were conducted in a school population in the same district in Greece, over different periods of time, in young people 9 to 18 years old (n=2 977). Anonymous questionnaires were completed. Levels of significance were two-tailed and statistical significance was set at p=0.05. SPSS 17.0 software was used for statistical analysis. Results: From the individual characteristics of the participants it was shown that the majority of them had dark hair and fair skin, whereas a significant percentage reported the existence of moles on face and their body (83.4% vs 68.1%). The sun burn incidence was high in adolescents and the younger pupils (41.9% vs 55.6%). The younger aged children who were living in an urban area had significantly higher rates of sun burn than those living in semi-urban areas (33.8% vs 24.8%, p=0.020). As far as the knowledge of pupils about the risks of sun radiation it was shown that the elementary school pupils had better knowledge than those at high school. Finally, those with better knowledge had the fewer sun burns (Mean 2.83 SD 0.87, p<0.001). Conclusions: The contribution of knowledge to the decrease of sun burn incidence is important as long as this is continuous. Therefore, the education should concern not only children but also teachers and parents in the context of continuous and systematic programs of health education.

• 한국항행학회논문지
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• 제19권4호
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• pp.278-287
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• 2015

항공기 배기가스가 지구의 현재와 미래의 기후에 미치는 잠재적 영향력은 항공산업계가 당면하고 있는 매우 중요한 환경 이슈 중 하나이다. 온실가스 배출의 잠재적 악영향에 대한 우려가 증가함에 따라 항공기의 배기가스 배출을 줄이고 기후에 관한 항공기의 영향을 완화하는 수단 중 하나로 항공기 배기가스를 산정하고 예측하는 시스템 개발의 필요성이 제기되고 있다. 따라서 본 연구에서는 영국 Lissys사에서 개발한 Piano-X 소프트웨어를 사용하여 3가지 항공기 급에 대한 다양한 비행거리와 경로에 대해 유상하중의 변화에 따른 항공기 온실가스 배출량을 산정하였다. 다양한 항속거리와 고도에 따른 경제속도, 장거리 순항속도, 최대 운항거리 속도에 대해 연료소모량도 분석하였다.

• Nutrition Research and Practice
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• 제8권1호
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• pp.33-39
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• 2014

Obesity occurs when a person's calorie intake exceeds the amount of energy burns, which may lead to pathologic growth of adipocytes and the accumulation of fat in the tissues. In this study, the effect and mechanism of pear pomace extracts on 3T3-L1 adipocyte differentiation and apoptosis of mature adipocytes were investigated. The effects of pear pomace extract on cell viability and the anti-adipogenic and proapoptotic effects were investigated via MTT assay, Oil red O staining, western blot analysis and apoptosis assay. 3T3-L1 preadipocytes were stimulated with DMEM containing 10% FBS, 0.5 mM 3-isobutyl-1-methylxanthine (IBMX), $5{\mu}g/ml$ insulin and $1{\mu}M$ dexamethasone for differentiation to adipocytes. 3T3-L1 cells were cultured with PBS or water extract of pear pomace. Water extract of pear pomace effectively inhibited lipid accumulations and expressions of PPAR-${\gamma}$ and $C/EBP{\alpha}$ in 3T3-L1 cells. It also increased expression of p-AMPK and decreased the expression of SREBP-1c and FAS in 3T3-L1 cells. The induction of apoptosis was observed in 3T3-L1 cells treated with pear pomace. These results indicate that pear pomace water extract inhibits adipogenesis and induces apoptosis of adipocytes and thus can be used as a potential therapeutic substance as part of prevention or treatment strategy for obesity.

• 한국항공우주학회지
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• 제37권9호
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• pp.843-854
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• 2009

우리나라의 달탐사를 위하여, 저추력을 이용한 최적의 지구-달 천이궤적 설계를 진행하였다. 탐사선의 추력 형태는 등저추력과 가변저추력 모두를 적용하였으며 각각에 대한 탐사선의 지구 출발부터 달 포획에 이르는 전반적인 모든 단계에 대한 비행 궤적이 설계되었다. 보다 실질적인 우주 환경의 모사를 위하여 행성의 정밀 위치는 JPL의 정밀 천체력인 DE405 천체력을 이용하였으며 지구, 달, 태양의 중력에 의한 섭동과 지구 $J_2$항에 의한 영향을 포함한 N-체의 동력학 방정식이 사용되었다. 탐사선이 지구 근처에 있을 때, 추력의 방향각은 항상 거리의 접선방향이고, 가변저추력을 이용한 경우가 등저추력을 이용한 경우보다 연료를 약 5% 정도 더 절감할 수 있음을 확인하였다. 본 연구에서 구현 및 제시된 저추력을 이용한 최적의 달 탐사 임무 설계 알고리즘과 그 결과는 미래 한국의 달 탐사를 대비하는데 있어서 많은 사전 지식을 제공할 것이며 장차 심화된 임무 설계를 위한 알고리즘의 기반으로 사용될 수 있다.

• Archives of Plastic Surgery
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• 제47권3호
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• pp.223-227
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• 2020

Background After the laws regulating emergency medicine were amended in 2012, regional trauma centers were established in South Korea. Plastic surgeons specialize in the simultaneous surgical care of patients with facial trauma, burns, and complicated wounds. The objective of this study was to evaluate the role of the plastic surgery department in treating severe trauma patients. Methods From January 2012 to December 2018, we enrolled 366 severe trauma patients with an Injury Severity Score (ISS) over 15 who received treatment by specialists in the plastic surgery department. Of these patients, 298 (81.4%) were male, and their mean age was 51.35 years (range, 6-91 years). The average ISS was 22.01 points (range, 16-75 points). Results The most common diagnosis was facial trauma (95.1%), and facial bone fracture (65.9%) was most common injury within this subgroup. Patients were referred to 1.8 departments on average, with the neurosurgery department accounting for a high proportion of collaborations (37.0%). The most common cause of trauma was traffic accidents (62.3%), and the average length of stay in the general ward and intensive care unit was 36.90 and 8.01 days, respectively. Most patients were discharged home (62.0%) without additional transfer or readmission. Conclusions Through this study, we scoped out the role of the specialty of plastic surgery in the multidisciplinary team at regional trauma centers. These results may have implications for trauma system planning.