• Imaging Science in Dentistry
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• v.39 no.1
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• pp.19-25
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• 2009

Purpose: To longitudinally observe the healing process of extracted socket and the alterations of the residual ridge in healthy adult dogs using cone beam CT (CBCT). Materials and Methods: The mandibular premolars of two beagle dogs were removed and the extraction sites were covered with the gingival tissue. CBCTs (3D X-ray CT scanner, Alphard vega, Asahi Co.) were taken at baseline and at 1 week interval for 12 weeks. Radiographic density of extracted wounds was measured on normalized images with a custom-made image analysis program. The amount of alveolar crestal resorption after the teeth extraction was measured with a reformatted three-dimensional image using CBCT. Bony healing pattern of extracted wound of each group was also longitudinally observed and analyzed. Results: Dimensional changes occurred during the first 6 weeks following the extraction of dogs' mandibular premolars. The reduction of the height of residual ridge was more pronounced at the buccal than at the lingual aspect of the extraction socket. Radiographic density of extracted wounds increased by week 4, but the change in density stabilized after week 6. New bone formation was observed at the floor and the peripheral side of extracted socket from week 1. The entrance of extracted socket was sealed by a hard-tissue bridge at week 5. Conclusion: The healing process of extracted wound involved a series of events including new bone formation and residual ridge resorption.

• Proceeding of EDISON Challenge
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• 2015.03a
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• pp.14-23
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• 2015

Alzheimer's disease is one of the most common types of degenerative dementia. As a considerable cause of Alzheimer's disease, neurotoxic plaques composed of 39 to 42 residue-long amyloid beta($A{\beta}$) fibrils have been found in the patient's brain in large quantity. A previous study found that erythrosine B (ER), a red color food dye approved by FDA, inhibits the formation of amyloid beta fibril structures. Here, in an attempt to elucidate the inhibition mechanism, we performed molecular dynamics simulations to demonstrate the conformational change of $A{\beta}40$ induced by 2 ERs in atomistic detail. During the simulation, the ERs bound to the surfaces of both N-terminus and C-terminus regions of $A{\beta}40$ rapidly. The observed stacking of the ERs and the aromatic side chains near the N-terminus region suggests a possible inhibition mechanism in which disturbing the inter-chain stacking of PHEs destabilizes beta-sheet enriched in amyloid beta fibrils. The bound ERs block water molecules and thereby help stabilizing alpha helical structure at the main chain of C-terminus and interrupt the formation of the salt-bridge ASP23-LYS28 at the same time. Our findings can help better understanding of the current and upcoming treatment studies for Alzheimer's disease by suggesting inhibition mechanism of ER on the conformational transition of $A{\beta}40$ at the molecular level.

• Journal of Korean Society on Water Environment
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• v.31 no.5
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• pp.460-467
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• 2015

We analyzed the formation of phytoplankton community and the occurences of odorus compound from benthic cyanobacteria in North, South Han-River, Paldang-Lake and Kyeongan-Stream sediments. Sediments were incubated in different water temperature. Akinetes were found (0~500 cells/g) with the highest number on sediment in Yangsoo railroad bridge (YC). The result showed that Anabaena ranged between $0.02{\sim}0.53{\times}10^3cells/mL$ in Sambong (SB), YC, Mukhyen-Stream (MS), Paldang-Lake (P2) and Kyeongan-Stream (KK). The total 68 taxa of phytoplankton were observed during the incubation period. A standing crop of phytoplankton was in the range of $0.13{\sim}8.97{\times}10^3cells/mL$ and Microcystis appeared in SB, YC, P2 and KK sites with $20{\sim}25^{\circ}C$ temperature. In South Han-River (P3), Oscillatoria tenuis was dominant at $25^{\circ}C$ temperature. The concentration of geosmin was the highest in SB-$15^{\circ}C$ (25.5 ng/L), and the concentration of 2-MIB was the highest in P3-$25^{\circ}C$ (286.8 ng/L). Odorous compounds were detected in all the temperature conditions from each site. Our results indicate that the dominant benthic cyanobacteria (O. tenuis, O. limosa, Phormidium tenue and Pseudanabaena limnetica) have high correlation with the occurrence odorous compounds and 2-MIB.

• Restorative Dentistry and Endodontics
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• v.38 no.4
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• pp.258-262
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• 2013

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

• Environmental Engineering Research
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• v.14 no.4
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• pp.220-225
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• 2009

The water quality in eutrophic lakes is affected by serious problems, such as abnormal increasing of Cyanobacteria. The purpose of this study was to investigate the possibility of a modified flotation system using a hybrid technique formed by chemical compounds and an electrostatic bridge. Therefore, experiments using the hybrid technique were performed to measure the zeta potential value on the phytoplankton surface and the removal efficiencies of phytoplankton, ammonia nitrogen, nitrate nitrogen and phosphoric acid. The results were as follows: Firstly, the zeta potential of M.aeruginosa was observed to approach charge neutralization due to adhesion of magnesium hydroxide precipitate on the phytoplankton surface in the pH range 10.5 to 11. Secondly, the concentration of chlorophyll-a decreased from about 150 to 20${\mu}g$g/L, with a maximum removal efficiency of 84% due to coagulation with pH values higher than 10. Thirdly, the N$H_4$-N concentration was observed to decrease from 0.62 to 0.54mg-N/L (13%), and the P$O_4$-P concentration, which is a limiting factor to the formation of algae blooms, decreased from 0.27 to 0.02mg-P/L (92%). These findings suggest that the modified flotation system can be applied for the purification of the raw water of numerous lakes containing high phytoplankton populations and elevated pH.

• Journal of the Speleological Society of Korea
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• no.89
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• pp.46-58
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• 2008

동굴 퇴적물의 형성과정은 1단계 기권 (Atmosphere): 빗방울 (H2O) 이 대기중에서 CO2의 혼합으로 산성비 (H2CO2)가 되어 석회암 (CaCO3)에 떨어져서 최초의 용식작용이 시작된다. 2단계 토양권 (Pedosphere): 산성비와 석회암성분이 합쳐 형성된 가용성 화합물 (Ca(HCO3)2)은 식생부식(植生腐植)에 의한 토양 (Humic acidic soils) 에 의해 기반암의 용식이 촉진 되어 지표에는 Karren과 석문 (석문(石門) Natural Bridge), 와지 (Dolines, Sinkholes) 지형을 형성시키고, 암석의 분순물은 지표에 남겨져서 결국 적색풍화토 (Residuum, Risidual Redish Soils) 를 만든다. 3단계 암권 (Lithosphere): 용식작용에 의해 지상에서 지하 로 확대되어진 모암의 균열을 타고, 지하의 공간이 지하수의 유입과 유출에 의해 점차 확대되어 동공형의 Conduites; Voids; Shaft 이라는 특수지형을 형성시키고,동굴의 천정으로부터 나온 Ca(HCO3)2 는 탄산염의 지속적인 분해 공급에 의해 동굴내에는 종류석, 석순, 유착석 (Speleothem)등의 새로운 동굴지형 (Speleoscape)을 조성하게 된다. 4단계 수권 (Hydrosphere): 동굴의 형성작용을 거친 물은 동굴지하수로 잔여 Calcite를 함유한 채로 유출 (Spring) 된다. 동굴을 떠난 잔여 Calcite는 또다시 하천유역에 침전시켜서 석회화 단구형의 집적지형 (Tufa Formation: Tufa Dam, Tufa Flowstone)을 최종적으로 동굴을 나와 외벽 이나 하천의 바닦에 형성하는 과정을 거치면서 카르스트 지형의 발달과정이 1차적인 순환을 마치게 된다.

• Journal of the Korea Society of Computer and Information
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• v.12 no.6
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• pp.251-259
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• 2007

A Bluetooth ad hoc network can be formed by interconnecting piconets into scatternet. Many algorithms of scatternet formation have been proposed so far. However, these have a problem that takes a long time to reform scatternet, especially for the case of master moving out. In this paper we propose a Fast-Recovery algorithm. which aims at reducing the time of scatternet reformation owing to master moving out. In the algorithm, we select a slave with the weigh similar to its master as Sub-Master from a piconet device table created by the master When a master leaves its piconet is detected by its slaves, the Sub-Master becomes the new master of the piconet instead of the old and directly connect to other slaves and bridge(s) through piconet device table in page state.

• Journal of fish pathology
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• v.25 no.1
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• pp.11-20
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• 2012

C-type lectins are crucial for pathogen recognition, innate immunity, and cell-cell interactions. In this study, a C-type lectin gene was cloned from the rock bream. The full-length RbCTL cDNA was 729 bp with a 429 bp ORF encoding a 164-residue protein. The deduced amino acid sequence of RbCTL had all of the conserved features crucial for its fundamental structure, including the four cysteine residues involved in sulfide bridge formation and potential $Ca^2+$/carbohydrate-binding sites. RbCTL contains a signal peptide one single carbohydrate recognition domain. It showed 29.4% similarity to the C-type lectin of rainbow trout. RbCTL mRNA was predominately expressed in gill and head-kidney tissue and expressed less in peripheral blood leukocytes, trunk-kidney, spleen, liver, intestine and muscle. Expression of RbCTL was differentially upregulated in rock bream stimulated with LPS, Con A/PMA and poly I:C.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.2
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• pp.33-39
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• 1998

A six-beam accelerometer with self-compensated off-axis sensitivity was fabricated onthe selectively diffused (111)-oriented n/n$^{+}$/n silicon substrates by a unique porous silicon micromachining technique, which has self-stip characteristics and highly seletive formation of porous silicon layer during anodic reaction. Also, the characteristics of the fabricated accelerometer were investigated. The sensitivity of the acceleormeter added up outputs of three bridges through a summing circuit was 0.68 mV/g and the nonlinearity was less than 2% of the full scale output. The measured first resonant frequency was 4.236 kHz. When the outputs of three bridges were compared to summing output of bridges obtained through summing circuit, the normal output for Z-axis acceleration exhibited the same value s summing outputs of three bridges without reduction of sensitivity and thus the sensitivity decrease due to additional beam was compensated. Although a maximum off-axis sensitivity in one bridge of the accelerometer showed 17% of normal sensitivity, the off axis sensitivity obtained from summing output of three bridges decreased to 1.0%. Therefore, the self-elimination of off-axis sensitivity can be simply realized by obtaining the output of the sensor through summing circuit.t.

• Korean Journal of Veterinary Pathology
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• v.3 no.1
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• pp.55-59
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• 1999

Metastatic squamous cell carcinoma was described in two female Pere David's deer reared at Everland zoo. Both deer with chronic emaciation had the mass on right maxilla(9$\times$11$\times$15cm or 20$\times$17cm) which was composed of miliary tan creamy contents and encapsulated by connective tissue. The undulating contents in the mass was a1so extended in the underlying or adjacent soft palate, maxillary and frontal sinus causing severe bone destruction. In one deer, two fistula were also noted in the right periocular area. Histologically, the neoplastic masses of both deer consist of anastomosing cords or nests of squamous epithelial cells with intercellular bridge or keratin pearl formation. The neoplastic cells invade deep into the subcutis and bony tissue. Mitotic figure was rare. Multifocal areas of necrosis and hemorrhages were also noted in the dermis. Metastasis to maxilla and ethmoid bones and/or to submandibular lymph node was noted in both cases. The diagnosis was based on the results of histopathology.